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Jurnal Ilmiah Kedokteran Wijaya Kusuma

JIKW
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Published by Universitas Wijaya Kusuma Surabaya

ISSN : 19782071 EISSN : 25805967 DOI : -

Core Subject : Health, Science,

Biochemistry, Genetics & Molecular Biology Medicine & Pharmacology Public Health

Jurnal Ilmiah Kedokteran Wijaya Kusuma (JIKW) is a periodically scientific publication that contains articles written in Indonesia or english. JIKW receive articles in the scope of Biomedical Sciences, degenerative diseases, infections, congenital abnormalities and public health. JIKW published twice a year. The articles will be published in JIKW only manuscript that has never be published or published in other journal. Writers who will publish the article please follow the JIKW guidelines. The entire management process both admission and review the article is done by online.

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Articles 8 Documents

Search results for , issue "Vol 10, No 1 (2021): MARET 2021" : 8 Documents clear

Case Report: Gastric Wall Thickening: Radiological Diagnostic Challenges in Gastric Malignancy Putu Ayu Winda Wirastuti Giri; Nyoman Srie Laksminingsih; Firman Parulian Sitanggang; I Gusti Ayu Sri Mahendra Dewi; I Wayan Juli Sumadi; Luh Putu Iin Indrayani Maker
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 10, No 1 (2021): MARET 2021
Publisher : Universitas Wijaya Kusuma Surabaya

Gastric abnormalities show nonspecific gastrointestinal symptoms and similarly radiological findings. Intra and extra luminal gastric wall thickening are the most common finding in benign and malignant pathologic process. This aim of this case report was to describe several characteristics such as the location and size of the lesion, involvement of the gastric wall and surrounding structures, calcifications, and contrast enhancement pattern which can assist in radiological diagnosis. Several cases at our institution have similar gastrointestinal complaints, however, there were different lesions characteristic found in contrast enhanced abdominal CT scan. The first case 72-years-old man experienced hematemesis with radiologic finding diffuse gastric mucosal thickening as well as homogenous contrast enhancement but without calcification. The second case 37-years-old man complaint dizziness and melena with radiologic finding large tumor more than 10 cm in size, amorph calcification and heterogenous contrast enhancement. The last 60-years-old man case experienced melena and hematemesis, from abdominal CT scan showed irregular gastric mucosal thickening with heterogenous contrast enhancement and fat stranding around the lesion, without calcification. Methods used in these cases were contrast-enhanced abdominal CT scan, esophagogastroduodenoscopy (EGD), and biopsy in order to determine the diagnosis. Contrast-enhanced abdominal CT scan plays a vital role in describing the lesion characteristics which affects the determination of treatment options and future prognosis.

Giant Congenital Melanocytic Nevi (GCMN): Sebuah Laporan Kasus Langka Erico Lemuel Yonathan; Hari Darmawan
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 10, No 1 (2021): MARET 2021
Publisher : Universitas Wijaya Kusuma Surabaya

Giant Congenital Melanocytic Nevi (GCMN) is a nevus which present at birth or arise within the first few weeks of life. Incidence of GCMN is estimated at below 1:20.000 newborns. Lesion of GCMN usually appears with a black or brownish plaque and may have abnormal borders, flat or protruding surface and hypertrichosis. Giant Congenital Melanocytic Nevi (GCMN) is associated with malignant melanoma and neurocutaneous melanocytosis. A male newborn baby is reported to have a giant black hairy plaque, with irregular shape in his head since born. Patient was born naturally, full term, and normal birth weight. The mother has no medication consumption and disease history during pregnancy. In our three years follow up, there are multiple black patches with smaller size in front right and left leg, and the back of the body. The GCMN treatment consists of surgical and non-surgical procedures, psychological support, and lifelong monitoring. In this case, further examination and observation are needed.

Studi Faktor Risiko Preeklamsi terhadap Kejadian Asfiksia Neonatorum di RSUD dr. Sayidiman Magetan Tahun 2018 Vivian Ade Wilsye Maria Mongdong; Rivan Virlando Suryadinata; Sawitri Boengas; Siti Ariffatus Saroh
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 10, No 1 (2021): MARET 2021
Publisher : Universitas Wijaya Kusuma Surabaya

One of the complications of pregnancy which is quite dangerous is preeclampsia. Increased blood pressure is a major indicator for pregnant women from preeclampsia. Various complications lead to increased risk of mortality and morbidity in the mother and fetus. During the birth process, the fetus that is conceived by a mother with preeclampsia, have a higher risk of developing neonatal asphyxia. This study aims was to determine the risk of preeclampsia on the incidence of neonatal asphyxia in dr. Sayidiman Magetan Hospital in 2018. The method used was observational with a cross sectional design. Data were collected using patient medical records. The results showed there was a difference in the incidence of neonatal asphyxia in preeclampsia and non- preeclampsia pregnant women (p = 0.000). Pregnant women with preeclampsia had a higher risk of giving birth with neonatal asphyxia (OR=3,071). In this study, it can be concluded that the risk of incidence of neonatal asphyxia is 3 times higher in preeclampsia than in non-preeclampsia at dr. Sayidiman Magetan in 2018.

Pengaruh Pemberian Minuman Energi Terhadap Kadar Serum Kreatinin Rattus Norvegicus Budi Santo; Dorta Simamora
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 10, No 1 (2021): MARET 2021
Publisher : Universitas Wijaya Kusuma Surabaya

The energy drink is a beverage that is increasingly being used by the community with the aim to improve work performance, vitality, and concentration. The energy drink is also suspected to affect kidney function. This study aims to determine whether there is influence of various brands of energy drinks (M1, M2, M3, M4) of the serum creatinine levels in male rats Rattus norvegicus.This is a study with randomized post test only control group design. The study used male rats Rattus norvegicus as many as 25 animals that were divided into 5 groups. The control group, the group P1 = M1 energy drinks, group P2 = M2 energy drinks, group P3 = M3 energy drinks, group P4 = M4 energy drinks. The energy drinks were given as many as 2.5 ml / 200 g weight / day for 1 month. Cardiac blood sampling performed to measure the levels of serum creatinine and then the results were analyzed using One-Way Anova to compare the levels of serum creatinine in each group of this study. Results of One-Way Anova test obtained by sig α = 0.000 which means there is significant difference between the treatment group and the control group. It can be concluded that the administration of energy drinks to the Rattus norvegicus would be altered the kidney function. It is caused by various substances contained in energy drinks such as taurine, sugar, vitamin B, caffeine, and other supplementary materials.

Cover Volume 10 Nomer 1 tahun 2021 Putu oky ari tania
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 10, No 1 (2021): MARET 2021
Publisher : Universitas Wijaya Kusuma Surabaya

Role of Matrix Metalloproteinase in the Progression of Heart Failure: A Narrative Review Sidhi Laksono; Budhi Setianto; Reynaldo Halomoan
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 10, No 1 (2021): MARET 2021
Publisher : Universitas Wijaya Kusuma Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30742/jikw.v10i1.987

Heart failure (HF) is a cardiovascular disease with a complex pathological pathway and influenced by many factors. Such a complex pathological mechanism would impair cardiac function and structural stability. One that plays a role in maintaining the function and structure of the heart is the extracellular matrix (ECM), and disruption in the extracellular matrix has a role in causing cardiac dysfunction. ECM regulation is associated with matrix metalloproteinase (MMP). Overexpression of matrix metalloproteinases can lead to ECM degradation process which leads to cardiac remodelling. The role of MMP in heart failure is also related to the increased inflammatory response, which is one of the pathways for progression of heart failure. The close association of MMP with the development of heart failure makes MMP a potential biological marker. This article aims was to understand the role of MMP and its mechanisms in cardiac remodelling pathways leading to heart failure. This narrative review suggests that overexpression of MMP can lead to heart failure. Inflammation is one of the factors triggering the expression of MMP. Inflammation will increase the release of pro-inflammatory cytokines, thereby triggering MMP expression. MMP expression imbalance can damage collagen tissue through ECM degradation and damage the structure and function of the heart. MMP can also be used as a biological marker in heart failure cases. The application of MMP as a biological marker can be used to assess the degree of disease severity as well as a predictor of heart failure. In conclusion, MMP has an important role in the development process of heart failure and can be a biological marker in cases of heart failure.

Pendekatan Multilevel Sebagai Upaya Meningkatkan Pemberian ASI Eksklusif Nur Khamidah; Yayi Suryo Prabandari; Detty Siti Nurdiati
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 10, No 1 (2021): MARET 2021
Publisher : Universitas Wijaya Kusuma Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30742/jikw.v10i1.942

Increasing exclusive breastfeeding effort was continued in Jember district. Local government collaborates with USAID to increase breastfeeding promotion program. Health promotion program used multilevel approach. This study aimed to evaluate exclusive breastfeeding program and impact program to increasing breastfeeding in Jember district. This study method used cross sectional study in two population with mix method approach (qualitative and quantitative). Collecting qualitative data was using participative observation, indepth interview and focus group discussion to describing program. Collecting quantitative data was using questionare to evaluate impact program in two populations (120 respondent program and 125 respondent non program). Data was analyzed by open code in qualitative data. To analyzed quantitative data was used chi square. The research result shows that Health promotion program increased exclusive breastfeeding was using multilevel approach. In top level, implementation of the program was regulation government policy number 17, 2013 about save childbirth, initiation breastfeeding and exclusive breastfeeding. In the middle level implementing program by Jember health department and local government clinic through peer breastfeeding support, mother pregnant class and promote by midwife. Lower level evaluation result was that two population program and non program have different significant. Population who give program have 2,4 higher OR value in exclusive breastfeeding than population not give the program. Based on this research it can be concluded that multilevel approach can used to increasing exclusive breastfeeding until six month. Government support was needed to successful program.

Efektivitas Antidiabetes Fraksi Air Daun Karamunting (Rhodomyrtus Tomentosa (Ait.) Hassk.) terhadap Kadar Glukosa Darah dan Sekresi Insulin pada Tikus Model Diabetes Geri Febriyanto; Mgs. Irsan Saleh; Theodorus Theodorus
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 10, No 1 (2021): MARET 2021
Publisher : Universitas Wijaya Kusuma Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30742/jikw.v10i1.1098

This study aims to determine the effectiveness of the water fraction of caramunting leaves (Rhodomyrtus tomentosa (Ait.) Hassk). Against a decrease in blood glucose levels 2 hours post prandial and an increase in insulin levels of male white rats induced by streptozotocin. This research is an in vivo laboratory experimental research. The subjects of this study were 30 male white rats divided into 5 groups, namely positive control using glibenclamide, negative control using Na CMC, treatment group using caramunting leaf water fraction 70mg/ KgBB, 140mg/ KgBB, and 280mg / KgBB. The results showed that the caramunting leaf water fraction group was 70mg/ KgBB. 140mg/ KgBB, and 280m / KgBB effectively reduce blood glucose levels 2 hours post prandial and increase insulin levels. Based on the results obtained, it can be concluded that the water fraction of caramunting leaves (Rhodomyrtus tomentosa (Ait.) Hassk). Effectively reducing blood glucose levels 2 hours post prandial and increasing insulin levels with a dose of 280mg / KgBB is the most effective dose.

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Jawa timur

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