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EFEK ANTIDIABETES HERBA CIPLUKAN (Physalis angulata LINN.) PADA MENCIT DIABETES DENGAN INDUKSI ALOKSAN Sutjiatmo, Afifah B.; Sukandar, Elin Yulinah; Ratnawati, Yulia; Kusmaningati, Suswini; Wulandari, Asri; Narvikasari, Suci
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol 5, No 4 (2011)
Publisher : Indonesian Research Gateway

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Abstract

Antidiabetic effects of water extract of ciplukan (Physalis angulata L.) herbs has been done with the test method of alloxan diabetes induction. Water extract was fractionated using n-hexane, ethyl acetate and water.The results showed that ciplukan water extract dose of 10 mg/kgbw and the water fraction dose of  4.84 mg/kgbw have similar effect with glibenclamide dose of  0.65 mg/kgbw. The phytochemical screening showed that ciplukan water extract contains alkaloids, flavonoids, saponins, polyphenols, steroids and triterpenoids, monoterpenoids and sesquiterpenoids. ABSTRAK Telah dilakukan uji efek antidiabetes ekstrak air herba Ciplukan (Physalis angulata L.) dengan metode uji diabetes induksi  aloksan. Selanjutnya ekstrak air difraksinasi dengan pelarut n-heksan, etil asetat dan air. Hasil uji membuktikan bahwa ekstrak air herba ciplukan dosis 10 mg/kgbb dan fraksi air 4,84 mg/kgbb mempunyai efek antidiabetes yang sama dengan pembanding glibenklamid dosis 0,65mg/kgbb. Hasil penapisan fitokimia menunjukkan bahwa simplisia dan ekstrak air herba ciplukan mengandung alkaloid, flavonoid, saponin, polifenol, steroid dan triterpenoid, monoterpenoid dan seskuiterpenoid.
Co-Authors Afifah B. Sutjiatmo Asri Wulandari Elin Yulinah Sukandar Kusmaningati, Suswini Yulia Ratnawati, Yulia