Napthaleni ,
Departemen Kimia, FMIPA, Institut Pertanian Bogor, Darmaga, Bogor 16680

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ENKAPSULASI KETOPROFEN DENGAN KITOSAN-ALGINAT BERDASARKAN JENIS DAN RAGAM KONSENTRASI TWEEN 80 DAN SPAN 80 Purwantiningsih Purwantiningsih; Napthaleni ,; Mersi Kurniati; Tuti Wukirsari
Makara Journal of Science Vol 14, No 2 (2010): November
Publisher : Directorate of Research and Community Engagement, Universitas Indonesia

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Abstract

Encapsulated Ketoprofen by Chitosan-Alginat based on Type and Variation of Tween 80 and Span 80 Concentration. Ketoprofen has been encapsulated by chitosan-alginate based on types of surfactant and it’s concentration. The variations of concentration either Tween 80 (polietilena sorbitanmonooleat) or Span 80 (sorbitanmonooleat) that used were around (1- 3)% concentrations with stirring around (15-60) minutes. The using of Tween 80 resulted efficiency of encapsulated ketoprofen and nano particle size (100-1000) nm are higher than Span 80.Keywords: encapsulated ketoprofen, chitosan-alginate, Span 80, Tween 80