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Correlation between Obesity and Contraceptive Method on Estrogen and Progesterone Receptors and Human Epidermal Growth Factor Receptor–2 Expression among Breast Cancer Patients in Dr. Moewardi Hospital, Surakarta Agustina, Silvia Ari; Barokah, Liberty
Indonesian Journal of Medicine Vol 4, No 3 (2019)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (326.078 KB)

Abstract

Background: Breast cancer is the number 2 cancer in Indonesia after cervical cancer. Breast cancer increases every year. The formation of breast cancer is stimulated by various factors such as obesity and a history of family planning. In breast cancer, there are three important receptors, namely estrogen (ER) receptors, progesterone receptors (PR), and HER-2/Neu. The purpose of this study was to determine the association of obesity and history of family planning with the estrogen hormone receptor (ER), progesterone hormone receptor (PR), and HER-2/Neu expression in breast cancer patients in the dr. Moewardi Hospital in Surakarta, Central Java.Subjects and Method: This was an analytic observational study carried out at Dr. Moewardi Hospital, Surakarta, Central Java. A sample of 117 pre- and post-menopausal women who performed examinations at the oncology surgical clinic at Dr. Moewardi hospital, Surakarta was selected by total sampling. The dependent variables were estrogen and progesterone receptors and HER-2/Neu expressions. The independent variables were obesity and history of contraceptive method. Data were obtained from the medical record and analyzed by multiple logistic regression.Results: Obesity (OR= 0.29; 95% CI= 0.13 to 0.68; p= 0.004) reduced estrogen hormone receptors and it was statistically significant. History of contraceptive method (OR= 1.18; 95% CI= 0.55 to 2.52; p= 0.680) increased estrogen hormone receptors but it was not statistically signi­ficant. Obesity (OR=0.41; 95% CI= 0.18 to 0.96; p= 0.040) and history of contraceptive method (OR= 0.41; 95% CI= 0.19 to 0.88; p= 0.022) reduced progesterone hormone receptors. Obesity and history of contraceptive method increased Her-2/Neu expression.Conclusion: Obesity reduces estrogen hormone receptors. History of the contraceptive method increases estrogen hormone receptors. Obesity and history of contraceptive method reduce pro­gesterone hormone receptors. Obesity and history of contraceptive method increase Her-2/Neu expression.Keywords: Obesity, contraceptive method, estrogen, progesterone hormones, Her-2/neuCorrespondence: Silvia Ari Agustina. Study Program in Midwifery, School of Health Sciences Achmad Yani, Yogya­karta. Jl. Ringroad Barat Ambarketawang, Gamping, Sleman, Yogyakarta. Phone: (0274) 4342000. Email: silvia_ari99@yahoo.com. Indonesian Journal of Medicine (2019), 4(3): 259-265https://doi.org/10.26911/theijmed.2019.04.03.09
PERAN SUAMI DALAM MEMBERIKAN DUKUNGAN MORIL PERSIAPAN PERSALINAN DI PUSKESMAS PLERET BANTUL Mahmudah, Happy; Barokah, Liberty
MEDIA ILMU KESEHATAN Vol 5 No 1 (2016): Media Ilmu Kesehatan
Publisher : Universitas Jenderal Achmad Yani Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (64.358 KB) | DOI: 10.30989/mik.v5i1.144

Abstract

Background: Husband’s role is very crucial in supporting their wives in a process of delivery. The lack of a husband's role will lead to low participation in caring activities during the pregnancy, childbirth, and postpartum period. Husband should be given knowledge about birth preparedness, which includes the planning of laborand preparing for a decision-maker in a case of emergency. Objective: To determine the role of husband in providing moril support to their wives in labor process at Pleret Bantul Puskesmas. Methodology: This research was descriptive quantitative, conducted at Pleret Bantul Puskesmas in 2015. Thirty-two respondentswere involvedassamplesby total sampling technique. Results:The husband's role in providing moril support on the expected date of birth was mostly high (87.5%). The husband's role in providing moril support during the pregnancy check was high (50.0%). The husband's role in providing moril support during the process of delivery is mostly high (81.3%).The husband's role in providing moril support in planning the labor process was high (59.4%). Conclusion:The role of the husband in providing moril support to their wives in labor process at Pleret Bantul Puskesmas washigh (59.4%). Keywords: Husband’sRole, Moril Support, Childbirth
EFEKTIVITAS PEMBERIAN PISANG AMBON DAN VITAMIN B UNTUK MENURUNKAN HIPEREMESIS GRAVIDARUM DI BPM ENDAH BEKTI Fit Ari Shanti, Elvika; Barokah, Liberty; Rahayu, Budi
Jurnal Media Ilmu Kesehatan Vol 7 No 1 (2018): Media Ilmu Kesehatan
Publisher : Universitas Jenderal Achmad Yani Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (42.663 KB) | DOI: 10.30989/mik.v7i1.218

Abstract

Background: Endocrine system changes during pregnancy are important to keep the pregnancy, fetal growth and post partum recovery. Around 50-90% of pregnant women experience vomit and nausea. To solve those problems, ?pisang ambon? (Musa paradisiacal) consumption is one of choices because of its flavonoid and vitamin B6 which can overcome vomit and nausea in pregnancy. Objective: The aim of this research was to identify the effectiveness between pisang ambon (Musa paradisiacal) consumption and vitamin B6 to reduce hyperemesis gravidarum in BPM Endah Bekti. Methods: A quasy experimental design with two-group posttest only was assigned to 20 pregnant women on their first trimester. First ten sample was given vitamin B6 and the other ten sample were given vitamin B6 plus pisang ambon. Data were then analyzed using two independent mean difference test. Results: The result shows that in vitamin B6 consumption for hyperemesis gravidarum in 10% pregnant women were in the effective category. While in the pisang ambon consumption shows 100% of pregnant women are in the effective category. Conclusion: There is difference in effectiveness between vitamin B6 and pisang ambon consumption to overcome hyperemesis gravidarum (p=0,003<?). Keywords: Hiperemesis gravidarum, vitamin B6, Pisang ambon
Faktor Internal Kejadian Ketuban Pecah Dini di Kabupaten Kulonprogo Barokah, Liberty; Agustina, Silvia Ari
Window of Health : Jurnal Kesehatan Vol 4 No 2 (April 2021 )
Publisher : Fakultas Kesehatan Masyarakat Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33368/woh.v0iNo 2.314

Abstract

Premature rupture of membranes (PROM) is a rupture of the membranes before labor. PROM is still a Disease of Theory because it is not yet known the exact cause, but there are several internal or external conditions thought to be related to premature rupture of membranes. Internal factors include maternal age, parity, polyhydramnios, cervical incompetence and fetal presentation. Complications due to PROM are infections in labor and childbirth, prolonged labor, increased of caesarean section deliveries. The purpose of this study was to determine the internal factors of the incidence Premature rupture of membranes (PROM) in Kulonprogo, Yogyakarta. This study uses analytic surveys with a retrospective approach. Univariate data analysis uses percentage forms and multivariate uses binomial logistic regression analysis. The results showed that internal factors such as parity, gestational age, disporpotion Chepalo Pelvic and c diseases in pregnant had p values (0.031, 0.035, 0,008 dan 0.000) < 0.005. the variable has a significant influence on the incidence of PROM. While the variable location of the fetus and uterine enlargement does not have a partial effect on PROM with a p value (0.816 and 0.857) > 0.005 here is a relationship between internal factors (parity, gestational age, PROM and diseases in pregnant) with the incidence of PROM
PENGARUH PELATIHAN DENGAN MODEL PEMBELAJARAN MAKE A MATCH TERHADAP KETERAMPILAN KADER POSYANDU DALAM MENGGUNAKAN BUKU KIA Zolekhah, Dewi; Barokah, Liberty; Shanti, Elvika Fit Ari
Healthy Tadulako Journal (Jurnal Kesehatan Tadulako) Vol. 7 No. 2 (2021)
Publisher : Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (246.403 KB) | DOI: 10.22487/htj.v7i2.175

Abstract

Buku KIA merupakan buku yang berisi catatan kesehatan ibu dan anak yang dapat dijadikan sebagai pedoman dalam meningkatkan kualitas pelayanan kesehatan ibu dan anak melalui upaya mendeteksi secara dini adanya masalah kesehatan ibu dan anak. Kader diharuskan untuk membaca dan secara bertahap mempelajari buku KIA yang merupakan petunjuk nasional setelah mereka melakukan kegiatan Posyandu sebagai evaluasi atas apa yang telah mereka kerjakan. Terbatasnya informasi dan pelatihan kader yang kurang menyebabkan pengetahuan dan keterampilan kader tentang penggunaan buku KIA rendah. Tujuaan penelitian ini yaitu untuk mengetahui pengaruh pelatihan dengan model pembelajraan kooperatif terhadap keterampilan kader dalam menggunakan buku KIA. Jenis penelitian ini adalah pra eksperimental dengan rancangan (The One Group Pretest Posttest) dengan populasi 30 kader Posyandu sebagai sampel di wilayah kerja Puskesmas. Analisis data menggunakan Wilxocon Sign test, didapatkan p value (0,000) < 0,005. Hasil uji prasyarat parametrik untuk data keterampilan didapatkan data tidak berdistribusi normal, analisis data menggunakan wilcoxon, didapatkan hasil nilai p value 0,000 < 0,005 sehingga terdapat perbedaan yang bermakna keterampilan kader sebelum dan sesudah diberikan pelatihan dengan model pembelajaran kooperatif terhadap keterampilan kader posyandu dalam menggunakan buku KIA.