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All Journal Media Ilmu Keolahragaan Indonesia Jurnal Respirologi Indonesia
Tarigan, Amira Permatasari
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Health Professions Medicine & Pharmacology

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The Relationship Between Level of Transforming Growth Factor - β with Pulmonary Fibrosis in Post Pulmonary Tuberculosis in Medan Christine, Tamara; Tarigan, Amira Permatasari; Nainggolan, Nuryunita; Zaluchu, Fotarisman
Jurnal Respirologi Indonesia Vol 40, No 1 (2020)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v40i1.90

Abstract

Background: Untreated or undertreated, pulmonary tuberculosis could cause severe complications until death. After treatment, residual lesions might occur. The presence of residual lesions is varied, including: fibrosis, cavity, bronchiectasis and calcification. Transforming growth factor-β (TGF-β) is a cytokine associated with lung inflammation, which plays a role in lung fibrosis. However, only a few studies have assessed the serum level of TGF-β in post-treatment tuberculosis patients. The main objective of this study was to determine the relationship between TGF-β levels and pulmonary fibrosis in patients with pulmonary tuberculosis. Methods: Among 51 patients that had undergone anti-tuberculosis treatment were observed, consisting of 31 men, 20 women. Of all patients, there were 26 people with a smoking history, including 25 men and 1 woman. All patients had been recovered, confirmed by clinical state, laboratory and radiology examination. The ELISA test was performed to measure TGF-β level, while chest X-ray was used to evaluate for the occurence of pulmonary fibrosis. Results: The mean level of TGF-β in patients with lesion (+) was 7628.02 pg/mL (SD: ±4928.38) while the mean level of TGF-β in patients with lesion (-) was 2315.11 pg/mL (SD: ±505.83). Statistical test showed a significant relationship between TGF-β level and fibrosis lesion (P
Salat Dhuha Improves Blood Pressure: A Randomized Controlled Trial Boy, Elman; Lelo, Aznan; Tarigan, Amira Permatasari; Machrina, Yetty; Yusni, Yusni; Harahap, Juliandi; Sembiring, Rosita Juwita; Syafril, Santi; Sumartiningsih, Sri
Media Ilmu Keolahragaan Indonesia Vol 11, No 2 (2021): December 2021
Publisher : Universitas Negeri Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/miki.v11i2.34225

Abstract

The prevalence of hypertension increases with age, more than 1 in every two elderly has hypertension, dominated by women. The primary prevention of hypertension is a worldwide public health concern. Salat dhuha is a moderate-intensity physical activity. Salat 2 movement cycles demonstrated improved systolic and diastolic blood pressure in adults. Our study purpose was to assess the effect of 2 and 8 movement cycles (rakaat) of salat dhuha to improve systolic and diastolic blood pressure in healthy Muslim elderly women. Muslim elderly women in a government senior residence (aged 60-74 years) participated in a 6 weeks controlled trial. We completed formal physical, clinical, and blood assessments before admission. Participants with hypertension history were excluded. The participants were randomized into 2 groups. The intervention group performed 8 rakaat of salat dhuha (n=13) and the control group performed 2 rakaat of salat dhuha (n=13). Two participants were dropped out of this study. At baseline and at the end of 6 weeks, a blood pressure examination is recorded. Parametric and nonparametric methods were used to analyze the data. The baseline characteristics of the two groups of participants were homogeneous. Compared to the control, the 8 rakaat of salat dhuha achieved a significant reduction in systolic and diastolic blood pressure (P0.05) at the end of the 6-weeks period. The findings show that salat dhuha has significant potential to improve blood pressure.
Co-Authors Aznan Lelo Christine, Tamara ELMAN BOY Fotarisman Zaluchu, Fotarisman Harahap, Juliandi Nainggolan, Nuryunita Santi Syafril, Santi Sembiring, Rosita Juwita Sri Sumartiningsih Yetty Machrina Yusni Yusni