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Sri Wahdini
Departemen Parasitologi, Fakultas Kedokteran Universitas Indonesia, Jakarta, Indonesia
Medicine & Pharmacology

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Peran Akupunktur dalam Penatalaksanaan Pasien Geriatri Sri Wahdini
eJournal Kedokteran Indonesia Vol. 2, No. 2 (2014): Agustus
Publisher : Faculty of Medicine Universitas Indonesia

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AbstrakPersentase penduduk usia lanjut di Indonesia pada tahun 2012 telah mencapai di atas 7% dari keseluruhan jumlah penduduk. Hal penting terkait peningkatan populasi tersebut adalah perlunya perawatan kesehatan terpadu untuk meningkatkan kapasitas fungsional dan kualitas hidup penduduk usia lanjut. Pasien geriatri adalah pasien usia lanjut yang memiliki karakteristik khusus sehingga membedakannya dari pasien pada umumnya. Kondisi multipatologimengakibatkan seorang usia lanjut mendapatkan berbagai jenis obat dalam jumlah banyak. Terapi non-farmakologi dapat menjadi pilihan untuk mengatasi masalah pada pasien usia lanjut, sehingga dapat mengurangi jumlah obat yang diberikan pada pasien geriatri. Akupunktur sebagai modalitas non farmakologi dapat menjadi pilihan terapi untuk membantu tatalaksana pasien geriatri.Kata kunci: akupunktur, usia lanjut, geriatri, nonfakmakologiAbstractThe percentage of the elderly in 2012 has reached over 7% of the total population in Indonesia. The important thing is related to the increase of these population the need an integrated health care to improve the functional capacity and quality of life. Geriatric patients are elderly patients who have special characteristics that differentiate it from the patient in general. The geriatric patients can get various kinds of drugs in large quantities because of multipatology condition. Non-pharmacological therapy may be an option to overcome the problems in elderly patients, thus reducing the amountof drug administered in geriatric patients. Acupuncture as a non-pharmacological modality therapy can be an option to help geriatric patients.Keywords: acupuncture, elderly, geriatric, non-pharmacology
The Effect of Single-Dose Albendazole on the Prevalence of SoilTransmitted Helminth Infections and Nutritional Status of Children in Perokonda Village, Southwest Sumba Irma Annisa; Reza Damayanti; Dani M. Trianto; Muhammad P. Wiratama; Sri Wahdini; Saleha Sungkar
eJournal Kedokteran Indonesia Vol 5, No 2 (2017): Vol 5, No. 2 (2017): Agustus
Publisher : Faculty of Medicine Universitas Indonesia

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Perokonda Village located in Sumba Island is one of the most underdeveloped regions in Indonesia with high risk of soil-transmitted helminthes (STH) infections. These parasites could affect nutritional status of the subjects. This study was aimed to know the nutritional status and to evaluate the effectiveness of treatment using singledose albendazole on the prevalence of STH infections in Perokonda Village. This study used a pre-post design. Data were collected twice on August 2015 and January 2016. Data of STH infections were obtained from stool samples examined under light microscope. Nutritional status was assessed by determining Z-score in accordance with WHO chart. A total of 66 children were included ranging between 1-12 years old. This study showed that before treatment, subjects with normal nutritional status were 84,8% and 15,2% were underweight. After treatment, subjects with normal nutritional status declined to 75,8%, subjects who were underweight increased to 19,7%, and 4,5% were severely underweight. The result also showed that prevalence of STH was still high after treatment. Prevalence of A.lumbricoides infections significantly decreased (McNemar test, p=0,001), while prevalence of T.trichiura and hookworm infections increased. In conclusion, single dose albendazole significantly reduced the infections of A.lumbricoides, but it did not reduce the prevalence of T.trichiura and hookworm infections. Further study is needed to measure the effectiveness of treatment using triple dose albendazole for STH infection and its association with children’s nutritional status in Perokonda Village.
Effectiveness of Double Dose Mebendazole in Treating Soil-Transmitted Helminths Infections in Perokonda, Southwest Sumba Sri Wahdini; Yusuf Ananda; Saleha Sungkar
eJournal Kedokteran Indonesia Vol 6, No 2 (2018): Vol 6, No. 2 (2018): Agustus
Publisher : Faculty of Medicine Universitas Indonesia

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Treatment of trichuriasis with single dose of albendazole or mebendazole gives low cure rate (CR). The purpose of this study aimed to know the effectiveness of double doses 500 mg mebendazole againts soil transmitted helminths (STH) infection in children aged 2-15 years. This study used a pre post design, conducted on July 2016-February 2017 in Perobatang village, Southwest Sumba. Effectiveness is assessed from CR and egg reduction rate (ERR). Stool samples were examined microscopically with Kato-Katz method. In total of 89 subjects, prevalence of STH, Ascaris lumbricoides and Trichuris trichiura infections were 79.8%, 46.1% and 76.4%. After administration of double dose 500 mg mebendazole the prevalence decresed to 39.3%, 2.2%, 39.3%. CR of A.lumbricoides was 95.1% and T.trichiura was 48.5% while ERR of each infection was 97.98% and 69.73%. There were significant difference in prevalence and ERR before and after treatment (p<0.001). In conclusions double doses 500 mg mebendazole was effective in treating A.lumbricoides but was not for T.trichiura. However, CR and ERR of double dose 500 mg mebendazole againts T.trichiura are higher than single doses.
Detection of Cryptosporidium sp Coproantigen in Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome Patient with Chronic Diarrhea Sri Wahdini; Agnes Kurniawan; Evy Yunihastuti
eJournal Kedokteran Indonesia Vol 4, No 1 (2016): Vol 4, No. 1 (2016): April
Publisher : Faculty of Medicine Universitas Indonesia

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Cryptosporidium sp is one of protozoan that cause diarrhea in immunodeficient patients such as HIV/AIDS. Detection of coproantigen of Cryptosporidium sp is more sensitive than microscopic detection. The objective of this study is to detect cryptosporidiosis using coproantigen detection compare to microscopic detection from stool of HIV/AIDS patients with crhonic diarrhea. A Total of 95 stool specimens from HIV/AIDS patients with chronic diarrhea were received by Laboratorium klinik Parasitologi Faculty of Medicine UI. The stool was tested using coproantigen and microscopy detection for cryptosporidiosis. The frequency of cryptosporidiosis using koproantigen detection was 36.8% while the MTA method was only 11.6%. Sensitivity and specificity of coproantigen detection compared with the microscopic was 100% and 71.4%. Detection coproantigen necessary in patients with high suspicion of cryptosporidiosis but oocysts detection was negative.
The effect of albendazole toward anemia in children with soil-transmitted helminths infection in a remote and endemic area Wahdini, Sri; Kusumowidagdo, Gladys; Gozali, Meutia N.; Tambunan, Fitry B.J.; Sungkar, Saleha
Medical Journal of Indonesia Vol 27, No 4 (2018): December
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (280.611 KB) | DOI: 10.13181/mji.v27i4.2857

Abstract

Background: Soil-transmitted helminths (STH) infections lead to nutritional disorder and anemia among children. Albendazole 400 mg is used to control STH, although it has a low cure rate for Trichuris trichiura. The effectiveness of albendazole could be increased by giving a dose of 400 mg for 3 consecutive days. The aim of the study was to investigate the effectiveness of the triple-dose albendazole 400 mg course in decreasing STH and anemia prevalence.Methods: This study used an experimental comparative design conducted in July 2016 and January 2017 in Perobatang Village, Southwest Sumba, Indonesia. Children aged 1–15 years were asked to collect fecal samples to be examined using a Kato-Katz method. Hemoglobin level (Hb) was tested using a rapid test diagnostic strip. STH positive subjects were given 400 mg of albendazole for 3 days witnessed by the researchers. Six months after, the stool samples and Hb levels were re-examined (post-test).Results: From the 156 subjects examined (pretest), the prevalence of Ascaris lumbricoides, Trichuris trichiura, and hookworm were 65.4%, 55.8%, and 15.4%, respectively, and the prevalence of anemia was 71.2%. On post-test, the prevalence of A. lumbricoides, T. trichiura, and hookworm decreased to 8.3%, 12.8%, and 0%, respectively, and the prevalence of anemia decreased to 25%. There was a significant difference in the prevalence of STH infection and anemia before and after the administration of triple-dose albendazole (p=0.001).Conclusion: The triple-dose albendazole is effective in reducing the prevalence of STH and anemia in children with STH infection.
Co-Authors Agnes Kurniawan Dani M. Trianto Evy Yunihastuti Gozali, Meutia N. Irma Annisa Kusumowidagdo, Gladys Muhammad P. Wiratama Reza Damayanti Saleha Sungkar Saleha Sungkar Saleha Sungkar Tambunan, Fitry B.J. Yusuf Ananda