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Yusuf Nawawi
Department of Public Health and Community Medicine, Faculty of Medicine, Syiah Kuala University, Banda Aceh, Indonesia Radiology Department, Moewardi Hospital, Faculty of Medicine, Sebelas Maret University, Surakarta, Indonesia
Medicine & Pharmacology

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Chest X-ray evaluation of cavitary lesions among pulmonary MDR-TB patients in Kariadi Hospital, Semarang, Indonesia Resta Farits Pradana; Yusuf Nawawi; Bambang Satoto
eJournal Kedokteran Indonesia Vol 6, No 2 (2018): Vol 6, No. 2 (2018): Agustus
Publisher : Faculty of Medicine Universitas Indonesia

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Abstract

The objective of this study is to know the relationship between MDR-TB treatment to the changes in diameter and thickness of cavity wall on chest X-ray (CXR) 6 month and 12 months post treatment. This study was conducted in MDR-TB clinic in Kariadi Hospital, Semarang on January 2013-December 2016. We examine cavitary lesions, evaluated with CXR in pulmonary MDR-TB patients before and after 6 and 12 months of treatment course. Subjects who had been diagnosed as pulmonary MDR-TB and had received MDR-TB treatment for at least 12 months were chosen. Subjects characteristics and cavities features i.e. cavity number, diameter and wall thickness from initial and follow-up CXR 6 and 12 months of treatment were retrieved. A total of 43 patients of MDR-TB, consisted of 22 males and 21 females, was recruited. Most of the subjects aged 31-50 year old and presented with single cavity. The cavitary lesions showed significant reduction over 6 and 12 months of follow up based on CXR (p<0.001) for both diameter and wall thickness. Both diameter and wall thickness changed significantly from initial to 6 months (r=-0.87, p<0.001), initial to 12 months (r=-087, p<0.001), and 6 months to 12 months (r=-0.84, p<0.001), respectively. In conclusion, CXR as a useful diagnostic instrument that can be used to evaluate pulmonary TB, in primarily low resource setting.
Co-Authors Bambang Satoto Resta Farits Pradana