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All Journal Proceedings of Annual International Conference Syiah Kuala University - Life Sciences & Engineering Chapter Medical Laboratory Technology Journal Jurnal Media Analis Kesehatan Jurnal Kesehatan Jurnal Inovasi Kesehatan JURNAL BIDAN CENDRAWASIH PALU
Irfan Idris
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Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Education Engineering Health Professions Immunology & microbiology Library & Information Science Nursing Public Health Other

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Kadar Endotelin -1 Pada Ibu Hamil Trimester Iii Dengan Hipertensi Gestasional Tumani, Yuni Kristiani; Irfan Idris; Fatmawati Madya
Jurnal Bidan Cendrawasih Palu Vol 2 No 1 (2020): Maret
Publisher : Akademi Kebidanan Palu Sulawesi Tengah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47303/jbcp.v2i1.20

Abstract

Hipertensi gestasionalmerupakan penyebab angka kematian ibu (AKI) terbesar kedua di Indonesia, dimana terjadi peningkatan fungsi endotel, yaitu endotelin-1 (ET-1). Tujuan penelitian ini adalah untuk mengetahui kadar ET-1 pada kehamilan normal dan hipertensi gestasional.Sebanyak 40 ibu hamil trimester III yang diambildengan teknik pengambilan sampel Purposive sampel terbagi atas 20 ibu hamil dengan kehamilan normal dan 20 ibu hamil dengan hipertensi gestasional di ambil sampel darahnya sebanyak 3 mL, yang kemudian di bawah ke Laboratorium RSUP Universitas Hasanuddin untuk pemeriksaan kadar ET-1 menggunakan Human Endothelin-1 ELISA Kit. Analisa data menggunakan uji Mann Whitney U, hasil menunjukkan tidak ada perbedaan bermakna antara kadar ET-1 pada ibu hamil trimester III dengan kehamilan normal dan hipertensi gestasional, p=0,372 (p>0,05), dimana kadar ET-1 lebih tinggi pada kehamilan normal.
Kadar Nitrat Okside Pada Ibu Hamil Trimester III Dengan Hipertensi Gestasional Juwita; Irfan Idris; Fatmawati Madya
Jurnal Bidan Cendrawasih Palu Vol 2 No 2 (2020): SEPTEMBER
Publisher : Akademi Kebidanan Palu Sulawesi Tengah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47303/jbcp.v2i2.28

Abstract

Nitric Oxcide is an essential amino acid L-arginine in vascular endothelial cells and mediates relaxation of smooth muscle which causes vaso contraception of capillary vessels, that causes increasing blood pressure and becoming hypertension. This study aims to determine whether the value of Nitric Oxcide levels in hypertension pregnant women is lower or higher than pregnant women without hypertension. The study was conducted at RSIA St. Fatimah Makassar, Jumpandang Baru Health Center and Antang Perumnas Health Center, with the research method using a purposive sampling technique in accordance with the inclusion criteria of trimigravida pregnant women, third trimester pregnant women, diagnosed with gestational hypertension based on the results of the examination and medical record, willing to be a respondent and sign an informed consent. The results showed that the Nitric Oxside level in gestasional hypertension pregnant women (13.31 ng/ml) was higher than the Nitric Oxcide level of pregnant women without gestational hypertension (11.88 ng/ml) and then Mann Whitney test was performed p = 0.787 ( p ≥ 0.05).
Correlation Between Onset of Diabetes Mellitus and Nitric Oxide Levels in Patient with Type 2 Diabetes Mellitus Theosobia Grace Orno; Mansyur Arif; Irfan Idris
Medical Laboratory Technology Journal Vol. 4 No. 1 (2018): June
Publisher : Poltekkes Kemenkes Banjarmasin Jurusan Analis Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (930.985 KB) | DOI: 10.31964/mltj.v4i1.175

Abstract

Type 2 diabetes mellitus (DM) is associated with increased risk of endothelial dysfunction if it lasts a long time without control. This study aims to connect the Onset of Diabetes Mellitus (DM) with Nitric Oxide levels in patients of type 2 diabetes mellitus. The study used cross-sectional study method. The samples were 86 subjects, consisting of 38 subjects of Type 2 DM controlled and 48 subjects of Type 2 DM uncontrolled. The results of the Kruskal-Wallis statistical test showed no significant difference between the Onset of DM and Nitric Oxide levels in the categories of 4-6 years (19.4 ± 10.1), 7-9 years (17.3 ± 9.3) and 10-12 years (13.3 ± 8.5) (p=0.06). Furthermore, the Spearman correlation test revealed a negative correlation between the Onset of DM and Nitric Oxide level in patients with Type 2 DM with and without control (r =-0.217). The level of Nitric Oxide (NO) can consider as a predictor of long-term complication in patients with type 2 DM.
Perbandingan Kadar Endotelin-1 pada Tikus Wistar Obes dan Non Obes Hamil Evi Hudriyah Hukom; Irfan Idris; Wardihan Sinrang
Jurnal Inovasi Kesehatan Vol 1, No 1 (2019): Oktober
Publisher : Sekolah Tinggi Ilmu Kesehatan Papua

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (276.948 KB)

Abstract

Wanita hamil dengan obesitas memiliki resiko lebih besar dalam mengalami preeklampsia dibandingkan dengan yang normal. Tujuan dari penelitian ini adalah membandingkan kadar endotelin-1 antara tikus wistar hamil yang mengalami obesitas dan tikus wistar hamil yang tidak mengalami obesitas. Penelitian ini dilaksanakan di Laboratorium Entomologi Fakultas Kedokteran Universitas Hasanuddin Makassar. Penelitian ini adalah desain kontrol pasca uji. Sampel terdiri atas 11 tikus wistar yang dibagi menjadi 2 kelompok, yaitu 5 sampel dalam kelompok obes dan 6 sampel dalam kelompok nonobes. Data dianalisis dengan menggunakan uji-T tidak berpasangan. Hasil penelitian menunjukkan kadar endotelin-1 pada tikus hamil nonobes lebih rendah (53.37 pg/ml) dibandingkan dengan tikus wistar hamil obes (53.82 pg/ml) namun perbedaannya tidak bermakna (p= 0.937). Kesimpulan penelitian ini yaitu tidak terdapat perbedaan yang bermakna antara tikus wistar hamil obes dengan hamil non obes.
HbA1C levels in adolescent obesity, overweight and normoweight catholic high school eagles in Makassar Rajawali . Hasanuddin; Ilhamjaya Patellongi; Irfan Idris; . Rosdiana
Proceedings of The Annual International Conference, Syiah Kuala University - Life Sciences & Engineering Chapter Vol 1, No 1 (2011): Life Sciences
Publisher : Syiah Kuala University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (82.37 KB)

Abstract

HbA1c Levels In Adolescent Obesity, Overweight and Normoweight Catholic High School Eagles in Makassar. Also known as glycohemoglobin or HbA1c abbreviated as A1c, is one of the important blood tests to evaluate blood sugar control. Obesity is the accumulation of adipose (adipocytes: specific fatty tissue that kept the body) to excess which is the major risk factor for diabetes. This study aims to determine differences in HbA1c levels in adolescent obesity, overweight and normoweight. The research was conducted at Catholic High School Eagles Makassar. The research was conducted with a quantitative approach and the type of study is a cross sectional study. Sampling Purposive sampling as many as 40 people and the data were analyzed with non parametric statistical test of Kruskal-Wallis and Mann-Whitney test. Research results show that there are differences in HbA1c levels in adolescent obesity, overweight and normoweight with p value of 0.007 at significance level p = 0.05. While based on Abdominal Circumference (LP) to the category of central obesity and non-obese as well there is a difference with a p value of 0.041 at significance level p = 0.05.
HUBUNGAN ANTARA NILAI HEMATOKRIT DENGAN TROMBOSIT TERHADAP HASIL PEMERIKSAAN NS1 DAN SEROLOGI IgM DAN IgG PADA PASIEN DEMAM BERDARAH DENGUE NURDIN ALI; Uleng Bahrun; Irfan Idris
Jurnal Media Analis Kesehatan Vol 8, No 2 (2017): JURNAL MEDIA ANALIS KESEHATAN
Publisher : Poltekkes Kemenkes Pakassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (368.337 KB) | DOI: 10.32382/mak.v8i2.838

Abstract

Demam berdarah dengue  adalah penyakit yang ditandai dengan demam dan perdarahan. Penelitian ini bertujuan untuk mengetahui  hubungan nilai hematokrit dan trombosit terhadap hasil pemeriksaan NS1  dan serologi (DHF IgM IgG). Desain penelitian adalah cross sectional dengan jumlah sampel 61 pasien  yang memenuhi kriteria inklusi. Analisis data secara deskriptif dan Analisis multivariat digunakan untuk melihat korelasi antara trombosit dengan hematokrit terhadap 3 kelompok hasil pemeriksaan. Hasil penelitian terdiri dari perempuan sebanyak 26 (42,6%) dan laki-laki sebanyak 35 (57,4 %) dengan usia termuda 11 bulan dan tertua 71 tahun, yang terbanyak umur antara range 11-20 tahun 18 orang (29,5%), Trombositopenia (<150.000/ɥL) sebanyak 33 sampel (50,7%) dengan rerata±S.D yaitu 151.016, 4 ± 90.352,9. Nilai Hematokrit juga mengalami penurunan dari nilai normal (laki-laki : 40-54 % ; perempuan : 38-47%) sebanyak 25 sampel (41,0%) dengan rerata ± S.D yaitu 39,2 ± 4,2 (p<0,016). Untuk laki-laki nilai rerata hemaokrit diperoleh 39,9 ± 4,7 sedangkan perempuan ditemukan 38,2 ± 3,2. Penelitian ini tidak ditemukan hemokosentrasi atau peningkatan nilai hematokrit ≥ 20 %. Analisis multivariat uji korelasi pearson (p > 0,04) antara hematokrit dengan trombosit pada penderita DBD. Uji korelasi antara hematokrit dengan trombosit terhadap hasil pemeriksaan NS1 positif (p<0,018). Sedangkan hubungan antara hematokrit dengan trombosit pada masing-masing hasil pemeriksaan DHF IgM positif ada korelasi antara nilai trombosit dengan hematokrit pada ketiga kelompok (NS1 positif, DHF IgM positif IgG negatif, DHF IgM positif IgG positif) dan korelasi terjadi juga antara nilai trombosit dengan hematokrit pada hasil pemeriksaan NS1 positif. Sedangkan uji korelasi antara nilai hematokrit dengan trombosit pada DHF IgM positif IgG negatif, DHF IgM positif IgG positif tidak ditemukan korelasi yang bermakna. Kata kunci : Hematokrit, Trombosit, pemeriksaan NS1 dan serologi, DBD
Perbandingan Otago, Basic Exercise, dan Kombinasi Keduanya Terhadap Kekuatan Otot dan Fungsional Berjalan Penderita Osteoarthritis Dian Ambarwaty Prasetyo; Andi Ariyandy; Irfan Idris
Jurnal Kesehatan Vol 10 No 1 (2022): April
Publisher : Politeknik Negeri Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25047/jkes.v10i1.316

Abstract

Osteoarthritis (OA) is the most common joint disease that reduces quality of life. It’s often associated with impaired mobility due to pain and muscle weakness, thus being a risk factor for falls down. This study aimed to compare the effect of otago exercise, basic exercise, and a combinations of the two on changes in muscle strenght and functional ability to walk in patients with knee OA. This study was a comparative analytic study with 60 participants divided into three treatments. There were a total of 20 paticipants in each treatment. Repeated ANOVA was used as a statistical test with significancy p ≤ 0,05. The result, there was a significant difference between the three treatment groups in term of changes in muscle strength (p=0.003) and functional ability to wal (p=0.036). Post hoc results showed that the combined otago exercise and basic exercise group had a significantly difference in muscle strength and fungsional ability to walk than the otago exercise and basic exercise group. This study concludes that combining otago exercise and basic exercise is more efective than otago exercise or basic exercise only in increasing muscle strenght and functional ability to walk.
Co-Authors . Hasanuddin . Rosdiana Andi Ariyandy Dian Ambarwaty Prasetyo Evi Hudriyah Hukom Fatmawati Madya Ilhamjaya Patellongi Juwita Mansyur Arif Nurdin Nurdin Theosobia Grace Orno Uleng Bahrun Wardihan Sinrang Yuni Kristiani Tumani