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Karsinoma Nasofaring dengan Multiple Cranial Nerve Palsy Pada Pasien Wanita Usia 52 Tahun Arilinia Pratiwi; Mukhlis Imanto
Medula Vol 9 No 4 (2020): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v9i4.223


Nasopharyngeal Carcinoma is a malignant disease that appears in the nasopharyngeal area, namely the area above the throat and behind the nose. Nasopharyngeal carcinoma is an example of malignancy in the THT-KL and is the 4th most common malignancy case after breast cancer, cervical cancer, and lung cancer in Indonesia. The etiology of nasopharyngeal carcinoma is multifactorial, namely infection from Epstein Barr virus, genetic, and related to the environment such as consumption of salted fish, smoking habits, food preservatives, mosquito coils, and wood smoke. This case was found in a female patient, 52 years old, who came to Dr. Hospital. H. Abdoel Moeloek with complaints of headache since 2 months ago. Other complaints felt by patients are double vision, ringing in the ears, face feels numb on one side, pelo talk and tongue falling to one side, and nausea and weakness. There was a complaint of a lump appearing on the right neck since 5 months ago before complaints of headache appeared. The results of physical and supporting examinations and biopsy examinations have been carried out and the results obtained refer to the diagnosis of nasopharyngeal carcinoma. Treatment carried out on patients is symptomatic to reduce symptoms and is referred to a higher hospital for further treatment.
Peningkatan Pengetahuan Siswa SMKN 2 Bandar Lampung Tentang Bahaya Rokok Melalui Penyuluhan Nisrina Aulia Amirah; Dyah Wulan Sumekar; Tri Umiana Soleha; Mukhlis Imanto
Medula Vol 10 No 2 (2020): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v10i2.65


Smoking is a global health problem, almost every country experiences an increase in adolescent smokers. Indonesia is the third largest country with the highest number of smokers after China and India. Various methods have been used to reduce the number of smokers at an adolescent. One effective method of preventing an increase in the number of adolescent smokers is counseling about cigarette risk knowledge. In preliminary research, we got there are around 90% of smoking students especially male students. The cause is lack adolescent knowledge against the dangers of smoking. This research aims to know the effect of counseling on cigarette risk knowledge in student SMKN 2 Bandar Lampung. It was carried out in April 2017, place in SMKN 2 Bandar Lampung. The results of the hypothesis with the values of the t-test paired obtained p = 0000 that indicate a difference of knowledge comparison before and after counseling on Students of SMKN 2 Bandar Lampung. So it can be inferred that the counseling intervention can increase cigarette risk knowledge on students SMKN 2 Bandar Lampung.
Pengaruh Pemberian Ekstrak Etanol Rimpang Lengkuas (Alpinia galangal L.Willd) Terhadap Gambaran Histopatologi Ginjal Mencit Jantan (Mus musculus L.) yang Diinduksi oleh Monosodium Glutamat (MSG) Muhartono Muhartono; Mukhlis Imanto; Nadia Rosmalia Dewi
Jurnal Kedokteran Universitas Lampung Vol 2, No 1 (2018): JK UNILA
Publisher : Fakultas Kedokteran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23960/jk unila.v2i1.1909


Monosodium Glutamat (MSG) adalah garam natrium glutamat yang digunakan sebagai penambah rasa. Menurut Riset Kesehatan Dasar tahun 2013 sekitar 77,3%. MSG dikonsumsi masyarakat Indonesia. MSG dapat membentuk radikal bebas sehingga menyebabkan kerusakan organ-organ tubuh salah satunya organ ginjal manusia. Rimpang lengkuas adalah salah satu bahan alami yang mengandung antioksidan yang dapat mecegah kerusakan organ akibat radikal bebas. Tujuan daripenelitian ini adalah untuk mengetahui pengaruh pemberian ekstrak etanol rimpang lengkuas terhadap gambaran histopatolgi ginjal mencit yang diinduksi MSG. Desain penelitian ini adalah eksperimental dengan 5 kelompok perlakuan, tiap kelompok terdiri dari 5 ekor mencit (Mus Musculus L.) strain DDY. Kelompok K(-) (kontrol -) tidak diberi perlakuan; kelompok K+(kontrol +) diberikan MSG 4mg/grBB; kelompok P1 (perlakuan 1) diberikan MSG 4mg/kgBB + ekstrrak etanol rimpang lengkuas 14mg/20grBB; kelompok P2 (perlakuan 2) diberikan MSG 4mg/kgBB + ekstrrak etanol rimpang lengkuas 28mg/20grBB; kelompok P3 (perlakuan 3) diberikan MSG 4mg/kgBB + ekstrrak etanol rimpang lengkuas 56mg/20grBB. Berdasarkan hasil uji statistik One Way ANOVA didapatakan hasil yang bermakna dan dilanjutkan dengan uji Post Hoc. Pada uji Post Hoc terlihat adanya pengaruh perlakuan terhadap penurunann degenerasi sel ginjal yang bermakna secara statistikterhadap peningkatan dosis ekstrak etanol rimpang lengkuas. Terdapat pengaruh pemberian ekstrak etanol rimpang lengkuas terhadap gambaran histopatologi ginjal mencit yang diinduksi MSG.Kata kunci: Ekstrak lengkuas, histopatologi ginjal, monosodium glutamat
Medula Vol 11 No 1 (2021): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v11i1.254


Nutrition plays an important role in children health. The prevalence of underweight children in Indonesia by 11.2% to 4.0% was very thin and emaciated 7.2%, while the obese children by 18.8%, consisting of 10.8% obese children and obese amounted to 8.8%. Lampung Province was ranked second among the provinces with a skinny kid. The nutritional status itself can be affected by several things, one of which is the status of demographics. The purpose of this study is known association of sociodemographic factors with nutritional status of children. This type of research is an analytic observational with cross sectional approach. The population is students of SDN 1 South Pringsewu, with a sample size of 225 people. The statistical test used was chi - square. The results of the univariate analysis are mostly had normal nutritional status (68%), age 6-9 years (75.6%), female (51.1%), highly educated mothers (77.3%), father's occupation were self-employed (64%), parents have a high income levels (> Rp. 1.581 million) (69.3%). The results of the bivariate analysis obtained no relationship between maternal education level (p-value < 0.001), the type of father's occupation (p-value < 0.001), and the level of family income (p-value < 0.001) with the nutritional status of children. While there is no correlation between age (p-value = 0.829), and the child's gender (p-value = 0.307) with the nutritional status of children. Expected the school to coordinate with health officials in monitoring the nutritional status of their students. Keywords : Sociodemographic, nutritional status of children
Kolaborasi Tuberculosis (TBC) dan Human Immunodeficiency Virus (HIV) Yona Arisena Magdalena Silitonga; Intanri Kurniati; Retno Ariza; Mukhlis Imanto; Jhond Fatriyadi S
Medula Vol 9 No 2 (2019): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v9i2.269


Tuberculosis (TBC) is becoming one of the highest causes of death in the world. Tuberculosis is caused by Mycobacterium tuberculosis that is transmitted via droplet originating from tuberculosis patients. It is estimated that one-third of people in the world have been infected by tuberculosis, but only 10-20% of people will show the symptoms. Symptoms that can arise in tuberculosis are such as bleeding cough, weight loss, night sweats, chest pain, shortness of breath and weakness. Meanwhile, human immunodeficiency virus (HIV) is a retrovirus-famili because of its ability to convert the RNA genome into DNA. HIV transmission occurs due to the entry of this virus into the body through body fluids of people who are already infected by HIV. Both of these infectious diseases alike because both of them can cause a decrease in immune system activities in the body of the sufferer. Collaboration of both diseases is common and is a deadly combination because it interacts with each other in all aspects of the disease, ranging from pathogenesis, epidemiology, clinical manifestations, treatment and prevention. Tuberculosis is also a leading cause of death in HIV-positive patients. In 2016 in Indonesia, there are found 360,565 cases of TBC, with 14% of them are also known to suffer from HIV-positive. The results of the study suggest that there is a mutual relationship between the two diseases in causing a clinical symptoms through decreased activity of the body's immune system.
Peningkatan Pengetahuan Terhadap Gangguan Kesehatan Mata, Telinga Hidung Dan Saluran Pernafasan Yang Berhubungan Dengan Kasus Agromedicine Rani Himayani; Helmi Ismunandar; Mukhlis Imanto; Rasmi Zakiah Oktarlina; Ari Wahyuni
Prosiding Konferensi Nasional Pengabdian Kepada Masyarakat dan Corporate Social Responsibility (PKM-CSR) Vol 3 (2020): Peran Perguruan Tinggi dan Dunia Usaha Dalam Pemberdayaan Masyarakat Untuk Menyongsong
Publisher : Asosiasi Sinergi Pengabdi dan Pemberdaya Indonesia (ASPPI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (2770.654 KB) | DOI: 10.37695/pkmcsr.v3i0.953


Latar Belakang: Indonesia merupakan negara dengan keanekaragaman hayati dan ekosistem pertanian dan perkebunan. Pekerja yang berada di sektor agrikultur seperti petani atau pekerja diperkebunan, ditemukan beberapa penyakit akibat kerja. Namun, rasio penyakit akibat kerja jauh lebih sulit untuk diukur, karena penyakit pribadi yang dimiliki oleh petani sulit diidentifikasi sebagai penyakit yang berhubungan dengan pekerjaannya. Penyakit akibat kerja cenderung sulit untuk ditegakkan karena terkadang saling tumpang tindih dengan penyakit lain di luar pekerjaan yang diderita oleh pekerja. Tujuan: Peningkatan pengetahuan masyarakat tentang gangguan kesehatan mata, telinga hidung dan saluran pernafasan yang berhubungan dengan kasus agromedicine pada komunitas keluarga dan pekerja di PTPN VII Way Berulu Kabupaten Pesawaran Lampung, sehingga penyakit karena pekerjaan dapat di cegah terutama saat usia produktif dan dilakukan deteksi dini untuk membantu skreening awal penyakit dilingkungan kerja di masyarakat terutama di PTPN VII Way Berulu Kabupaten Pesawaran. Metode : Metode penyuluhan masyarakat dan deteksi dini kesehatan mata, telinga hidung dan saluran pernafasan di PTPN VII Way Berulu. Hasil : Kegiatan diikuti oleh total 40 orang pekerja PTPN VII Way Berulu yang dipilih untuk menghadiri penyuluhan. Berdasarkan data hasil pengamatan pre-test, diketahui sekitar 57% peserta tidak paham mengenai pengetahuan kelainan mata merah/tukak kornea, gangguan pernafasan, rhinitis. Setelah dilakukan kegiatan penyuluhan, nilai hasil pengamatan meningkat. Sebagian besar peserta menjadi paham.
Hubungan Pekerjaan Terhadap Katarak Wildan Kautsar Irawan; Rani Himayani; Mukhlis Imanto; Ety Apriliana; Muhammad Yusran
Jurnal Medika Hutama Vol. 3 No. 04 Juli (2022): Jurnal Medika Hutama
Publisher : Yayasan Pendidikan Medika Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar


Katarak adalah penyakit yang merupakan penyebab utama kebutaan di dunia. Penyakit ini merupakan penyakit multifaktorial yang memiliki dampak yang besar terhadap produktivitas seseorang. Angkatan kerja di Indonesia mencapa 140,15 juta orang dengan pertanian, kehutanan, dan perikanan menjadi lapangan usaha yang menyerap tenaga kerja paling banyak. Artikel ini bertujuan untuk mengetahui apakah ada hubungan antara pekerjaan dengan katarak menggunakan metode tinjauan pustaka (literature review). Didapatkan hasil berupa penelitian penelitian yang dilakukan di Indonesia menunjukkan adanya hubungan antara pekerjaan dengan katarak. Dari beberapa penelitian, disimpulkan bahwa pekerja luar ruangan memiliki kecenderungan lebih besar untuk terkena katarak dan memiliki maturitas lebih tinggi dibandingkan pekerja dalam ruangan.
Faktor Risiko Kejadian Rinitis Alergi pada Anak Intan Nurhaliza Nurhaliza; Mukhlis Imanto
Medula Vol 13 No 1 (2023): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v13i1.540


Allergic rhinitis is one of the global health problems that affect about 400 million people in the world with prevalence of 8.38% in children and 14.93% in adolescents, in Indonesia the incidence of allergic rhinitis reaches 38%. Allergic rhinitis is a clinical symptom that occurs when the nasal mucous membrane is exposed to an allergen and induces an immune system-mediated inflammatory response. Allergic rhinitis can be triggered by several factors, including individual and environmental factors that can lead to resensitization and disease progression. The main risk factor for allergic rhinitis is family history of atopy, especially history of allergic rhinitis in both parents. The presence of atopic dermatitis, asthma, exposure to vehicle acids, cigarettes and house dust, obesity can be factors that increase the risk of allergic rhinitis in children. These risk factors have their respective mechanisms in increasing the risk of allergic rhinitis and have different levels of risk. Other factors such as gender and age did not contribute to increasing the risk of allergic rhinitis in children.
Hubungan Rinitis Alergi dengan Kejadian Asma Bronkial Dinni Istiqomah; Mukhlis Imanto
Medula Vol 13 No 1 (2023): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v13i1.611


Allergic rhinitis is a risk factor for asthma.  The development of asthma is generally more common in patients with allergic rhinitis.  This is in accordance with epidemiological data which states that there has been an increase in cases of allergic rhinitis accompanied by asthma globally.  Allergic rhinitis and asthma are both mediated by Immunoglobulin E (IgE).  The correlation between nasal airflow obstruction in allergic rhinitis sufferers and lung airflow obstruction due to the inflammatory process that occurs in the nasal mucosa of allergic rhinitis and asthma sufferers can be determined by observing the nasal airflow and bronchial airflow.  The diagnosis of asthma can be known by measuring the Forced Expiratory Volume in One Second Percent (FEV1%) value.  In allergic rhinitis patients, a decrease in FEV1% was found and reversibility was found after a bronchodilator test.  Such reversibility is associated with long duration (chronic) allergic rhinitis and early bronchial airflow limitation.  This 1% decrease in FEV and reversibility suggest the presence of BHR, especially in persistent and moderate-severe allergic rhinitis patients.  Duration and type of sensitization (allergen) were identified as early prognostic markers of BHR involvement in allergic rhinitis patients.  Knowing the FEV1% value in allergic rhinitis sufferers is expected to be a preventive measure for the occurrence of asthma.