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All Journal Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Medula Juke Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya Kesmas Indonesia: Jurnal Ilmiah Kesehatan Masyarakat Jambura Journal of Health Sciences and Research Jurnal Kesehatan JURNAL PENELITIAN PERAWAT PROFESIONAL JIMKI : Jurnal Ilmiah Mahasiswa Kedokteran Indonesia JK Unila (Jurnal Kedokteran Universitas Lampung) Poltekita: Jurnal Pengabdian Masyarakat Jurnal Abdimas ADPI Sains dan Teknologi Majority
Dwi Indria Anggraini
Universitas Lampung
Agriculture, Biological Sciences & Forestry Astronomy Biochemistry, Genetics & Molecular Biology Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Education Electrical & Electronics Engineering Energy Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Veterinary

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HUBUNGAN FAKTOR RISIKO DERMATITIS KONTAK PADA PETANI Rahmatika, Achisna; Saftarina, Fitria; Anggraini, Dwi Indria; Mayasari, Diana
Jurnal Kesehatan Vol 11, No 1 (2020): Jurnal Kesehatan
Publisher : Politeknik Kesehatan Tanjung Karang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (167.015 KB) | DOI: 10.26630/jk.v11i1.1465

Abstract

About 30% of occupational diseases in farmers are contact dermatitis. Contact dermatitis due to work in the agricultural sector is the main commodity in Lampung Province at 35,82%. Farmers are generally always exposed to chemicals in the form of pesticides and fertilizers which can be irritants and allergens. This research was an observational descriptive using a cross-sectional method with 379 respondents. The research data were taken from interviews, questionnaires, and physical examinations by dermatologists and genitals. Data were analyzed using the chi-square test. Results: 13,5% of farmers experienced contact dermatitis. The analysis results of this study indicate that there is a statistical relationship between contact dermatitis with the use of the following factors, personal protective equipment (p-value=0,000), contact time (p-value=0,000), personal hygiene (p-value=0,000), total types of pesticides (p-value=0,000), and number of types of fertilizer (p-value=0,000). While the factors that were not statistically significant in this study were the relationship between contact dermatitis and length of service (p-value=0,919), atopic history (p-value=0,784), and type of occupation (p-value=0,115). There is a relationship between the following factors such as the use of personal protective equipment, duration of contact, personal hygiene, the number of pesticides, and the number of types of fertilizers with the incidence of contact dermatitis in farmers in the District of Punduh pedada.
Tatalaksana Terkini Acne Vulgaris Sibero, Hendra Tarigan; Putra, I Wayan Ardana; Anggraini, Dwi Indria
Jurnal Kedokteran Universitas Lampung Vol 3, No 2 (2019): JK Unila
Publisher : Fakultas Kedokteran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23960/jk unila.v3i2.2520

Abstract

Akne vulgaris (AV) termasuk penyakit yang dapat sembuh sendiri (self-limited disease). Penyakit ini dapat ditemukan di segala usia. Yang merupakan peradangan kronik dari unit folikel pilosebasea. Penyebabnya multifaktor dengan gambaran klinis berupa komedo, papul, pustul, nodus dan kista. Penyebab pasti AV masih belum diketahui, namun telah dikemukakan beberapa etiologi yang diduga turut berperan terdiri atas faktor intrinsik yaitu diperkirakan produksi sebum yang meningkat, hiperkeratinisasi folikel rambut, koloni bakteri propionibacterium (P. Acne ), dan inflamsi serta faktor ekstrinsik yaitu stres, iklim/suhu/kelembaban, kosmetik, diet dan obat-obatan. Oleh karena itu artikel ini bertujuan untuk memaparkan tatalaksana terkini dari acne vulgaris. Tatalaksana terkini dan tatalaksana terdahulu dari acne vulgaris tidak jauh berbeda, Pengobatan terkini sangat dianjurkan mengingat kemajuan teknologi dapat mempercepat penyembuhan acne dan meminimalisir gejala sisa dari acne vulgaris.Kata Kunci : Akne Vulgaris, tatalaksana akne
Efek Protektif Jahe Putih Besar (Zingiber Officinale Rosc. Var. Officinarum) terhadap Ulkus Gaster Tikus Jantan Galur Sprague dawley yang Diinduksi Piroksikam Hanriko, Rizki; Anggraini, Dwi Indria; Pairul, Piesta Prima Beta
Jurnal Kedokteran Universitas Lampung Vol 2, No 2 (2018): Jk Unila
Publisher : Fakultas Kedokteran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23960/jk unila.v2i2.1947

Abstract

Tujuan dari penelitian ini adalah mengetahui Efek Protektif Jahe Putih Besar (Zingiber Officinale Rosc. Var. Officinarum) terhadap Ulkus Gaster yang diinduksi oleh Piroksikam. Penelitian ini merupakan penelitian eksperimental metode acak terkontrol dengan pola post only design. 28 ekor tikus putih (Rattus Novergicus) jantan galur Sprague Dawley berumur 10-16 minggu yang dipilih secara acak dan dibagi menjadi 6 kelompok. Kelompok 1 diberikan piroksikam 40mg/200gBB, kelompok 2-5 diberikan Jahe Putih Besar dengan dosis bertingkat yaitu 40mg/200gBB, 80mg/200gBB, 120mg/200gBB dan 160mg/200gBB serta kelompok 6 diberikan Omeprazole 25,2 mg/200gBB. Persentasi penghambatan Ulkus Gaster terbesar hingga terkecil adalah Jahe Putih Besar 160mg/200gBB (77,5%), Jahe Putih Besar 120mg/200gBB (72%), Jahe Putih Besar 80mg/200gBB dan Omeprazole (58%), Jahe Putih Besar 40mg/200gBB (40%). Pada penelitian ini didapatkan hasil bila Jahe Putih Besar 80mg/200gBB dan Omeprazole memiliki efek protektif yang sebanding. Dapat disimpulkan Jahe memiliki efek protektif terhadap ulkus lambung. Kata kunci :Efek protektif, Jahe, Ulkus
Psoriasis Pustulosa Generalisata: Tinjauan Kasus Pada Geriatri Febe Sintia Kristiani; Dwi Indria Anggraini
Medula Vol 9 No 4 (2020): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v9i4.236

Abstract

Psoriasis is a chronic disease of the skin that is characterized by accelerated epidermal exchange and a faster keratinization process. Psoriasis has a variety of manifestations, one of which is generalized pustular psoriasis characterized as pustular sterile eruption. This case report aims to determine the diagnosis and management of generalized pustular psoriasis. Case, a 75-year-old woman complained of the emergence of pustule throughout the body since four days ago accompanied by burning and itching sensation. Some pustule confluence make a lake form (lake of pus), and some lesion consist of erythematous plaque with yellowish greasy scale. The patient has a history of hypertension, use of pain killer, and sudden stopping steroids. Based on history taking, physical examination and laboratory, the diagnosis of generalized pustular psoriasis is made. The treatment given was in the form of corticosteroid methylprednisolone intravenous injection 31,25 mg/ 12 hours, ranitidine intravenous injection 50 mg/12 hours, cetirizine peroral 1x10 mg, betametason valerate cream 0.1% in urea 10% cream.
Hubungan Persepsi Pasien terhadap Peresepan Elektronik dengan Kepuasan Pasien di Instalasi Farmasi Rumah Sakit Imanuel Bandar Lampung Oktarlina, Rasmi Zakiah; Anggraini, Dwi Indria; Carolia, Novita; Zetira, Zihan
Jurnal Kedokteran Universitas Lampung Vol 3, No 1 (2019): JK Unila
Publisher : Fakultas Kedokteran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23960/jk unila.v3i1.2199

Abstract

Rumah Sakit Imanuel Bandar Lampung merupakan rumah sakit yang telah menggunakan sistem peresepan elektronik. Penelitian tentang manfaat dan kelemahan peresepan elektronik sudah banyak dilakukan, namun persepsi pasien tentang peresepan elektronik masih jarang dilakukan. Persepsi pasien perlu diketahui untuk mengetahui kualitas pemberian pelayanan kesehatan yang menggunakan sistem peresepan elektronik. Tujuan pada penelitian ini adalah untuk mengetahui hubungan persepsi pasien terhadap peresepan elektronik dengan kepuasan pasien di Instalasi Farmasi Rumah Sakit Imanuel Bandar Lampung. Metode penelitian ini adalah cross-sectional dengan rancangan studi deskriptif, melibatkan 190 responden yang dilaksanakan pada bulan Agustus sampai Desember 2018, di Instalasi Farmasi Rumah Sakit Imanuel Bandar Lampung. Data penelitian didapatkan melalui pengisian kuesioner yang telah diuji validitas dan reliabilitas. Analisis data yang digunakan adalah uji Fisher’s Exact Test. Hasil analisis data pada penelitian ini mendapatkan hasil p-value 0,031. Kesimpulan yang didapatkan bahwa terdapat hubungan antara persepsi pasien terhadap peresepan elektronik dengan kepuasan pasien di Instalasi Farmasi Rumah Sakit Imanuel Bandar Lampung. Kata kunci: instalasi farmasi, kepuasan, persepsi, resep elektronik
OCCUPATIONAL HEALTH SERVICE & EDUCATION FOR TAPIS CRAFTMAN IN NEGERI KATON VILLAGE Saftarina, Fitria; Isti Angraini, Dian; Indria Anggraini, Dwi; Karimah, Nisa
Jurnal Abdimas ADPI Sains dan Teknologi Vol. 2 No. 2 (2021): Jurnal Abdimas ADPI Sains dan Teknologi
Publisher : Asosiasi Dosen PKM Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47841/saintek.v2i2.212

Abstract

Informal sector workers are workers who are most vulnerable to various risks that cause health problems. Health and safety issues related to their work can interfere with their productivity. Tapis craftsmen in the Negeri Katon Village,Pesawaran Regency, Lampung is part of the Tapis Jejama UMKM. Based on interviews with the UMKM coordinator, it was found that the craftsmen complained of back, neck, arm, and hand pain and symptoms of anemia. This interferes with the productivity of Tapis craftsmen. This service aims to improve the occupational health status of filter craftsmen in Negeri Katon Village to support work productivity in both health and economic aspects. The benefits of this activity are to reduce the incidence of anemia, musculoskeletal pain and help strengthen Negeri Katon Village as a Creative Tourism Village. The activity was carried out with a target of 30 tapis craftsmen. The solutions offered are occupational health services for tapis craftsmen, health education about ergonomics, occupational nutrition, and the stretching benefits. The results obtained that 100% of workers complained of musculoskeletal pain, as many as 5 people (8.3%) got hypertension and as many as 12 people (40%) got anemia. Before education, the knowledge of filter craftsmen about health risks in their work was 68% and after education is carried out, there is an increase of 97%. This activity needs to be carried out with the establishment of the Pos Upaya Kesehatan Kerja (UKK) as an effort to maintain the health of tapis craftsmen in Negeri Katon Village, Pesawaran Regency, Lampung.
Tatalaksana Dermatomikosis pada Pasien Morbus Hansen dengan Reaksi Reversal Dwi Indria Anggraini
JUKE Unila Vol 5, No 9 (2015)
Publisher : Fakultas Kedokteran Universitas Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (166.455 KB)

Abstract

Penggunaan steroid jangka panjang pada pasien morbus Hansen dengan reaksi reversal dapat menimbulkan penekanan sistem imun sehingga lebih mudah mencetuskan dermatomikosis superfisialis. Terdapat berbagai pilihan terapi dermatomikosis. Perlu tatalaksana yang tepat pada pasien dengan reaksi reversal yang menderita infeksi jamur agar morbiditas cepat teratasi. Laporan kasus ini menunjukkan keberhasilan terapi dermatomikosis luas pada pasien Morbus Hansen dengan reaksi reversal. Pasien laki-laki berusia 36 tahun dengan bercak merah yang makin meluas dan terasa gatal terutama saat berkeringat atau panas  di kedua lipat paha dan bawah pusar sejak dua bulan yang lalu. Timbul juga keluhan bercak putih, bersisik, tidak baal di kedua lengan dan punggung sejak 1 bulan yang lalu. Pasien sudah berhenti dari terapi morbus Hansen sejak sekitar dua tahun lalu. Berdasarkan anamnesis, pemeriksaan fisik, dan penunjang ditegakkan diagnosis tinea fasialis, korporis, et kruris, pitiriasis versikolor, dan morbus Hansen tipe borderline lepromatosa release from treatment dengan reaksi reversal. Terapi yang diberikan selama dua minggu berupa terbinafin tablet 250 mg/hari dan sampo ketokonazol 2% dioleskan ke seluruh tubuh kecuali wajah dan genitalia 1 kali per hari selama 10 menit sebelum mandi. Selain itu, tatalaksana linen infeksius dan menjaga higiene. Hasil evaluasi dua minggu pasca terapi, pasien dinyatakan sembuh berdasarkan klinis dan laboratoris. [JuKe Unila 2015; 5(9):48-53]
Hubungan Kejadian Pedikulosis Kapitis dengan Karakteristik Rambut, Tipe Rambut serta Frekuensi Keramas pada Santriwati Pesantren Al-Hikmah, Bandar Lampung Emantis Rosa; Amira Zhafira; Muhammad Yusran; Dwi Indria Anggraini
Kesmas Indonesia Vol 13 No 2 (2021): Jurnal Kesmas Indonesia
Publisher : Jurusan Kesehatan Masyarakat dan Fakultas Ilmu-Ilmu Kesehatan Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.ki.2021.13.2.4182

Abstract

Infeksi pada rambut dan kulit kepala yang disebabkan Pediculus humanus var. Capitis disebut dengan Pedikulosis. Pedikulosis sering ditemukan pada anak-anak usia sekolah khususnya di tempat yang sering dipakai bersamaan seperti di asrama, pesantren dan lain sebagainya. Ada beberapa faktor yang mempengaruhi jumlah kasus pedikulosis antara lain karakteristik rambut, tipe rambut dan kebersihan rambut atau frekuensi keramas. Tujuan dari penelitian ini untuk mengetahui hubungan kejadian Pedikuolosis kapitis dengan karakteristik rambut, tipe rambut serta frekuensi keramas pada santriwati di Pesantren Al-Hikmah, Bandar Lampung. Hasil penelitian menunjukkan terdapat hubungan yang bermakna antara kasus pedikulosis kapitis dengan panjang rambut denga nilai sebesar (p =0,026). Namun tidak terdapat hubungan yang bermakna antara kasus pedikulosis dengan tipe rambut dan frekuensi keramas dengan nilai p masing-masing sebesar (p= 0,388) dan (p=0,620). Kata Kunci: pedikulosis kapitis, tipe rambut, karakteristik rambut, frekuensi keramas
The influence of acetylation status of tuberculosis patients on the isoniazid serum concentrations and sputum conversion after intensive phase therapy Dwi Indria Anggraini; Erna Kristin; iwan Dwiprahasto
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 50, No 1 (2018)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (429.047 KB) | DOI: 10.19106/JMedSci005001201807

Abstract

Isoniazid (INH), one of the major antituberculosis drugs, is metabolized by acetylation. Previously study proved the significant differences of serum INH concentration between subject with fast and slow acetylation status. However, the correlation of acetylation status with treatment outcome after fixed-dose combination antituberculosis therapy (FDC-ATT) was not explained. The aim of this study was to evaluate the influence of acetylation status on the treatment outcome and the serum INH concentrations in the adult tuberculosis patients underwent FDC-ATT. A cross sectional study was carried out on 31 tuberculosis patients. Acetylation status was measured by spectrophotometer and serum INH concentration was measured by high performance liquid chromatography (HPLC). Sputum conversion assay was conducted by Ziehl Nelsen method. t-Test, chi square, Mann-Whitney, and Fisherman were used to analyze the data. The proportion of the fast acetylator was 61.3%, whereas the slow acetylator was 38.7%. The proportion of success and failure sputum conversion were 83.9% and 16.1%, respectively. The mean serum INH concentration in the fast acetylator groups (1.52 ± 0.15 μg/mL) was significantly lower than that in the slow acetylator groups (3.84 ± 0.35 μg/mL). The failure conversion risk of the fast acetylator group was about two folds higher than the slow acetylator group, although it was not significantly different (RR=2.53; 95% CI=0.32-20.00; p>0.05). Moreover, the mean serum INH concentration in success (2.46 ± 0.31 μg/mL) and failure (1.89 ± 0.20 μg/mL) sputum conversion was not significantly different (p>0.05). In conclusion, the acetylation status does not influence the sputum conversion in adult tuberculosis patients after FDC-ATT although the serum INH concentration on slow acetylation status is higher than that fast acetylation status. 
The effect of the implementation of evidence-based drug formulary on antibacterial use in a private hospital at Tanjung Enim, Sumatera Selatan, Indonesia Erna Kristin; Dwi Indria Anggraini; Jarir At Thobari; Alfi Yasmina
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 49, No 1 (2017)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (255.17 KB) | DOI: 10.19106/JMedSci004901201703

Abstract

The increase of drug expenditure in the hospital has facilitated the implementation of an evidence-based drug formulary. The aim of this study was to assess the change in antibacterial use after the implementation of an evidence-based drug formulary in a private hospital at Tanjung Enim, Sumatera Selatan, Indonesia. This study used a pre-posttest design. Drug use data in the period before (2010-2011) and after (2012-2013) the formulary implementation were extracted from the hospital medical records. The drug use in the hospital before and after the implementation was compared using t-test and chi-square test, with the significance level of 0.05. Average number of drugs prescribed per prescription after the implementation was similar with that before the implementation (4.4 vs 4.6; p > 0.05). However, the proportion of generic drugs prescribed increased significantly after the formulary implementation (17.0% vs 52.7%; p < 0.05). Moreover, it was still significantly increased when the analysis was conducted only for antibacterial drugs (25.9% vs 72.0%; p < 0.05). Average drug cost per prescription was 34% lower after the intervention (p < 0.05), and the average cost for antibacterial drug was also decreased (26%). The use of antibacterial drugs was significantly decreased after the intervention (12.5% vs 6.9%; p < 0.05). The most often antibacterial drugs prescribed before the interventions were beta-lactams and macrolides; while quinolones were more increasingly used after the intervention. In conclusion, the implementation of evidence-based hospital drug formulary in a private hospital at Tanjung Enim, Sumatera Selatan significantly increase generic drug use and decreased antibacterial use and average drug cost per prescription.    Key words : drug formulary – prescribing pattern – generic drug – antibacterial – private hospital
Co-Authors Agustyas Tjiptaningrum Ahmad Fauzi Ahmad Fauzi Ahmad Sirajudin Alfi Yasmina Amira Zhafira Annisa Adietya Pratama Annisa Cahyani AYU WULANDARI Dian Isti Angraini Dian Isti Angraini Efrida Warganegara Elina Rahma Emantis Rosa Erna Kristin Febe Sintia Kristiani Fitria Saftarina Hasril Mulya Budiman Hendra Tarigan Sibero Hendra Tarigan Sibero Hendra Tarigan Subero Isti Angraini, Dian iwan Dwiprahasto Jarir At Thobari Karimah, Nisa Mayasari Diana Mayasari, Diana Muhamad Addin Syakir Muhammad Rafi Eka Putra Muhammad Syafei Hamzah Muhammad Yusran Nisa Karimah Novita Carolia Pairul, Piesta Prima Beta Piesta Prima Beta Pairul Putra, I Wayan Ardana Rahmatika, Achisna Rasmi Zakiah Oktarlina Rizki Hanriko Roro Rukmi Windi Perdani, Roro Rukmi Suharmanto Suharmanto Syahrul Hamidi Nasution Syazili Mustofa Tri Umiana Soleha Tri Umiana Soleha Umniya Umniya Yulisna Yulisna Yustisya Khoirunnisa Zetira, Zihan