<![CDATA[Background: Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in women of reproductive age. Acupuncture can improve menstrual cycle recovery and decrease body mass index (BMI) in women with PCOS. The effect of acupuncture can be enhanced by giving letrozol. Researchers are interested in knowing the comparison between letrozol therapy with letrozol + electroacupuncture on body weight, follicle count, and endometrial thickness in women with polycystic ovary syndrome. This study aims to determine the differences in weight loss, follicle number, and endometrial thickness in PCOS patients receiving letrozol treatment compared to letrozol + electroacupuncture.Subjects and Method: An observational analytic study using a case-control approach and fixed disease sampling technique was carried out at the Gynecology Polyclinic and Sekar Clinic at Dr Moewardi Hospital, Surakarta. Group 1 consisted of 15 infertile SOPK women who received letrozol and group 2 consisted of 15 infertile SOPK women who received electroacupuncture + letrozol. Body weight, follicle count, and endometrial thickness were measured in both groups. Data were analyzed univariate, bivariate and multivariate using the IBM-SPSS version 22 and STATA version 13 statistical applications.Results: There was a significant difference in the thickness of the endometrium (p= 0.008), the number of follicles on day 6 (p= 0.039), the number of follicles on day 8 (p= 0.033), the number of follicles on day 10 (p= 0.041), the number of follicles on day 12 (p= 0.041) ) with letrozol therapy with letrozol + electroacupuncture. There was no significant difference in body weight between groupsConclusion: There were significant differences between the letrozol group compared to the letrozol + electroacupuncture group in endometrial thickness and on the number of follicles on days 6, 8, 10, 12 in infertile PCOS women. However, there was no significant difference in body weight between groups.Keywords: number of follicles, endometrial thickness, PCOS, letrozol, electroacupunctureCorrespondence: Todung Antony Wesliaprilius. Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Sebelas Maret/ Dr. Moewardi hospital, Surakarta. Mobile: 08222181626 Email: todungtobing@gmail.com.Journal of Maternal and Child Health (2021), 06(02): 219-228https://doi.org/10.26911/thejmch.2021.06.02.09]]>
