<![CDATA[Background: Â Premature Rupture of Membrane (PROM) may cause maternal and neonatal morÂbiÂdity and mortality. This study aimed to inÂvesÂtiÂgaÂte the risk factors related to PROM in pregnant woÂmen below <35 years old.Subjects and Method: This cross-sectional stuÂdy was conducted in Kertha Usada General HosÂÂÂpital, North Bali, Indonesia. We collected 224 repoductive women using consecutive sampling. The dependent variable was premature rupture of membrane. The indeÂpenÂÂdent variables were graÂvidity status, gesÂtaÂtioÂnal age, body mass index (BMI), history of caeÂsaÂrean section, miscarriage, infection, and anemia. Data of infection was obtained from examination, such as neutroÂphil, lymphocyte, platelet, neutrophil-to-lymphoÂcyte ratio (NLR), and platelet-to-lymphocyte ratio (PLR). We also obtained Hb, MCV, and MCH as laboratory parameter of aneÂmia. The data were analyzed by a multiple logistic regressÂion.Results: Multigravida (or= 0.04; 95% CI= 0.01 to 0.27; p= 0.001) and MCH >34 pg (OR= 0.10; 95% CI= 0.01 to 0.86; p= 0.036) decreased the risk of premature of rupture membrane in women of reproductive age.Conclusion: Multigravida and MCH >34 pg decrease the risk of premature of rupture memÂbrane in women of reproductive age.Keywords: premature rupture membraneCorrespondence:Â Putri Chairani Eyanoer. Department Community and Preventive Medicine, Faculty of Medicine, UniÂÂversitas Sumatera Utara, Medan, Indonesia. Email: putrieyanoer@usu.ac.id. Mobile: +62-813 7023-2513Journal of Maternal and Child Health (2020), 5(4):Â 576-586https://doi.org/10.26911/thejmch.2020.05.04.04]]>
