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All Journal REKA KARSA Jurnal Online Mahasiswa (JOM) Bidang Keguruan dan Ilmu Pendidikan Jurnal Medika Hutama
Ayu Anggraini
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Biochemistry, Genetics & Molecular Biology Education Medicine & Pharmacology Nursing Public Health Veterinary

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MANFAAT ANTIOKSIDAN DAUN SALAM TERHADAP KADAR GLUKOSA DARAH DAN PENURUNAN APOPTOSIS NEURON DI HIPPOCAMPUS OTAK TIKUS YANG MENGALAMI DIABETES Ayu Anggraini
Jurnal Medika Hutama Vol. 2 No. 01 Oktober (2020): Jurnal Medika Hutama
Publisher : Yayasan Pendidikan Medika Indonesia

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Abstract

Encephalopathy diabetes is a complication of diabetes mellitus due to changes in morphology and abnormal physiological functions of the brain, due to chronic hyperglycemic conditions. Morphological changes that occur can include hippocampal brain atrophy, inflammation of nerves, changes in neurotransmitters, blood brain barrier injuries, energy metabolism disorders, and neuronal apoptosis. Increased apoptosis of these neurons occurs in the CA1 and CA3 layers of the pyramidal zone. Apoptosis of hippocampal neurons occurs through increased oxidative stress, deficits in mitochondrial function, impaired gene expression and inhibition of caspases. Antioxidants are compounds that can capture and reduce oxidative stress. Bay leaf is an antidiabetic plant that has high antioxidant properties, namely flavonoids and tannins. Flavonoids are antidiabetic compounds that reduce blood sugar levels which act as inhibitors of  glucosidase, maltase and  amylase enzymes. Flavonoids are also able to stimulate glucose uptake through GLUT-4 regulation. In addition to flavonoids, tannins are also antioxidants found in bay leaves and function as protectors of pancreatic beta cells from apoptosis due to oxidative stress. In addition, tannins can also increase levels of neurotropic factors and neuroastrocytes, injured brain, and modulate potential brain function so that can prevent neuronal apoptosis which is the main pathogenesis of diabetes.
Kajian Penerapan Material Ekspos pada Rumah Tinggal Ditinjau dari Segi Estetika Achsien Hidajat; Putri Hardiyanti; Ayu Anggraini; Dewi Yuliana
REKA KARSA Vol 1, No 2
Publisher : Institut Teknologi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26760/rekakarsa.v1i2.288

Abstract

Abstrak Rumah tinggal merupakan bangunan yang dijadikan tempat tinggal selama jangkawaktu tertentu, biasanya disesuaikan dengan suatu konsep tertentu agar mendapatkan kesan berbeda pada hasil yang ditampilkannya. salah satu konsep yang dapat diterapkan adalah konsep material ekspos. material ekspos merupakan desain pada bangunan yang dipandang sebagai bagian dari pekerjaan bangunan yang belum selesai atau tanpa proses finishing. kajian ini bertujuan untuk memahami penerapan konsep ekspos pada rumah tinggal agar memiliki nilai estetika yang baik. rumah tinggal setraduta k8/8 dipilih sebagai bahan studi kasus karena mengaplikasikan banyak variasi material pada konsep eksposnya. kajian material dibatasi pada material yang terdapat pada studi kasus saja karena material tersebut umum digunakan sebagai material ekspos. kajian estetika pun dibatasi dari segi warna dan tekstur saja karena merupakan pembeda antara bangunan ekspos dengan bangunan biasa. kajian ini diharapkan dapat menjadi bahan rujukan untuk mendesain bangunan rumah tinggal dengan konsep material ekspos agar memiliki nilai estetika yang baik. metoda penelitian yang digunakan adalah metoda analisis kualitatif yang terdiri dari proses pengamatan, pengumpulan data, penyaringan data, dan pengembangan teori tentang konsep material ekspos, jenis material ekspos, dan estetika. Kata Kunci: material ekspos, estetika tekstur dan warna, rumah tinggal. Abstract Residential building used as a residence for a certain period, usually tailored to a particular concept in order to get a different impression of the results of the display. One of the concepts that can be applied is the concept of material exposed. Exposed material is the design of the building is seen as part of an unfinished building work or without a finishing process. This study aims to understand the application of the concept of exposure in residences that have good aesthetic value. Setraduta residential k8 / 8 is selected as a case study for applying the many variations on the exposed material concept. The study material is limited to the material contained in the case studies just because the material is commonly used as a exposed material. Aesthetic study is limited in terms of color and texture only because it is the difference between building exposure to regular building. This study is expected to be a reference material for designing residential buildings with exposed material concepts that have good aesthetic value. The method used in this study is a qualitative analysis method which consists of a process of observation, data collection, data filtering, and material development of the theory of the concept of exposure, type of material exposure, and aesthetics. Keywords: exposed material, colors and textures aesthetic, residential building.
PENGEMBANGAN MEDIA PEMBELAJARAN BERBASIS KOMPUTER BERBANTUAN WORKSHEET UNTUK MATERI TURUNAN FUNGSI ALJABAR DI SMA/MA Ayu Anggraini; Armis Armis; Titi Solfitri
Jurnal Online Mahasiswa (JOM) Bidang Keguruan dan Ilmu Pendidikan Vol 5: Edisi 1 Januari-Juni 2018
Publisher : Jurnal Online Mahasiswa (JOM) Bidang Keguruan dan Ilmu Pendidikan

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Abstract : This research aims to develop computer-based learning media assisted by worksheet for derivative of algebra function. Development model using 4D model by Thiagarajan,et al there are (1) Define; (2) Design; (3) Develop; and (4) Disseminate. This research is limited to develop stage. On define stage, researcher make need analysis, on design stage make the paper based design, and on develop stage, media made by using Microsoft Office Power Point, then validated by four validators and revised based on validator's suggestion. Media was tested at two steps in class XI SMAN 8 Pekanbaru, there are small group test with six students and large group test with class XI MIA 10. Based on the results of data analysis obtained the result validation of media is 3,65 means very valid with the details are 3,56 for material aspect, 3,83 for learning aspect, 3,68 for program aspect, and 3,62 for display aspect, whereas for worksheet is 3,66 means very valid. Based on students questionnaire obtained the percentage of practicallity is 95,83% means very practice in small group test with the details 100% for material aspect, 97,2% for learning aspect, 91,67% for program aspect, and 91,67% language aspect. On the large group test obtained 94,25% means very practice with details are 92% for material aspect, 95,3% for learning aspect, 92% for program aspect, and 100% for language aspect. It can be concluded that computer-based learning media assisted by worksheet for derivative of algebra function are very valid and very practice for every aspects.Key Words: Computer-Based Learning, Research and Development, Derivative of Algebra Function.
PENATALAKSANAAN HOLISTIK PADA LANSIA USIA 68 TAHUN DENGAN TUBERKULOSIS PARU DENGAN PRINSIP PENDEKATAN KEDOKTERAN KELUARGA DI WILAYAH KERJA PUSKESMAS RAWAT INAP WAY KANDIS Ayu Anggraini
Jurnal Medika Hutama Vol. 5 No. 01 Oktober (2023): Jurnal Medika Hutama
Publisher : Yayasan Pendidikan Medika Indonesia

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Abstract

Background: Tuberculosis is a type of infectious disease which is still a health problem in developing countries, including Indonesia. WHO states that in 2019 tuberculosis cases are expected to reach 10 million cases with 44℅ cases in the Southeast Asia region. In Indonesia, in 2020 the number of tuberculosis cases found was 543,874 cases, this figure slightly decreased when compared to 2019 where there were 566,623 cases found. Meanwhile, the number of Tuberculosis cases in Lampung Province in 2020 reached 16,006 cases with a case discovery rate of 54.6%. Objective: Application of holistic management with family doctor service approach by identifying risk factors, clinical problems, management and prevention of disease in patients based on a problem-solving framework with patient-centered, community-oriented and family-oriented approach. Method: This study is a case report analysis. Primary data is taken from autoanamnesis and alloanamnesis, physical examination, and visits to the patient's home. Secondary data was taken from patient medical records. Results: Based on holistic diagnosis. The patient is diagnosed with pulmonary tuberculosis and has internal risk factors in the form of a lack of knowledge about tuberculosis transmission and behavior to prevent transmission. Visits were made 3 times. Evaluation results show clinical improvement, and changes in patient and family behavior. Conclusion: Holistic management with the principles of family medicine is effective in providing clinical improvement and changes in patient and family behavior.
Co-Authors Achsien Hidajat Armis Armis Dewi Yuliana Putri Hardiyanti Titi Solfitri