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All Journal Universa Medicina Journal La Medihealtico
Adnan, Endy
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Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Veterinary

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Body mass index as the most influential factor of high-sensitivity C-reactive protein in non-diabetic adults Mulyamin, Winda; Kurniawan, Liong Boy; Adnan, Endy; Widaningsih, Yuyun; Idris, Irfan; Santoso, Arif; Yustisia, Ika
Universa Medicina Vol. 40 No. 1 (2021)
Publisher : Faculty of Medicine, Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2021.v40.22-28

Abstract

BACKGROUNDHigh-sensitivity C-reactive protein (hsCRP) has been widely accepted as a predictor of future cardiovascular risk that reflects a microinflammatory state. Obesity linked to microinflammation increases the prevalence of metabolic disorders and cardiovascular diseases. This study aimed to determine the association between several obesity indices namely body mass index (BMI), waist circumference (WC), body fat percentage (fat), and visceral fat (VF) with hsCRP in non-diabetic adults. METHODSThis was a cross-sectional study performed on 80 non-diabetic adults with ages ranging from 20-40 years. The obesity indices BMI, WC, body fat percentage, and VF were measured. We then measured the hsCRP levels using an immunoturbidimetric method. Simple and multiple linear regression tests were used to analyze the association between obesity indices and hsCRP levels. RESULTSMean of log BMI, log WC, and log VF was 1.41 ± 0.08 kg/m2, 1.93 ± 0.06 cm, and 0.95 ± 0.27 units, respectively. Simple linear regression tests showed that log BMI (â=3.506; p<0.001), log WC (â=3.672; p<0.001), log VF (â=0.833; p<0.001), and log systolic blood pressure (â=3.739; p=0.024) had a significant positive correlation with log hsCRP levels. Further multiple linear regression test showed that log BMI (â=3.772; Beta=0.674; p<0.001) had the greater effect on log hsCRP levels compared to other indices. CONCLUSIONS    BMI had a greater influence on hsCRP levels compared to other obesity indices in non-diabetic adults. Body mass index can be used as a better index in predicting hsCRP levels compared to other indices.
The Role of Microbiota on the Incidence of Obesity Azzahra, Jihan; Bamahry, Aryanti R; Adnan, Endy
Journal La Medihealtico Vol. 5 No. 2 (2024): Journal La Medihealtico
Publisher : Newinera Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37899/journallamedihealtico.v5i2.1227

Abstract

Obesity is predicted to become a global public health problem, especially in developing countries. Obesity is characterized by a body mass index (BMI) of 30 or more, which is calculated by dividing a person's weight by the square of their height (in kilograms per square meter). The incidence of obesity by age increased from 4.6% in 1980 to 14.0% in 2019. According to the World Health Organization (WHO), around 2 billion adults are classified as overweight, while another 650 million people are categorized as obese. Based on a national survey, the obesity rate in Indonesia is 23.1%, while in South Sulawesi province it is 31.6% (Riskesdas, 2018). This can alter the gut microbiota structurally and functionally, and the gut microbiota can also modulate nutritional status. A certain abundance and diversity of bacteria may facilitate energy storage and metabolic pathways that lead to obesity. Dietary interventions with probiotics, prebiotics, or synbiotics may be effective in counteracting the disturbances observed in the gut microbiota during obesity or unbalanced diets, as they may be able to reduce and maintain body weight. Intestinal anaerobic bacteria, including Firmicute and bacteroids, can hydrolyze carbohydrates that cannot be digested by the intestine, obtaining short chain fatty acids (SCFA) including acetate, propionate and butyrate, which have an impact on human health. Therefore, anaerobic bacteria can inhibit obesity.
Effectiveness of Chronic Disease Management Program in Lowering Blood Pressure in Hypertensive Patients: Literature Review Akbar, Muhammad Alief; Wahid, Syarifuddin; Lestari, Indah; Adnan, Endy; Indarwati, Rezky Putri
Journal La Medihealtico Vol. 5 No. 4 (2024): Journal La Medihealtico
Publisher : Newinera Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37899/journallamedihealtico.v5i4.1606

Abstract

Chronic illnesses are a global health issue that kills people. Hypertension is a blood vessel disorder that compromises the body's tissues' oxygen and nutrient supply. In 2025, 1.5 billion people will have hypertension, and 9.4 million will die from it. This research review evaluates the Chronic Disease Management Program's blood pressure-lowering effects in hypertensive patients. A PRISMA Flow Diagram-based literature review. Downloading scientific papers from PubMed, Portal Garuda, and Google Scholar follows SINTA IV and V criteria. This article searches for Prolanis, blood pressure, and hypertension. Search results yielded 103 articles. Using inclusion criteria, 11 research publications were chosen for review. The study found that the chronic disease management program, which included medical consultations, Prolanis participant education, SMS gateway reminders, home visits, club activities (exercise), and health status monitoring, effectively lowered blood pressure in hypertension patients.
Co-Authors Akbar, Muhammad Alief Arif Santoso Azzahra, Jihan Bamahry, Aryanti R Indah Lestari, Indah Indarwati, Rezky Putri IRFAN IDRIS Liong Boy Kurniawan, Liong Boy Mulyamin, Winda Syarifuddin Wahid Widaningsih, Yuyun Yustisia, Ika