Safitri, Lina Eta
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Nicotine Chewing Gum and Its Correlation with Smoking Cessation: A Meta-Analysis Hartono, Roni; Safitri, Lina Eta
Journal of Epidemiology and Public Health Vol 6, No 2 (2021)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

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Abstract

Background: Smoking is a human behavior that has a very bad impact on health. Mortality and morbidity due to smoking cannot be under­estimated. Non-communicable diseases become high morbidity among smokers, such as diabetes, reduced fertility, coronary heart disease, and countless health complications. This study aims to analyze the effect of the use of nicotine gum on the success of smoking cessation based on a number of previous similar studies.  Subjects and Method: This is a systematic review and meta-analysis conducted by follow­ing the PRISMA flow diagram. The process of searching for articles through a journal data­base which includes: Google Scholar by select­ing articles published in 2010-2020. With key­words, among others: “Nicotine Replacement Therapy” OR Gum Nicotine-” AND “Smoking cessation. The inclusion criteria were full paper articles with experimental study design, articles in English, bivariate analysis with Odds Ratio. Eligible articles were analyzed using the Revman 5.3 app.Results: A total of five articles were reviewed in this study using a randomized controlled trial design. A meta-analysis of five randomized controlled trials showed that 0.81 times the use of nicotine gum did not help smokers quit smoking compared with placebo (OR 0.81; 95% CI 0.48 to 2.12; p = 0.400).Conclusion: Nicotine gum does not help smokers to quit smoking.Keywords: Gum Nicotine, smoking cessation, SmokeCorrespondence: Roni Hartono. Faculty of Psychology, Univer­sitas Teknologi Sumbawa, Jl. Raya Olat Maras, Batu Alang, Moyo Hulu, 84371, Sumbawa Besar. Email: roni.hartono@uts.ac.idJournal of Epidemiology and Public Health (2021), 06(02): 170-176https://doi.org/10.26911/jepublichealth.2021.06.02.04
Meta-Analysis the Effect of Nicotine Replacement Therapy on the Successful Smoking Cessation Safitri, Lina Eta; Kristiyanto, Agus; Murti, Bhisma
Journal of Epidemiology and Public Health Vol 6, No 1 (2021)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

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Background: About 23% of the world's population smokes, which includes 32% of men with the highest prevalence coming from Indonesia and 7% are women. East Asia and Southeast Asia have the highest smoking prevalence in the world at around 45%, while in Indonesia, the problem of smoking is a serious threat due to the increasing preva­lence of smoking at 18 years of age from 7.2% to 9.1%. This study aims to analyze the magnitude of the effect of using NRT on the success of smoking cessation based on a number of previous similar studies.Subjects and Method: This research is a systematic review and meta-analysis carried out by following the PRISMA flow diagram. The process of searching for articles through a journal database which includes: Google Scholar, PubMed, and Science Direct by selecting articles published in 2011-2020. Keywords used include: "nicotine replace­ment therapy" AND "smoker" OR "smoking" AND "smoking cessation". The inclusion criteria were a full paper article with an observational study design, English and Indonesian, and analyzed using multivariate analysis with adjusted odds ratio. Articles that meet the requirements were analyzed using the Revman 5.3 application.Results: Nine articles were reviewed in this study with a cohort study design. A meta-analysis of nine cohort studies showed that use of nicotine replacement therapy was 1.42 fold increased smoking cessation success compared to placebo (aOR 1.42; 95% CI 1.14 to 1.76; p <0.002).Conclusion: Nicotine replacement therapy improves smoking cessation success.Keywords: nicotine replacement therapy, smoking cessationCorrespondence: Lina Eta Safitri. Masters Program in Public Health, Universitas Sebelas Maret, Jl. Ir. Sutami 36A, Surakarta 57126, Central Java. Email: Linaetasafitri_96@student.uns.ac.idJournal of Epidemiology and Public Health (2021), 06(01): 21-32https://doi.org/10.26911/jepublichealth.2021.06.01.03