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All Journal HAYATI Journal of Biosciences BERKALA FISIKA Jurnal Matematika & Sains Omega: Jurnal Fisika dan Pendidikan Fisika Journal of Multidisciplinary Academic
Agus Kartono
IPB University
Agriculture, Biological Sciences & Forestry Earth & Planetary Sciences Education Engineering Mathematics Physics Social Sciences

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Study of Pseudostate Expansion in a Simplified Model of Elastic Electron Scattering from Helium Agus Kartono; Toto Winata
Jurnal Matematika & Sains Vol 10, No 2 (2005)
Publisher : Institut Teknologi Bandung

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Abstract

In this paper, we present a simplified model of electron-helium scattering in which all terms involving nonzero orbital angular momentum are neglected. Elastic scattering cross sections are calculated for this model by using the close-coupling expansion with a non-orthogonal Laguerre-L2 basis function. It is found that the results are in good agreement with experiments and with the other theoretical results.
L2 Discretization of the Coulomb Three-body Problem in A Non-orthogonal Laguerre-function Basis Agus Kartono
Jurnal Matematika & Sains Vol 11, No 2 (2006)
Publisher : Institut Teknologi Bandung

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Abstract

In this paper a general analysis of the three-body Coulomb potential polynomials was presented. The three-body Coulomb wave functions expansion in a non-orthogonal Laguerre-type base function is shown to give two modified Pollaczek polynomials. The frozen-core model is used to examine the three-body Coulomb Hamiltonian. The resulting three-term recurrence relation is a special case of the Pollaczek polynomials which is a set of orthogonal polynomials having a nonempty continuous spectrum in addition to an infinite discrete spectrum. The completeness of the three-body Coulomb wave functions is further studied for different Laguerre basis size.
The Application of Non-orthogonal Laguerre L2 Basis to the Calculation of the Differential and Integrated Cross Sections for the Electron Impact Elastic and Excitation of the 21S, 21P, 23S, 23P States of Helium at Intermediate Energy Agus Kartono; Toto Winata
Jurnal Matematika & Sains Vol 12, No 1 (2007)
Publisher : Institut Teknologi Bandung

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Abstract

The non-orthogonal Laguerre L2 basis has been applied in the intermediate energy region (30, 40 and 50 eV) for the electron impact elastic and excitation of 21S, 21P, 23S and 23P states of helium. Differential and integrated cross sections are calculated and compared with recent experiments. The results for each case are discussed and compared with other calculation. It is found that the results agree quite well with experiments and with the other results.
Nonuniqueness Solution Forms of Close-Coupling Equations for e-He Scattering Agus Kartono; Toto Winata
Jurnal Matematika & Sains Vol 8, No 3 (2003)
Publisher : Institut Teknologi Bandung

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Abstract

The close-coupling method relies on the reformulation of the Schrödinger equation into an infinite set of coupledchannel equations by expanding over the complete set of target states. The target states approach will be used is a restricted basis for helium states in which one of the electrons is in a fixed orbital (1s) while the second electron is described by a set of independent L2 functions, thus permitting it to span the discrete and continuum excitations. This type of approximate description of the target should be good for scattering problems in which the dominant reaction mechanism is by one-particle (electron) excitations. We will also show why the standard close-coupling expansion gives rise to nonunique solutions.
Simulating the Aerodynamics Profiles of NACA 4312 Airfoil in Various Incoming Airspeed and Gurney Flap Angle Sumaryada, Tony; Jaya, Achmad Muharam; Kartono, Agus
Omega: Jurnal Fisika dan Pendidikan Fisika Vol 4 No 1 (2018)
Publisher : Program Studi Pendidikan Fisika UHAMKA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31758/OmegaJPhysPhysEduc.v4i1.1

Abstract

Simulations of the aerodynamics performance of NACA 4312 airfoil at various gurney flap angles and incoming airspeed (wind velocities) have been conducted. The gurney flaps size was set at 5.0% length of the chord line. Two airfoil models with gurney flap at 45° and 90° were simulated and compared with the results of plain airfoil (without gurney flap) model with the incoming airspeed of 10.0 m/s, 70.0 m/s and 200.0 m/s. The results have shown that increasing the value of gurney flap angle to 45° and 90° will increase the lifting force of the airfoil and decrease the drag force.
Studi Awal Pemodelan Perlakuan Virotherapy Yang Menggunakan Virus Campak Pada Tumor Paru-Paru Tikus Kartono, Agus; Sunjono, Sunjono; Arif, Ardian
BERKALA FISIKA Vol 13, No 2 (2010): Berkala Fisika, Edisi Khusus
Publisher : BERKALA FISIKA

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Abstract

The interaction model dynamics between tumor and viruses based on the interaction phenomenon between the three populations, namely: population of uninfected tumor cells, tumor cell population infected with the virus and the virus population. This study aimed to see the interaction between non-infected tumor cells, tumor cells infected with viruses and viruses, so it can be modeled using virotherapy treatment of measles virus in mouse lung tumors. Model parameters obtained from experimental data. Numerical Solution of the models suggest that the dose of the virus play an important role in determining the outcome of tumor therapy. Tumor growth can be slowed by using this virotherapy, but the tumor can not be killed as a whole. Keywords: model dynamics, virotherapy, measles virus, mouse lung tumors
Studi Awal Pemodelan Perlakuan Virotherapy yang Menggunakan Virus Campak pada Tumor Paru-paru Tikus Kartono, Agus; Sunjono, Sunjono; Arif, Ardian
BERKALA FISIKA Vol 13, No 4 (2010): Berkala Fisika
Publisher : BERKALA FISIKA

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Abstract

The interaction model dynamics between tumor and viruses based on the interaction phenomenon between the three populations, namely: population of uninfected tumor cells, tumor cell population infected with the virus and the virus population. This study aimed to see the interaction between non-infected tumor cells, tumor cells infected with viruses and viruses, so it can be modeled using virotherapy treatment of measles virus in mouse lung tumors. Model parameters obtained from experimental data. Numerical Solution of the models suggest that the dose of the virus play an important role in determining the outcome of tumor therapy. Tumor growth can be slowed by using this virotherapy, but the tumor can not be killed as a whole. Keywords: model dynamics, virotherapy, measles virus, mouse lung tumors t; mu � ni�o� P� :IN'> viscosity, indeks of refraction, transparent liquid 
Solusi Numerik Model Dinamik Perlakuan Immunotherapy pada Infeksi HIV-1 Kartono, Agus; Rosidah, Rosidah; Arif, Ardian
BERKALA FISIKA Vol 13, No 1 (2010): Berkala Fisika
Publisher : BERKALA FISIKA

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Abstract

There are several types of treatment options that can slow the progression of HIV that can be offered if the number of CD4 + cells has been known for certain, one treatment is by immunotherapy with interleukin-2 (IL-2). This type of treatment is to increase the immune system that can help the body fight against the infection itself. Efforts to raise an immune response would be appropriate to reduce the amount of virus. This brings new hope for treatment of HIV infection and the type of treatment is being researched. Interleukin-2 (IL-2) is most of the cytokines which are proteins made by the body. T-helper cells, a type of white blood cells, produce IL-2 when they were stimulated by infection. In this study, a model of HIV disease progression than individuals not treated can be expressed in a mathematical model, and also expressed immunotherapy model to see the dynamics of viral populations and the population of CD4 + T cells from HIV disease based on ordinary differential equation (ODE). This study aims to calculate the numerical solution immunotherapy mathematical model in HIV infection and a mathematical model to predict the outcome of immunotherapy treatment strategies in HIV infection. Keywords: HIV, CD4 + T cells, immunotherapy, mathematical modeling
In-Silico Design of Novel Glucagon-Like Peptide 1 Mutants as Candidate for New Peptide Agonist Drugs Tony Sumaryada; Ajeng Widya Roslia; Alfi Afifah; Setyanto Tri Wahyudi; Agus Kartono
HAYATI Journal of Biosciences Vol. 28 No. 1 (2021): January 2021
Publisher : Bogor Agricultural University, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.4308/hjb.28.1.92

Abstract

The binding of glucagon-like peptide 1 (GLP-1) incretin hormone and its receptor GLP-1R plays an important role in the human body. The GLP-1 acts as the insulin secretion stimulator through a GLP-1R agonist activation to avoid the type 2 diabetes mellitus problem. A recent development in computational sciences has enabled us to design a new GLP-1 mutant which has a better binding stability to GLP-1R. In this paper, we have conducted an in-depth analysis of protein-protein docking of GLP-1 and GLP-1R receptor to determine the responsible factors affecting the binding stability. The protein-protein binding stability was analyzed by performing the point mutations on the GLP-1 structure and running the molecular dynamics simulation of the docked structures. Five mutants, Lys20Arg, Lys20His, Lys20Ser, Lys20Gly, and Lys20Ala, has been created computationally and docked with GLP-1R and tested via a molecular dynamics simulation and the free energy perturbation calculation to search for the best-binding mutant. Our results have shown that the Lys20His mutant design has the best potential to be developed as a new peptide agonist drug based on its binding affinity and structural integrity as compared to other mutants and the peptide agonist drugs available in the market exenatide, and liraglutide.
Numerical FEM Models of Bio-heat Transfer for Magnetic Fluid Hyperthermia Treatments Febri Dwi Irawati; Agus Kartono
Journal of Multidisciplinary Academic Vol 5, No 1 (2021): Science, Engineering and Social Science Series
Publisher : Penerbit Kemala Indonesia

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Abstract

Numerical solutions using the Finite Element Method (FEM) of one-dimensional bio-heat transfer of healthy and cancerous tissue together with the Magnetic Fluid Hyperthermia treatment have been worked out successfully. Each layer shows the characteristics of tissue. Each layer represents an independent biological tissue characterized by temperature-dependent physiological parameters and linear temperature-dependent metabolic heat generation. Magnetic fluid hyperthermia (MFH) is used as an external heat source to heat the cancerous area. In a transient state MFH treatments can heat up cancerous tissue without damaging healthy tissue as indicated by an increase in the temperature of the cancer tissue according to the standard temperature of the MFH treatments.
Co-Authors Ajeng Widya Roslia Alfi Afifah Ardian Arif Febri Dwi Irawati Jaya, Achmad Muharam Rosidah Rosidah Setyanto Tri Wahyudi Sumaryada, Tony Sunjono Sunjono Toto Winata