The impact of hospitalization on children who are hospitalized can cause an anxiety reaction forparents. Some parental anxiety responses can be minimized by providing a complete orientationto parents regarding the process of hospitalization and treatment of children. This study aims todetermine the relationship between orientation and the level of anxiety of parents facinghospitalization in school-age children. This research method uses a descriptive correlation designwith a cross sectional approach. The sampling method used is probability sampling withpurposive sampling technique. The number of samples in this study were 37 respondents. Thedata collection tool used is a questionnaire. The data analysis technique used the Spearman Rank(rho) statistical test. The results of data analysis showed the value of r = 0.512 and p-value = 0.001which means that there is a significant relationship between orientation and the level of anxietyof parents facing hospitalization in school-age children. Giving room orientation to new patientscan be said to be good and the level of anxiety experienced by parents is a mild level of anxiety. Inconnection with the results of this study, the role of nurses is needed in providing a completeorientation to parents whose children are hospitalized so as to reduce the level of parentalanxiety.