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All Journal Jurnal Pengolahan Hasil Perikanan Indonesia Media Farmasi : Jurnal Ilmu Farmasi (Journal Of Pharmaceutical Science) Marinade Creative Research Journal JFIOnline JURNAL ILMU KEFARMASIAN INDONESIA Jurnal Jamu Indonesia Pharmaceutical Sciences and Research (PSR)
Effionora Anwar
Universitas Indonesia
Agriculture, Biological Sciences & Forestry Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Decision Sciences, Operations Research & Management Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Other

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The Content of Vitamin C and E on Seaweed Porridge Eucheuma cottonii and Turbinaria conoides Yanuarti, Rini; Nurjanah, Nurjanah; Anwar, Effionora; Pratama, Ginanjar
Marinade Vol 1 No 01 (2018): Marinade
Publisher : Fisheries Product Technology Department, Faculty of Marine Science and Fisheries, Universitas Maritim Raja Ali Haji

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.3345/marinade.v1i01.785

Abstract

Seaweed was a source of vitamin C and E. They were an antioxidant contained in seaweed. The objective of this study was to determine of vitamins (C and E) in the seaweed porridge of E. cottonii and T. conoides were thought to have potential as raw material for making sunscreen cream. The methods were included total microbial analysis, vitamin C and E analysis on seaweed porridge. The results of a total microbial assay on E. cottonii was 8,7x103 colony/g while on T. conoides was 3,5x104 colony/g. They were the safe category of microbial test. The content of vitamin C on E. cottonii and T. conoides (1: 1) on seaweed porridge was 0,07 mg/100 gram, while vitamin E content obtained is 10 mg/100 gram.
Pengembangan Teknologi Tepat Guna (TTG) Rumput Laut tropika sebagai bahan baku kosmetik Hidayat, Taufik; Nurjanah, Nurjanah; Anwar, Effionora; Nurilmala, Mala
Creative Research Journal Vol 3, No 01 (2017)
Publisher : Badan Penelitian dan Pengembangan Daerah (BP2D) Provinsi Jawa Barat

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (501.64 KB)

Abstract

Rumput laut saat ini menjadi komoditas prima yang menjadi nilai ekonomis penting bagi bangsa Indonesia. Nawa Cita Presiden Jokowi yang mengutamakan pentingnya daya saing produk menjadikan rumput laut menjadi komoditas utama untuk dijadikan produk yang mempunyai nilai saing dan dapat dikembangkan oleh pelaku usaha industry menengah ke bawah atau yang sering disebut UMKM. Salah satunya produk kosmetik. peneltian ini bertujuan menentukan desain prototype teknologi tepat guna dan formulasi produk kosmetik (tabir surya).  metode yang digunakan yaitu dengan pengujian standar alat, dan formulasi produk dengan metode trial dan eror. hasil penelitian ini menunjukkan bahwa  rumput laut yang cocok digunakan dalam pembuatan krim tabir surya adalah rumput laut merah dan coklat.Hasil aktivitas antioksidan pada rumput laut merah yaitu  120 ppm dan rumput laut coklat 150 ppm. untuk aktivitas antioksidan  bubur rumput laut merah dan coklat masing-masing yaitu 120 ppm dan 125 ppm. krim tabir surya yang dihasilkan bebas dari mikroba sesuai dengan standar SNI. 
The Content of Vitamin C and E on Seaweed Porridge Eucheuma cottonii and Turbinaria conoides Yanuarti, Rini; Nurjanah, Nurjanah; Anwar, Effionora; Pratama, Ginanjar
Marinade Vol 1 No 01 (2018): Marinade
Publisher : Fisheries Product Technology Department, Faculty of Marine Science and Fisheries, Universitas Maritim Raja Ali Haji

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Seaweed was a source of vitamin C and E. They were an antioxidant contained in seaweed. The objective of this study was to determine of vitamins (C and E) in the seaweed porridge of E. cottonii and T. conoides were thought to have potential as raw material for making sunscreen cream. The methods were included total microbial analysis, vitamin C and E analysis on seaweed porridge. The results of a total microbial assay on E. cottonii was 8,7x103 colony/g while on T. conoides was 3,5x104 colony/g. They were the safe category of microbial test. The content of vitamin C on E. cottonii and T. conoides (1: 1) on seaweed porridge was 0,07 mg/100 gram, while vitamin E content obtained is 10 mg/100 gram.
FORMULASI GEL MENGGUNAKAN SERBUK DAGING IKAN HARUAN (Channa striatus) SEBAGAI PENYEMBUH LUKA Rahmawanty, Dina; Anwar, Effionora; Bahtiar, Anton
Media Farmasi: Jurnal Ilmu Farmasi Vol 11, No 1: Maret 2014
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (4147.172 KB) | DOI: 10.12928/mf.v11i1.1395

Abstract

Daging  ikan  haruan  (Channa  striatus)  dipercaya  dapat  digunakan  untuk menyembuhkan  luka  karena  mengandung  protein,  asam  amino  esensial,  lemak dan  asam  lemak  yang  berperan  dalam  proses  penyembuhan  luka.  Tujuan  dari penelitian  ini  ialah  membuat  gel  yang mengandung  serbuk  daging  ikan  haruan sebagai penyembuh luka. Pada penelitian ini digunakan serbuk daging ikan haruan (Channa striatus) sebagai zat aktif sebanyak 1 gram pada formula 1 dan 2 gram pada  formula  2.  Serbuk  daging  ikan  haruan  dibuat  suspensi  dengan  ukuran partikel nanometer dengan metode gelasi ionik menggunakan kitosan dan natrium tripolifosfat,  kemudian  dibuat  menjadi  bentuk  sedian  gel  dengan  menggunakan gelling agentHPMC. Suspensi yang dihasilkan dilakukan karakterisasi fisika dan kimia. Hasil karakterisasi suspensi formula 1 dan formula 2 adalah sebagai berikut :  ukuran  partikel  berturut-turut  491,8  -  665,5  nm,  481,8  – 828,1  nm;  indeks polidispersitas 0,512, 0,456; nilai potensial zeta (+)29,15mV, (+)29,35mV; kedua formula  mempunyai  partikel  berbentuk  sferis.  Sediaan  gel  yang  dihasilkan dievaluasi  aktivitas  penyembuhan  luka  secara  in  vivo.  Dari  hasil  uji  in  vivo sediaan gel serbuk daging ikan haruan dapat digunakan sebagai penyembuh luka. Kata  Kunci:  gel,  gelasi  ionik,  haruan  (Channa  striatus),  kitosan,  natrium tripolifosfat, luka.
Koproses Karagenan-Pragelatinasi Pati Singkong Propionat sebagai Eksipien Sediaan Tablet Mengapung Junaedi, .; Iskandarsyah, .; Anwar, Effionora
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol 6, No 4 (2013)
Publisher : Indonesian Research Gateway

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (311.675 KB)

Abstract

The aim of this study was to prepare floating tablet dosage forms using coprocessed of kappa and iota carrageenan and pregelatinized cassava starch propionate (PPSP) as excipients. In this study, tablets were made by wet granulation method and using famotidine as a model drug. Several formulations of floating tablets were prepared using varying composition of the excipients coprossed carragenan with a certain ratio. The swelling and bupyancy of the floating tablets were evaluated. Furthermore, the drug release from the floating tablets were studied and analyzed using several models of kinetic equations. The result showed that formula A with excipients coprocessed carragenan (1:1) as much as 60% with 10% HPMC produce the best formula with floating lag time 11.42±1.53 minutes and total floating time for 22 hours. The formula also revealed a profile of controlled drug release and approached to Higuchi kinetics model and the non Fickian diffusion mechanism.Keywords : carragenan, PCSP, coprocess exipients, floating tablets.
Formulasi Nanopartikel Verapamil Hidroklorida dari Kitosan dan Natrium Tripolifosfat dengan Metode Gelasi Ionik Iswandana, Raditya; Anwar, Effionora; Jufri, Mahdi
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol 6, No 4 (2013)
Publisher : Indonesian Research Gateway

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (807.205 KB)

Abstract

Nanopraticles can be prepared by several methods and the ionic gelation method is the easiest one. Verapamil hydrochloride is a drug which used as antiarrhythmic, antiangina, and antihypertension therapy. Nevertheless, bioavailability of orally administered verapamil is very low, only about 10 to 23%. Therefore, verapamil hydrochloride was prepared as nanoparticles dosage form to increase its  bioavailability. The purpose of the present study was to optimize ionic gelation method of chitosan and sodium tripolyphosphate to obtain the best nanoparticles formulation. Nanoparticles were obtained from four different methods (formula A, B, C and D). Particle size distribution, zeta potential, entrapment efficiency, morphology, and fourier transform infra red spectrum of each nanoparticles formula were characterized. The chosen formula was formula D which has 62.8 nm of size, 59.15% of entrapment efficiency, ±25.46 mV of zeta potential, spherical shape, and the ionic interaction was confirmed by FT-IR spectrum. The result showed that chitosan-tripolyphosphate succesfully produce the verapamil hydrochloride nanoparticles by ionic gelation method.Keywords: chitosan, ionic gelation, nanoparticles, sodium tripolyphosphate, verapamil hydrochloride
Formulasi Nanopartikel Verapamil Hidroklorida dari Kitosan dan Natrium Tripolifosfat dengan Metode Gelasi Ionik Iswandana, Raditya; Anwar, Effionora; Jufri, Mahdi
Jurnal Farmasi Indonesia Vol 6, No 4 (2013)
Publisher : Jurnal Farmasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (807.205 KB) | DOI: 10.35617/jfi.v6i4.142

Abstract

Nanopraticles can be prepared by several methods and the ionic gelation method is the easiest one. Verapamil hydrochloride is a drug which used as antiarrhythmic, antiangina, and antihypertension therapy. Nevertheless, bioavailability of orally administered verapamil is very low, only about 10 to 23%. Therefore, verapamil hydrochloride was prepared as nanoparticles dosage form to increase its  bioavailability. The purpose of the present study was to optimize ionic gelation method of chitosan and sodium tripolyphosphate to obtain the best nanoparticles formulation. Nanoparticles were obtained from four different methods (formula A, B, C and D). Particle size distribution, zeta potential, entrapment efficiency, morphology, and fourier transform infra red spectrum of each nanoparticles formula were characterized. The chosen formula was formula D which has 62.8 nm of size, 59.15% of entrapment efficiency, ±25.46 mV of zeta potential, spherical shape, and the ionic interaction was confirmed by FT-IR spectrum. The result showed that chitosan-tripolyphosphate succesfully produce the verapamil hydrochloride nanoparticles by ionic gelation method.Keywords: chitosan, ionic gelation, nanoparticles, sodium tripolyphosphate, verapamil hydrochloride
Koproses Karagenan-Pragelatinasi Pati Singkong Propionat sebagai Eksipien Sediaan Tablet Mengapung Junaedi, .; Iskandarsyah, .; Anwar, Effionora
Jurnal Farmasi Indonesia Vol 6, No 4 (2013)
Publisher : Jurnal Farmasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (311.675 KB) | DOI: 10.35617/jfi.v6i4.140

Abstract

The aim of this study was to prepare floating tablet dosage forms using coprocessed of kappa and iota carrageenan and pregelatinized cassava starch propionate (PPSP) as excipients. In this study, tablets were made by wet granulation method and using famotidine as a model drug. Several formulations of floating tablets were prepared using varying composition of the excipients coprossed carragenan with a certain ratio. The swelling and bupyancy of the floating tablets were evaluated. Furthermore, the drug release from the floating tablets were studied and analyzed using several models of kinetic equations. The result showed that formula A with excipients coprocessed carragenan (1:1) as much as 60% with 10% HPMC produce the best formula with floating lag time 11.42±1.53 minutes and total floating time for 22 hours. The formula also revealed a profile of controlled drug release and approached to Higuchi kinetics model and the non Fickian diffusion mechanism.Keywords : carragenan, PCSP, coprocess exipients, floating tablets.
Nilai sun protection factor anggur laut segar dengan metode dan jenis pelarut ekstraksi yang berbeda: SPF Value of Fresh Sea Grape Extract from Different Solvent and Method of Extraction Ayun Erwina Arifianti; Rizky Clarinta Putri; Salsabiela Haz Ekaputri; Wanda Nisrina Aqilah; Effionora Anwar
Jurnal Pengolahan Hasil Perikanan Indonesia Vol 23 No 1 (2020): Jurnal Pengolahan Hasil Perikanan Indonesia 23(1)
Publisher : Department of Aquatic Product Technology IPB University in collaboration with Masyarakat Pengolahan Hasil Perikanan Indonesia (MPHPI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (180.416 KB) | DOI: 10.17844/jphpi.v23i1.30692

Abstract

Kanker kulit melanoma merupakan satu dari sembilan belas kanker yang sering terjadi di seluruh dunia. Kebutuhan akan adanya alternatif zat aktif tabir surya menjadi sangat penting terutama dari bahan alam laut yaitu anggur laut (Caulerpa sp.). Penelitian ini bertujuan untuk menentukan nilai SPF ekstrak cair anggur laut segar dengan metode ekstraksi yang berbeda. Metode ekstraksi dilakukan dengan dua cara yaitu maserasi dan microwave-assisted extraction (MAE) masing-masing dengan tiga jenis pelarut (etanol, air, dan etanol-air 1:1). Ekstrak cair yang dihasilkan diukur pH dan ditentukan nilai SPF secara invitro menggunakan spektrofotometer UV-Vis. Ekstrak cair anggur laut segar dengan nilai SPF in vitro tertinggi kemudian dianalisis aktivitas antioksidannya menggunakan metode DPPH. Ekstrak cair yang dihasilkan berbau amis, dan berwarna hijau dengan intensitas warna yang berbeda. Interaksi antara perlakuan metode ekstraksi dan jenis pelarut menunjukkan perbedaan signifikan terhadap nilai pH ekstrak cair anggur laut segar. Nilai SPF dari ekstrak maserasi etanol, air, dan etanol-air berturut-turut 0,583; 3,099; 2,911 sedangkan ekstrakMAE 3,807; 5,555; 4,979. Metode MAE menunjukkan nilai SPF in vitro yang lebih tinggi secara signifikan daripada maserasi tanpa melihat perbedaan pelarut.Hasil persentase penghambatan DPPH dari ekstrak MAE dengan pelarut etanol, air, dan etanol-air pada konsentrasi 106 mg/mL berturut-turut 33,85%; 22,99%; 17,44%. Aktivitas antioksidan ekstrak etanol dengan metode ekstraksi MAE lebih tinggi daripada ekstrak dengan pelarut lainnya namun tidak lebih tinggi dibandingkan dengan asam askorbat sebagai pembanding.
Pemanfaatan Kitosan Tersambung Silang dengan Tripolifosfat sebagai Eksipien Gel Ikan Haruan (Channa Striatus) DINA RAHMAWANTY; EFFIONORA ANWAR; ANTON BAHTIAR
JURNAL ILMU KEFARMASIAN INDONESIA Vol 13 No 1 (2015): JIFI
Publisher : Fakultas Farmasi Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (482.179 KB)

Abstract

Meat of snakehead fish (Channa striatus) has been reported can be used for wound healing because contains proteins, essential amino acids, lipid and fatty acids that inuenced wound healing process. The present study was performed in order to formulate gels contain meat powders of snakehead fish for wound healing. The formulas were used 1 g (formula 1) and 2 g (formula 2) meat powder of snakehead fish as an active ingredient. Meat powder of snakehead fish have been made nanosuspension use ionic gelation method with chitosan and sodium tripolyphosphate and formulated to gel form using HPMC as gelling agent. Suspenses have been physicochemical charactheried. The results showed that suspenses (formula 1 and formula 2) have particle sie in range of 41.665.5 nm and 41.2.1 nm respectively polidispersity inde of 0.512 and 0.456 respectively eta potential ()2.15 m and ()2.35 m respectively both of formulas have spherical particles.
Co-Authors . Chaidir . Harianto . Iskandarsyah, . Abdul Munim ABDUL MUN’IM Animar J Aswin Anisa Amalia Antokalina SV Antokalina SV, Antokalina Anton Bahtiar ANTON BAHTIAR Anton Bahtiar Arry Yanuar Ayun Erwina Arifianti Bahtiar, Anton Berna Elya Cahyaningsih, Umi Chaidir Chaidir Chaidir Chaidir DEVI RATNASARI DINA RAHMAWANTY Engkom Komariah Erny Sagita Erny Sagita Erny Sagita, Erny FADLINA CHANY Fadlina Chany Saputri FAUZIAH MAPPAMASING Firda Wery Ginanjar Pratama Harianto Harianto Henry . Joshita D Joshita Djajadisastra Joshita Djajadisastra Joshita Djajadisastra, Joshita Junaedi Junaedi Junaedi, . Junaedi, . KS, Yunita L B S.Kardono Liza Ariantina Mahdi Jufri Mahdi Jufri Mahdi Jufri Mala Nurilmala Nurjanah - - Nursanti Nursanti Nursanti Nursanti Putri Margaining Utami Putri Margaining Utami, Putri Margaining Raditya Iswandana Rahmawanty, Dina Rangga Pradana Rangga Pradana Rangga Pradana, Rangga Rizky Clarinta Putri Rosmala Dewi Rosmala Dewi Sabrina Dahlizar Salsabiela Haz Ekaputri Silvia Surini Silvia Surini Silvia Surini SITI MARDIYANTI Siti Sa’diah Taufik Hidayat Wanda Nisrina Aqilah Yanuarti, Rini Yoga Yuniadi Yunita K S Yunita K S Yunita K S