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All Journal Hemera Zoa Jurnal Ilmiah Mahasiswa Veteriner Jurnal Ilmiah Ilmu-Ilmu Peternakan
T Armansyah TR
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Veterinary

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PCS-3 Toxicity Sub-cronic Ethanolic Extract of Malaka (Phyllanthus emblica) Leaves on Kidney Function of Mice (Mus musculus) be Reviewed from Blood Creatinin Level N Asmilia; D Aliza; T Armansyah TR; Rusli Rusli; N Tridayanti
Hemera Zoa Proceedings of the 20th FAVA & the 15th KIVNAS PDHI 2018
Publisher : Hemera Zoa

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (418.526 KB)

Abstract

Herbal medicine is still the mainstay of about 75-80% of the whole population, and the major part of traditional therapy involves the use of plant extract and their active constituents in the indigenous. The plant genus Phyllantus is widely distributed in most of tropical and subtropical countries like China, India, Southeast Asia and Indonesia [1,2]. Phyllantus spesies have long been used in folk medicine to tread a broad spectrum of disorders. Phyllantus emblica or Indian gooseberry (Figure 1), belonging to family Euphorbeaceae has been reported to have antioxidant, anti-inflammatory, anticancer, adaptogenic, anti-diabetic, antimicrobial and immunomodulatory potential [3]. The aim of the study was to investigate the effect of ethanolic extract of malaka leaves (Phyllanthus emblica) on renal function by analyzing creatinine level in mice blood (Mus musculus).
DAYA HAMBAT EKSTRAK ETANOL DAUN SIRSAK (Annona muricata L.) TERHADAP PERTUMBUHAN JAMUR Aspergillus sp. Hotnida Shofiah Hasibuan; Erina Erina; T Armansyah TR
JURNAL ILMIAH MAHASISWA VETERINER Vol 5, No 2 (2021): FEBRUARI-APRIL
Publisher : JURNAL ILMIAH MAHASISWA VETERINER

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/jim vet..v5i2.16525

Abstract

ABSTRAK       Aspergillus sp. merupakan kapang yang menginfeksi hewan dan manusia dapat menyebabkan penyakit aspergillosis. Penelitian ini bertujuan untuk melihat daya hambat ekstrak etanol daun sirsak (Annona muricata L.) terhadap pertumbuhan jamur Aspergillus sp. dengan metode difusi lempeng agar (Kirby Bauer). Ekstrak etanol daun sirsak (Annona muricata L.) dibuat dalam konsentrasi 10%; 20%; 30%; 40%; dan 50% dengan kontrol positif nistatin dan kontrol negatif akuades. Aktivitas ekstrak etanol daun sirsak (Annona muricata L.) terhadap pertumbuhan jamur Aspergillus sp. dengan konsentrasi 10%; 20%; 30%; 40% dan 50% sebesar 0 mm. Kontrol positif nistatin memiliki rata-rata zona hambat 16 mm, kontrol negatif aquades 0 mm. Tidak adanya zona hambat yang terbentuk pada kertas cakram ekstrak etanol daun sirsak (Annona muricata L.) dengan konsentrasi 10%; 20%; 30%; 40%; dan 50%. Oleh sebab itu dapat disimpulkan bahwa ekstrak etanol daun sirsak  tidak dapat menghambat pertumbuhan jamur Aspergillus sp.Kata kunci: Aspergillus sp., daun sirsak  (Annona muricata L.), daya hambat ABSTRACT                    Aspergillus sp. is a fungus that infects animals and humans and can cause aspergillosis. This study aims to determine the inhibition power of the ethanol extract of soursop (Annona muricata L.) leaves on the growth of the fungus Aspergillus sp. with the agar plate diffusion method (Kirby Bauer). The ethanol extract of soursop (Annona muricata L.) leaves was prepared in concentration 10%; 20%; 30%; 40%; and 50% with nystatin positive control and aquadest negative control. The activity of ethanol extract of soursop (Annona muricata L.) leaves on the growth of Aspergillus sp. with a concentration of 10%; 20%; 30%; 40% and 50% of 0 mm. Nystatin positive control had an average inhibition zone of 16 mm, negative control 0 mm aquadest. The absence of an inhibition zone formed on the disc paper of the ethanol extract of soursop (Annona muricata L.) leaves with a concentration of 10%; 20%; 30%; 40%; and 50%. Therefore, it can be concluded that the ethanol extract of soursop leaves cannot inhibit the growth of Aspergillus sp. Keywords: Aspergillus sp., leaves of soursop (Annona muricata L.), inhibition
GAMBARAN HISTOPATOLOGIS LIMPA JANTAN IKAN MUJAIR (Oreochromis mossambicus) YANG TERPAPAR MERKURI KLORIDA (HgCl2) Muzdalifah Mariska; Nazaruddin Nazaruddin; T Armansyah TR
JURNAL ILMIAH MAHASISWA VETERINER Vol 4, No 1 (2019): NOVEMBER-JANUARI
Publisher : JURNAL ILMIAH MAHASISWA VETERINER

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/jim vet..v4i1.4842

Abstract

ABSTRAK Penelitian ini bertujuan mengetahui efek paparan merkuri klorida (HgCl2) terhadap gambaran histopatologis limpa ikan mujair. Penelitian ini merupakan penelitian eksperimental dengan rancangan acak lengkap (RAL) faktorial yang menggunakan 36 ekor ikan mujair yang dikelompokkan ke dalam 4 kelompok perlakuan, yaitu kelompok kontrol (P0) kelompok yang tidak diberikan paparan merkuri dan kelompok perlakuan P1, P2, dan P3 yang diberikan paparan merkuri dengan konsentrasi masing-masing 0,25; 0,50; dan 0,75 ppm per 100 liter air, masing-masing kelompok terdiri atas 9 ekor ikan. Pengambilan sampel dilakukan pada hari ke-10, 20, dan 30 untuk dibuat preparat histopatologis. Data yang diperoleh dianalisis secara statistik dan deskriptif. Hasil penelitian menunjukkan bahwa gambaran histopatologis limpa mengalami perubahan berupa meningkatnya jumlah melanomakrofag centres (MMC), nekrosis, vakuolisasi, edema, dan pada hari ke-30 setelah pemaparan ditemukan proliferasi jaringan ikat. Jumlah MMC pada hari ke-10 masing-masing kelompok perlakuan 15,00±5,57; 85,67±14,98; 110,67±16,68; 160,33±16,77, pada hari ke-20 masing-masing kelompok perlakuan 22,00±7; 116,67±14,47; 114±6,24; 134,33±16,50; dan pada hari ke-30 masing-masing kelompok perlakuan 20,00±4,36; 121,33±15,04; 133,33±14,47; 142,00±34,22. Hasil analisis statistik menunjukkan bahwa konsentrasi HgCl2 berpengaruh nyata (P0,05) terhadap jumlah MMC limpa ikan mujair, namun lama paparan dan interaksi tidak menunjukkan pengaruh yang nyata (P0,05). Disimpulkan bahwa paparan HgCl2 pada ikan mujair menyebabkan perubahan gambaran histopatologis limpa yang ditandai dengan meningkatnya jumlah MMC, nekrosis, vakuolisasi, edema, dan proliferasi jaringan ikat.ABSTRACT This study aimed to determine the effect of mercury chloride (HgCl2) exposure on histopathologic of spleen tilapia fish. This research was an experimental study using Completely Randomized Design factorial pattern used 36 tilapia fish grouped into 4 treatment groups, control (P0) was without exposed by mercury and treatment group P1, P2, and P3 exposed by mercury with a concentration of 0.25; 0.50; and 0.75 ppm per 100 liters of water, each group contained 9 fish. Sampling was conducted on 10, 20, and 30 days then proceed to histopathology preparations. The data obtained were analyzed statistically and descriptively. The results showed that histopathologic of spleen reveated the increasing number of melanomakrofag centres (MMC), necrosis, vacuolation,  oedema, and proliferation of connective tissue on the 30th day. The number of MMC on day 10 of each treatment group was 15,00±5.57; 85.67±14.98; 110.67±16.6;, 160.33±16.77; on day 20 of each treatment group was 22,00±7; 116.67±14.47; 114±6.24; 134.33±16.50; and on day 30 of each treatment group was 20,00±4.36; 121.33±15.04; 133.33±14.47; 142,00±34.22. The result of analysis of variance (anava) factorial with 95% confidence level showed that HgCl2 concentration significantly (P0.05) to MMC in spleen of mujair fish, but long exposure and interaction did not show significant effect (P0.05). In conclusion, HgCl2 exposure in tilapia fish causes spleen damage characterized by the increase number of MMC, necrosis, vacuolation, oedema, and proliferation of connective tissue.
PENGARUH PENAMBAHAN PERASAN AIR JERUK PURUT (Citrus hystrix) PADA PROSES PEMBUATAN TELUR ASIN TERHADAP JUMLAH TOTAL BAKTERI Riski Ayu Maulida; Azhari Azhari; Rastina Rastina; Siti Rani Ayuti; Fakhrurrazi Fakhrurrazi; M Daud AK; T Armansyah TR
JURNAL ILMIAH MAHASISWA VETERINER Vol 6, No 3 (2022): MEI-JULI
Publisher : JURNAL ILMIAH MAHASISWA VETERINER

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/jim vet..v6i3.18942

Abstract

ABSTRAK          Telur itik merupakan salah satu produk hasil pengawetan telur dengan cara pengasinan. Penelitian ini bertujuan mengetahui pengaruh penambahan air perasan jeruk purut (Citrus hystrix) pada proses pembuatan telur asin terhadap jumlah total cemaran bakteri. Metode penelitian yang digunakan adalah metode rancangan acak lengkap (RAL) yang terdiri atas 4 perlakuan dan 3 kali ulangan. Perlakuan yang diberikan adalah penambahan larutan perasan jeruk purut dengan konsentrasi 0%, 10%, 20% dan 30% ke dalam media adonan pengasinan telur itik. Pengamatan jumlah total bakteri dilakukan setelah proses pengasinan telur dilakukan yaitu setelah 14 hari masa penyimpanan telur. Pengamatan jumlah total bakteri dilakukan dengan  metode Total Plate Count (TPC) menggunakan media Plate count agar (PCA).  Data jumlah bakteri yang diperoleh di analisis secara statistik menggunakan Analysis Of Variance (ANOVA). Hasil penelitian menunjukkan bahwa penambahan larutan perasan jeruk purut dengan konsentrasi 0%, 10%, 20% dan 30% ke dalam adonan pengasin telur selama proses pembuatan telur asin dapat menurunkan jumlah total bakteri secara signifikan. Hasil uji lanjut menggunakan uji Duncan diketahui bahwa penambahan larutan perasan jeruk purut dengan konsentrasi 30% secara nyata dapat menurunkan jumlah total bakteri pada telur asin yang dihasilkan dibandingkan dengan konsentrasi 0%, 10%, 20%. Sedangkan pembahan larutan perasan jeruk purut dengan konsentrasi 10% sampai dengan 20% tidak dapat menurunkan jumlah total bakteri pada telur asin yang dihasilkan. Berdasarkan penelitian ini dapat disimpulkan bahwa penambahan larutan perasan jeruk purut dengan konsentrasi 30% ke dalam adonan pengasin telur dapat menurunkan jumlah total bakteri pada telur asin yang dihasilkan. ABSTRACT            Duck egg is a product of egg preservation by salting.This study aims to determine the effect of adding citrus hystrix to the process of making salted eggs to the total amount of bacterial contamination. The research method used is a complete randomized design method (RAL) consisting of 4 treatments and 3 replays. The treatment given is the addition of a solution of orange juice purut with a concentration of 0%, 10%, 20% and 30% into the medium of duck egg marinating dough. Observation of the total number of microbes is done after the process of salting eggs is done after 14 days of egg acidification. Observation of the total number of microbes is done by the Method of Total Plate Count (TPC) using media Plate count agar (PCA) Data on the number of microbes obtained in statistical Analysis Of Variance (ANOVA). The results showed that the addition of a solution of orange juice purut with concentrations of 0%, 10%, 20% and 30% into the egg marinating dough during the process of making salted eggs can significantly decrease the total number of microbes. The results of further tests using Duncan's test found that the addition of a solution of orange juice purut with a concentration of 30% can significantly decrease the total number of microbes in the salted eggs produced compared to the concentration of 0%, 10%, 20%. While the deity of orange juice solution purut with a concentration of 10% to 20% can not decrease the total number of microbes in salted eggs produced. Based on this research, it can be concluded that the addition of a solution of orange juice purut with a concentration of 30% into the egg marinating dough can decrease the total number of microbes in the resulting salted eggs.
Aktivitas Hepatoprotektif Ekstrak Etanol Daun Kucing-kucingan Acalypha indica L.) pada Tikus Putih (Rattus Novergicus) yang Diinduksi Parasetamol T Armansyah TR; Amalia Sutriana; Dwinna Aliza; Henni Vanda; erdiansyah rahmi
Jurnal Ilmiah Ilmu-Ilmu Peternakan Vol. 13 No. 6 (2010): Mei 2010
Publisher : Fakultas Peternakan Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (56.896 KB) | DOI: 10.22437/jiiip.v0i0.120

Abstract

The  research  has  been  conducted  to  determine  hepatoprotective  effect  of  ethanolic  extract  of Acalypha  indica  L.  leaves  on  rats  (Rattus  novergicus)  induced  with  paracetamol.  The  study  was performed  following  a  completely  randomized  design, using  45 male  rats  (Rattus  novergicus)  divided into  5  groups.  Rats  in  group  1  (K1)  were  given  CMC  1  %  for  7  days  and  followed  by  aquadest administration 8 hours post given CMC on day 7. Group 2 was given CMC 1 % for 7 days and treated with paracetamol at dose 2,5 g/kg BW 8 hours post given CMC on day 7. Groups 3 (K3), 4 (K4), and 5 (K5) were pretreated with ethanolic extract of Acalypha indica L.  leaves at the dose of 50, 100, and 200 mg/kg BW for 7 days respectively, followed by paracetamol administration at the dose of 2.5 g/kg BW in the  next  8  hours  on  day  7. Paracetamol  hepatotoxicity  and  extracts  activity were measured  based  on SGPT and SGOT activity level on day 0, 8 hours after  last administration of  extract on day 7, and 24 hours post paracetamol administration. Data were analyzed using one way ANOVA. The result showed that  the  administration  of  ethanolic  extract  of Acalypha  indica  leaves  at  the  dose  of  50,  100,  and  200 mg/kg BW was  significantly  reduced SGPT  and SGOT  level  (P<0,05)  in  rats  that were  induced with paracetamol. Based on the results of SGPT and SGOT serum activity, it can be concluded that ethanolic extract of Acalypha indica L. potential as hepatoprotective agent.
Co-Authors Abd. Rasyid Syamsuri Amalia Sutriana Azhari Azhari D Aliza Dwinna Aliza Erdiansyah Rahmi Erdiansyah Rahmi Erina Erina Fakhrurrazi Fakhrurrazi Henni Vanda Hotnida Shofiah Hasibuan M Daud AK Muzdalifah Mariska N Asmilia N Tridayanti Nazaruddin Nazaruddin Rastina Rastina Riski Ayu Maulida Siti Rani Ayuti