Edwin Armawan
Departemen Obstetri dan Ginekologi Fakultas Kedokteran Universitas Padjadjaran/Rumah Sakit Dr. Hasan Sadikin Bandung

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PERBANDINGAN KERAPATAN KOLAGEN LIGAMENTUM SAKROUTERINA PADA PASIEN DENGAN DAN TANPA PROLAPS UTERI Silitonga, Intan Renata; Sukarsa, M. Rizkar A.; Pohan, Lasma R.; Armawan, Edwin; Handono, Budi
Majalah Kedokteran Bandung Vol 47, No 4 (2015)
Publisher : Faculty of Medicine, Universitas Padjadjaran

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Abstract

Kerapatan kolagen merupakan satu faktor penting dalam kejadian prolaps uteri. Beberapa penelitian menunjukkan pasien prolaps uteri mempunyai kerapatan kolagen ligamentum sakrouterina yang rendah. Penelitian ini bertujuan mengukur perbedaan kerapatan kolagen ligamentum sakrouterina pada pasien dengan dan tanpa prolaps uteri. Penelitian ini adalah penelitian analitik komparatif dengan case control study terhadap 16 pasien prolaps uteri dan 16 pasien tanpa prolaps uteri di Rumah Sakit Dr. Hasan Sadikin Bandung dan RS jejaring. Bahan penelitian diambil dari ligamentum sakrouterina saat operasi histerektomi lalu dibuat sediaan dengan pewarnaan hematoksilin-eosin dan Masson?s trichrome. Uji kemaknaan menggunakan uji Mann-Whitney. Hasil penelitian didapatkan hubungan bermakna antara kerapatan kolagen dan kejadian prolaps uteri, yaitu kerapatan kolagen pada pasien prolaps uteri lebih rendah (15,3%) dibanding dengan tanpa prolaps uteri (48,75%). Cut-off point kerapatan kolagen ligamentum sakrouterina untuk prediksi prolaps uteri adalah ? 30%; sensitivitas 93,8%; spesifisitas 87,5%; dan akurasi 90,6%. Simpulan penelitian ini adalah bahwa kerapatan kolagen ligamentum sakrouterina pada pasien prolaps uteri lebih rendah dibanding dengan pasien tanpa prolaps uteri. Cut-off point kerapatan kolagen ligamentum sakrouterina yang dapat memprediksi prolaps uteri adalah ? 30%. [MKB. 2015;47(4):212?7]Kata kunci: Kerapatan kolagen, ligamentum sakrouterina, prolaps uteriThe Comparison of Uterosacral Ligament Collagen Density in Patients with and without Uterine ProlapseAbstractCollagen density is one important factor in uterine prolapse. Several studies has shown that uterine prolapse patients have lower uterosacral ligament collagen density. The purpose of this study was to reveal the uterosacral ligament collagen density differences in patients with and without uterine prolapse. This case control study was an analitic comparative research of 16 uterine prolapse patients and 16 patients without uterine prolapse who underwent hysterectomy in Dr. Hasan Sadikin General Hospital Bandung and its networking hospitals during November?December 2008. Uterosacral ligament was sampled and then stained using HE and Masson?s trichrome staining. The significance of the result was analyzed using Mann-Whitney. The study found a significant correlation between collagen density and uterine prolapse, with the collagen density of uterine prolapse patients was lower (15.3%) than patients without uterine prolapse (48.75%). The uterosacral ligament collagen density cut-off point in predicting women having uterine prolapse was ?30%; with 93.8% sensitivity, 87.5% specificity, and 90.6% accuracy. The conclusion of this study is that uterosacral ligament collagen density in patients with uterine prolapse is lower (15.3%) than patients without uterine prolapse (48.75%). The uterosacral ligament collagen density cut-off point in predicting a women having uterine prolapse is ?30%. [MKB. 2015;47(4):212?7] DOI: 10.15395/mkb.v47n4.624
Total Serum Level of Calcium and Ion Calcium is Lower in Hypotonic Uterine Inertia Wattimury, Josef; Permadi, Wiryawan; Armawan, Edwin
Indonesian Journal of Obstetrics and Gynecology Volume. 1, No. 3, July 2013
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (90.642 KB) | DOI: 10.32771/inajog.v1i3.354

Abstract

Objectives: To know the correlation between total and ion serum calcium level with the uterine contractility of laboring patient. Methods: This is a cross-sectional analytic correlative study measuring the strength of correlation of total and ion calcium serum level between groups with hypotonic uterine inertia - and normal labor. Each group consists of 20 subjects who met inclusion criteria and presented to Dr. Hasan Sadikin Hospital in August - September 2012. Statistical analysis was performed by using Eta (η) coefficient. Results: Mean total calcium serum level on hypotonic uterine inertia is 6.66 mg/dl, while mean of total calcium serum level on normal labor is 8.56 mg/dl, with Eta (η) correlation coefficient 0.721. Mean ion calcium serum level on hypotonic uterine inertia is 4.14 mg/dl, while mean of total calcium serum level on normal labor is 4.92 mg/dl, with Eta (η) correlation coefficient 0.802. Conclusion: Total serum level of calcium and ion calcium in hypotonic uterine inertia is lower than the level of which in normal labor. There is a strong correlation between total and ion serum calcium level with uterine contractility, the Eta (η) correlation coefficient are 0.721 and 0.802 respectively. [Indones J Obstet Gynecol 2013; 1-3: 145-8] Keywords: hypotonic uterine inertia, ion serum calcium level, normal labor, total serum calcium level
FAKTOR RISIKO PENDERITA PROLAPSUS ORGAN PANGGUL TERHADAP HIATUS GENITALIS, PANJANG TOTAL VAGINA, DAN PERINEAL BODY Purwara, Benny Hasan; Armawan, Edwin; Sasotya, R. M. Sonny; Achmad, Eppy Darmadi
Majalah Kedokteran Bandung Vol 46, No 1 (2014)
Publisher : Faculty of Medicine, Universitas Padjadjaran

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Abstract

Prolapsus organ panggul (POP) merupakan kondisi yang umum pada perempuan usia lanjut. Keluhannya bersifat prolapsus organ panggul (POP) merupakan kondisi umum bersifat progresif pada perempuan usia lanjut. Saat ini belum ada laporan mengenai hubungan antara komponen faktor risiko dan anatomi. Penelitian ini untuk mengetahui faktor risiko klinis POP serta pengaruhnya pada komponen anatomi penentu tahapan klinis kelainan tersebut. Penelitian dilakukan di Departemen Obstetri dan Ginekologi Fakultas Kedokteran Unpad/Rumah Sakit Dr. Hasan Sadikin Bandung periode Desember 2009?Mei 2010. Limapuluh dua pasien POP dibagi menjadi dua kelompok yaitu 30 subjek POP tingkat III dan 22 POP tingkat I-II. POP berasosiasi signifikan dengan usia, paritas, menopause, serta TSH. Usia ?50 tahun (OR=0,08; 95% IK=0,018-0,333 versus <50 tahun), paritas ?3 (OR=5,56; 95% IK=0,02-0,55 versus paritas <3), dan status menopause (OR=5,14; 95% IK=1,18-22,49 versus tidak menopause). Korelasi positif signifikan panjang hiatus genitalis (HG) dengan usia (r=0,656) dan paritas (r=0,539). Ukuran perineal body (PB) korelasi negatif signifikan dengan usia (r= -0,298) dan paritas (r=-0,335). Kelompok menopause menunjukkan peningkatan panjang HG dan penurunan ukuran PB yang signifikan. Panjang PB meningkat signifikan pada kelompok yang menerima TSH. Hubungan yang signifikan antara panjang total vagina (PTV) dan faktor-faktor risiko hanya menemukan pemendekan PTV signifikan pada usia >50 tahun. Simpulan, usia, paritas, dan menopause merupakan faktor risiko kemungkinan POP serta mempunyai korelasi dengan panjang GH dan PB dan progresivitas POP. [MKB. 2014;46(1):57?60]Kata kunci: Hiatus genitalis, panjang total vagina, perineal body, prolapsus organ panggulRisk Factors for Patients with Pelvic Organ Prolapse on Hiatus Genitalis, Total Vaginal Length, and Perineal BodyPelvic organ prolapse (POP) is a common and progressive condition in elderly women. Currently, there are no report regarding the relationship between risk factor and anatomical components. This research was to identify risk factors and its influence on the POP clinical anatomy component determining clinical stages of this disorder. The study was conducted at the Department of Obstetrics and Gynaecology, Faculty of Medicine Universitas Padjadjaran/Dr. Hasan Sadikin General Hospital Bandung during the period of December 2009?May 2010. Fifty-two POP patients were participated, 30 subjects were in grade III and 22 subjects were in grade I?II. Found a significant association between age, parity, menopause, and hormone replacement therapy (HRT) and the incidence POP. Age >50 years (OR=0.08, 95% CI=0.018 to 0.333 versus <50 years), parity >3 (OR=5.56, 95% C1=0.02 to 0.55 versus parity <3), and menopausal status (OR=5.14, 95% CI=1.18 to 22.59 versus not menopausal). Long hiatus genetalis (HG) had a significant positive correlation to age (r=0.656), while HG had a significant positive correlation to parity (r=0.539). Size of the perineal body (PB) showed a significant negative correlation with age (r=-0.298) and parity (r=-0.335). Menopausal group showed significant increase in HG length and decrease in size of the PB compared to the premenopausal group. The PB length increased significantly in those receiving HRT (p=0.018). Significant relationship between total length of the vagina (PTV) and the risk factors was only found in the form of significant shortening of PTV at aged >50 years. In conclusion, age, parity, and menopause are risk factors for POP probability and has a correlation with HG length, PB and progression of POP. [MKB. 2014;46(1):57?60]Key words: Genital hiatus, pelvic organ prolapse, perinael body, total vaginal length DOI: 10.15395/mkb.v46n1.229
Visual Inspection Test with Acetic Acid for Cervical Cancer Screening: Willingness and Acceptability among Reproductive Age and Married Women Hassan, Rozaliamisah Binti; Armawan, Edwin; Arya, Insi Farisa Desy
Althea Medical Journal Vol 5, No 2 (2018)
Publisher : Althea Medical Journal

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Abstract

Background: Cervical cancer is a preventable disease, thus early screening test should be performed for early cervical cancer prevention. Previous studies showed that among all of the screening techniques, visual inspection with acetic acid is an alternative, simple safe cervical cancer prevention technique. This study aimed to identify the willingness and acceptability of visual inspection with acetic acid among reproductive age and married women as cervical cancer prevention.Methods: A descriptive cross-sectional study was conducted among 100 reproductive age and married women in Jatinangor subdistrict West Java in 2014. A validated questionnaire was used to obtain information about the respondents’s characteristics, risk factors of cervical cancer, willingness and acceptability of Visual Inspection using Acetic Acid Test (VIA). The collected data were presented using tables.Results: Out of 100 respondents, 93% ever heard of cervical cancer, however 79% were aware of cervical cancer. As high as 96% were aware of the importance of cervical cancer screening, however 36% were aware of cervical cancer screening, and 19% were aware of VIA test. While 83% never had previous education on cervical cancer, 91% reported willingness to take part on cervical cancer education and 83% willingness of cervical cancer screening. Noted 17% were non-acceptance of VIA test for future cervical cancer screening due to their busy life and afraid of the outcome result.Conclusions: The majority of reproductive age and married women  are willing and accept VIA test for cervical cancer screening.