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Enikarmila Asni
Faculty of Medicine Universitas Riau
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Medicine & Pharmacology

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HISTOPATOLOGI AORTA TORASIKA Rattus novergicus STRAIN WISTAR JANTAN SETELAH 8 MINGGU PEMBERIAN DIET ATEROGENIK Welinsa, Fatya; Asni, Enikarmila; Malik, Zulkifli
Jurnal Online Mahasiswa (JOM) Bidang Kedokteran Vol 2, No 1 (2015): Wisuda Februari 2015
Publisher : Jurnal Online Mahasiswa (JOM) Bidang Kedokteran

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ABSTRACTAtherosclerosis could be induced in animal model (Rattus novergicus) by feeding atherogenic diet consist of standart feed, cholesterol 2 % from yolk, 5 % goat fat, 0,2% cholic acid and induction with vitamin D3. The goal of this research was to analyze histopathological of thoracic aorta on male Rattus novergicus strain wistar after fed atherogenic diet for 8 weeks. This research was an experimental laboratory research with post test only with control design. Twelve male rats were segregated into two groups (n=6) labelled as control fed standart and atherogenic fed group. After 8 weeks thoracic aorta was taken and histological slides were made and colored with hematoxylin eosin and then measured with atherosclerosis score. The result showed that in atherogenic group there are macrophage, foam cell, and intracellular lipid accumulation with 100% percentage, extracellular lipid accumulation 33,33% (for a little extracellular lipid) and 66,67 (a lot of extracellular lipid) while control group there are macrophage, foam cell, and intracellular lipid accumulation with 33,33% percentage. The statistical test result show there is significant difference between control group and atherogenic group (p=0,003). As conclusion, there is significant difference between control group and atherogenic group.Keywords : Atherosclerosis, atherogenic diet, thoracic aorta
GAMBARAN KRISTAL HEMOGLOBIN PADA BERCAK DARAH YANG TERPAPAR PADA BEBERAPA ZAT PEMBERSIH LANTAI DOMESTIK NON KARBOL Sari, Yessi Gusvita; Asni, Enikarmila; Indrayana, Mohammad Tegar
Jurnal Online Mahasiswa (JOM) Bidang Kedokteran Vol 2, No 2 (2015): Wisuda Oktober 2015
Publisher : Jurnal Online Mahasiswa (JOM) Bidang Kedokteran

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ABSTRACTBloodstain is an evidence that often found in criminal case. Bloodstain which is found on a crime scene often already contaminated, there might be an effort to clean up the bloodstain on the floor by using floor cleaner agents. The exposure of cleaning agents potentially damaging membrane cell and denature protein inside the blood, so at the time when forensic examination of bloodstain has been done it is possible to generate different interpretations. This research is a descriptive research with experimental laboratory design to find out the description of haemoglobin crystal on bloodstain exposed by some non carbolic domestic floor cleaner agent using Teichmann test and Takayama test. This research shows that haemoglobin crystal can be found on eighty slide of bloodstain which has been flowed and swabbed by non carbolic domestic floor cleaner agents. The conclusion of this research is no effect of the exposure by non carbolic domestic floor cleaner agent against haemoglobin crystal description on the Teichmann and Takayama test.Keywords : bloodstain, non carbolic domestic floor cleaner agent, Teichmann test, Takayama test
Gambaran Kristal Hemoglobin pada Bercak Darah yang Terpapar Beberapa Sabun Krim Menggunakan Tes Teichmann dan Takayama Pangaribuan, Welly N; Asni, Enikarmila; Indrayana, Mohammad Tegar
Jurnal Online Mahasiswa (JOM) Bidang Kedokteran Vol 2, No 2 (2015): Wisuda Oktober 2015
Publisher : Jurnal Online Mahasiswa (JOM) Bidang Kedokteran

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ABSTRACTThe biologic sample like bloodstains are precious physical evidence thatcan be found at any crime scene. Bloodstains that be found can indicate struggleor murderer case and identification of bloodstains found at criminal scene cangive information about actual criminal acts. The criminals often try to remove orcamouflage bloodstains by using cleaning agents like cream detergent that makesbloodstains contamined with detergent surfactant and may be affect the chemicalbloodstains identification using Teichmann and Takayama test. The purposes ofthis experiment are to know the description of hemoglobin crystal at contaminedbloodstain with some cream detergents using Teichmann and Takayama test. Thisexperiment is the experimental description. This experiment has done inBiochemical Laboratory Medical Faculty of Riau University. There’re 38 slidesthat made in this experiment with twice experiment (duplo). The bloodstain slideswere washed using cream detergent A, B, C, D, E, and F once until three times.The result of this experiment was positive in all bloodstain slide that washed bycream detergent when it tested with Teichmann and Takayama test.Keywords: bloodstain, hemoglobin crystal, cream detergent, Teichmann andTakayama.
KRISTAL HEMOGLOBIN PADA BERCAK DARAH YANG TERPAPAR BEBERAPA DETERJEN CAIR MELALUI TES TEICHMANN DAN TES TAKAYAMA Pratiwi, Nurfi; Asni, Enikarmila; Indrayana, Mohammad Tegar
Jurnal Online Mahasiswa (JOM) Bidang Kedokteran Vol 2, No 2 (2015): Wisuda Oktober 2015
Publisher : Jurnal Online Mahasiswa (JOM) Bidang Kedokteran

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ABSTRACTBloodstain were could be found on a lot of form of violence. Bloodstain atthe crime scene often cleaned by the offender to cover the crime. One of thecleaning agents that might be used by the offender is liquid detergent. Thebloodstain that has been contaminated by liquid detergent could give a differentrepresentation on the forensic bloodstain examination. This study was conductedto determine the formation of hemoglobin crystal on contaminated bloodstain bysome liquid detergents using Teichmann and Takayama test. Each driedbloodstains over the slides were flowed by liquid detergent solutions, thenexamined if the hemoglobin cystal were formed or not. In this study, there were atotal of 28 slides were studied and obtained positive results in all slides (100%)through Teichmann or Takayama test. The results of this study showed thathemoglobin crystals can still be found in the bloodstain that had beencontaminated by liquid detergent through Teichmann and Takayama test.Therefore, the conclusion of this study is liquid detergents that used can not affectthe formation of hemoglobin crystal using Teichmann and Takayama tests..Kata kunci: bloodstain, hemoglobin crystal, liquid detergent, Teichmann,Takayama
KRISTAL HEMOGLOBIN PADA BERCAK DARAH YANG TERPAPAR BEBERAPA DETERJEN BUBUK KHUSUS MESIN CUCI MENGGUNAKAN TES TEICHMANN DAN TES TAKAYAMA Vitriani, Viras; Asni, Enikarmila; Indrayana, Mohammad Tegar
Jurnal Online Mahasiswa (JOM) Bidang Kedokteran Vol 2, No 2 (2015): Wisuda Oktober 2015
Publisher : Jurnal Online Mahasiswa (JOM) Bidang Kedokteran

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ABSTRACTBloodstains are evidence which might be found in the scene of crime cases. However, the bloodstains are not always found intact as a result of criminal’s attempt to destroy the evidence by using cleaning agent for example detergent. The bloodstains which have been contaminated by detergent might give a different forensic examination result. This study has an aim to determine the formation of hemoglobin crystal on contaminated bloodstain using Teichmann test and Takayama test. In this study, there were five powder detergent solutions flowed onto bloodstained slides for each tests. The result shows that all 11 slides (100%) still have positive result which means the hemoglobin crystal still can be found in the contaminated bloodstain using Teichmann test and Takayama test. The conclusion of this study is the detergent powder for washing machine that used might not affect the formation of hemoglobin crystal using Teichmann test and Takayama test..Kata kunci: Bloodstain, detergent powder, hemoglobin crystals, Teichmann test, Takayama test.
HUBUNGAN LAMA PEMBERIAN DIET ATEROGENIK TERHADAP KADAR KOLESTEROL TOTAL Rattus novergicus JANTAN STRAIN WISTAR Pratiwi, Fanny; Asni, Enikarmila; ", Fridayenti; ", Ismawati
Jurnal Online Mahasiswa (JOM) Bidang Kedokteran Vol 2, No 2 (2015): Wisuda Oktober 2015
Publisher : Jurnal Online Mahasiswa (JOM) Bidang Kedokteran

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ABSTRACTCardiovascular disease is the number one cause of death globally in the world. One of the cardiovascular risk factor is hypercholesterolemic, signed by high total cholesterol levels in the blood. The purpose of this research is to know the correlation of given atherogenic diet duration toward total cholesterol level in male Wistar rat. This research is an experimental research with the post test-only control group design approach using 2-3 months old male rats (Rattus novergicus) with 160-240 g average weight range. The rats were divided into 4 groups such as control group given with standard diet, the 5 weeks atherogenic diet group, the 8 weeks atherogenic group, and the 12 weeks atherogenic group, each group consists of 6 rats. The atherogenic diet (2% cholesterol of egg yolk, 5% goat’s fat, and 0,2% cholic acid) is given amount to 20 g/each/day. Then cholesterol total serum was measured with CHOD-PAP method in the fifth week ,the eighth week and the twelfth week. The result of this research shows a significant difference (p=0,000). As for the post hoc test (p=0,000), there is a statistically significant difference within the experimental groups. In the Spearman test (0,967), there is a significant positive correlation between the given duration of the atherogenic diet toward the total cholesterol level. In this research we can conclude that the longer duration of the atherogenic diet is, the higher the cholesterol total in male Wistar rats (Rattus novergicus) will be.Keywords : Atherogenic diet, total cholesterol, rats (Rattus novergicus)
Kristal Hemoglobin pada Bercak Darah yang Terpapar dengan Beberapa Sabun Mandi Antiseptik Padat Menggunakan Tes Teichmann dan Tes Takayama Umara, Mutia; Asni, Enikarmila; Indrayana, Mohammad Tegar
Jurnal Online Mahasiswa (JOM) Bidang Kedokteran Vol 3, No 1 (2016): Wisuda Februari 2016
Publisher : Jurnal Online Mahasiswa (JOM) Bidang Kedokteran

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ABSTRACTIn the criminals like murder, torture, and rape usually found bloodstains, blood, sperm, saliva, and hair at the criminals scene. In the some forensic examination of blood are confirmatory test (Teichmann test and Takayama test) that can confirm if suspected object were blood. The way in which often wipe out blood using solid antiseptic bath soap. The purpose of this research was to know description of hemoglobin crystal on bloodstains that exposed by solid antiseptic bath soap with Teichmann test and Takayama test. The design of this research was experimental. Samples of this research were 26 bloodstains slides (2 control slides and 24 slides that have been exposed with 6 kind of solid antiseptic bath soap). The showed 24 bloodstains slides (100%) had positive result with Teichmann test and Takayama test, and there were no changes of crystal’s shape. It could be conclude that hemoglobin crystals still could be found in bloodstains that exposed by solid antiseptic bath soap with Teichmann test and Takayama test.Keywords: Hemoglobin crystals, Bloodstains, Solid antiseptic bath soap, Teichmann test, Takayama test
Pengaruh Air Perasan Umbi Bawang Merah (Allium ascalonicum L.) terhadap Malondialdehid (MDA) Plasma Mencit yang diinduksi Hiperkolesterolemia Ismawati, Ismawati; Asni, Enikarmila; Hamidy, M Yulis
Jurnal Natur Indonesia Vol 14, No 1 (2012)
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat Universitas Riau

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Abstract

Malondialdehyde, a product of lipid peroxidation, is often used as an indicator to detect the oxidative stress damaged in the body. Lipidperoxidation is associated with progression of atherosclerosis. It is known that onion (Allium ascalonicum L.) can be used as an antioxidantand hypolipidemic agent, but whether onion can decrease hypercolesterolemia mice MDA plasma induced by yolk is still unknown. Thepurpose of this study was to investigate the effect of onion’s juice on hypercolesterolemia mice MDA plasma level. This was an experimentallaboratory research with post test only design with control. The measured parameters were cholesterol and MDA level on tested groups.Groups with treatment consist of yolks group, and 80% shallot juice, simvastatin and aquadest were separately used as positive and negativecontrol. The result showed that there was significant difference between high fat feed group which added 80% onion’s juice and high fat feedgroup only. Addition of 80% onion’s juice in high fat feed groups decreased MDA plasma level equal to normal feed group. In conclusion, itwas proved that onion’s juice decreased mice MDA plasma level.
Co-Authors Fanny Pratiwi, Fanny Fatya Welinsa Fridayenti " Ismawati " Ismawati Ismawati M Yulis Hamidy Mohammad Tegar Indrayana Mutia Umara, Mutia Nurfi Pratiwi, Nurfi Viras Vitriani, Viras Welly N Pangaribuan Yessi Gusvita Sari Zulkifli Malik