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Bambang Madiyono
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Uji Fungsi Paru pada Anak Jalanan di Wilayah Jakarta Pusat Mohammad Muchlis; Mardjanis Said; Bambang Madiyono
Sari Pediatri Vol 7, No 3 (2005)
Publisher : Badan Penerbit Ikatan Dokter Anak Indonesia (BP-IDAI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/sp7.3.2005.169-76

Abstract

Latar belakang. Anak jalanan merupakan kelompok anak dengan risiko tinggi terhadapancaman maupun gangguan kesehatan. Kebiasaan beraktivitas sehari-hari membuat anakjalanan sering terpapar dengan polutan udara di jalan dan juga kebiasaan hidup yang tidaksehat seperti merokok membuat anak jalanan berisiko mengalami penurunan fungsi paru.Tujuan penelitian. Untuk mendapatkan gambaran nilai faal paru anak jalanan sebagaikelompok yang berisiko tinggi akibat pencemaran udara dan faktor-faktor yangmempengaruhinya.Metoda. Desain cross sectional terhadap kelompok anak jalanan di wilayah Jakarta Pusatyang dibina di empat rumah singgah. Pada subyek penelitian yang memenuhi kriteria inklusidilakukan pendataan riwayat pribadi dan penyakit, pemeriksaan fisik serta pengukuran nilaiarus puncak ekspirasi (APE). Subyek dipilih secara stratified random sampling dengan besarsampel ditentukan secara proporsional dan penghitungan untuk mencari koefisien korelasi.Hasil. Telah dilakukan pemeriksaan dan pengukuran nilai APE dengan alat mini wright peakflowmeter (MWPFM) terhadap 99 anak jalanan yang terdiri dari 61 anak laki-laki dan 38anak perempuan. Rentang usia terbanyak laki-laki 13-15 tahun, perempuan 7-12 tahun, 73masih bersekolah dan 26 anak putus sekolah. Dengan kuesioner international study of asthmaallergic in childhood (ISAAC) didapatkan 2 anak dengan riwayat pernah menderita asma.Status gizi anak jalanan menunjukkan 69 anak (70%) dengan gizi baik, 27 anak ( 27%) dengangizi kurang, dan 3 anak (3%) bergizi lebih. Kebiasaan merokok pada anak jalanan banyakditemukan pada kelompok anak laki-laki, yaitu pada kelompok usia 13-15 tahun 9 orang(26%), 16-18 tahun 4 orang (50%) dan 1 orang anak perempuan usia 17 tahun. Kelompokusia terbanyak menunjukkan kelompok usia sekolah tingkat SMP dan SMA.Kesimpulan. Nilai APE pada kelompok anak jalanan dipengaruhi oleh beberapa faktorantara lain jenis kelamin, umur, tinggi badan, berat badan dan luas pemukaan tubuh. NilaiAPE pada anak jalanan laki-laki sebagian besar berada di bawah nilai rata-rata menurutnomogram Godfrey; pada anak perempuan relatif sama baik untuk nilai di atas rata-ratamaupun di bawah rata-rata. Nilai APE pada anak jalanan tidak jelas berhubungan denganlama paparan, namun nilai indeks APE pada kelompok dengan paparan lebih dari 5 tahundan terpapar lebih dari 5 jam sehari cenderung lebih rendah dibandingkan kelompok anakjalanan yang lain. Nilai APE anak jalanan yang merokok tidak lebih rendah dari pada nilaitersebut pada anak jalanan yang tidak merokok.
Blood nickel level and its toxic effect after transcatheter closure of persistent duct arteriosus using Amplatzer duct occluder Mulyadi M. Djer; Bambang Madiyono
Paediatrica Indonesiana Vol 49 No 1 (2009): January 2009
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (113.217 KB) | DOI: 10.14238/pi49.1.2009.33-8

Abstract

Background  Transcatheter closure using amplatzer  duct  occluder(ADO)  is  currently the  treatment  of  choice for  patent  ductusarteriosus (PDA).  The  ADO  device  is  constructed from a Nitinolwire mesh containing 55% nickel. Up  to  now, there  is  still acontroversy about the effects  of  nickel contained in ADO.Objectives  To  determine blood nickel level  at  six months aftertranscatheter closure  of  PDA  using  ADO,  toxic effects  of  nickelat six months after  PDA  closure using  ADO,  and the effects  ofnickel  on  complete blood  count  (CBC), blood glucose and renalfunction.Methods  Subjects  were  patients  with  PDA  at  IntegratedCardiovascular Services,  Dr.  Cipto Mangunkusumo Hospital,Jakarta. Routine blood test and blood nickel levels were measuredat  the time  of  the procedure,  and  at  the  end  of  the first, third,  andsixth months after intervention.Results  There  were  29  patients who underwent heart catheteri-zation  and  PDA closure using  ADO.  A time series analysis wasconducted  on  23  patients who completed six-month follow-upafter the intervention. Median blood nickel level before procedurewas 58 ng/mL while  at  one, three  and  six months afterwards were60, 63 and 64 ng/mL respectively.  The  blood nickel levels didnot  differ significantly between pre- and  post-ADO. After  PDAclosure,  no  toxic effects  of  nickel were found,  both  clinically andlaboratorically.Conclusions  PDA  closure using  ADO  has no effects  on  the nickellevels, CBC, blood glucose and renal function;
Relationship between lipid profiles with carotid intima--media thickness in children with type I diabetes mellitus Rubiana Sukardi; Bambang Madiyono; Sudigdo Sastroasmoro; Jose RL Batubara
Paediatrica Indonesiana Vol 48 No 3 (2008): May 2008
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (251.541 KB) | DOI: 10.14238/pi48.3.2008.147-51

Abstract

Background The major cause of morbidity and mortality inpatients with type I diabetes mellitus is premature and extensiveartherosclerosis. Carotid intima-media thickness (IMT) isassociated with cardivascular risk factors and has been used as amarker of early artherosclerosis process.Objective To determine IMT of carotid artery and its relationshipwith duration of diabetes, lipid profiles, and mean HbA 1 level.Methods A cross-sectional study was conducted on patientswith type 1 DM at the Department of Child Health CiptoMangunkusumo Hospital. Ultrasound B-mode imaging wasperformed to measure the IMT. Age-matched non-diabteticsubjects served as controls. Statistical significant was assumedat P<O.S.Results The mean IMT values of type I DM patients aged < 12years, 12-18 years, 18+ years were 0.44 (SD 0.03) mm; 0.46(SD 0.01) mm; 0.51 (SD 0.01) mm, respectively, which weresignificantly greater than those of age-matched non-diabeticsubjects which were 0.39 (SD 0.01), 0.41 (SD 0.01) mm, 0.46(SD 0.01) mm, respectively. Patients with type I DM had ahigher apolipoprotein-Band HDL cholesterol levels than in non-diabetic subjects. Multiple regression analysis showed that therewas no relationship between total cholesterol, cholesterol LDL,chronic hyperglycemia (HbA 1) and IMT. However, IMT in typeI diabetes was linearly related with duration of diabetes .Conclusion Type I DM patients have greater IMT and highermean apolipoprotein B. There is a strong correlation betweenIMT and duration of diabetes.
Comparison of minimal inhibitory and bactericidal capacity of oral penicillin V with benzathine penicillin G to Streptococcus beta--hemolyticus group A in children with rheumatic heart disease Burhanuddin Iskandar; Bambang Madiyono; Sudigdo Sastroasmoro; Sukman T. Putra; Mulyadi M. Djer; Anis Karuniawati
Paediatrica Indonesiana Vol 48 No 3 (2008): May 2008
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (233.281 KB) | DOI: 10.14238/pi48.3.2008.152-5

Abstract

Background Injection ofbenzatine penicillin G (BPG) every 28days is still the drug of choice for secondary prevention of rheu-matic heart disease (RHD). BPG sometimes poses problems dueto pain at the injection site, possible anaphylaxis, and is not alwaysavailable. Some centers choose oral penicillin over BPG.Objectives To compare minimal inhibitory capacity (MIC) andminimal bactericidal capacity (MBC) of oral penicillin V serumwith those of BPG among SGA infected RHD.Methods This was a clinical trial with crossover design study tocompare MIC of penicillin V and BPG. Outcome measures wereMIC and MBC. Statistical analysis was performed using pairedt-test and wilcoxon test.Result There were 32 subjects consisted of 17 males and 15females. The mean value of MIC and MBC serum of penicillinV were 0.031 and 0.125. The mean value of MIC and MBCserum of BPG3 were 0.094 and 0.031. Respectively the MICof penicillin V was similar to that of BPGy The mean value ofMIC and MBC of BPG4 were 0.125 and 0.250. Respectively theMIC of penicillin V was significantly higher than that of BPG 4.The MBC of penicillin V was significantly higher than that ofBPG 4. The MIC ofBPG 3 was similar to that ofBPG 4• The MBCof BPG 3 was similar to that of BPG 4.Conclusions The MIC of penicillin V was similar to that ofBPG 3,the MBC of oral penicillin V was higher than that ofBPG 3• TheMIC and MBC of penicillin V was higher than those of BPG 4.
Effect of inhaled procaterol and budesonide on right ventricular diastolic function in children with asthma Alit Utamayasa; Najib Advani; Imam Boediman; Sudigdo Sastroasmoro; Bambang Madiyono
Paediatrica Indonesiana Vol 49 No 3 (2009): May 2009
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (142.917 KB) | DOI: 10.14238/pi49.3.2009.131-4

Abstract

Objectives To study changes in parameters of right ventricular(RV) diastolic function after procaterol and budesonide inhalationin children with asthma.Methods This was a one-group pretest-posttest design to determinechanges in right ventricular diastolic function followingfour weeks of inhaled procaterol and budesonide administration.Subjects were children aged 8 to 18 years with frequent episodicasthma recruited consecutively at the Department of ChildHealth, Cipto Mangunkusumo Hospital. M-mode and 2-Dechocardiography examinations were performed to determine RVisovolumetric relaxation time (IVRT), acceleration time (AT),deceleration time (DT), E wave, A wave, E/ A ratio, and tricuspidannular plane systolic excursion (TAPSE). Means of the RVfunction parameters before and after treatment were comparedusing the paired t-test or Wilcoxon test.Results There were 29 patients comprising 16 boys and 13 girls. Themeans or medians of theE wave, A wave, E/A ratio, accelerationtime (AT), deceleration time (DT), and isovolumetric relaxationtime (IVRT) before and after treatment were 0.55 and 0.55 em/sec(P=0.709), 0.45 and 0.35 em/sec (P<O.OOOl), 1.17 and 1.58 em/sec(P<0.0001), 52.73 and 55.03 m/sec (P=0.04), 55.39 and 58.10 m/sec (P=0.03), and 46.50 and 70.0 m/sec (P<0.0001), respectively.The median pre- and post-inhalation TAPSE were 1.63 and 1.84em, respectively (P<0.001).Conclusions In children with frequent episodic asthma, thereare changes in RV diastolic functions IVRT, AT, DT, E/A ratioand A wave following procaterol and budesonide inhalation.There was no increase in E wave following inhalation. TAPSEwas increased following procaterol and budesonide inhalation.
Inhibiting ability of benzathine penicillin G towards group A Streptococcus β -hemolyticus in 21 and 28 days after a single intramuscular injection Bambang Madiyono; Mulyadi M Djer; Sudigdo Sastroasmoro; Amin Subandrio; Erni Erfan
Paediatrica Indonesiana Vol 43 No 4 (2003): July 2003
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (301.249 KB) | DOI: 10.14238/pi43.4.2003.136-9

Abstract

Background The effectiveness of a single intramuscularbenzathine penicillin G as a secondary prevention of acute rheu-matic fever after 28 days is still controversial. The latest studyshowed that serum penicillin concentration was below protectivelevel in 4 weeks after a single intramuscular injection.Objective This study was a preliminary study to compare the in-hibiting ability of benzathine penicillin G towards group A Strepto-coccus β -hemolyticus in 21 and 28 days after a single IM injectionby using Mueller-Hinton broth method.Methods The inhibiting ability was measured by the serum in-hibitory concentration and serum bactericidal concentration aftera single intramuscular injection of benzathine penicillin G 1.2 mil-lion units.Results The subjects were 28 patients, with mean age of 15.5years (SD 3.4). The numbers of male and female were equal. Meanserum inhibitory concentration in 21 days after a single injectionwas 926.4 (SD 3080.1) and after 28 days was 1540.9 (SD 4275.1),which was not significantly different (p=0.0662). Mean serum bac-tericidal concentration in 21 days after IM injection was 1579.6(SD 4265.7) and in 28 days was 2417 (SD 6849.4) and it was notstatistically different (p=0.2276).Conclusion This study concluded that there was no significantdifference in the inhibiting ability of benzathine penicillin G to-wards group A Streptococcus β -hemolyticus between 21 and 28days after a single intramuscular injection
Comparison of continuous infusion and bolus administration of tramadol in postoperative children Jeanne-Roos Tikoalu; Darlan Darwis; Bambang Madiyono
Paediatrica Indonesiana Vol 43 No 5 (2003): September 2003
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (393.351 KB) | DOI: 10.14238/pi43.5.2003.165-70

Abstract

Objective To appraise the efficacy of tramadol therapy given bycontinuous infusion and bolus in handling child’s postoperative painthat is mostly inadequate.Methods This was a randomized, single-blinded clinical trial withparallel design. The study was done in the operation room, recov-ery room, pediatric intensive care unit, pediatric surgery, and pedi-atric ward of Cipto Mangunkusumo Hospital, Jakarta, Indonesia.There were sixty patients, 1-12 year-old, with elective operationbetween January and April 2002. Both groups received bolus of2mg/kg tramadol as an initial dose. Twenty-nine subjects receivedcontinuous infusion of 0.22 mg/kg/h tramadol in 15 minutes after-wards. The other 31 subjects received the same boluses for every6 hours. Before each tramadol administration, evaluation was doneby observer using objective pain scale (OPS) and evaluation sheetthat had been tested before the study. The study was done within24 hours post surgery.Results In the first 6 postoperative hours, mean total dose givenby continuous infusion was significantly greater than that given bybolus (p=0.006). On the contrary, mean total dose given within 24hours by continuous infusion was significantly less than that givenby bolus (p=0.037). All subjects showed OPS result of 36 in 0 minute.After that, the result decreased, except in 9 subjects it was still >6in the 15 th minute. Vomiting was the commonest side effect.Conclusion Continuous infusion of tramadol within 24 hours canbe recommended as an analgesic in postoperative children
Clinical manifestations of childhood asthma persisting until the age of seven Rini Asterina; Sjawitri P Siregar; Bambang Madiyono; Bambang Supriyatno
Paediatrica Indonesiana Vol 44 No 1 (2004): January 2004
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (368.738 KB) | DOI: 10.14238/pi44.1.2004.1-6

Abstract

Background Asthma is a chronic illness commonly found in chil-dren. We aimed to find out the clinical manifestations of childhoodasthma persisting until the age of seven and the influencing factors.Methods A review was performed at the outpatient clinic of theDepartment of Child Health Cipto Mangunkusumo Hospital Jakarta,from January 1992 to December 2001, on children with asthmawho still had symptoms until the age of seven.Results During the period of 10 years, there were 322 childrenwith clinical symptoms of asthma persisting until the age of 7. Onehundred and forty-six (45.3%) met the inclusion criteria, consistingof 75 (51.4%) boys and 71 (48.6%) girls. The average age was11.7 years. There were 101 (69.2%) patients with rare episodicasthma, 26.0% with frequent episodic asthma, and 4.8% with per-sistent asthma. Age of onset was mostly beyond 3 year-old (51%).Besides asthma, atopic diseases noted in these patients were al-lergic rhinitis in 85 (58.2%) and atopic dermatitis in 42 (28.8%).Logistic regression found that cigarette smoke exposure (adjustedOR 4.72, 95%CI 2.05;10.87, p=0.000), allergic rhinitis (adjustedOR 3.44, 95%CI 1.40;8.45, p=0.007), and atopic dermatitis (ad-justed OR 2.37, 95%CI 1.01;5.72, p=0.048) had significant asso-ciation with the degree of asthma.Conclusion Of 146 children who still had asthma until the age ofseven, there were 69% with rare episodic asthma, 26% with fre-quent episodic asthma, and 4.8% with persistent asthma. Factorspresumably influencing this manifestations were cigarette smokeexposure, allergic rhinitis, and atopic dermatitis
Stent implantation into ductus arteriosus: a new alternative of palliative treatment of duct-dependent pulmonary circulation Mulyadi M Djer; Bambang Madiyono; Sudigdo Sastroasmoro; Sukman T Putra; Ismet N Oesman; Najib Advani; Mazeni Alwi
Paediatrica Indonesiana Vol 44 No 1 (2004): January 2004
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (544.032 KB) | DOI: 10.14238/pi44.1.2004.30-6

Abstract

Background The technical aspects of ductal stenting have beenreported, but little is known about the fate of the duct after stentimplantation.Objectives To determine the effects of PDA stenting on the degreeof cyanosis, blood oxygen saturation, long-term patency of PDA,and the growth of pulmonary artery and its branches, in patientswith duct-dependent pulmonary circulation.Methods This was a case series study conducted at the Depart-ment of Pediatric Cardiology, Institut Jantung Negara (National HeartInstitute), Kuala Lumpur, Malaysia from November 1996 to Septem-ber 2001 on patients with duct-dependent pulmonary circulation whounderwent stent implantation. All patients were followed-up until oc-clusion or block occurred or until the end of follow-up time. The evalu-ation consisted of clinical manifestations, electrocardiography, chestx-ray, echocardiography, and cardiac catheterization.Results Stent was successfully implanted in 60 patients (84%),failed in 7 patients (10%) and contra indicated in 4 patients (6%).There was significant improvement on the degree of cyanosis afterstent implantation (p<0.0001). The blood oxygen saturation signifi-cantly increased from 74% (ranged 42-93; SD 12) before proce-dure, to 90% (ranged 62-100; SD 8) afterward (p<0.0001). The meanduration of follow-up time was 14.2 months (ranged 2.5-50.8; SD13) and the minimal patency of PDA was 11.2 months (ranged 1.1-47.7; SD 10.7) after implantation. At the end of follow-up, the stentswere widely patent in 33 patients (55%), stenotic in 15 patients (25%)and spontaneously occluded in 12 patients (20%). There was in-creased growth of pulmonary artery as measured by McGoon ratiofrom 1.23 (ranged 0.4-2.3; SD 0.4) to 1.81 (ranged 0.7-0.9; SD 0.57),and no distortion of pulmonary artery and its branches found.Conclusion Stent implantation into ductus arteriosus decreasedthe degree of cyanosis, increased blood oxygen saturation, main-tained long-term patency of ductus arteriosus, and promoted theincreased growth of pulmonary artery without distortion of pulmo-nary artery and its branches
Behavior and emotional problems in children with mental retardation Soedjatmiko Soedjatmiko; Muzal Kadim; Bambang Madiyono; Mardjanis Said
Paediatrica Indonesiana Vol 44 No 3 (2004): May 2004
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (311.011 KB) | DOI: 10.14238/pi44.3.2004.90-4

Abstract

Background Behavior and emotional problems in a mentally re-tarded child can inhibit the educational process of the child.Objectives The aims of this study were to find out the prevalenceof behavior and emotional problems in children with mental retar-dation as reported by parents and to assess associated risk fac-tors consisting of mother’s psychopathology, marital discord, malesex, child’s age, socioeconomic status, and family size.Methods This cross sectional study was carried out on 63 chil-dren with mental retardation in a school for retarded children, SLBC Asih Budi I, from January until March 2003. Parents were inter-viewed at school and home using special questionnaires, the ChildBehavior Checklist (CBCL) and Symptom Checklist-90 (SCL-90).Results The prevalence of behavior and emotional problems inthis study was 52%. The majority of behavior and emotional prob-lems were anxious/depressed (18%) and withdrawn (16%). Malesex and age group of 12-18 year-old were not risk factors of be-havior and emotional problems (OR=0.49, p=0.190 and OR=1.14,p=0.94, respectively) while socioeconomic status, family size, andmother’s psychopathology were risk factors (OR= 4.08, p=0.008;OR=4.17, p=0.014; OR=9.28, p=0.018; respectively). There wasa correlation between behavior and emotional problems of chil-dren and marital discord.Conclusion The prevalence of behavior and emotional problemswas 52% in which the majority was internalizing disorder. Risk fac-tors for behavior and emotional problems were mother’s psycho-pathology, four or more children in the family, low socioeconomicstatus, and marital discord
Co-Authors Abdul Latief Agus Firmansyah Alan Roland Tumbelaka Alit Utamayasa Amin Subandrio ANIS KARUNIAWATI Bambang Supriyatno Bulan Ginting Munthe Burhanuddin Iskandar Damayanti R Sjarif Darlan Darwis Djajadiman Gatot Dwi Putro Widodo Edi S Tehuteru Erni Erfan, Erni Hariarti S. Pramulyo Hartono Gunardi Imam Boediman Indra Sugiarno Ismet N Oesman Jeanne-Roos Tikoalu Jose RL Batubara Luszy Arijanty Mardjanis Said Mardjanis Said Mazeni Alwi Mohammad Muchlis Mulyadi M Djer Mulyadi M. Djer Mururul Aisyi Muzal Kadim Najib Advani Ria Nova Rini Asterina Rini Sunarwati Rosdiana S Tarigan Rubiana Sukardi Sander D Teddy Sjawitri P Siregar Soedjatmiko Soedjatmiko Sri Sudaryati Nasar Sudigdo Sastroasmoro Sukman T Putra Sukman T. Putra Titis Prawitasari Widhodho T. Karyomanggolo Willy Edith HP