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The Comparison of Gabapentin and Amitriptilin Effectivity as Pain Therapy in Herniated Nucleus Pulposus Indriastuti Cahyaningsih; Rina Handayani; Setyaningsih Setyaningsih
International Journal of Public Health Science (IJPHS) Vol 4, No 3: September 2015
Publisher : Intelektual Pustaka Media Utama

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (143.571 KB) | DOI: 10.11591/ijphs.v4i3.4738

Abstract

Herniated nucleus pulposus (HNP) is one of peripheral neuropathic pain. Although concensus guidelines for the treatment of neuropathic pain are based on the results of the RCT studies, there are still gaps in the literatures. This study aimed to compare the effectiveness and quality of life of gabapentin and amitriptyline for the treatment of pain in HNP. The method used a quasi experimental with consequtive sampling. This study included 30 patients in the gabapentin group and 26 patients in the amitriptyline group, and each group was evaluated for 1 month. Effectiveness was assessed using Visual Analogue Scale (VAS) every 2 weeks then analized by independent and paired sample t test. The results showed that the use of gabapentin and amitriptilin in 4 weeks showed the decrease of pain score measured by visual analog scale 3.70 ± 0.349 and 3.500 ± 0.34 although there was no statistical difference (p value = 0.704). To sum up, effectiveness of gabapentin and amitriptyline in the treatment of neuropathic pain did not have statistical difference.
PENGARUH KONSELING APOTEKER TERHADAP TINGKAT KEPATUHAN DAN HASIL TERAPI PASIEN HIPERTENSI RAWAT JALAN DI POLIKLINIK PENYAKIT DALAM Yosi Febrianti; Satibi Satibi; Rina Handayani
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 3, No 4
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.248

Abstract

Pemberian konseling yang tepat dan bermanfaat diharapkan dapat meningkatkan kepatuhan terhadap terapi obat untuk mencapai tekanan darah yang diinginkan. Tujuan penelitian ini untuk mengetahui pengaruh pemberian konseling terhadap tingkat kepatuhan  dan hasil terapi serta mengetahui hubungan tingkat kepatuhan dan hasil terapi pasien hipertensi rawat jalan di di RSUD Sleman. Penelitian ini dilakukan dengan rencangan control group design with pretest posttest. Penelitian ini dilakukan pada 106 pasien yang terbagi secara random menjadi 2 kelompok yaitu 53 pasien pada kelompok kontrol dan 53 pasien pada kelompok perlakuan. Pada kelompok perlakuan, konseling diberikan 2 kali setiap 2 minggu . Penilaian kepatuhan dilakukan dengan menggunakan kuesioner MMAS (Morisky Medication Adherece Scale) pada kedua kelompok tersebut yaitu pada awal pasien rawat jalan dan 1 bulan setelah pemberian konseling. Kemudian nilai dari MMAS pada kedua kelompok akan dianalisis dengan Mann Whitney dan Wilcoxon karena data tidak terdistribusi normal serta diuji chi square dan spearman untuk mengetahui hubungan dari masing-masing kelompok. Hasil penelitian menunjukkan bahwa terjadi penurunan rerata tekanan darah bermakna pada kelompok perlakuan 19,2 poin (p=0,000) pada tekanan darah sistolik dan 6,03 poin (p=0,074) pada tekanan darah diastolik sedangkan pada kelompok kontrol tidak terdapat perubahan rerata yang bermakna. Hasil uji korelasi kepatuhan dan hasil terapi menunujukkan hubungan yang positif dan bermakna antara kategori MMAS dengan tekanan darah sistolik (p=0,000; r=0,725) dan tekanan darah diastolik (p=0,002; r=0,205). Penelitian ini menyimpulkan bahwa konseling dapat berpengaruh terhadap kepatuhan pasien sehingga dapat menurunkan tekanan darah sistolik dan diastolik pada kelompok perlakuan dibandingkan kelompok control. Kata kunci: konseling, apoteker, kepatuhan, tekanan darah
STRUKTUR DAN FUNGSI PANTUN DALAM ACARA MANYERAKAN MARAPULAI DAN ANAK DARO PADA UPACARA PERNIKAHAN DI DESA TABEK SIRAH KABUPATEN PASAMAN BARAT Rina Handayani; Agustina Agustina; Hamidin Hamidin
Jurnal Bahasa dan Sastra Vol 2, No 2 (2014): SERI B
Publisher : Faculty of Languages and Arts, Universitas Negeri Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24036/833590

Abstract

The purpose of this study was to describe the structure and function of the poem in the event manyerakan marapulai and children daro at the wedding ceremony in the village of West Pasaman Tabek Sirah. This research is descriptive qualitative research method. The object of research in the form of rhymes and children's events manyerakan marapulai and children daro. Data analysis was performed with (1) transcripts of recording data into written language, (2) analyzing the data, (3) to classify the data into the aspects studied, (4) interpreting the data in accordance with the purposes of the study, (5) make the conclusion. The results of this study indicate that in the event manyerakan marapulai rhymes and children daro has a physical structure and inner structure. The physical structure consists of : diction, imagery, concrete words, figurative language, rhyme and Rithmah, while the inner structure consists of : theme, feeling, tone and atmosphere and mandate. Functions contained in the event manyerakan marapulai rhymes and children daro found ten functions, namely (1) as a means of communication, (2) the identity, (3) as an ornamental flower oral tradition, (4) as a means to preach, (5) as a means to educate, (6) as the embodiment of indigenou , (7) as a means of entertainment, (8) as symbols of culture, (9) evokes heroic values ​​and (10) to further humanize humans.