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Journal : Indian Journal of Forensic Medicine

Effect of Non-Computerized Cognitive Remediation and Risperidone to Improve Disability Function in Schizophrenia Sonny T. Lisal; Saidah Syamsuddin; Anisa
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14441

Abstract

The aim of the study was to find out the effect of non-computerized cognitive remediation and risperidonetherapy to improve cognitive function and disability condition in schizophrenia patients. This study was anexperimental research design, with fourteen participants divided into two group as the experimental groupand the control group. The experimental and control groups both received Risperidone. In addition, theexperimental group was given the non-computerized cognitive remediation (CR). The non-computerizedcognitive remediation will be carried out in 12 sessions (3 sessions per week) using mainly paper andpencil tasks and is based on cognitive strategy instruction. Moreover, all samples will be measured forPANSS (Positive and Negative Symptom Scale), WHODAS 2.0 (World Health Organization DisabilityAssessment Schedule), and SCoRS Vi (Schizophrenia Cognition Rating Scales Indonesian Version) scores.As the results, both experimental and control group showed a significant decrease in the SCoRS Vi andWHODAS 2.0 score (p=0.001). However, the experimental group showed greater improvement comparedto the control group. Synergistic effect of Non-computerized Cognitive Remediation and Risperidone canimprove disability condition in schizophrenia patients.
The Influence of Fluoxetine Therapy Combination of Rational Emotive Behaviour Therapy Againts the Improvement of Depression Symptoms, Cognition Function and Improvement of Brain-Derived Neurotrophic Factors Serum Levels in Patients with Depressive Veraferial Muchtar; Erlyn Limoa; Nur Aeni M.A. Fattah; Andi Alfian Zainuddin; Ika Yustisia; Saidah Syamsuddin; Sonny Teddy Lisal
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.15110

Abstract

Introduction: Depression is a health problem in the world that has affected more than 300 million peoplearound the globe. This health problem is characterized by feeling sad, depressed, irritability as well asdistortion of cognition such as self-criticism, feeling of guilt, feeling of worthlessness, lower self-confidence,pessimism and hopelessness where their manifestations may vary for each individual. Method: In this study,it compares the fluoxetine group combination of Rational Emotive Behavior Therapy (REBT) with thefluoxetine group in the treatment of reducing symptoms of depression and improving cognitive function.This research is an experimental research with pre-test and post-test control group design. The samplingtechnique was done by using consecutive sampling for each group. Results: From the results of the studyit was found that the mean of Hamilton Depression Rating Scale (HDRS), the Indonesian version of theMontreal Cognitive Assessment (MoCA-Ina) and Brain-Derived Neurotrophic Factor (BDNF) serum levelsin the samples given by both groups experienced statistically improvements. Conclusion: there is an effecton the provision of fluoxetine therapy combination of REBT compared to fluoxetine therapy alone inimproving depressive symptoms, cognitive function as well as increasing BDNF serum levels.