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All Journal Indian Journal of Forensic Medicine & Toxicology
Mohammad Fathul Qorib
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Public Health

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The Effects of Turmeric Extract (Curcuma longa) Loaded Hidrogels in Accelerating Wound Closure David Setyo Budi; Reny I`tishom; Alphania Rahniayu; Mohammad Fathul Qorib
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14699

Abstract

Background: Disruption to healing process results on longer healing duration from the timeline. Povidoneiodine and tulle are common management in wound care. The advance of industry in health sector andthe availability of natural ingredients in Indonesia provide opportunities for developing alternatives forwound care. Turmeric (Curcuma longa) contains curcumin which is anti-inflammatory, antibacterial,and antioxidant; it is good for wound healing. Hydrogel nanocomplexes of carboxymethyl chitosan canmaintain moisture in wound area and protect curcumin from hydrolysis. Objective: To analyze the potentialof turmeric extract loaded hidrogels in accelerating wound closur. Method: experimental research with“post-test only control group design”. The sample consisted of 30 mice which were assigned into 5 groups.Result: All experimental groups experienced a gradual decrease in wound length. The statistical test resultsfor groups II and III showed significant advantages compared to group IV (p<0.05). Meanwhile, group Idid not have significant differences in wound closure compared to group IV on day 1 and 3 (p>0.05), but ithad significant results (p<0.05) on day 5. Conclusion: Turmeric extract loaded hidrogels can accelerate thereduction of wound length.
Co-Authors Alphania Rahniayu David Setyo Budi I'tishom, Reny