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IDENTIFIKASI Candida sp DALAM URINE PENDERITA DIABETES MELLITUS TIPE 2 DI PUSKESMAS NGEMPLAK 2 KABUPATEN SLEMAN YOGYAKARTA Farida Muhajir, Nurlaili; Nadifah, Fitri; Arisandi, Desto; Susliyanti, Maria
Jurnal Mitra Kesehatan Vol. 3 No. 1 (2020): Jurnal Mitra Kesehatan
Publisher : STIKes Mitra Keluarga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47522/jmk.v3i1.50

Abstract

Pendahuluan: Jamur Candida sp dapat berperan sebagai mikroorganisme yang bersifat patogen yaitu menimbulkan infeksi primer dan sekunder. Penderita diabetes mellitus (DM) dapat mengalami infeksi jamur tersebut karena mekanisme pertahanan alami tubuh yang rendah. Komplikasi yang terkait DM dapat meningkatkan risiko infeksi, peningkatan kadar gula dalam darah, jaringan, dan urine. Penelitian ini bertujuan untuk mengetahui keberadaan jamur Candida sp dalam urine penderita diabetes mellitus tipe 2. Metode Jenis penelitian ini adalah deskriptif dengan desain penelitian cross sectional. Jumlah sampel sebanyak 30 spesimen urine penderita diabetes mellitus tipe 2 dengan kriteria inklusi berjenis kelamin laki-laki dan perempuan, pasien adalah peserta program pengelolaan penyakit kronis (prolanis) di Puskesmas Ngemplak 2 Kabupaten Sleman Yogyakarta. Tahap pengumpulan data dilakukan pada bulan Juli 2019 di Puskesmas Ngemplak 2 Kabupaten Sleman Yogyakarta. Pemeriksaan jamur Candida sp dilakukan secara makroskopis dan mikroskopis. Hasil: Hasil penelitian menunjukkan sebanyak 8 sampel (26,7%) ditemukan jamur Candida sp dan 22 sampel (73,3%) tidak ditemukan jamur Candida sp. Sampel dengan jamur Candida sp, sebagian besar berasal dari penderita diabetes mellitus berjenis kelamin perempuan yaitu sebanyak 5 sampel (16,3%). Kesimpulan: Jamur Candida sp dapat ditemukan dalam urine penderita diabetes mellitus terutama penderita dengan jenis kelamin perempuan. Hal ini dapat disebabkan oleh kondisi sistem kekebalan tubuh menurun, atau sering menggunakan pakaian ketat dari bahan sintetis.
Pengaruh Pemberian Ekstrak Etanol Buah Sirsak (Annona muricata L.) Pada Kadar Kolesterol Low Density Lipoprotein (LDL) Tikus Putih (Rattus norvegicus) Hiperkolesterolemia Siti Fatimah; Desto Arisandi; Sismawati Sismawati
Biomedika Vol 12 No 2 (2019): Jurnal Biomedika
Publisher : Fakultas Ilmu Kesehatan Universitas Setia Budi Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (182.133 KB) | DOI: 10.31001/biomedika.v12i2.637

Abstract

The cause of Coronary heart disease is an increase caused due to increased cholesterol levels in the blood, so there is a risk of blockage in the blood vessels (atherosclerosis). LDL cholesterol which is abundant in the bloodstream will accumulate in the arteries and potentially cause blockages. Ethanol extract of soursop fruit (Annona Muricata L.) contains antioxidant compounds such as alkaloids, tannins, saponins, flavonoids and polyphenols that are needed to increase endurance and prevent various diseases that enter the body. Research has been conducted to determine the effect of soursop fruit ethanol extract (Annona Muricata L.) on Low Density Lipoprotein (LDL) cholesterol levels white Rat (Rattus Norvegicus) hipercolesterolemia. This research was conducted experimentally with 10 male white rats (Rattus Novergicus, L.), aged 2-3 months with a weight of 150-200 g, which were divided into 2 groups: the control group and the treatment group. Hypercholesterolemia induction is done by giving high fat diet foods for 7 days. Soursop fruit ethanol extract was given in a sonde to the treatment group at a dose of 3.6 mg / 200gBB / day for 14 days and measurements of LDL cholesterol levels were carried out on days 16 and 30 by the CHOD-PAP examination method. Data were analyzed by Paired t-test. The results showed LDL cholesterol levels in the treatment group showed that as many as 5 mice decreased, the mean decreased by 32.49 mg / dl while in the control group as many as 2 mice decreased, the mean decreased by 0.76 mg / dl. There was a significant difference (p <0.05) in changes in LDL cholesterol levels in the treatment group. Soursop fruit etanol extract with 3.6 mg / 200gBB / day for 14 days can reduce LDL cholesterol levels in hypercholesterolemia rats.
The association between demographic and attitude factors with the practice of malaria prevention among the rural community in Purworejo district, Indonesia Farindira Vesti Rahmasari; Winny Setyonugroho; I Ketut Swarjana; Desto Arisandi; Tri Wulandari Kesetyaningsih
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 5, No 1 (2021)
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v5i1.5416

Abstract

Abstract Malaria is one of the global health problems that is faced by many countries, including Indonesia. This study aimed to examine the association between demographic and attitude factors with malaria prevention in the rural areas of Purworejo District, Indonesia. A community survey was conducted in Purworejo District that involved 147 respondents by using simple random sampling to select the respondents. A questionnaire interview was used to collect data about demographic factors, attitudes, and malaria prevention practices. A Chi-square test was performed to examine the association between demographic and attitude factors with the practice of malaria prevention in the community. Among 147 respondents, 80 (54.4%) respondents conducted malaria prevention practice using bed mosquito net in their own houses. Demographic factors such as education level (p<0.001), occupation (p=0.016), and attitude factor (p=0.006) were significantly associated with the use of bed mosquito net for malaria prevention practice. Meanwhile, 63 (42.9%) respondents used ventilation mosquito net for malaria prevention practice. Demographic factors such as education level (p<0.001), age groups (p=0.005), occupation (p=0.002), and attitude factor (p=0.001) were associated significantly with the use of ventilation mosquito net for malaria prevention practice. Overall, malaria prevention by using both bed and ventilation mosquito nets were very low percentages. Keywords             : Malaria, prevention practice, mosquito net, IndonesiaCorrespondence   : farindira.vesti@gmail.com
IDENTIFIKASI LARVA NYAMUK PADA TEMPAT PENAMPUNGAN AIR DI PADUKUHAN DERO CONDONG CATUR KABUPATEN SLEMAN Fitri Nadifah; Nurlaili Farida Muhajir; Desto Arisandi; Maria D. Owa Lobo
Jurnal Kesehatan Masyarakat Andalas Vol 10, No 2 (2016): Jurnal Kesehatan Masyarakat Andalas
Publisher : Faculty of Public Health, Andalas University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24893/jkma.v10i2.203

Abstract

Penyakit menular yang disebabkan oleh vektor seperti demam berdarah   dengue,   malaria,   filariasis,   encephalitis,   masih   menjadi   masalah kesehatan masyarakat di dunia termasuk Indonesia. Demam berdarah dengue adalah penyakit yang disebabkan oleh virus Dengue yang ditularkan ke manusia melalui gigitan nyamuk Aedes sp yang terinfeksi virus Dengue. Nyamuk Aedes sp berkembangbiak di tempat-tempat penampungan   air   yang   mengandung   air   jernih   atau   air   yang   sedikit terkontaminasi.  Penelitian  ini  bertujuan  untuk  mengidentifikasi  jenis  larva nyamuk yang ditemukan di tempat penampungan air dan menghitung kepadatan larva nyamuk di RT 04 RW 15 Padukuhan  Dero, Desa Condongcatur. Jenis penelitian ini adalah deskriptif dan desain penelitian adalah Cross sectional.  Pengambilan sampel dilakukan di 50 rumah yang berada di RT 04 RW 15 Padukuhan Dero Desa Condongcatur. Hasil penelitian menunjukkan bahwa jenis larva nyamuk yang ditemukan di   tempat   penampungan   air   di   RT   04   RW   15   Padukuhan   Dero,   Desa Condongcatur adalah larva Aedes aegypti. Wilayah ini  berisiko tinggi untuk penularan DBD dengan kepadatan larva nyamuk masing-masing untuk House Index (HI) adalah 44%, Container Index (CI) adalah 17,8% dan Angka Bebas Jentik (ABJ) yang di bawah 95%, yaitu sebesar 56%. Kata Kunci: larva, nyamuk, penampungan air 
GAMBARAN FAKTOR RISIKO KEJADIAN HIPERGLIKEMIA PADA PRALANSIA DI DUSUN REJOSARI, KEMADANG, GUNUNG KIDUL, YOGYAKARTA Desto Arisandi; Maria Asih Triyanti; Nurlaili Farida Muhajir; Siti Fatimah
PROSIDING SEMINAR NASIONAL & INTERNASIONAL 2015: Prosiding Bidang MIPA dan Kesehatan The 2nd University Research Colloquium
Publisher : Universitas Muhammadiyah Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (240.556 KB)

Abstract

Background: Prevalence rate of diabetes mellitus based on clinical diagnose and symp had already reached out 63.6% in 2007 meanwhile that could be increased into 2.1% in 2013 in Indonesia and also that already happened in D.I Yogyakarta amount of 5.4%. Obesity took a part as one of the most important factor which might be caused diabetes mellitus with prevalence rate of 2.9 higher in overweight groups in Indonesia. Rejosari was the coast area which people took a job as fisherman largely and they inclined to take seafood as their meals which had high fat level. The research objectives were describing risk factors of hyperglycemia in middle age in Rejosari, Kemadang, Tanjung Sari, Gunung Kidul, Yogyakarta. Method: This was a descriptive study in middle age which took 60 people of amount as subjects. This carried on February 2015 in Rejosari, Kemadang, Tanjung Sari, Gunung Kidul, Yogyakarta. Data had been collected which were age, sex, diabetes mellitus history in family, education, smoking behavior, waist size measurement, body mass index (BMI) and blood glucose level. Data was analyzed as descriptive and showed in tables, percentages, and narration. Result: Among the 60 people who as subject, 67% of them got hyperglycemia. Hyperglycemia much happened to ≥ 55 years older age group as 73%, male as 71%, lower education level as 78%, having diabetes mellitus history in family as 63%, smoking behavior as 67%, unnormal waist size as 63% and obesity as 74%. Conclusion: Hyperglycemia much happened to ≥ 55 years older age group, male, lower education level, having diabetes mellitus history in family, smoking behavior, unnormal waist size and obesity.Kata Kunci: middle age, blood glucose, hyperglycemia
Perbedaan Kadar Asam Urat Sebelum dan Setelah Pemberian Jeroan pada Tikus Putih Desto Arisandi; Syeun Nurochman; Subrata Tri Widada
Journal of Health (JoH) Vol 2 No 1 (2015): Journal of Health - January 2015
Publisher : LPPM STIKES Guna Bangsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (305.742 KB) | DOI: 10.30590/vol2-no1-p33-36

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Background: The era of globalization has brought many changes to lifestyle and eating habits are not healthy in the community. High protein foods that contain lots of purines can cause hyperuricemia. The aim of this study was to determine differences in the uric acid levels of before and after given of offal in the mice. Method: A true experimental study with pretest-posttest control group design used 14 mice. Data collection from measurements in the uric acid levels in the blood of mice examined before and after given of offal chicken liver juice. Analysis of research data was used dependent of paired t-test with confidence level of 95% using SPSS. Result: An average uric acid level before gift of the offal is 3.41 mg/dL, and after to gift of the offal is 7.93 mg/dL. Uric acid levels after to given of offal increased by 4.52 mg/dL (56.99%). In analysis univariate showed differences between uric acid levels before and after to gift of offal chicken liver juice in the mice (p-value = 0.000). Conclusion: There are differences in uric acid levels before and after given of offal in the mice.
Persentase Pediculosis capitis pada Anak Usia 9-12 Tahun di RW XI Kampung Gampingan Kota Yogyakarta Nurlaili Farida Muhajir; Desto Arisandi; Yuliana Prasetyaningsih
Journal of Health (JoH) Vol 2 No 1 (2015): Journal of Health - January 2015
Publisher : LPPM STIKES Guna Bangsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (239.983 KB) | DOI: 10.30590/vol2-no1-p42-47

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Background : Pediculosis capitis disease can be found all over the world without the restrictions of age, gender, race, economic status, and social status. Pediculosis capitis mainly affects young children and quickly spread in a dense environment such as dorm, orphanages, large cities and densely populated elementary school with bad hygiene, such behavior is rarely clean the hair. Factors that can help spread Pediculus humanus capitis infestation is socio-economic factors, level of knowledge, personal hygiene, environment, and individual characteristics (age, hair length, and hair type). Methods : This was descriptive study. The population in this study was children who were stayed in kampung Gampingan kota Yoyakarta. Sample was taken by purposive sampling with criteria of inclusion and exclusion. The instrument used laboratory examination about Pediculus humanus capitis with direct examination. Analysis of data used univariate analysis. Result & Conclusion : Pediculosis capitis children who have age 9-12 years in Kampung Gampingan RW XI Yogyakarta was 86.84%.
Helminth Infection of Children in Ngemplak Seneng Village Klaten Fitri Nadifah; Desto Arisandi; Nurlaili Farida Muhajir
Journal of Health (JoH) Vol 3 No 1 (2016): Journal of Health - January 2016
Publisher : LPPM STIKES Guna Bangsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (166.553 KB) | DOI: 10.30590/vol3-no1-p14-18

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Helminth infection remains one of health problems of Indonesian people for years. The tropical condition of Indonesian climates with high level humidity has believed to be the one of factors that increase the number of this infection cases. Based of many studies, the number of helminth infections is related to the poor of hygiene and sanitation. This study is conducted to know the percentages of helminth infections among 0-14 years old children in Dusun Ngemplak, Desa Ngemplak Seneng, Klaten and also their personal hygiene with questionaire instruments. To know helminth infection in subjects, we examine faeces sample with simple method and 1% eosin dye. As the results of examination, we found Trichuris trichiura egg in three samples. This might related to the poor of their hygienic behaviors. Some of the behavior such as wash hand before eating and after defecation, use sandal or shoes when playing, consume helminthic drug for last 6 months, and defecate in toilet has shown percentage under 70%. Other behaviors such as cutting and cleaning nails and use a spoon when eating has shown percentage above 70%.
Identification of Malaria Parasites in Chasan Boesoirie General Hospital Ternate East Nusa Tenggara Desto Arisandi; Sofvirah R. Sohy; Fitri Nadifah
Journal of Health (JoH) Vol 3 No 1 (2016): Journal of Health - January 2016
Publisher : LPPM STIKES Guna Bangsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (241.014 KB) | DOI: 10.30590/vol3-no1-p39-44

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Background: Malaria is still a global health problem especially in tropical countries, such as Indonesia. Based on survey 35% of the Indonesia population were live in endemic areas of malaria, such as Provinces of Maluku, North Maluku, Papua, West Papua, North Sumatra, and East Nusa Tenggara. Malaria is caused by a mosquito bite of female Anopheles sp. containing Plasmodium parasite. Generally it bites humans at night or dawn. Such malaria parasites are Plasmodium falciparum, Plasmodium vivax, Plasmodium malariae, and Plasmodium ovale. Malaria is a disease of both highest in Ternate and mostly occur in general hospitals of Chasan Boesoirie General Hospital. This research aims to identify the type of malaria parasites in the Chasan Boesoirie General Hospital Ternate. Method: This is a descriptive research conducted in Chasan Boesoirie General Hospital in Ternate, East Nusa Tenggara in March 2015. Research data obtained include: age, sex, education, and employment. Identification of malaria is carried out based on an examination of the existence of Plasmodium in preparation of thin and thick blood apus. Descriptive analysis using STATA programs for Windows version 12.0 (Stata Corp LP., College Station, TX, USA) are presented in the form of tables and narratives. Result: This research subjects were 69 people suspected with malaria infection. Suspected malaria to be infected by Plasmodium is more are young age group 94%, 88% were males, 100% have a poor education or un-educated, as well as the of 100% were fishermen. As much as 54 people (78%) were infected by Plasmodium parasites consisting of Plasmodium falcifarum 48 people (89%) and Plasmodium vivax 6 people (11%). Conclusion: The incidence of malaria infections in Chasan Boesoirie General Hospital amounted to 78% and the type of infected parasites were Plasmodium falcifarum and Plasmodium vivax.
Potensi Infusa Daun Sirsak (Annona Muricata) Sebagai Daya Larvasida Larva Aedes aegypti Desto Arisandi; Maria Theresia Doe Bay; Nurlaili Farida Muhajir
Journal of Health (JoH) Vol 4 No 1 (2017): Journal of Health - January 2017
Publisher : LPPM STIKES Guna Bangsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (217.38 KB) | DOI: 10.30590/vol4-no1-p55-59

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Background: Dengue hemorrhagic fever (DHF) which is caused by dengue virus remains a global health problem that belongs to Indonesia also. Transmission works through the bite of female Aedes aegypti. An attempt is developing bioinsecticide with no harm which is involved to vector control such as leaves of the soursop (Annona muricata) that contains active substances such as saponins, tannins, and alkaloids that serves as larvicides. Aims: This research attempted to discover soursop leaves infuse with various concentrations served as larvacide to mortality of larva of A. aegypti. Method: This was a quasi-experimental research with posttest group design which conducted in parasitology laboratory of Poltekkes Kemenkes Yogyakarta. The subjects of research that infuse soursop leaves with a concentration of 15% and 20%, while the object of research is the number of deaths the third instar larvae of A. eagypti after addition of various concentrations of soursop leaf infusion. Result: Larvicidal activity test soursop leaf infusion using 15% concentration can kill larvae of A. aegypti by 75%, while 20% concentration can kill larvae of A. aegypti by 85%. Statistical analysis using ANOVA test is known that administration of soursop leaves infuse a significant influence against A. aegypti larvae mortality (p <0.001). Conclusion: Soursop leaves infuse with a concentration of 15% and 20% having a larvicidal activity of A. aegypti.