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Potency of Piper crocatum Decoction as an Antihiperglycemia in Rat Strain Sprague dawley MEGA SAFITHRI; FARAH FAHMA
HAYATI Journal of Biosciences Vol. 15 No. 1 (2008): March 2008
Publisher : Bogor Agricultural University, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (29.889 KB) | DOI: 10.4308/hjb.15.1.45

Abstract

Current researches for appropriate hypoglycemic agents focused on plants for traditional medicine. Traditionally in diabetic treatment, people used decoctions of Piper crocatum (Piperaceae). However, there is no phytochemical data of decoctions extract of P. crocatum. Hence, the aims of this study were to explore the phytochemical of P. crocatum decoctions and its antihyperglicemic activity. Fresh leaves of P. crocatum were boiled in water to obtain decoction and were examined phytochemical compounds by using Harbone assay. Antihyperglicemic activity of P. crocatum decoction extract was orally fed to alloxan induced diabetic rats. Results showed that P. crocatum decoction extract contained flavonoids, tanins, and alkaloids. Ten days of daily treatment of various doses decoction extract of P. crocatum led to reduce blood sugar level by 10-38% and prevent fall in body weight level by 5-52%. This result showed the same activity as Daonil treatment, which was the diabetic drug. Hence, this extract showed antihyperglicemic activity in alloxan-induced diabetic rats and increasing of their body weight. Key words: Piper crocatum, antihyperglicemic, phytochemical
ANALISIS PROKSIMAT DAN TOKSISITAS AKUT EKSTRAK DAUN SIRIH MERAH YANG BERPOTENSI SEBAGAI ANTIDIABETES Mega Safithri; Farah Fahma; Paramitha Wirdani Ningsih Marlina
Jurnal Gizi dan Pangan Vol. 7 No. 1 (2012)
Publisher : Food and Nutrition Society of Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (207.376 KB) | DOI: 10.25182/jgp.2012.7.1.43-49

Abstract

The aim of this study was to explore the analysis proximate and toxicity of the decoctions of P. crocatum. Fresh leaves of P. crocatum were boiled in water in order to obtain decoction and were examined for its chemical compounds by using SNI 01-2891-1992 method for proximate analysis. Toxicity of decoction extract of P. crocatum was orally fed to rats (Sprague dawley). The results showed that P. crocatum leaves contains 9.27% water, 14.33% ash, 3.96% fat, 22.63% proteins, and 59.08% carbohydrates. Acute toxicity test showed that all rats were still alive after 7 days treatment with P. crocatum decoction for all dose groups (0, 5, 10, and 20 g/kg BB). LC50 value of P. crocatum decoction was 544.82 ppm, meaning that the decoction was relatively harmless and bioactive.
PERMODELAN MATEMATIKA EKSTRAKSI OLEORESIN TEMULAWAK (Curcuma Xanthorrizha Roxb) DENGAN KARBONDIOKSIDA SUPERKRITIS DAN CO-SOLVENT ETANOL MENGGUNAKAN SHRINKING CORE MODEL Farah Fahma Dept. TIN
Jurnal Teknologi Industri Pertanian Vol. 16 No. 3 (2006): Jurnal Teknologi Industri Pertanian
Publisher : Department of Agroindustrial Technology, Bogor Agricultural University

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

AbstractThis experiment studied the extraction of oleoresin from Curcuma Xanthorrizha Roxb using supercritical carbon dioxide. Effects of various operation condition such as pressure, temperature, extractions time, and addition of ethanol-co-solvent into bulk carbon dioxide have been studied. Solubility of carbon dioxide could be increased by addition of co-solvent ethanol. Temperature and pressure affect solubility of oleoresin in carbon dioxide so that it may affect to oleoresin, and curcuminoid yield. Extraction temperature and pressure were performed at 45-65 oC and 10-18 MPa, respectively. Simulation study  that could describe the process of oleoresin extraction from Curcuma Xanthorhiza Roxb by supercritical carbon dioxide have been done using Shrinking Core Model. Fitting the calculated curve and experimental data done by trial the difference value of a and Bi, where a = (V/L) (R2/De) and Bi = (kf R/De). Effective inter particle diffusion value (De) and external mass transfer coefficient (kf) could be determined after trial value of a and Bi. At 14 Mpa, 50oC, with co-solvent, the resulted value of De is 6.572 x 10-11 and the value of kf is 1.2159 x 10-5 with error value 2.46 %. Keywords : modeling, supercritical carbon dioxide, Curcuma Xanthorrixa Roxb.
PENGGUNAAN METODE FMECA (FAILURE MODES EFFECTS CRITICALITY ANALYSIS) DALAM IDENTIFIKASI TITIK KRITIS DI INDUSTRI KEMASAN Arif Rahman; Farah Fahma
Jurnal Teknologi Industri Pertanian Vol. 31 No. 1 (2021): Jurnal Teknologi Industri Pertanian
Publisher : Department of Agroindustrial Technology, Bogor Agricultural University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24961/j.tek.ind.pert.2021.31.1.110

Abstract

XYZ is a company engaged in packaging, especially for pharmaceuticals. The company has recorded an overall defective product known as end to end waste. During 2019 the average end to end waste was 12.37%, while the target of company management was 9%. The objective of this research is to minimize defective products and to find out what types of defects occur in the production process. The method used in this research is FMECA (Failure Modes, Effects and Critically Analysis), which is the development of the FMEA (Failure Mode and Effect Analysis) method which functions to make analyzes from production tools or processes, types of defects to the effects that arise as a result. of the defect, but also to determine the critical point. The results of the analysis that has been carried out using the FMEA method with RPN (Risk Priority Number) calculations, then analysis with the Pareto diagram and criticality matrix, the researcher gets 10 priority failure modes, namely the machine often stops due to a lot of paper dust, too high piles, unstable colors because there is a change in ink, the non-stop feeder is damaged, the front lay and side lay are unstable from the printing process, the side lay sensor does not work, the actual chiller temperature with the display is not the same, the paper is untidy from the printing process, the paper is untidy from the calendering process, and the chiller is leaking. The researcher also gave recommendations, namely making a Standard Operation Procedure (SOP) for handling dusty paper, submitting complaints to suppliers regarding paper quality, providing a printing unit, and training for dusty paper handling. Keywords: criticality matrix, FMECA, risk priory number, pareto diagram
TINJAUAN METODE POTENSIAL SINTESIS BIONANOKOMPOSIT ANTISTATIS YANG DIPERKUAT DENGAN MONO-DIASILGLISEROL DAN NANOKRISTAL SELULOSA Muhammad Syukur Sarfat; Dwi Setyaningsih; Farah Fahma; Nastiti Siswi Indrasti; Sudirman Sudirman
Jurnal Teknologi Industri Pertanian Vol. 31 No. 3 (2021): Jurnal Teknologi Industri Pertanian
Publisher : Department of Agroindustrial Technology, Bogor Agricultural University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24961/j.tek.ind.pert.2021.31.3.316

Abstract

In the last 10 years, the research about the technology of bionanocomposite synthesis has increased rapidly,starting from the simple technology to advanced technology of synthesis. From the several technologies ofsynthesis of bionanocomposite that have been developed, each has its own advantages and disadvantages.Therefore, the selection of the right technology of synthesis of bionanocomposite is one of the indicators of successin its synthesis. This review identified the latest developments in technology of synthesis of bionanocomposite andfocuses on methods of synthesis of bionanocomposite was most widely used and a technology that has advantagesover other technologies. It is hoped that this review can provide information about methods of synthesis ofbionanocomposite in general and specifically can provide information about methods of synthesis ofbionanocomposite reinforced with mono-diacylglycerol (M-DAG) and cellulose nanocrystal (CNC). Based on theidentification from several result of research, potential method to synthesis of bionanocomposite are combinationof two methods, namely twin-screw extrusion method and injection molding method. Those technologies can be analternative potential methods of synthesis of antistatic bionanocomposite reinforced with M-DAG and CNC.Keywords: cellulose nanocrystal, injection molding, mono-diacylglycerol, technology of synthesis of antistaticbionanocomposite, twin-screw extrusion
CELLULOSIC PADS AS MATRIX SACHET ANTIMICROBIAL: A REVIEW Syifa Robbani; Farah Fahma; Sugiarto Sugiarto
AGROINTEK Vol 15, No 2 (2021)
Publisher : Agroindustrial Technology, University of Trunojoyo Madura

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21107/agrointek.v15i2.9366

Abstract

The advancement of active packaging technology has contributed to the need for customer assurance of the quality and protection of fresh foods and agricultural products. An example of active packaging to maintain food quality and improve product protection is the use of antimicrobial pads. Antimicrobial pads are a type of active packaging that releases active agents into the headspace food packaging in order to prevent, inhibit or destroy the growth of microorganisms.. Antimicrobial pads are very easy to apply to food products by placing them on the bottom of the product or inserting them into the packaging material. This literature study discusses the characterization of cellulose as a major component in the manufacture of pads, techniques for the incorporation of antimicrobial compounds into pads, and suitable applications for the inhibition of microorganisms in food products. Apart from that, this literature study also discusses the advantages and disadvantages of antimicrobial pads as active packs.
TABLET ANTIMIKROBA UNTUK APLIKASI KEMASAN AKTIF Hurun Iin; Sugiarto Sugiarto; Farah Fahma
AGROINTEK Vol 15, No 4 (2021)
Publisher : Agroindustrial Technology, University of Trunojoyo Madura

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21107/agrointek.v15i4.9311

Abstract

Antimicrobial active packaging is designed to extend the shelf life of packaged products by adding antimicrobial agents to the packaging system. Trend of green consumerism has led to an increasing demand for the use of natural antimicrobial agents for food packaging applications. The natural antimicrobial agents that are the focus of current research are essential oils, however, the application of essential oils directly to packaging materials can affect mechanical characteristics such as a decrease in the tensile strength of the packaging materials. One of the innovations to solve this weakness is the application of an antimicrobial agent with a carrier material in the form of sachets, pads and tablets. The principle of the antimicrobial active packaging is the adsorption of active compounds on the carrier material and allows the slow release of active antimicrobial compounds in the packaging system. Furthermore, challenges in the food sector related to packaging waste have prompted research on biodegradable materials, such as the use of starch and cellulose as carrier materials. This paper examines the development of antimicrobial packaging with essential oil active agents using several types of carrier materials, how to produce these packages with several types of materials, and the advantages and disadvantages of selecting the materials used.
Utilization of Cellulose from Pineapple Leaf Fibers as Nanofiller in Polyvinyl Alcohol-Based Film Kendri Wahyuningsih; Evi Savitri Iriani; Farah Fahma
Indonesian Journal of Chemistry Vol 16, No 2 (2016)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (383.638 KB) | DOI: 10.22146/ijc.21162

Abstract

 Cellulose from pineapple leaf fibers as one of the natural polymer which has biodegradable property in a nanometer’s scale, can be formed as a filler in composite of Poly(vinyl) Alcohol/PVA is expected to increase the physical, thermal, and barrier properties of composite films similar to conventional plastic. The aim of this study was to examine the effect of fibrillation of cellulose fibers from pineapple leaf fibers using a combined technique of chemical-mechanical treatments, to investigate the reinforcing effect of concentration of nanocellulose fibrils in the polyvinyl alcohol (PVA) matrix on physical properties, thermal properties, water vapor transmission rate, light transmittance and morphological with and without addition of glycerol. Nanocellulose was made from cellulose of pineapple leaf fiber using wet milling (Ultra Fine Grinder). The composite film production was carried out by using casting solution method by mixing PVA solution with nanocellulose (10-50%) and glycerol (0-1%). The characterization of film covered physical properties (thickness, moisture content and density), thermal properties, permeability (WVTR), light transmittance, morphology, and crystallinity. Nanocellulose from pineapple leaf fibers was produced by Ultra Fine Grinder shows that the size reduction process was accurate. Nanocellulose addition on PVA composite film was affected to increasing the physical, thermal, and barrier properties. Meanwhile, decreasing the percentage of composite film transmittance, thus the transparency decrease (opaque). Water vapor transmission rate (WVTR) the film was increased with increasing glycerol concentration, but the physical and thermal properties was decreased.
On the Mechanical and Thermal Properties of Poly(Vinyl Alcohol) – Alginate Composite Yarn Reinforced with Nanocellulose from Oil Palm Empty Fruit Bunches Ainul Maghfirah; Farah Fahma; Nurmalisa Lisdayana; Muchammad Yunus; Ahmad Kusumaatmaja; Grandprix Thomryes Marth Kadja
Indonesian Journal of Chemistry Vol 22, No 1 (2022)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijc.67881

Abstract

PVA-alginate hydrogel is a promising material for use in biomedical applications due to its desirable characteristics: biocompatible, durable, non-toxic, and low cost. However, the low gel strength of this composite limits its use in biomedical applications. This study aims to develop enhanced mechanical and thermal properties of poly(vinyl alcohol) PVA-alginate composite yarn by adding nanocellulose isolated from the sustainable oil palm empty fruit bunches (OPEFBs). The PVA-alginate composite yarns reinforced with nanocellulose were prepared with various nanocellulose contents (1 wt.%, 2 wt.%, and 5 wt.%). The composite's tensile strength exhibited an increasing trend with the addition of nanocellulose, while the elongation at break showed the opposite trend. Moreover, it was demonstrated that the composite's thermal degradation shifts to higher temperatures with the addition of nanocellulose. The observed activation energies for the thermal degradation calculated using the Coats-Redfern method exhibited a significant increment for the composites reinforced with nanocellulose. These results show that the addition of nanocellulose into the PVA-alginate matrix enhances the chemical and thermal properties of the resulting hydrogel. All these improvements have resulted from more abundant and robust hydrogen bonds generated by the nanocellulose presence.
Teknik Ekstraksi dan Nanoenkapsulasi Komponen Bioaktif Buah Malaka: Tinjauan Literatur Nida El Husna; Erliza Noor; Farah Fahma; Titi Candra Sunarti
AGROINTEK Vol 16, No 2 (2022)
Publisher : Agroindustrial Technology, University of Trunojoyo Madura

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21107/agrointek.v16i2.12433

Abstract

The bioactive components of malacca (Emblica officinalis), which consist of phenolic, alkaloids, phytosterols, organic acids, and vitamins, are valuable for human health. The yield and quality of the bioactive components in the extract highly depend on the extraction technique, so it is essential to know the development of research on extraction techniques of the bioactive components of malacca fruit. In addition, the bioactive components in the extract have limitations in their application due to their stability, solubility, absorption, and bioavailability properties. Currently, nanoencapsulation technology has been applied to extracts of bioactive components to improve their properties. This review aims to provide comprehensive information about extraction techniques to obtain bioactive components of malacca fruit and presents the technique and purpose of the nanoencapsulation of malacca fruit extract. In addition to conventional techniques, several modern extraction techniques such as microwave-assisted extraction (MAE), ultrasound (UAE), pulsed electric field (PEF), and supercritical fluid (SFE) have been used to extract bioactive components of malacca fruit. Modern extraction techniques can produce extracts of bioactive components with higher yields than conventional techniques. The application of nanoencapsulation technology to malacca fruit extract consists of nanoliposomes and nanoparticles can increase permeability, antioxidant activity, antidiabetic and anti-inflammatory properties of malacca fruit extract.