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All Journal Indonesian Journal of Applied Sciences Jurnal Penelitian Sains Jurnal Kesehatan Saelmakers PERDANA (JKSP)
Masayu Azizah
Program Studi SI Farmasi, Sekolah Tinggi Ilmu Farmasi Bhakti Pertiwi Palembang
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Environmental Science Health Professions Immunology & microbiology Mathematics Medicine & Pharmacology Nursing Physics

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Uji Aktivitas Antibakteri Kombinasi Ekstrak Etanol Daun Seledri (Apium graviolens L.) Dan Madu Hutan Terhadap Beberapa Bakteri Penyebab Penyakit Kulit Masayu Azizah; Lara Septy Lingga; Yopi Rikmasari
Jurnal Penelitian Sains Vol 22, No 1 (2020)
Publisher : Faculty of Mathtmatics and Natural Sciences

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (797.144 KB) | DOI: 10.56064/jps.v22i1.547

Abstract

Telah dilakukan uji aktivitas antibakteri dari ekstrak etanol daun seledri (Apium graviolens L.) dan madu hutan terhadap bakteri penyebab penyakit kulit yaitu Staphylococcus aureus ATCC 25923, Streptococcus pyogenes ATCC 19615, Propionibacterium acnes ATCC 11827, Pseudomonas aeruginosa ATCC 27853, Sreptococcus β hemoliticus ATCC 19615. Ekstraksi dilakukan dengan cara maserasi menggunakan pelarut etanol destilat. pengujian aktivitas antibakteri dilakukan dengan menggunakan metode difusi agar dengan konsentrasi zat uji yaitu 70%:30%, 60%:40% dan 50%:50% dengan menggunakan etanol destilat sebagai kontrol negatif dan kloramfenikol sebagai kontrol positif. Hasil penelitian menunjukkan daya hambat ekstrak pada konsentrasi 70%:30% pada masing-masing bakteri uji yaitu Staphylococcus aureus ATCC 25923  sebesar 17 mm, Streptococcus pyogenes ATCC 19615 sebesar 18,6 mm, Propionibacterium acnes ATCC 11827 sebesar 17,9 mm, Pseudomonas aeruginosa ATCC 27853 sebesar 18,6 mm, Sreptococcus β hemoliticus ATCC 19615 sebesar 16,15 mm. hasil penelitian menunjukkan bahwa ekstrak etanol daun seledri dan madu hutan memiliki aktivitas antibakteri terhadap bakteri infeksi kulit dalam kategori kuat
EFEK IMUNOMODULATOR EKSTRAK ETANOL KULIT BUAH NANAS (Ananas comosus L.Merr) TERHADAP MENCIT PUTIH JANTAN DENGAN METODE BERSIHAN KARBON (Carbon Clearance) Masayu Azizah; Wiwik Wiraningsih; Ema Ratna Sari
Indonesian Journal of Applied Sciences Vol 7, No 2 (2017)
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (519.132 KB) | DOI: 10.24198/ijas.v7i2.13707

Abstract

AbstractThis research was aimed to study the immunomodulatory effect of ethanol extract of pineapple (Ananas comosus L. Merr) peel on white male mice with carbon clearance method. Animals  were divided into 5 groups: Group 1 was given tween 80 1 % v/v;Ggroup 2 was given meniran extracts; Group 3, 4 and 5 were given  ethanol extracts of pineapple peel with a dose of 125 mg/kg BW, 250 mg/kg BW, and 500 mg/kg BW,respectively, for 6 days orally. On the 7th day the animals were injected with carbon suspension 0.2 ml/20g BW at the tail vein. Blood was taken at 5th and 15th minutes using capillary pipe from the animal’s orbital retro vein, then it was diluted with 4 ml of 0.1% b/v sodium carbonate and measured its absorbance at 675 nm using visible spectrophotometer. The ethanol extract of pineapple peel showed immunomodulatory effect where the best dose was 250 mg/kg BW.  Keywords                : biological response modifiers, immunomodulatory, pineapple peel
PENGARUH AKTIVITAS FISIK ANAEROBIK TIAP HARI TERHADAP KADAR HEAT SHOCK PROTEIN (HSP)70 OTOT JANTUNG TIKUS WISTAR Masayu Azizah; Rostika Flora; Theodoru Theodoru
Indonesian Journal of Applied Sciences Vol 5, No 1 (2015)
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (4009.586 KB) | DOI: 10.24198/ijas.v5i1.16650

Abstract

AbstrakHeat Shock Protein (HSP) merupakan suatu protein yang dihasilkan karena adanya Heat Shock Response (HSR). HSR diperlukan sebagai tanggapan sel terhadap berbagai macam gangguan, baik yang bersifat fisiologis maupun yang berasal dari lingkungan. Peningkatan kadar HSP70 otot jantung ini dikarenakan adanya aktivitas fisik anaerobik. Aktivitas fisik ini mengakibatkan tubuh mengalami peningkatan suhu tubuh, stres panas dan latihan.Tujuan penelitian ini adalah untuk menganalisa pengaruh aktivitas fisik anaerobik yang dilakukan setiap hari terhadap kadar Heat Shock Protein (HSP)70 otot jantung tikus wistar. Berdasarkan hasil penelitian, kelompok anaerobik menunjukkan peningkatan kadar HSP otot jantung dibandingkan kelompok pembanding.Kata kunci : aktivitas fisik anaerobik tiap hari, HSP70, treadmill, tikus rattus novergicus wistar.AbstractHeat Shock Protein (HSP) is a protein that is produced because of the Heat Shock Response (HSR). HSR is required as a response of cells to a variety of disorders, both physiological as well as from the environment. Increased levels of HSP70 heart muscle is due to anaerobic physical activity. Physical activity causes the body to increase body temperature, heat stress and latihan.Tujuan this study is to analyze the influence of anaerobic physical activity performed every day on levels of Heat Shock Protein (HSP) 70 wistar rat cardiac muscle. Based on the results of the study, the group showed increased levels of HSP anaerobic heart muscle than the comparison group.Keywords : anaerobic physical activity every day , HSP70 , body temperature, rattus novergicus wistar rat.
UJI AKTIVITAS ANTI BAKTERI EKSTRAK ETANOL DAUN PANDAN WANGI (Pandanus amaryllifolius Roxb) TERHADAP BAKTERI PENYEBAB DIARE Jacky; Dea Anggi Putri; Masayu Azizah
Jurnal Kesehatan Saelmakers PERDANA (JKSP) Vol. 2 No. 1 (2019): Jurnal Kesehatan Saelmakers PERDANA
Publisher : Fakultas Ilmu Kesehatan Universitas Katolik Musi Charitas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32524/jksp.v2i1.200

Abstract

Diarrhea is still a major problem in children's health, especially in developing countries like Indonesia.. One of alternative medicine that have potential as antibacterial is pandan wangi leaves. This study aims to knowing effect of pandan wangi leaves ethanol extract as an antibacterial against. The design of this study was experimental. The antibacterial activity was determined by agar diffusion method with concentration extract respectively 40%, 50%, 60%, cotrimoxazole as positive control. The result of the research shows that etanol extract of pandan wangi leaves has the antibacterial effect to Bacillus cereus ATCC 11778 with inhibition capability 7,90 mm, 8,90 mm, 10,13 mm, 12,3 mm. Enterococcus faecalis ATCC 29212 8,10 mm, 9,26 mm, 10,20 mm, 12,2 mm. Shigella dysentri ATCC 11835 8,56 mm, 8,80 mm, 11,90 mm, 13,3 mm. Vibrio cholerae ATCC 14033 8,16 mm, 9,10 mm, 11,20 mm, 12,2 mm. Escherichia coli ATCC 25922 8,16 mm, 9,63 mm, 11,85 mm, 13,0 mm. Extract concentration that giving the most optimal inhibition capability to bacteria that causes diarrhea is concentration 60%.
Uji Aktivitas Anti Jamur Ekstrak Etanol Biji Alpukat (Persea americana Mill) Terhadap Jamur Kulit Tricophyton rubrum ATCC 28188, Epidermophyton floccosum ATCC 50266 dan Micospprum canis ATCC 32699) Masayu Azizah; Panji Taruna Anugrah Akbar; Mauizatul Hasanah
Jurnal Kesehatan Saelmakers PERDANA (JKSP) Vol. 4 No. 2 (2021): Jurnal Kesehatan Saelmakers PERDANA
Publisher : Fakultas Ilmu Kesehatan Universitas Katolik Musi Charitas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32524/jksp.v4i2.264

Abstract

Antifungal activity test of avocado seed extract (Persea americana Mill) against fungi that cause dermatophytosis skin disease, namely Trichophyton rubrum ATCC 28188, Epidermophyton floccosum ATCC 50266 and Microsporum canis ATCC 32699. Phytochemical test results of avocado seeds contain phenolic compounds, saponins, alkaloids, flavonoids. The antifungal activity test of ethanol extract of avocado seeds used the agar diffusion method, with a concentration of 26,25%, 48,75%, 75%, and the positive control used was ketoconazole and ethanol distillate negative control. The results showed that the diameter of the zone of inhibition against the fungus Trichophyton rubrum ATCC 28188 with an inhibition zone diameter of 7.5 mm, 9.8 mm, 12 mm, against the fungus Epidermophyton floccosum ATCC 50266, the inhibition zone diameter was 7.4 mm, 9, 7 mm, 11.7 mm and against fungi Microsporum canis ATCC 32699 the inhibition zone was 8.4 mm, 10.1 mm, 13.4 mm. It can be concluded that the ethanol extract of avocado seeds has antifungal activity against. Trichophyton rubrum ATCC 28188, Epidermophyton floccosum ATCC 50266 and Microsporum canis ATCC 32699 The greatest antifungal activity was against Microsporum canis at a concentration of 75% with a diameter of 13.4 mm in the strong category
Co-Authors Dea Anggi Putri Jacky Lara Septy Lingga Mauizatul Hasanah Panji Taruna Anugrah Akbar Rostika Flora Theodoru Theodoru Wiwik Wiraningsih Yopi Rikmasari, Yopi