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Rini Isromarina
Sekolah Tinggi Ilmu Farmasi Bhakti Pertiwi Palembang
Agriculture, Biological Sciences & Forestry Chemistry Health Professions Immunology & microbiology Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Physics

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Journal : Jurnal Penelitian Sains

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Aktivitas Antijamur Fraksi Ekstrak Etanol Daun Pare (Momordica charantia L.) terhadap Microsporum canis ATCC 32699 Reza Agung Sriwijaya; Rini Isromarina; Meyla Rosada
Jurnal Penelitian Sains Vol 20, No 2 (2018)
Publisher : Faculty of Mathtmatics and Natural Sciences

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (352.584 KB) | DOI: 10.56064/jps.v20i2.506

Abstract

Pare is one of the plants used as an herbal medicine, one of which is for infectious diseases. This study aimed to evaluate the antifungal activity ethanol extract fraction leaves of Pare. The extraction was carried out using maceration method and then fractionated using n-hexane, ethyl acetate and water solvents. The antifungal activity was determined using the agar diffusion method. The test fungus was using Microsporum canis at a serial concentration of 1,5%, 1% and 0,5%. The results of antifungal activity test of n-hexane fraction, ethyl acetate fraction and water fraction of Pare leaf ethanol extract showed the existence of inhibitory zone diameter. In the n-hexane fraction, ethyl acetate and water frac-tion the diameter of the largest inhibitory zone was 11,7 mm, 11,6 mm and 10,1 mm. Inhibitory zone showed that the fraction of ethanol extract of Pare leaves has antifungal activity.
Aktivitas Antibakteri Ekstrak N-Heksan, Kloroform Dan Etanol Daun Nangka (Artocarpus Heterophyllus Lam.) Terhadap Propionibacterium acnes ATCC 11827 Rini Isromarina; Yunita Listiani Imanda; Mira Susanti
Jurnal Penelitian Sains Vol 24, No 2 (2022)
Publisher : Faculty of Mathtmatics and Natural Sciences

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (258.816 KB) | DOI: 10.56064/jps.v24i2.633

Abstract

Nangka merupakan salah satu tanaman yang digunakan sebagai obat herbal, salah satunya untuk penyakit infeksi. Tujuan penelitian untuk mengetahui aktivitas antibakteri ekstrak n-heksan, kloroform dan etanol daun nangka (Artocarpus heterophyllus Lam.) Ekstraksi dilakukan dengan cara beringkat dengan metode sokhletasi. Uji aktivitas antibakteri dilakukan dengan menggunakan metode difusi agar. Bakteri uji yang digunakan adalah Propionibacterium acnes ATCC 11827 dengan konsentrasi ekstrak 10.000 µg/mL, 5.000 µg/mL. 2.500 µg/mL dan 1.250 µg/mL. Uji aktivitas antibakteri ekstrak n-heksan, kloroform dan etanol daun nangka menunjukkan ada diameter hambat. Pada ekstrak n-heksan, kloroform dan etanol daun nangka diperoleh diameter hambat paling besar berturut-turut 12,26 mm, 12,36 dan 12,26 mm. Uji fitokimia dengan KLT menunjukkan bahwa ekstrak n-heksan mengandung terpenoid dan steroid, ekstrak kloroform mengandung fenol, dan ekstrak etanol mengandung flavonoid. Hal ini menunjukkan bahwa senyawa aktif pada ekstrak mampu menghambat pertumbuhan Propionobacterium acnes ATCC 11827.
Co-Authors Deva Ulan Sari Doddy Rusli Elvera Rosa Meyla Rosada Mira Susanti Nadya Rizki Putri Intan Reza Agung Sriwijaya