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All Journal Jurnal Fitofarmaka Indonesia As-syifaa Jurnal Farmasi Majalah Farmaseutik Jurnal Mandala Pengabdian Masyarakat

Rahmawati Rahmawati

Fakultas Farmasi Universitas Muslim Indonesia

Author-ID : 2485516

Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology Public Health Social Sciences

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Articles

In Vitro Anti-Inflammatory Assay of Bitter Melon (Momordica charantia L.) Ethanol Extract Rahmawati Rahmawati; Harti Widiastuti; Eka Sulistya
Jurnal Fitofarmaka Indonesia Vol 7, No 3 (2020): JURNAL FITOFARMAKA INDONESIA (English Edition)
Publisher : Faculty of Pharmacy, Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/jffi.v7i3.655

Bitter melon contains flavonoids that have anti-inflammatory function. Inflammation can be caused by protein denaturation. This research tested the anti-inflammatory potential of ethanol extract of leaves and bitter melon (Momordica charantia L.) using a UV-Vis spectrophotometer and protein denaturation inhibition method. There were three experimental groups formed in this research including negative control group, positive control group, and test solutions. Diclofenac sodium was used in the positive control group at concentration series of 1, 2, 4, 8, and 16 ppm, obtaining a regression equation Y = 3.546X + 2.163 and r = 0.9990. Whilst, for bitter melon ethanol extract at a series of concentrations of 10, 20, 40, 80 and 160 ppm obtained a regression equation Y = 0.243X + 11.74 and r = 0.9995. The potential of diclofenac sodium as an anti-inflammatory agent was shown by IC50 of 13.490 µg / mL, while the ethanol extract of bitter melon fruit has an IC50 of 157.448 µg / mL. This result indicated that bitter melon ethanol extract had the potential as moderate anti-inflammatory agent.

ANALISIS AKTIVITAS PERLINDUNGAN SINAR UV SARI BUAH SIRSAK (Annona muricata L.) BERDASARKAN NILAI SUN PROTECTION FACTOR (SPF) SECARA SPEKTROFOTOMETRI UV-VIS Rahmawati Rahmawati; A. Muflihunna; Meigita Amalia
Jurnal Fitofarmaka Indonesia Vol 5, No 2 (2018): JURNAL FITOFARMAKA INDONESIA
Publisher : Faculty of Pharmacy, Universitas Muslim Indonesia

Sunlight contains UV rays that adversely affect the skin. These adverse effects can be minimized by the use of UV protective materials, both natural and synthetic. Soursop fruit (Annona muricata L.) has a high content of polyphenol compounds, some vitamins such as vitamin C, B1 and B2. This study aims to determine the activity of UV light protection on soursop juice (Annona muricata L.) by using Sun Protection Factor (SPF) calculation. The measurement of SPF values using the UV-Vis spectrophotometric method in the wavelength range from 290-320 nm. The results showed that soursop juice (Annona muricata L.) had UV light protection activity at 1% concentration of 5,188, 3% concentration of 12.242 and 5% concentration of 17,247. The category of SPF values in a row that is medium, maximum and ultra

ANALISIS KANDUNGAN VITAMIN C DAN β- KAROTEN DALAM DAUN KELOR (Moringa oleifra Lam.) DENGAN METODE SPEKTROFOTOMETRI UV–VIS Masdiana Tahir; Nurul Hikmah; Rahmawati Rahmawati
Jurnal Fitofarmaka Indonesia Vol 3, No 1 (2016): JURNAL FITOFARMAKA INDONESIA
Publisher : Faculty of Pharmacy, Universitas Muslim Indonesia

This research aimed to analyze the levels of vitamin C and β-carotene in Moringa leaves extract (Moringa oleifera Lam.) using UV-Vis spectrophotometry. Vitamin C on Moringa leaves are extracted with ethanol 96%. The extracts obtained was qualitatively analyzed of levels of vitamin C using specific reagents an iodine 1% and ammonium molybdate 5%. Than quantitatively using UV-Vis spectrophotometry at wavelength of 570 nm, obtained an verage grade of 7,96 mg/g. For β-carotene, Moringa leaves were extracted with acetone. The extract obtained was extracted again with ether, then saponified with KHO solvent 15% w/v in methanol, allowed to stand overnight. The extract obtained was extracted again with ether, then freed from wet with distilled water. Extracts were analyzed qualitatively using thin layer chromatography and quantitatively using UV-Vis spectrophotometry at wavelength of 450 nm and obtained an average grade of 3,31 mg/g.

ANALISIS AKTIVITAS ANTIOKSIDAN PRODUK SIRUP BUAH MENGKUDU (Morinda citrifolia L.) DENGAN METODE DPPH Rahmawati Rahmawati; A. Muflihunna; Laode Muhammad Sarif
Jurnal Fitofarmaka Indonesia Vol 2, No 2 (2015): JURNAL FITOFARMAKA INDONESIA
Publisher : Faculty of Pharmacy, Universitas Muslim Indonesia

This research is about antioxidant activity analysis of Noni products syrup (Morinda citrifolia L.) using DPPH (1,1-diphenyl-2-picrylhydrazil) method. The research aimed to analysis of antioxidant activity of two different brands of Noni products syrup using spectrophotometer UV-Vis. This analysis using quarcetin as standard to determine antioxidant activity and DPPH reagen as radical sources. Quarcetin and Noni products syrup are made five series concentrations in metanol. One ml of each concentration added 4 ml DPPH 50 µM and then added metanol up to 10 ml in flask. Then incubated for 30 minutes at room temperature and protected from light. Measurement of absorbance using spectrophotometer UV-Vis at 514 nm. The IC50 values were 25.7 µg/mL for brand A, and 9.839 µg/mL for brand B.

ANALISIS KADAR FLAVONOID DAN FENOLIK TOTAL FRAKSI ETIL ASETAT DAUN KETEPENG CINA (Senna alata (L.) Roxb) DENGAN METODE SPEKTROFOTOMETRI UV-VISIBLE Rahmawati Rahmawati; A. Muflihunna; A. Trihadi Kusuma
As-Syifaa Jurnal Farmasi Vol 7, No 1 (2015): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Analysis of flavonoid and phenolic content of ethyl acetate fraction have done in chinese ketepeng leaves (Senna alata (L.) Roxb) using UV-Visible spectrophotometric method. This research aimed to analyzed of flavonoids and phenolic content of ethyl acetate fraction of chinese ketepeng leaves. Chinese ketepeng leaves were extracted using ethanol 96%, and then were partitioned using a liquid-liquid partition method of ethyl acetate to obtain ethyl acetate fraction. Flavonoid and phenolic content determined using UV-VIS spectrophotometric at 415 nm wavelength for flavonoid and 730 nm for phenolic. This research results showed that the flavonoid content of ethyl acetate fraction of chinese ketepeng leaves is 2,665 mgRE/g and phenolic content of ethyl acetate fraction of chinese ketepeng leaves is 3,729 mgRE/g.

ANALISIS KADAR ARSEN (As) DAN TIMBAL (Pb) PADA MINYAK GORENG PEMAKAIAN BERULANG DENGAN METODE SPEKTROFOTOMETRI SERAPAN ATOM Aminah Aminah; Rahmawati Rahmawati; Tadjuddin Naid; Salma Salma
As-Syifaa Jurnal Farmasi Vol 9, No 1 (2017): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

This study aims to analyze the levels of arsenic (As) and lead (Pb) in frying oil usage over and over. This research was conducted at the Center for Health Laboratory Makassar. Samples obtained from merchants fried foods. To ensure the metal content of the samples prior didestruksi with HNO3P and heated for 16 hours to liberate arsenic and lead from the oil matrix, then measured using atomic absorption spectrophotometer (AAS) at a wavelength of 193.7 nm (Arsenic) and 283 nm (lead ). From the results obtained penilitian arsenic (As) in the three vendors that is <0.1 ppm (max 0.1 ISO ppm) and lead levels that merchants 1 (0.1503 mg / kg and 0.1940 mg / kg), traders 2 (0.3452 mg / kg and 0.4005 mg / kg), the merchant 3 (0.1111 mg / kg and 0.1788 mg / kg) respectively for the samples before and after frying (SNI max 0.1 mg / kg).

Potential of Anticoagulan Garlic Estract (Allium sativum) Using Lee-White Method and Blood Destruction Rahmawati Rahmawati; Muammar Fawwas; Rais Razak; Utami Islamiati
Majalah Farmaseutik Vol 14, No 1 (2018)
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Garlic (Allium sativum L.) contains essential oils, allicin compounds, alliin and other organosulfur compounds such as ajoene which play a role in anticoagulants. This study aimed to examine the anticoagulant activity of garlic extract using the Lee-White method and blood smear. Anticoagulant activity testing was carried out by looking at the time it took for the blood to freeze after adding garlic juice, 96% ethanol (negative control) and EDTA (positive control) and looking at the red blood cell profile under a microscope (blood smear). From the test results showed that garlic extract had anticoagulant activity in which the Lee-White method, blood control freezing for three consecutive probes occurred at 4 minutes, 3 minutes 30 seconds and 3 minutes 30 seconds; addition of 96% ethanol occurred at 4 minutes 30 seconds, 2 minutes 30 seconds and 2 minutes 30 seconds and the addition of EDTA and garlic extract did not experience blood clots. Then in the blood smear method, the red blood cells added with garlic juice look round and not in groups.

AKTIVITAS SENYAWA FLAVANOID EKSTRAK ETANOL BUNGA KERSEN (Muntingia calabura L) SEBAGAI TABIR SURYA Masdiana Tahir; Rahmawati Rahmawati; St Maryam; Putri Nurfauziah; Naura Nazhifah
As-Syifaa Jurnal Farmasi Vol 14, No 2 (2022): AS-SYIFAA JURNAL FARMASI
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56711/jifa.v14i2.839

Chronic exposure to ultraviolet rays from the sun might result in oxidative stress, changes in the structure and composition of the skin. Sunscreen preparations are recommended to be used to prevent or minimize the harmful effects of UV rays on the skin. Sunscreen can be obtained from natural ingredients, one of which is the flower of cherry (Muntingia calabura L.). This study aims to identify the content of flavonoids and test the sunscreen activity of the ethanol extract of cherry flower (Muntingia calabura L.) in vitro using the UV-Vis spectrophotometric method based on the SPF value. Flavonoids are claimed to be capable to blocking ultraviolet (UV) light-induced radicals that have a protective effect against UV radiation, where the SPF value is a universal measure that describes the potency of a UV defense material. The findings of this study showed that the ethanol extract of cherry flowers positively contained flavonoid compounds including the flavonol, flavanone, and anthocyanidin groups. The results of the sunscreen activity test showed that the ethanol extract of cherry flowers had sunscreen activity at a concentration of 0.01% with an SPF value of 10.9 (moderate SPF), 0.05% with an SPF value of 41.6 (high SPF), 0,15% with an SPF value of 45.5 (high SPF). and 0.25% with an SPF value of 48.7 (high SPF). The higher the extract concentration, the higher the SPF value indicating the greater the activity as sunscreen.

KAJIAN ETNOFARMASI DENGAN PENGGUNAAN TANAMAN OBAT TRADISIONAL DI KECAMATAN TANRALILI, KABUPATEN MAROS, PROVINSI SULAWESI SELATAN Rahmawati Rahmawati; Risda Waris; St Hadijah S
As-Syifaa Jurnal Farmasi Vol 14, No 2 (2022): AS-SYIFAA JURNAL FARMASI
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56711/jifa.v14i2.899

The study of ethnopharmaceuticals is a scientific approach that can assist in exploring the knowledge of the local tribe towards traditional plants that are efficacious as medicine and still rely on or use plants as medicine. This study aims to determine the use of medicinal plants which include the parts of the plants used, processing methods and usage methods. The method used in this research is purposive sampling method. The results of the study obtained as many as 42 species spread into 28 and have 3 plants that have frequency values, Use Value (UV) and percent of plants including soursop, kaposanda and papaya plants and the lowest values are bandotan, chicken dung, cinnamon, gedi, tapak liman plants used by the people of Tanralili sub-district, Maros district as traditional medicine. The conclusion is that the level of knowledge related to the use of traditional medicinal plants tends to still use and utilize and as an alternative treatment.This plant has the highest parameter of frequency 28, Use Value (UV) is 0.28 and plant percent is 11.97% on soursop plants and has the lowest value with a frequency value of 1, Use value (UV) is 0.01 and percent of plants namely 0.43% on bandotan, chicken dung, cinnamon, gedi, tapak liman and sweet potato plants

Making of “JE-LI” Liquid Hand Soap to Prevent of Covid-19 Spreading Rahmawati Rahmawati; A. Muflihunna; Sitti Maryam
Jurnal Mandala Pengabdian Masyarakat Vol. 3 No. 2 (2022): Jurnal Mandala pengabdian Masyarakat
Publisher : Progran Studi Farmasi STIKES Mandala Waluya

Pemerintah mencanangkan protokol kesehatan di saat terjadinya pandemi virus Corona-19, salah satunya ialah rajin mencuci tangan pakai sabun demi membantu mencegah penyebaran virus tersebut. Kegiatan pengabdian ini bertujuan untuk memberikan pelatihan pembuatan sabun cair cuci tangan “Je-Li” kepada para siswa dan guru SD Negeri 29 Banyuanyara, kecamatan Sanrobone, kabupaten Takalar. Sabun ini diperkaya dengan sari jeruk nipis dan lidah buaya yang efektif sebagai anti bakteri dan dapat melembutkan kulit tangan (moisturizer). Pengabdian ini diawali dengan pemberian materi, dilanjutkan dengan pelatihan cara membuat sabun dan terakhir dilakukan evaluasi dengan melakukan tanya jawab untuk mengetahui pemahaman materi yang telah diberikan. Mitra terdiri dari 21 orang siswa-siswi kelas 6 dan 8 orang guru. Hasil yang diperoleh adalah mitra memiliki pemahaman dan keterampilan dalam membuat sabun cair cuci tangan “Je-Li” yang dapat digunakan pada pelaksaan sekolah offline. Diharapkan para siswa dan guru di sekolah menerapkan protokol kesehatan, yaitu rajin mencuci tangan dengan sabun demi menjaga kebersihan tangan dan mencegah penularan Covid-19.

Co-Authors A. Muflihunna A. Muflihunna A. Trihadi Kusuma Aminah Aminah Anak Agung Istri Sri Wiadnyani Eka Sulistya Harti Widiastuti Laode Muhammad Sarif Masdiana Tahir Masdiana Tahir Meigita Amalia Muammar Fawwas Naura Nazhifah Putri Nurfauziah Rais Razak Risda Waris Salma Salma Sitti Maryam St Hadijah S St Maryam Tadjuddin Naid Utami Islamiati

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