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Clinical Characteristic and Outcome of Acute Lower Respiratory Tract Infection in Children with Congenital Heart Disease Krystle Gabriela; Rahmat Budi Kuswiyanto; Fenny Dwiyatnaningrum
Althea Medical Journal Vol 2, No 3 (2015)
Publisher : Faculty of Medicine Universitas Padjadjaran

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Background: Acute Lower Respiratory Tract Infection (ALRTI) is the leading cause of deaths in children under 5 years of age worldwide, and has high morbidity and mortality in children with Congenital Heart Disease (CHD). The objective of this study was to obtain the incidence, clinical characteristic, and outcome of ALRTI children with CHD.Methods: A retrospective hospital-based study was conducted from January 2007–December 2011 to medical record of child patients with ALRTI and CHD in the Department of Child Health of Dr. Hasan Sadikin General Hospital, Bandung. The diagnosis of CHD was determined by echocardiography. The collected data was analyzed and presented in percentage shown in tables.Results : From 3,897 children who had ALRTI, there were 149 children with CHD (3.8%), with 11.4% of whom founded with recurrent episodes. This happened often in girls than boys with quite similar ratio of 1.37: 1.The majority of children (80%) was under 1 year old of age, 72.5% with malnutrition, and 24.8% with severe malnutrition. Clinical symptoms mostly found were difficulty of breathing (98%), fever (85.2%), cough (75.2%), and runny nose (63.1%). The most common types of CHD were Patent Ductus Arteriosus (47.6%), followed by Ventricular Septal Defect (47%). Bronchopneumonia (86.6%) was the common type of ALRTI. The length of stay was mostly less than 10 days (70.5%). From all the children 43.7% had complications, and 6.7% died.Conclusions: The ALRTI in children with CHD is not common and has good outcome. The majority for CHD lesions are Patent Ductus Arteriosus and Ventricular Septal Defect while for ALRTI is Bronchopneumonia. DOI: 10.15850/amj.v2n3.483

Comparison of Age of Thelarche between Obese and Normal Girls Yunitasari Yunitasari; R.M. Ryadi Fadil; Fenny Dwiyatnaningrum
Althea Medical Journal Vol 3, No 3 (2016)
Publisher : Faculty of Medicine Universitas Padjadjaran

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Background: Childhood obesity has become a major concern in recent years. The increasing childhood obesity prevalence may occur as the result of food consumption with high content of calories, fat, cholesterol and the lack of physical activity. Obesity in children will also affect their pubertal development. Puberty is a period in which maturation of the reproductive function is achieved.In girls, the initial sign of puberty is thelarche, defined as the appearance of breast bud underneath the areola.The onset of puberty depends on many factors, one of them is nutritional status especially obesity. This study was conducted to compare the age of thelarche between obese and normal girls.Methods: An analytical study using cross sectional method was conducted. This study was held in Bandung, West Java, Indonesia, during the period of SeptemberOctober 2013. Data were obtained from 3 elementary schools, selected by multistage random sampling.The total subject was 46. Data were analyzed using the Mann-Whitney and chi-square test.Results: Thelarche occurred at age 9 years 4 months in the obese group compared to 11 years 2 months in the normal group. The analysis using Mann-Whitney test showed the difference was statistically significant (p<0.001). Based on age group, 42% obese girls attained thelarche between ages 89 years, while 63% girls in the normal group attained thelarche between ages 1112 years. The analysis using chi- square test showed that the difference was statistically significant (p<0.001).Conclusions: Thelarche occurs earlier in obese girls compared to normal girls. [AMJ.2016;3(3):411–5]DOI: 10.15850/amj.v3n3.906

Frequency and Clinical Characteristics of Tympanic Membrane Perforation Outpatients at Dr. Hasan Sadikin General Hospital in 2011–2013 Veronika Ratih M.; Sally Mahdiani; Fenny Dwiyatnaningrum
Althea Medical Journal Vol 3, No 1 (2016)
Publisher : Faculty of Medicine Universitas Padjadjaran

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Background: Tympanic membrane perforation is a hearing problem that has become a health problem in the society. In Indonesia, there are only a few studies regarding tympanic membrane perforation. This study was aimed to observe the frequency and clinical characteristics of tympanic membrane perforation patients.Methods: This was a descriptive study performed from August to September 2014. The data was taken retrospectively from medical records of tympanic membrane perforation patients at Dr. Hasan Sadikin General Hospital from January 2011 to December 2013.Results: Of 579 tympanic perforation patients, there were only 214 medical records met the inclusion criteria. The frequency of tympanic membrane perforation patients increased in 2011 it was 28%, in 2013 it was 37.6%. The number of male patients (53.3%) was higher than female patients’. Most patients were in productive age (83.2%). Most patients came with the chief complaint of discharge from ear (36.4%) and the most common etiology was infection (84.1%). Otological examination showed that most patients had unilateral perforation (73.8%). Based on the size of perforation, central perforation (52.3%) was the most common otological finding. From audiogram, most patients had conductive hearing loss (41.5%) with moderate degree of hearing loss (30.4%). Most patients were treated by medications (64.5%).Conclusions: The frequency of tympanic membrane steadily increases with clinical characteristic mostly in male patients in productive age admitted with chieft complain of discharge of ear. The most common etiology is infection. Majority of patients have unilateral central perforation that cause conductive hearing lost. [AMJ.2016;3(1):43–8] DOI: 10.15850/amj.v3n1.702

A Study of Hypoalbuminemia and Pleural Effusionin Pediatric Nephrotic Syndrome Tovan Perinandika; Dedi Rachmadi; Fenny Dwiyatnaningrum
Althea Medical Journal Vol 4, No 2 (2017)
Publisher : Faculty of Medicine Universitas Padjadjaran

Background: Nephrotic syndrome (NS) is a kidney disease that is most often found in children. Hypoalbuminemia in NS can cause a decrease in oncotic pressure causing extravasation of fluid into the interstitial space. In conditions of severe hypoalbuminemia, fluid extravasation may cause occurrence of pleural effusion. The objectives of this study was to analyze the correlation between hypoalbuminemia and pleural effusion in children with NS. Methods: An analytical study was conducted on 69 medical records of pediatric nephrotic syndrome from 1 January 2008–31 December 2013 in dr. Hasan Sadikin General Hospital. Inclusion criteria were pediatric patients between 1-14 years old with NS. Exclusion criteria were patients who already had albumin transfusion, malnutrition, patients with chronic disease, and incomplete medical record information. Contingency coefficient test was carried out to discover the correlation between variables. Results: Out of 89 samples, 69 samples were included. Characteristics of the included patients are male (n=48), female (n=21), age 1–5 (n=24), 6–10 (n=22), 11–14 (n=23), mild hypoalbuminemia (n=3), moderate hypoalbuminemia (n=27), severe hypoalbuminemia (n=39), patients with pleural effusion (n=23), and non-pleural effusion (n=46). There was a significant correlation between hypoalbuminemia and pleural effusion with p=0.000 (p<0.05) and moderate correlation (r=0.437). Conclusions: Hypoalbuminemia has correlation with pleural effusion in pediatric nephrotic syndrome.Keywords: Hypoalbuminemia, pediatric nephrotic syndrome, pleural effusionDOI: 10.15850/amj.v4n2.1075

Quality of Life in Children with Atopic Dermatitis Muhammad Akbar Wicaksana; Oki Suwarsa; Fenny Dwiyatnaningrum
Althea Medical Journal Vol 4, No 3 (2017)
Publisher : Faculty of Medicine Universitas Padjadjaran

Background: Atopic dermatitis (AD) is the most common chronic skin disease in children which caused significant morbidity and impaired quality of life (QoL). The main goal of AD therapy is to prevent flare -ups, prolong remission and increase QoL. Therefore, the study aimed to discover QoL in children with AD.Methods: The study was conducted at Pasundan Public Health Centre, Al Islam General Hospital and Kimia Farma Private Dermatology Clinic, from September to November 2015. This descriptive study used consecutive sampling with 24 outpatients who were admitted to the health facility and diagnosed as AD. A questionnaire on Infant Dermatitis Quality of Life for infants aged 0–4 years, and Children Dermatology Life Quality Index for children aged 5–16 years was used in this study to measure QoL.Results: Out of 24 patients, 9 patients aged 0–4 years had mean score of 4.44±4.36, and 15 patients aged 5–16 years had mean score of 5.80±3.95. Mean SCORAD Objective in patients aged 0–4 and 5–16 was 15.61±7.75 and 17.44±11.Conclusions: The QoL in children with AD vary among patients. Most of the patients have mild-moderate impairment in QoL.

Pseudoexfoliation Glaucoma in the National Eye Center, Cicendo Eye Hospital, January–October 2012 Rizki Fasa Ramdhani; Elsa Gustianty; Fenny Dwiyatnaningrum
Althea Medical Journal Vol 2, No 1 (2015)
Publisher : Faculty of Medicine Universitas Padjadjaran

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Background: Pseudoexfoliation syndrome is characterized by the deposition of a distinctive fibrillar material in the anterior segment of the eye. This condition is a major risk factor for development of glaucoma, termed pseudoexfoliation glaucoma (PEXG). The aim of this study was to describe the characteristic and management of PEXG in the National Eye Center Cicendo Eye Hospital.Methods: A descriptive retrospective study was conducted in October–November 2012 using medical records of PEXG patients in the National Eye Center Cicendo Eye Hospital during January–October 2012. Results: There were 32 patients (43 eyes) diagnosed as PEXG, most of them were male (78.1%), age 70–74 years old (34.4%) and followed by those in the range of age 65–69 years old (21.9%). Most of the cases were unilateral (65.6%) decrease of visual acuity less than 3/60 (76.7%), increase of intraocular pressure (IOP) with majority in the range of 31–40 mmHg (32.6%) and 41–50 mmHg (32.6%), Cup/Disc Ratio 0.9–1.0 (46.51%) and followed by those classified as majority which were hard to assess because of the presence of opaque media (34.89%). The type of glaucoma was open angle glaucoma (88.4%). The treatment received was a combination of two types of antiglaucoma medication and surgery IOPConclusion: PEXG is mostly found in elderly patients. While most of the patients come with high IOP and late stage of the disease IOPKeywords: Characteristics, glaucoma, pseudoexfoliation DOI: 10.15850/amj.v2n1.446

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