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Hand hygiene, health care workers, methicillin-resistant Staphylococcus aureus, nosocomial infection, Staphylococcus aureus Julius Gunadi; Herri S. Sastramihardja; Nina Susana Dewi
Althea Medical Journal Vol 2, No 2 (2015)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (489.362 KB)

Abstract

Background: Hypercholesterolemia is a major risk factor for coronary heart disease. Ear fungus (Auricularia auricula) contains soluble fiber (beta glucan) which is believed to have an effect of reducing cholesterol level. The aim of this study was to determine the effect of fungus infusion in reducing blood cholesterol.Methods: This study used the laboratory experimental method conducted in the pharmacology laboratory of Dr. Hasan Sadikin General Hospital Bandung. The subjects were 25 male Wistar rats which were randomly divided into 5 groups. The first group was given only distilled water as a negative control, the remaining groups were induced to be dyslipidemic and received fungus infusion with different doses of 18%, 36%, 72% and one group received no treatment.Results: The comparison of different doses showed all had the effect of reducing cholesterol levels compared to the positive control group (p<0.05). Each dose showed slight differences in their effectiveness, 18% (p=0.007; p<0.05), 36% (p=0.002; p<0.05), and 72% (p=0.014; p<0.05).Conclusions: ear fungus infusion had the effect of reducing cholesterol with the most effective concentration was 36%. [AMJ.2015;2(1):153–61]
HASIL HITUNG NORMOBLAS ANTARA SEDIAAN HAPUSAN DARAH TEPI PENDERITA AML DENGAN ALL Hidayat .; Nina Susana Dewi; Nadjwa Zamalek Dalimoenthe
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol 16, No 1 (2009)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v16i1.997

Abstract

Normoblast is an immature form of erythrocyte in erythropoietin system. Normally, normoblast can be found in peripheral blood healthy neonates. The existence of normoblast in peripheral blood might be the sign of pathologic conditions such as hemolytic anemia,acute blood loss, and ischemia and bone marrows abnormalities like malignancy or leukemia. In acute leukemia (Acute MyeloblasticLeukemia and Acute Lymphoblastic Leukemia), normoblast existence in peripheral blood may due to erythropoietin system suppression.The aim of this study is to compare normoblast count between AML and ALL, and also to find out the correlation between leukocyte andnormoblast count in AML and ALL. The subject of this study were patient diagnosed as AML (30) and ALL (30) in Hematology Divisionof Clinical Pathology Department at Dr.Hasan Sadikin Hospital Bandung in July 2006–August 2008. In this study we examined 30peripheral blood smears from AML and 30 peripheral blood smears from ALL. Leukocyte count result was derived from CBC performedwith Sysmex KX-21. The mean value of normoblast count from AML blood smear patients is 1930.60 (3.60/100 WBC) while ALL bloodsmear patients is 309.60 (0.43/100 WBC). Statistically this difference is significant (p < 0.001). There are strong correlation betweenleukocyte count and normoblast count within both group (r = 0.851, r = 0.948; p < 0.001).