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All Journal E-Jurnal Medika Udayana Damianus Journal of Medicine Jurnal Biomedika dan Kesehatan Medica Hospitalia Medika Alkhairaat : Jurnal Penelitian Kedokteran dan Kesehatan JURNAL Al-AZHAR INDONESIA SERI SAINS DAN TEKNOLOGI Jurnal EnviScience (Environment Science) Bali Dermatology and Venereology Journal Indonesian Journal of Pharmaceutical and Clinical Research Journal of Holistic and Traditional Medicine (JHTM) Insights in Public Health Journal NUCLEUS: Jurnal Sains dan Teknologi International Islamic Medical Journal Cermin Dunia Kedokteran GENIUS JOURNAL (General Nursing Science Journal) Journal of Pharmaceutical Care and Sciences
Reqgi First Trasia
Dept. Of Parasitology, Faculty Of Medicine, Sultan Ageng Tirtayasa University, Cilegon, Banten, Indonesia
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Dentistry Education Electrical & Electronics Engineering Engineering Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Library & Information Science Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Physics Public Health

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Respon imun hospes terhadap Sarcoptes scabiei Trasia, Reqgi First; Sari, Ika Puspa
Jurnal Biomedika dan Kesehatan Vol 3 No 4 (2020)
Publisher : Fakultas Kedokteran Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/JBiomedKes.2020.v3.183-192

Abstract

Skabies, penyakit kulit yang disebabkan oleh infestasi dan sensitisasi terhadap tungau Sarcoptes scabiei var. hominis dan produknya, masih menjadi masalah kesehatan di dunia, termasuk Indonesia. World Health Organization (WHO) atau Organisasi Kesehatan Dunia pada tahun 2017 menyatakan bahwa skabies termasuk dalam Neglected Tropical Disease (NTD) yang memerlukan pengontrolan skala besar. S. scabiei spesifik terhadap hospes dan hal tersebut akibat perbedaan fisiologis tungau dan variabel hospes seperti diet, bau, respon imun, dan faktor-faktor fisik. Manifestasi klinis pada manusia berupa inflamasi kulit akan timbul lebih dari 4 minggu setelah terinfestasi. Lambatnya respon imun itu adalah efek dari kemampuan S.scabiei dalam memodulasi berbagai aspek respon imun dan inflamasi hospes. Telur, feses, ekskreta, saliva, dan tubuh S.scabiei yang mati juga menstimulasi respon imun. S.scabiei mendorong keluarnya anti-inflammatory cytokine interleukin-1 receptor antagonist (IL-1ra) dari sel fibroblas manusia. IL-1ra menginhibisi sitokin proinflamasi IL-1 dengan mengikat reseptor IL-1 yang ada dalam sel limfosit T, sel limfosit B, natural killer cell, makrofag dan neutrofil. Berdasarkan patogenesis skabies, antigen tungau merangsang respon imun adaptif pada manusia agar muncul produksi imunoglobulin. Pengetahuan mengenai respon imun hospes terhadap Sarcoptes scabiei ini dapat dijadikan dasar untuk pengembangan metode serodiagnostik dalam rangka menegakkan diagnosis skabies, sehingga membantu eliminasi skabies di Indonesia.
Trends in diagnostic approach of scabies as a neglected tropical disease Trasia, Reqgi First
Bali Dermatology and Venereology Journal Vol 3, No 1 (2020)
Publisher : DiscoverSys Inc

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15562/bdv.v3i1.26

Abstract

Scabies is a parasitic disease of the skin that is difficult to enforce if the clinical symptoms are not typical. The diagnosis relies on clinical symptoms to be less efficient and only has a sensitivity of less than 50% because it is difficult to distinguish active infestations, residual skin reactions, or reinfestations. Misdiagnosis results in wrong treatment and causes the patient to not recover and continues to be a source of infection for the environment. The exact diagnosis of scabies is determined by finding mites or eggs on laboratory tests, but mites are difficult to find because only a few mites infest sufferers. For this reason, various studies in the world have tried to develop diagnostic methods in the enforcement of scabies. This article will describe the trend of establishing a diagnosis of scabies, as well as the advantages and disadvantages in its application.
Rational Use of Medicine in the Treatment of Helminth Infection : A Mini Review Trasia, Reqgi First
Indonesian Journal of Pharmaceutical and Clinical Research Vol. 4 No. 1 (2021): Indonesian Journal of Pharmaceutical and Clinical Research
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/idjpcr.v4i1.5375

Abstract

Indonesia still has health problem, especially soil transmitted helminth. These helminths can cause deteriorate health, nutrition, intelligence and productivity of patients so causes a lot of losses economically. The aim of this article is to review the rational treatment of helminth infection. Albendazole, mebendazole, and pyrantel pamoate are the drugs recommended by the WHO. However, the uses of the three are different, especially for mass treatment or selective medicine. This review conclude that the three drugs are used according to the target patient's age with dosages and preparations that must be adjusted.
Scabies: Treatment, Complication, and Prognosis Trasia, Reqgi First
Cermin Dunia Kedokteran Vol 48, No 12 (2021): General Medicine
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (94.534 KB) | DOI: 10.55175/cdk.v48i12.1575

Abstract

Scabies is a skin infestation caused by Sarcoptes scabiei mite. In 2017, WHO included scabies in the list of neglected tropical diseases. Treatment of scabies is currently still problematic due to late diagnosis and not properly managed complications.Skabies adalah penyakit kulit yang disebabkan oleh tungau Sarcoptes scabiei. Pada tahun 2017, WHO menggolongkan skabies dalam daftar penyakit tropis yang terabaikan. Pengobatan skabies saat ini masih bermasalah karena keterlambatan diagnosis. Komplikasinya pun tidak ditangani dengan baik. 
EPIDEMIOLOGY UPDATE OF HELMINTHIASIS IN INDONESIA Reqgi First Trasia
Insights in Public Health Journal Vol 2 No 1 (2021): Insights in Public Health Journal
Publisher : Public Health Department, Faculty of Health Sciences, Jenderal Soedirman University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.iphj.2021.2.1.4283

Abstract

Helminthiasis are still a health problem in Indonesia. Although not deadly, helminth infections will slowly affect children's health and productivity through a decrease in nutritional status. The chronic clinical course and tend to be asymptomatic causes helminthiasis to be classified as a neglected tropical disease. Research on the epidemiology of helminthiasis has been carried out in several regions in Indonesia. However, there has not been a comprehensive review to see the epidemiology aspects of helminthiasis. This article will discuss in detail how helminth infections influence the host to increase the incidence of malnutrition and its impact on children's health. Although this is not an emergency and a condition, the risk factors will lead the child to a state of chronic helminthiasis and transmission to other children which will have a negative impact on public health.
Scabies in Indonesia: Epidemiology and Prevention Reqgi First Trasia
Insights in Public Health Journal Vol 1 No 2 (2020): Insights in Public Health Journal
Publisher : Public Health Department, Faculty of Health Sciences, Jenderal Soedirman University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.iphj.2020.1.2.3071

Abstract

Scabies is still a health problem in the world, including Indonesia. The World Health Organization (WHO) in 2017 stated that scabies is included in the Neglected Tropical Disease (NTD) which requires large-scale control. In Indonesia, according to data from the Ministry of Health Republic of Indonesia the prevalence of scabies in 2017 is 6% of the total population in Indonesia. Discussion on the incidence and prevention of scabies from various regions in Indonesia so far is still not comprehensive. This review will provide an overview related to epidemiology and preventive measures against scabies so that scabies cases in Indonesia can be controlled properly
Dampak Lingkungan Terhadap Kejadian Infeksi Parasit Reqgi First Trasia
Jurnal EnviScience (Environment Science) Vol 5, No 1 (2021): Public Health, Food and Environmental Sectors Supporting Global Health Quality
Publisher : Universitas Islam Lamongan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30736/5ijev.v5iss1.244

Abstract

Penyakit infeksi parasit masih menjadi masalah kesehatan di Indonesia dan di dunia. Pada tahun 2017, World Health Organization (WHO) memasukkan beberapa penyakit parasit ke dalam Neglected Tropical Disease (NTD). Penyakit parasit tidak dapat lepas dari kondisi lingkungan, suhu, kelembaban, iklim, dll. Di Indonesia, masih sedikit artikel yang meninjau dampak lingkungan terhadap insiden infeksi parasit. Tujuan dari penulisan artikel ini adalah untuk membahas bagaimana suhu, kelembaban dan cuaca dapat memengaruhi angka prevalensi penyakit akibat parasit.
Pengaruh Lingkungan Terhadap Transmisi Infeksi Protozoa Reqgi First Trasia
Jurnal EnviScience (Environment Science) Vol 5, No 2 (2021): Implementing the Quality of Environmental Health as a 2030 Sustainable Developme
Publisher : Universitas Islam Lamongan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30736/5ijev.v5iss2.276

Abstract

Amebiasis and other protozoal infectious diseases occur worldwide. The highest prevalence is especially in the tropics and subtropics, especially in countries with poor environmental sanitation conditions. In Indonesia, colonic amebiasis is found in endemic conditions with a prevalence of about 18%. Epidemiological research shows that lack of hygiene is a factor that influences the occurrence of infection. In free-living amoeba, the spread can be through fresh water, soil, and feces because this amoeba is thermophilic. The amoeba is commonly found in water contaminated with E.coli. Several other types of protozoa were found to be cosmopolitan, so one form of prevention is by chlorinating drinking water sources using the coagulation-sedimentation-filtration method. In addition, environmental temperature also plays a role in the life cycle of the protozoa. Outside their habitat, protozoa can die at a temperature of 50 C, but can live for 5 days at a temperature of 0 C. Protozoa can also die in culture at a pH of less than 4.9 and cannot live in an aerobic environment. In parasites belonging to sporozoa, oocysts die at a temperature of 45-55 C or when dried and mixed with formalin, ammonia, and iodine solution.
THE ROLE OF FORENSIC ENTOMOLOGY IN ESTIMATING THE TIME OF DEATH Reqgi First Trasia
Bahasa Indonesia Vol 21 No 1 (2022): Damianus Journal of Medicine
Publisher : Atma Jaya Catholic University of Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25170/djm.v21i1.1686

Abstract

It takes dedication and thoroughness in uncovering the various mysteries behind forensic cases. Various methods will be needed in answering various questions related to these cases, and it is imperative that the evidence or expert testimony is can be accounted for. Over time, some of the evidence, especially human body tissue will undergo a process of degradation and eventually disappear. However, for a forensic entomologist, the damage and loss of body tissue can bring new evidence. Evidence which of course can be justified scientifically at court. Like when alive, the tissues of the human body after death remain attractive to them various types of insects. Different types of insects will be attracted at different stages from the decay stages of human tissue. These insects follow a development patterns. Related to knowledge about growth and development them, it can be used to make an estimate of how long it has been since the body has been dead. In addition, the identification of the above will also indicate whether a corpse has been moved from one area to another.
GAMBARAN ASPEK LINGKUNGAN DAN PERILAKU PENCEGAHAN PENULARAN TUBERKULOSIS PARU DI WILAYAH KERJA PUSKESMAS BEBANDEM, KABUPATEN KARANGASEM Reqgi First Trasia; Putu Aryani
E-Jurnal Medika Udayana vol 3 no 9 (2014):e-jurnal medika udayana
Publisher : Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (148.544 KB)

Abstract

Tuberkulosis merupakan infeksi yang disebabkan Mycobacterium tuberculosis, dan ditularkan melalui perantara udara. Di Puskesmas Bebandem, tahun 2011 dan 2012 tercatat terdapat 39 dan 27 kasus tuberkulosis paru dengan hasil tes bakteri tahan asam (BTA) positif, sedangkan sejak bulan Januari sampai Juni 2013 terdapat 26 kasus baru tuberkulosis, dimana 25 kasus adalah tuberkulosis paru dan 1 kasus tuberkulosis ekstrapulmoner.Terkait dengan permasalahan tersebut, telah dilakukan penelitian yang bertujuan untuk mengetahui gambaran aspek lingkungan dan perilaku pencegahan penularan tuberkulosis paru di wilayah kerja Puskesmas Bebandem.Penelitian ini merupakan studi deskriptif cross-sectionaldengan jumlah sampel sebanyak 18 responden, yaitu semua penderita TB paru di wilayah kerja Puskesmas Bebandem.Data diperoleh melalui wawancara dengan menggunakan kuesioner terstruktur.Data yang diperoleh dianalisis secara deskriptif yang disajikan menggunakan tabel dan narasi.Berdasarkan hasil penelitian, dapat diketahui bahwa sebagian besar TB paru di wilayah kerja Puskesmas Bebandem berada pada kelompok usia produktif (66,7%) dengan tingkat pendidikan rendah (72,2%), tidak bekerja (55,6%), dengan status sosial menengah ke atas. Sebagian besar penderita TB paru yang menjadi sampel penelitian di Puskesmas Bebandem memiliki ventilasi yang tidak memenuhi syarat rumah sehat (50%), jendela rumah dengan pencahayaan kurang (66,7%), dan merupakan perokok pasif (55,6%). Akan tetapi, sebanyak 66,7% sampel telah menerapkan perilaku pencegahan penularan TB paru dengan benar. Berdasarkan beberapa temuan dalam penelitian tersebut, maka dipandang perlu untuk dilakukan kegiatan pendampingan dan penyuluhan mengenai pentingnya memiliki ventilasi dan jendela yang memenuhi syarat rumah sehat, serta menghindari paparan asap rokok.  
Co-Authors Ika Puspa Sari Putu Aryani