Claim Missing Document
Check
Articles

Found 5 Documents
Search
Journal : Tropical Health and Medical Research Journal

Effectiveness of Cinnamon (Cinnamomum burmannii) Ethanol Extract Against Staphylococcus aureus Growth Nurul Huda; Ratih Dewi Dwiyanti; Anny Thuraidah
Tropical Health and Medical Research Vol. 1 No. 2 (2019): Tropical Health and Medical Research
Publisher : Baiman Bauntung Batuah Center

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (314.614 KB) | DOI: 10.35916/thmr.v1i2.6

Abstract

Cinnamon (Cinnamomum burmannii) is widely used by the public as a food ingredient and contains chemical compounds such as alkaloids, flavonoids, polyphenols, saponins, and terpenoids which function as an antibacterial against Staphylococcus aureus. This study aims to determine the Minimum Inhibitory Concentration and Minimum Bactericidal Concentration of cinnamon ethanol extract on Staphyloccocus aureus. This research is experimental with posttest only control group design through the tube dilution method. The results of the Minimum Inhibitory Concentration (MIC) study showed no clarity at concentrations of 30% and 40%. The results of the Minimum Bactericidal Concentration (MBC) obtained the number of colonies at a level of 10% by 51 CFU / plate, 20% by 27 CFU / plate, 30% by 6 CFU / plate and 40% by 0 CFU / plate. Based on the results of this study concluded that MIC cinnamon ethanol extract was 30%, and MBC cinnamon ethanol extract was 40%.
Citrus hystrix D.C Juice Inhibits The Growth of Staphylococcus aureus Novina Kusumawardhani; Anny Thuraidah; Nurlailah Nurlailah
Tropical Health and Medical Research Vol. 2 No. 1 (2020): Tropical Health And Medical Research
Publisher : Baiman Bauntung Batuah Center

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (403.587 KB) | DOI: 10.35916/thmr.v0i0.17

Abstract

Citrus hystrix D.C. is a citrus-type citrus tribal plant, one of the most favored and developed fruits by the people of South Kalimantan Indonesia. Citrus hystrix D.C. contains useful chemical compounds, one of which is flavonoids, which function as antibacterial and play a critical role in inhibiting bacterial growth. The purpose of this study was to determine the antibacterial activity of Citrus hystrix D.C. juice at 25%, 50%, 75%, and 100% concentration on the growth of Staphylococcus aureus. This research is experimental with Posttest Only Control Group Design. The material used was local Citrus hystrix D.C., fresh and clean green, obtained from the Astambul area, Banjar Regency, South Kalimantan Indonesia. The results showed that there was a zone of inhibition of Citrus hystrix D.C. juice on Staphylococcus aureus growth which began at 25%, 50%, 75% and 100% concentrations of 13.75mm, 17.25mm, 19.75mm, and 21.75mm, so it can conclude that the juice of Citrus hystrix D.C. influences the growth of Staphylococcus aureus which has the largest inhibitory zone at a concentration of 100%.
Garlic Extract (Allium sativum L.) Effectively Inhibits Staphylococcus aureus and Escherichia coli by Invitro Test Agnina Listya Anggraini; Ratih Dewi Dwiyanti; Anny Thuraidah
Tropical Health and Medical Research Vol. 2 No. 2 (2020): Tropical Health and Medical Research
Publisher : Baiman Bauntung Batuah Center

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (258.775 KB) | DOI: 10.35916/thmr.v0i0.22

Abstract

Infection is a disease caused by the presence of pathogenic microbes, including Staphylococcus aureus and Escherichia coli. Garlic (Allium sativum L.) has chemical contents such as allicin, alkaloids, flavonoids, saponins, tannins, and steroids, which can function as an antibacterial against Staphylococcus aureus and Escherichia coli. This study aims to determine the antibacterial properties of garlic extract powder against Staphylococcus aureus and Escherichia coli. This research is the initial stage of the development of herbal medicines to treat Staphylococcus aureus and Escherichia coli infections. The antibacterial activity test was carried out by the liquid dilution method. The concentrations used were 30 mg/mL, 40 mg/mL, 50 mg/mL, 60 mg/mL and 70 mg/mL. The results showed that the Minimum Inhibitory Concentration (MIC) against Staphylococcus aureus and Escherichia coli was 40 mg/mL and 50 mg / mL. Minimum Bactericidal Concentration (MBC) results for Staphylococcus aureus and Escherichia coli are 50 mg/mL and 70 mg/mL. Based on the Simple Linear Regression test, the R2 value of Staphylococcus aureus and Escherichia coli is 0.545 and 0.785, so it can be concluded that there is an effect of garlic extract powder on the growth of Staphylococcus aureus and Escherichia coli by 54.5% and 78.5%. Garlic (Allium sativum L.) extract powder has potential as herbal medicine against bacterial infections but requires further research to determine its effect in vivo.
Fungicidal Effects of Chloroform Extract of Red Galangal (Alpinia purpurata (Vieill.) K. Sch) on the Growth of Trichophyton rubrum Nur Asy Syifa Azizah; Anny Thuraidah; Ratih Dewi Dwiyanti
Tropical Health and Medical Research Vol. 4 No. 1 (2022): Tropical Health and Medical Research
Publisher : Baiman Bauntung Batuah Center

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35916/thmr.v4i1.59

Abstract

Trichophyton rubrum is the most common causative agent of anthropophilic dermatophytosis worldwide. Treatment of dermatophytosis can use natural ingredients. In Indonesia, several medicinal plants have been used, one of which is red galangal (Alpinia purpurata (Vieill.) K. Sch). This study aims to determine the effectiveness of red galangal rhizome chloroform extract on the growth of Trichophyton rubrum. This study is a True Experiment study with Posttest Only With Control Group Design consisting of 8 treatments namely positive control, extract control, 0 mg/mL (negative control), 20 mg/mL, 30 mg/mL, 40 mg/mL, 50 mg/ml, and 60 mg/mL extract of red galangal rhizome chloroform with 3 repetitions. The antifungal activity test was carried out using the determination of Minimum Inhibitory Concentration (MIC), Minimum Fungicidal Concentration (MFC), and Bioautography Test. The results showed that the red galangal rhizome chloroform extract in the Agar Overlay Bioautography Test contained an inhibition zone on the growth of Trichophyton rubrum. The determination of MIC and MFC were 20 mg/mL and 40 mg/mL, respectively. The study concludes that the red galangal rhizome chloroform extract affects the growth of the fungus Trichophyton rubrum. Research can be continued by knowing more specifics about the bioactive compounds from the red galangal rhizome, which have antifungal activity against Trichophyton rubrum.
Analysis of Urea Levels of Banjarmasin Ministry of Health Polytechnic Students Survivors of Covid 19 Siti Nur Shalehah Hasanah; Anny Thuraidah; Haitami Haitami
Tropical Health and Medical Research Vol. 5 No. 2 (2023): Tropical Health And Medical Research
Publisher : Baiman Bauntung Batuah Center

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35916/thmr.v5i1.97

Abstract

Corona Virus Disease 2019 (Covid-19) is an infection caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). Drug therapy for Covid-19 patients currently uses broad-spectrum antivirals such as Remdesivir, Favipiravir, and Oseltamivir, which have side effects of impaired kidney function with a marked increase in serum urea levels. The study aims to analyze the relationship between antiviral administration and serum urea levels of Covid-19 survivors with student respondents from the Health Polytechnic of the Ministry of Health, Banjarmasin, Indonesia. The research method is an analytic survey with a case-control design. Samples were taken using the purposive sampling method and obtained from 10 respondents who were confirmed positive for Covid-19 who consumed antivirals, ten respondents who were confirmed positive for Covid-19 did not consume antivirals, and ten respondents who were not confirmed positive for Covid-19. The Urea test method uses the Rayto Chemray 120 Clinical Analyzer. The results showed that the average urea level of respondents who confirmed positive for Covid-19 who consumed antivirals was 37.35 mg/dl, and respondents who confirmed positive for Covid-19 who did not consume antivirals was 30.70 mg/dl. Respondents who were not confirmed for Covid-19 19 are 30.97 mg/dl. The study's conclusion showed a relationship between the administration of antivirals and serum urea levels of Covid-19 survivors. Suggestions for further research are to use different parameters in assessing the kidney function of Covid 19 survivors, such as creatinine and blood urea nitrogen.