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All Journal journal of internal medicine Buletin Udayana Mengabdi E-Jurnal Medika Udayana E-Jurnal Udayana Medica Indonesian Journal of Clinical Pathology and Medical Laboratory (IJCPML)
Dewa Ayu Putu Rasmika Dewi
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Biochemistry, Genetics & Molecular Biology Education Health Professions Medicine & Pharmacology Neuroscience

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PROFIL ANALISIS BATU SALURAN KENCING DI INSTALASI LABORATORIUM KLINIK RSUP SANGLAH DENPASAR Rasmika Dewi, Dewa Ayu Putu; Ngurah Subawa, Anak Agung
journal of internal medicine Vol. 8, No. 3 September 2007
Publisher : journal of internal medicine

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Abstract

Urolithiasis is a pathological condition that is caused by the formation of hard mass like stone along theurinary tract. Identification of the urinary stones can be done through chemical analysis or using of infraredspectroscopy. The semiquantitative methods used to analyze are titrimetric and colorimetric. This study wascross sectional whose results were descriptive. The data used in this study was 113 urinary stone analysisrecords taken from Routine Clinic of Laboratory Clinic Installation at Sanglah Hospital in period January untilDecember 2007 (one year). The prevalence of urolithiasis in males were more than females (4:1) and it wasmostly occur in age range 40-60 years old of both sexes. Generally, more than one kind of stone compositionswere found in a patient of urolithiasis, the dominant was calcium oxalate.
PEMERIKSAAN KADAR GULA DARAH SEWAKTU PADA MASYARAKAT DUSUN SAMU MAMBAL KABUPATEN BADUNG D.A.P. RASMIKA DEWI
Buletin Udayana Mengabdi Vol 7 No 2 (2008): Volume 7 No.2 – September 2008
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat

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ABSTRACT The measurement of random blood sugar (BSN) for people of Banjar Samu at Desa Mekar Buana Mambal in Badung Regency, aimed for screening Diabetes Mellitus (DM) disease as effort for early detection of this disease. Otherwise the counseling of DM aimed to increase the people knowledge. The increasing people knowledge about DM was expected to change the people behaviors, so this disease can be prevented, especially at people that have high risk factors. Otherwise, in the people that has been suffered DM, we have expected the blood sugar concentration would be more controllable and the medication would give more satisfying result. The early detection of DM by this screening, have expected to degrade the risk of disease complications, improved live quality, and lengthen the age of the patients.This activities had been done on Monday, September 15th 2008 from 09.00 a.m. until finish, in Bale Banjar Samu, Desa Mekar Buana Mambal, Badung Regency. The term of this activity was counseling and free of charges BSN measurement, for people of Banjar Samu, consist both women and men. The counseling had been given by Dr. dr. I Wayan Putu Sutirta Yasa, MSi., represent the Supervisor of Clinical Immunology at Sanglah Hospital Clinical Laboratory Installation. Free of charges measurement consisted of body weight, blood pressure, and BSN from 97 people of Banjar Samu, which age range from 26 year’s until 80 year’s old. From 97 people of Banjar Samu that had been checked, we founded 3 people with the BSN concentration 293 mg/dl, 384 mg/dl, and 210 mg/dl that mean exceeding normal mark (< 200 mg/dl).
IMMUNOPATOGENESIS INFEKSI VIRUS DENGUE IBN Dwipayana Manuaba; I Wayan Putu Sutirtayasa; DAP Rasmika Dewi
E-Jurnal Medika Udayana vol 2 no 10 (2013):e-jurnal medika udayana
Publisher : Universitas Udayana

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Dengue , adalah penyakit arboviral tersering yang tersebar di seluruh dunia. Dengue disebabkan oleh infeksi 1 dari 4 serotipe virus dengue. Virus dengue berasal dari keluarga Flaviviridae , genus Flavivirus ( virus RNA ikatan-tunggal tidak ber-segmen).Virus dengue menular ke manusia melalui gigitan nyamuk Aedes betina yang telah ter-infeksi. Virus dengue (DEN) mempunyai 4 serotipe (DEN-1 , DEN-2 , DEN-3 , DEN-4) . infeksi dari salah satu tipe virus bisa tanpa gejala di mayoritas kasus yang terjadi atau bisa menimbulkan gejala klinis. Mulai dari yang ringan dengan gejala seperti flue (yang biasa disebut demam dengue [DF] ) , bentuk yang lebih parah (yang biasa disebut demam berdarah [DHF]) , dan yang hingga menimbulkan gejala syok ( dengue syok sindrom [DSS]). Penyebab dari perkembangan dan mekanisme yang terlibat dalam patofisiologi penyakit infeksi DENV tidak bisa dengan jelas didefinisikan. Immunopatogenesis infeksi virus dengue membahas tentang jalan masuk DENV , aktivasi berlebihan imune yang menyimpang dan menginduksi autoantibody , respon humoral ,peningkatan dependen antibody
ANEMIA SEL SABIT Gede Agus Suwiryawan; I Wayan Putu Sutirta Yasa; DAP Rasmika Dewi
E-Jurnal Medika Udayana vol 2 no 9 (2013):e-jurnal medika udayana
Publisher : Universitas Udayana

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Abstract

Anemia is a form of blood disorder most often occurs in the community. Sickle cell anemia is anemia due to hemoglobinopathy caused by a change in the amino acid-6 of the ? globin chain. Sickle cell anemia is common in tropical areas of Africa and some parts of the region Saudi Arabia, India and the Mediterranean as well as black people in America. In addition there are also careers in various European countries. In pathophysiology, there are amino acid change from glutamic acid to valine in the ?-globin chain that causes red blood cells become sickle-shaped when deoxygenatied, but still be able to return to its normal shape when experiencing oxygenation. When the red blood cell membrane have been amended, the polymerization of red blood cells has become irreversible. Clinical picture seen in sickle cell anemia can be divided into two, namely: acute and chronic. Diagnosis can be done is to distinguish between heterozygous or homozygous sickle cell. Treatment provided in accordance with the clinical picture appears. Treatment that can be done is by blood transfusion, bone marrow transplant, anti-sickling drug delivery, and drug delivery to trigger the synthesis of HbF. Treatment still in the development stage is to use stem cells.
IMMUNOPATHOGENESIS OF DENGUE SHOCK SYNDROME Karta Sawenda; I Wayan Putu Sutirta Yasa; DAP Rasmika Dewi; Bagus Komang Satriyasa
Bali Journal of Medical and Health Sciences vol 1no1 2013
Publisher : Faculty of Medicine, Udayana University

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Abstract

Dengue is the most important emerging tropical viral disease of humans in the world today. It is estimated that there are between 50 and 100 million cases of dengue fever (DF) and about 500.000 cases of dengue haemorrhagic fever (DHF) each year which require hospitalization. Persons of all ages can be infected and develop dengue fever. However, children younger than 15 years typically present with only a nonspecific self-limited febrile illness. Untreated dengue hemorrhagic fever mostly likely progresses to dengue shock syndrome which is defined as dengue fever with signs of circulatory failure. The prognosis depends on prevention or early recognition and treatment with case fatality rate is as high as 12% to 14% once shock has set in. Management of dengue fever requires rest, oral fluids to compensate for losses via diarrhoea or vomiting, antipyretics and analgesics. Patients who present with shock may require central venous pressure monitoring. An arterial line may be required in unstable patients for the assessment of blood gases, electrolytes, and coagulation profile to help identify patients needing ventilatory support.
THE CORRELATION OF TRANSAMINASES AND LIVER DISEASES Bastianus Alfian Juatmadja; I Wayan Putu Sutirta Yasa; DAP Rasmika dewi; Bagus Komang Satriyasa
Bali Journal of Medical and Health Sciences vol 1no1 2013
Publisher : Faculty of Medicine, Udayana University

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Abstract

The symptoms of liver diseases are very diverging, from the mild one till the severe one. Sometimes we may find that severe heart disorders but the symptoms are too less. We need some tools to make a good diagnosis. We can not only use a good anamnesis, but also have to use good physical examination and the other support test. Transaminase also called aminotransferase. This aminotransferase catalyzes the transfer of the amino group (?NH2) of an amino acid to a carbonyl compound. The liver contains specific transaminases for the transfer of an amino group from glutamic acid to ?-keto acids that correspond to most of the other amino acids. Other transaminases catalyze reactions in which an amino group is transferred from glutamic acid to other compounds. Transamination is one of the principal mechanisms for the formation of necessary amino acids in the metabolism of proteins. Transaminase as a sign to cell damage may divided into Serum Glutamic Oxalocetic Transaminase (SGOT), Serum Glutamic Pyruvic Transaminase (SGPT), and Lactic Dehydrogenase (LDH). Gamma GT and alkali fosfatase correlate with cholestasis. Cholinestrase correlate with liver synthesis capacity.
PENGGUNAAN ANTIBIOTIKA BAGI PENDERITA BALITA PNEUMONIA DAP. Rasmika Dewi; Dewa Ayu Swastini
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol 16, No 3 (2010)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v16i3.1037

Abstract

Pneumonia is a major cause of morbidity and mortality of children under 5 years old (toddlers). The number of antibiotics use as a therapeutic treatment of pneumonia has caused bacterial resistance, medicinal side effect, and increasing medication cost. Thisresearch was carried out intended to know the relationship between antibiotic regimens used for pneumonia therapy and the outcome ofparameters, such as body temperature and respiratory rate (RR), as well as the length of stay. This study is carried out in a retrospectivedescriptive design, using pneumonia patient’s medical record (children under 5 years old), during the period from the 1December 2008. It was shown in this study that the dose of antibiotics given to pneumonia children under 5 years old are in single,combination, and transition form. The single antibiotics most widely used is Cefotaxime (87.5%), and the combination is Ampicillin–Chloramphenicol (94.4%) while transitional is Ampicillin –Chloramphenicol to Cephalosporin group (58.3%). The use of antibiotics forpneumonia among children under five patients either single, combination, and transition was successful in obtaining therapy outcome,including decreasing body temperature from > 38° C to normal body temperature, is 36° C–38° C and decreasing RR value with theaverage length of stay for five (5) days. st January – 31st
SIMVASTATIN GENERIK DAP. Rasmika Dewi; DG. Diah Dharma Santhi; DM Sukrama; AA. Raka Karsana
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol 20, No 2 (2014)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v20i2.1076

Abstract

This study aims to know and determine the lipid profile in patients with hyperlipidemia who consumed Generic Simvastatin comparedwith its patent product contained in the Formularium at Sanglah Hospital. The observations made, were the measurement of the totalcholesterol and low-density lipoprotein (LDL) before and after the drug administration. A total of 30 subjects who met the inclusioncriteria, were divided into two (2) groups, each group consist of 15 persons, the first group was given 20 mg generic Simvastatin(1 tablet daily) for 15 days and Group II given 20 mg patent Simvastatin (1 tablet daily) for 15 day. After 15 days, their blood sampleswere taken and examined for total cholesterol and LDL. Once the data were collected, statistical analysis was done by using the normalitytest, homogeneity and t. Statistical analysis using p-value less than or equal to 0.05 was the limit of significance. The statistical analysisshowed that the data was normally distributed and homogeneous (p≥0.05). The T-test showed that there were significant differencesin the levels of total cholesterol and LDL serum samples before and after the administration of generic simvastatin and patents the(sig.=0.000). However, there was no significant difference in decreased levels of totall cholesterol samples between the generic Simvastatinand patent (sig=0.365 with α=0.05 level). Besides this, there was also no significant difference in the decreased levels of LDL betweengeneric Simvastatin and the patent one (sig=0.372 with α=0.05 level).
Co-Authors AA. Raka Karsana Anak Agung Ngurah Subawa Bagus Komang Satriyasa Bastianus Alfian Juatmadja Desak Gde Diah Dharma Santhi Dewa Ayu Swastini Gede Agus Suwiryawan I Dewa Made Sukrama I Wayan Putu Sutirta Yasa IBN Dwipayana Manuaba Karta Sawenda