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Analisis Dinamika Molekuler Pengaruh Suhu Tubuh Terhadap Keseimbangan Volume Human Serum Albumin (HSA) Menggunakan Model Potensial Lennard-Jones Muhammad Rasyid Sidik; Yanti Yulianti; Dwi Asmi
Jurnal Teori dan Aplikasi Fisika Vol 8, No 2 (2020): Jurnal Teori dan Aplikasi Fisika
Publisher : Universitas Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23960/jtaf.v8i2.2434

Abstract

Research on molecular dynamics analysis of the influence of body temperature on HSA fluid volume balance using the Lennard-Jones potential model with temperature variations of 35 ℃, 37 ℃, and 40 ℃ in the form of cubic systems in GROMACS applications. The results show that the denaturation of HSA that is affected by body temperature causes changes in osmotic pressure in the body with changes in the balance of HSA fluid volume. At temperatures of 35 ℃ denaturations occurs Thr566 to Gln580 with a distance of 20.9 A, Lys444 to Met446 with a distance of 5.76 A, Asn61 to Cys62 with a distance of 3.9 A, Glu570 to Ser579 with a distance of 18.09 A, and Gly431 to Cys438 with a distance of 11.43 A. At a temperature of 37 ℃ denaturations occurs Ile513 to Cys514 has a distance of 3.75 A, Pro303 to Glu311 has a distance of 12.78 A, Asn267 to Ser270 has a distance of 4.65 A, Leu275 to Cys279 has a distance of 7 A At a temperature of 40 ℃ denaturations occurs Ser304 to Glu311 with a distance of 11.38 A, Asn267 to Ile271 with a distance of 7.75 A, Asn61 to Cys62 with a distance of 3.9 A, and Ala511 to Cys514 with a distance of 4.86 A. RMSD results shows that stable structural changes occur in HSA with values of 2.6–9.0 nm. And the Lennard-Jones average energy yield shows that the interaction behavior between HSA atoms is dynamic. At a temperature of 35 ℃ of 7.97E + 05 kJ/mol, a temperature of 37 ℃ of 6.78 kJ/mol, and a temperature of 40 ℃ of 7.89E + 05 kJ/mol.
Pengaruh Waktu Pengeringan Sampel Batubara Tarahan Terhadap Nilai Inherent Moisture Dan Nilai Kalor Batubara wahyuning ramadhanta ardanti; Dwi Asmi; Dahlia Dahlia
Jurnal Fisika Indonesia Vol 24, No 3 (2020)
Publisher : Department of Physics Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jfi.v24i3.57613

Abstract

Telah dilakukan pengujian tentang pengaruh waktu pengeringan sampel batubara tarahan terhadap nilai inherent moisture dan nilai kalor dengan tujuan untuk menentukan pengaruh waktu pengeringan, menentukan selisih nilai inherent moisture dan nilai terhadap waktu pengeringan dan menentukan hubungan antara nilai inherent moisture dan nilai kalor. Sampel batubara yang digunakan dengan kode sampel TRH 412 sampai dengan TRH 416 dan TRH 430 sampai dengan TRH 434. Pengujian yang dilakukan menggunakan standar BS (British Standar). Perbedaan yang diperoleh nilai inherent moisture dan nilai kalor mengahasilkan 7,11 % dan 727 Cal.gr sehingga didapatkan 1% inherent moisture menghasilkan nilai kalor 102,25 Cal/gr. Hasil pengujian nilai inherent moisture dan nilai kalor pada pengeringan 24 jam didapatkan rata-rata sebesar 11,43% dan 6.236,4 Cal/gr. Pada pengujian dengan pengeringan 3 jam didapatkan hasil nilai inherent moisture dan nilai kalor rata-rata sebesar 18,54% dan 5.509,4 Cal/gr. Waktu pengeringan sangat berpengaruh pada nilai inherent moisture dan nilai kalor karena semakin lama pengeringan maka nilai inherent moisture akan turun dan nilai kalor akan naik.
SINTESIS DAN KARAKTERISASI WOLLASTONITE BERBASIS PREKUSOR BIOGENIK SILIKA ABU SEKAM PADI Amilia Rasitiani; Dwi Asmi; Muhammad Badaruddin
Jurnal Teori dan Aplikasi Fisika Vol 11, No 1 (2023): Jurnal Teori dan Aplikasi Fisika
Publisher : Universitas Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23960/jtaf.v11i1.2845

Abstract

The aim of this research is to make wollastonite from silica obtained from rice husk ash and commercial calcium carbonate using the solids reaction method. The DTA-TGA results show mass due to the evaporation of H2O and the decomposition of CaCO3 into CaO along with the calcination temperature, in addition, the DTA results also identify the formation of the β-CaSiO3 phase and the α-CaSiO3 phase. The XRD results of wollastonite obtained were dominated by the β-CaSiO3 phase and the minor phase was α-CaSiO3 this was indicated by the peak intensity of the β-CaSiO3 phase which was higher than the peak intensity of the α-CaSiO3 phase. the second phase in wollastonite is also the result of FTIR results through the analysis of the Si-O-Ca functional group in each wollastonite sample. In addition, the results of the SEM analysis showed the shape of the spheroidal particles (spherical) with an average grain size of 0.19 m, 0.35 m and 0.68 m for the calcination temperatures of 900 oC, 1000 oC and 1100 oC, respectively. The results of this study indicate that the manufacture of wollastonite from the basic ingredients of rice husk silica and commercial calcium carbonate has potential as an alternative material for the manufacture of wollastonite.