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All Journal Majalah Obstetri dan Ginekologi Jurnal Kesehatan Health Notions Health and Medical Journal Oksitosin : Jurnal Ilmiah Kebidanan Biomolecular and Health Science Journal Science Midwifery INDONESIAN MIDWIFERY HEALTH AND SCIENCES JOURNAL Journal Research Midwifery Politeknik Tegal

Budi Prasetyo

Departemen Obsterti Dan Ginekologi, Fakultas Kedokteran Universitas Airlangga, RSUD Dr. Soetomo Surabaya

Author-ID : 2535490

Biochemistry, Genetics & Molecular Biology Dentistry Education Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Veterinary

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FAKTOR RISIKO DUKUNGAN SUAMI TERHADAP KEHAMILAN RISIKO TINGGI Suriari Lestari; Rachmah Indawati; Budi Prasetyo
Jurnal Kesehatan - STIKes Prima Nusantara Vol 12, No 2 (2021): JURNAL KESEHATAN
Publisher : STIKes Prima Nusantara Bukittinggi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35730/jk.v12i2.439

Latar Belakang: WHO memperkirakan sekitar 15-20% ibu hamil yang berada di negara maju atau berkembang mengalami kehamilan risiko tinggi dan/ atau komplikasi. Kehamilan risiko tinggi disebabkan oleh interaksi antara keadaan biologik ibu dengan faktor lingkungan, genetik, dan sosial budaya. Faktor lingkungan berupa dukungan suami menjadi faktor penting dalam masa kehamilan istri.Tujuan: Penelitian ini bertujuan menganalisis pengaruh dukungan sosial suami yang meliputi dukungan emosional, dukungan informasi, dukungan instrumental, dan dukungan penilaian terhadap kehamilan risiko tinggi di wilayah kerja Puskesmas Pringgasela kabupaten Lombok Timur provinsi NTB.Metode: Penelitian ini merupakan Â penelitian analitik observasional dengan rancang bangun case control. Populasi kasus dalam penelitian ini adalah seluruh suami dari ibu hamil risiko tinggi di wilayah kerja Puskesmas Pringgasela. Populasi kontrol adalah seluruh suami dari ibu dengan kehamilan risiko rendah. Perbandingan sampel kasus : sampel kontrol adalah 1 : 1. Dari perhitungan besar sampel minimum diperoleh sampel kasus sebanyak 74 orang dan sampel kontrol sebanyak 74 orang. Data ibu hamil risiko tinggi diperoleh dari register kohort ibu yang tersedia di Poskesdes/ Polindes pada bidan desa. Metode pengambilan sampel secara cluster random sampling. Data primer dikumpulkan menggunakan kuesioner yang telah diuji validitas dan reliabilitasnya. Data skunder diperoleh dari PWS KIA Puskesmas Pringgasela, register kohort ibu, dan buku KIA. Data penelitian dianalisis secara univariate dan multivariate. Analisis multivariate menggunakan uji regresi logistik biner (95% C.I.).Hasil: Hasil analisis multivariate menunjukkan variabel dukungan emosional suami (p=0,006), dukungan informasi suami (p=0,026), dukungan instrumental suami (p=0,020), dan dukungan penilaian suami (p=0,016) merupakan faktor risiko kehamilan risiko tinggi di wilayah kerja Puskesmas Pringgasela.Simpulan: Faktor risiko yang berpengaruh terhadap kehamilan risiko tinggi di wilayah kerja Puskesmas Pringgasela adalah dukungan emosional suami, dukungan informasi suami, dukungan instrumental suami, dan dukungan penghargaan suami.

The Roast Tradition (se'i/nu) and Acute Respiratory Infection in Infants Anita Restu Korbaffo; Budi Prasetyo; Oedojo Soedirham
Health Notions Vol 2, No 3 (2018): March
Publisher : Humanistic Network for Science and Technology (HNST)

The se’i / nu tradition is one tradition that is still maintained by the local community on the island of Timor, where the process of postpartum care of mothers and newborn babies traditionally involves smoking up to 40 days or 3 months using charcoal / embers. (The smoking process involves requiring the new mother and her newborn baby to sit or lay above embers from biomass fuel inside a traditional house). The purpose of this study was to investigate the association of the smoking tradition (se’i / nu) with the incidence of acute respiratory infections in infants at the Eban district health center in North Central Timor. The type of research was analytical. The design used was an observational study. The sampling technique in this study used the total population. The sample size was 42 people. The dependent variable was the incidence of acute respiratory infection, and the independent variable was the smoking tradition (se’I / nu). The results showed that there is a correlation between the smoking tradition (se’i / nu) and the incidence of acute respiratory infection (ARI) in infants at the Eban clinic P = 0.016 (P<α). Keywords: Roast tradition, Acute respiratory infection, Infants

Pengaruh Tingkat Stres dan Kadar Kortisol dengan Jumlah Folikel Dominan pada Penderita Infertilitas yang Menjalani Fertilisasi Invitro Awik Setiyono; Budi Prasetyo; Margarita Maramis
Majalah Obstetri dan Ginekologi Vol. 23 No. 3 (2015): September - Desember 2015
Publisher : Universitas Airlangga

Tujuan: Mempelajari hubungan antara tingkat stres dan kadar kortisol darah dengan jumlah folikel dominan pada pasien infertilitas yang menjalani prosedur fertilisasi in vitroBahan dan Metode: Studi ini merupakan penelitian analitik cross sectionaldi dua klinik infertilitas di Surabaya selama 4 bulan. Didapatkan 30 subyek penelitian yang diambil data mengenai tingkat stres dengan menggunakan 2 kuisioner yaitu Percieved Stres Scale-10 (PSS-10) dan Infertility Reaction Scale (IRS) dan kadar kortisol darah sewaktu pagi. Subyek penelitian kemudian menjalani prosedur stimulasi ovarium dan dilakukan penghitung-an jumlah folikel dominan sebelum dilakukan tindakan ovum pick upHasil: Dengan menggunakan hasil analisa statistik korelasi Spearman didapatkan hasil hubungan negatif antara tingkat stres menggunakan skoring PSS-10 (r=0,64; p<0,01) dan juga IRS (r=0,83; p<0,01) dengan jumlah folikel dominan. Didapatkan pula hubungan negatif antara kadar kortisol darah dengan jumlah folikel dominan (r=0,80 p<0,01).Simpulan: Tingkat stres dapat berdampak pada jumlah folikel dominan. Kadar kortisol yang tinggi dapat menyebabkan jumlah folikel dominan semakin menurun.

Nutritional status of third trimester pregnant women correlates positively with birth weight Ratna Ernawati; Bangun Trapsila Purwaka; Budi Prasetyo
Majalah Obstetri dan Ginekologi Vol. 25 No. 2 (2017): August
Publisher : Universitas Airlangga

Objectives: to identify correlation between nutritional status (energy, macronutrient and fluid intake) of the third trimester pregnant women and birth weight.Materials and Methods: correlative analytic prospective cohort’s study in Public Health Center Jagir, Surabaya with sample comprising healthy pregnant women aged 20-35 years in the third trimester and their newborns (n=34). Respondents noted fluid intake every day for 7 days (record method) and food for 24 hours (recall method). Adequacy of energy intake, macronutrient and fluid (mean) was assessed based on AKG 2012. LBW when <2500 g. Statistical analysis used Pearson correlation's and Spearman's rho with test with significance level of p<0.05.Results: in third trimester pregnant women energy intake (r: 0.854, p: 0.0001) and carbohydrates (r:0.912, p:0.0001) had strong positive correlation, protein intake had moderate positive correlation (r: 0.519, p: 0.0001), fat intake (r: 0.425p: 0.012) and fluid (r: 0.469 p: 0.005) had positive correlation with birth weight. The prevalence of LBW in Public Health Center Jagir Surabaya was 14.7%.Conclusion: Nutritional status of third trimester pregnant women correlates positively with birth weight.

Inadequate fluid intake can increase the risk of constipation among pregnant women Dina Fitriana; Budi Prasetyo; Bangun Trapsila Purwaka
Majalah Obstetri dan Ginekologi Vol. 25 No. 2 (2017): August
Publisher : Universitas Airlangga

Objectives: To analyze the association between the fiber and fluid consumption with constipation in pregnancy.Materials and Methods: An analytic cross-sectional study conducted at Jagir Public Health Center Surabaya, with the samples of healthy pregnant women aged between 20-35 years old (n=99). Respondents were asked to record the amount of daily fluid intake, defecation frequency, and type of faeces, everyday for 7 days, also made a food recall during 24 hours. The recom-mendation of adequate fluid intake in first trimester was 2180 ml/day and 2300 ml/day for second and third trimester. The value of adequate fiber consumption was 25-30 g/day. Constipation diagnosed by the frequency of defecation <2x/week, or based on Bristol Stool Form Scale included as type 1, type 2, or type 3.Results: Pregnant women whose adequate fluid intake was 40,4% and those with adequate fiber intake was 4.1%. The percentage of constipation among them was 29.5%. There was significant association between fluid intake and constipation (p: 0,000; RR:1,85). There was no significant association between fiber intake and constipation p:0,317 (p<0.05). There was also no significant association between parity, gestational age, and level of education with constipation (p<0.05).Conclusion: Inadequate maternal fluid intake can increase the risk of constipation by 1.85 folds, and the adequate fluid intake may prevent constipation during pregnancy.

Comparison of the provision of champedon trunk shell capsule extract and artesunate on placental histopathologic classification in pregnant mice (Mus musculus) malaria model Achmad Yunus; Budi Prasetyo; Erry Gumilar Dachlan; Aty Widyawaruyanti; Widjiati Widjiati
Majalah Obstetri dan Ginekologi Vol. 25 No. 3 (2017): December
Publisher : Universitas Airlangga

Objectives: To compare the effect of chemphedon trunk shell capsule extract with artesunate on placental histopathologic classification in pregnant mice malaria’s models.Materials and Methods: This study was a randomized experi-mental laboratory study in BALBc strains mice with controls. A total of 30 pregnant mice were divided into 3 groups. On day 10 each group was infected with P. berghei. Furthermore, on day 11 each group was subjected to thin blood smear examination and subsequent infection when administered antimalarial positive. Group P1 received Chemphedon trunk shell extract 100 mg/kg BW/day per sonde two times per day for 5 days. Group P2 received 36.4 mg artesunate/kg BW/day for 3 days followed by CMC Na per sonde for 2 days, and group P3 received placebo (CMC Na) for 5 days. On day 16 the mice were dissected on 16 days of pregnancy and the placenta was taken and preparations were made to observe histopathological classification of the placenta according to Rogerson. Grouping was performed accor-ding to placental histopathological classification by Rogerson.Results: Groups receiving cemphedon trunk shell capsule extract, artesunate and placebo revealed p=0.004 (p<0.05), showing that there were two groups with significant difference. To determine which group had significant difference, the test was followed by Mann-Whitney post-hoc test. The results showed chempedon trunk shell capsule group and placebo obtained p=0.007 (p<0.05), indicating significance. Artesunate and placebo groups revealed p=0.003 (p<0.05), also indicating significance. The test results of chemphedon trunk shell capsule extract and artesunate groups showed p=0.475 (p<0.05), indicating no significant differences.Conclusion: Placental histopathologic classification on pregnant mice malaria’s model that received antimalarial chemphedon trunk shell capsule extract of 100 mg/kg BW is better than place-bo and equivalent to artesunate of 36.4mg/kg BW.

Characteristics overview of mother with perinatal death at Dr. Soetomo Hospital in 2015 Yulisa Haslinda; Budi Prasetyo
Majalah Obstetri dan Ginekologi Vol. 24 No. 3 (2016): September - December
Publisher : Universitas Airlangga

Objectives: to determine the frequency distribution of perinatal mortality and maternal characteristic features in terms of age, parity, gestational age and pregnancy complications in Dr.Soetomo Hospital Surabaya in 2015. Materials and Methods: A descriptive study conducted by collecting data on patients who experienced perinatal mortality of infants born from January to December 2015 in Dr. Soetomo, Hospital Surabaya. Samples were collected using total sampling. The samples must meet the following criteria: mothers of infants with perinatal mortality in Dr. Soetomo Hospital, Surabaya, from January to December 2015.Results: There were 206 perinatal deaths out of 1018 births in Dr. Soetomo during 2015, of which 58% was live birth and 42% was stillbirth. Most of perinatal mortality found in the preterm gestational age as much as 78%, and gestational age 28-<37 weeks (58%). Most of perinatal mortality occured in infants with less than 1500 grams birth weight, which was as much as 53% of all perinatal deaths and infant whose birth weight from1500 to 2500 grams was about 29%. Most perinatal mortality found in multigravida (54%) and in infants whose mothers experienced preeclampsia in pregnancy complications (35%), followed by infant mortality in women with non-obstetric complications (23%).Conclusion: Perinatal mortality in Dr. Soetomo Hospital was mostly found in multigravida mothers, 16-35 years old maternal age, 28-37 weeks gestational age and those with complications of preeclampsia.

Sambiloto (AS201-01) is better than standard antimalarial drug (DHP) in reducing Toll-Like Receptor 2 (TLR2) on placenta malaria model Masyitah Hamidah; Aty Widyawaruyanti; Widjiati Widjiati; Budi Prasetyo
Majalah Obstetri dan Ginekologi Vol. 26 No. 2 (2018): August
Publisher : Universitas Airlangga

Objectives: To compare the TLR2 expression in the placenta between treated by sambiloto EA-96 fraction tablet (AS201-01) and dihydroartemisinin-piperaquine phosphate (DHP)Materials and Methods: Experimental study using 24 pregnant mice. All sample divided into 4 groups with randomization are uninfected group, Plasmodium infected group and given placebo, sambiloto (AS201-01) and DHP. Then performed surgery and placental sampling were staining with adopting in tunnel assay method to measure the TLR2 expression of placental.Results: The expression of TLR2 in uninfected group has the lowest rate compared to other groups. The infected and placebo treated group has the highest TLR2 expression campared with sambiloto and DHP. The sambiloto group has not differ signi-ficantly with the group uninfected and lower than DHP.Conclusion: Tablet of sambiloto EA-96 fraction (AS201-01) decreased TLR2 expession better than with DHP tablet.

The effect of sambiloto tablet (AS201-01) on placental Chondroitin Sulfate A (CSA) expression of pregnant mice infected by Plasmodium berghei Nasrul Wahdi; Widjiati Widjiati; Aty Widyawaruyanti; Budi Prasetyo
Majalah Obstetri dan Ginekologi Vol. 26 No. 2 (2018): August
Publisher : Universitas Airlangga

Objectives: To determine the effect of Sambiloto tablet (AS201-01) in reducing the placental Chondroitin Sulfate A (CSA) Expression of pregnant mice infected Plasmodiumberghei.Materials and Methods: Experimental study using 24 pregnant mice were divided into 4 groups with randomization. Uninfected group, the placebo group, the Sambiloto tablet (AS201-01) group and the DHP tablet (as a standart drug) group. The last three groups, were infected with P. bergheion day 9th of pregnancy, and the treatment was started at day 11th of pregnancy, and samples were terminated at day 15th of pregnancy by surgery. Placental sampling were stained with Tunnel assay to measure placental CSA antibodies.Results: The placental Chondroitin Sulfate A (CSA) expression. Uninfected group compared to Sambiloto tablet (AS201-01) groups was not significantly different (p>0.05), uninfected group compared with the other treatment groups differ meaningfully (p<0.05). Placebo group compared with all groups significantly different (p<0.05). Sambiloto tablet (AS201-01) group compared to uninfected group (p>0.05) was not significantly different, with another group was significantly different (p<0.05). DHP tablet group compared to all the groups was significantly different (p<0.05).Conclusion: Placental Chondroitin Sulfate A (CSA)expression of mice infected by Plasmodium berghei treated with Sambiloto tablet (AS201-01) lower than DHP tablet.

Comparison of the effect of sambiloto (AS 201-01) tablet and dihydroartemisinin-piperaquine on macrophage MIF expression in mice placenta infected with Plasmodium berghei Desak Ketut Ayu Aryani; Budi Prasetyo; Aty Widyawaruyanti; Widjiati Widjiati
Majalah Obstetri dan Ginekologi Vol. 26 No. 3 (2018): December
Publisher : Universitas Airlangga

Objective: To compare the administration of sambiloto tablets (AS201-01) and dihydroartemisinin-piperaquine phosphate tablets in pregnant mice infected by P. berghei on the expression of MIF in the placenta.Materials and Methods: Experimental laboratory research, 24 pregnant mice were divided into 4 groups with randomization, ie. non-infected, placebo, sambiloto (AS201-01) and DHP groups. On day 9 P. berghei was infected, on day 11 the treatment was given, day 15 the surgery was performed, placental samples were taken, immunohistochemical staining was given, and MIF expression was assessed.Results: The expression of MIF in the group not infected with P. berghei had the lowest mean, while the highest mean was found in the placebo group. Uninfected groups were not significantly different from sambiloto (AS201-01) tablet group. Sambiloto tablet group (AS201-01) had lower MIF expression than DHP group, but it was not significantly different. Sambiloto tablet group (AS201-01) showed lower MIF expression than placebo. MIF expression in DHP group was lower than that in placebo group. From the lowest, the MIF expressions were as follows: group not infected with P. berghei, group receiving sambiloto (AS201-01) tablet, DHP group and placebo group.Conclusion: MIF expression in the placenta of pregnant mice infected with P. berghei and receiving sambiloto (AS20-01) tablets was not different from those receiving DHP tablets.

Co-Authors Achmad Yunus Ahmad Hadi Modi Anita Dewi Anggraini Anita Restu Korbaffo Ardi Eko Marsanto Aty Widyawaruyanti Awik Setiyono Bangun Trapsila Purwaka Bangun Trapsila Purwaka Daniel Yoseph Pardomuan Desak Ketut Ayu Aryani Dian Hosiana Pangaribuan Dian Nirmala Aprilia Dina Fitriana Erry Gumilar Dachlan Faizah, Zakiyatul Hari Paraton Izzati Dwi Kuntaman Kuntaman Laili Muninggar Linda Dewanti M Yusuf Maemonah, Maemonah Maramis, Margarita M. Masyitah Hamidah Mokhamad Anhar Dani Muhammad Yusuf Nasrul Wahdi Oedojo Soedirham Rachmah Indawati Ratna Ernawati Rizki Pranadyan Rizki Pranadyan Roy Prasojo Wibowo Salsabila Salsabila Sulistiawati Sulistiawati Suriari Lestari Visky Afrina Widati Fatmaningrum Widjiati Widjiati Widjiati Widjiati Yulisa Haslinda

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