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Widati Fatmaningrum
Departement of Public Health-Preventive Medicine, Faculty of Medicine, Airlangga University

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Effect of Probiotic Milk containing L. casei Shirota on Immunoglobulin G Levels among Anemic Adolescent Girls Elya Sugianti; Annis Catur Adi; Ikeu Ekayanti; Trias Mahmudiono; Widati Fatmaningrum; Siti Nur Husnul Yusmiati
Health Notions Vol 2, No 2 (2018): February
Publisher : Humanistic Network for Science and Technology (HNST)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (195.919 KB) | DOI: 10.33846/hn.v2i2.138

Abstract

Probiotic play important role on immune systems. This study was to investigate effect of probiotic milk containing L. casei Shirota on immunoglobulin G levels among anemic adolescent girls. A total of 22 adolescent girls aged 13-18 years with anemia were included on this study. The subjects were separated into 2 groups i.e. a probiotic group and a control group by simple random sampling. During 4 weeks, a probiotic group received 1 tablet of 60 Fe elemental + 250 µg folate acid once a week and probiotic milk once daily. While a control group received 1 tablet of 60 Fe elemental + 250 µg folate acid once a week. Blood samples were collected at 0 and 4 weeks and assayed for immunoglobulin G levels by ELISA. Immunoglobulin G levels were not significantly increase after intervention. Compared with control group, probiotic milk administration in probiotic group did not significantly increased immunoglobulin G levels (p>0.05). The probiotic milk containing L. casei Shirota did not improve immunoglobulin G levels on anemic adolescent girls. Keywords: Probiotic, Immunoglobulin G levels, Anemia, Adolescent girls