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All Journal Journal of Tropical Life Science : International Journal of Theoretical, Experimental, and Applied Life Sciences METAMORFOSA Journal of Biological Sciences Jurnal Ilmu Perairan (Aquatic Science) Jurnal Farmasi Andalas Jurnal Sains dan Teknologi Farmasi Jurnal Riset Kimia Indonesian Journal of Pharmaceutical Science and Technology INDONESIAN JOURNAL OF PHARMACY Jurnal Penelitian Pendidikan IPA (JPPIPA) JURNAL EDUCATION AND DEVELOPMENT JSFK (Jurnal Sains Farmasi & Klinis) JFIOnline Majalah Kedokteran Andalas Jurnal Farmasi Higea JURNAL PENELITIAN FARMASI & HERBAL Journal of Pharmaceutical and Health Research REACTOR : Journal of Research On Chemistry And Engineering

Akmal Djamaan

Universitas Andalas

Author-ID : 254739

Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Earth & Planetary Sciences Education Energy Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Medicine & Pharmacology Nursing Physics Public Health

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Isolation of Secondary Metabolite A. niger “In-Habiting” Queen M. gilvus Hagen.’s Nest Yohannes Alen; Atika Melati; Gemmy Sarina; Akmal Djamaan
Indonesian Journal of Pharmaceutical Science and Technology Vol 5, No 2 (2018)
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Aspergillus niger is pathogen fungi that can live in various locations and can live contiguous with many hosts, one of them is queen termite’s nest. The aims of the study were to isolated the secondary metabilite of A.niger. Extraction proccess of secondary metabolite compounds was carried out by maceration method using methanol solvent. Based on that proccess, methanol extract was be yield 4,32% sample weight. Fractination proccess was carried out in the separating funnel using ethyl acetate solvent, which ethyl acetate fraction was be yield 14.39% methanol extract. Separation of the compounds was carried out by column chromatography method using n-hexane and ethyl asetate eluents. Purification of the compounds were done by recrystallization method using n-hexane and ethyl asetate. Two secondary metabolite compounds were successfully isolated from ethyl acetate fraction of the methanolic extract of fungus A. niger “In-Habiting” queen termite’s nest M. gilvus Hagen. Based on organoleptic examination, the compound signed AM-12-22-01 is 35 mg, white needle crystals, melting point 151-153 oC. While, the AM-12-60-01* is 15 mg, white needle crystals, melting point 91-93 oC. Based on the chemical analysis, thin layer chromatography, ultraviolet and infrared spectra data it was identified that AM-12-22-01 and AM-12-60-01 were a phenolic compounds.Key words: isolation, A. niger, In-Habiting, M. gilvus Hagen.

Potensi Jamur Endofit pada Tumbuhan Mangrove Avicennia marina di Kuala Enok Indragiri Hilir sebagai Penghasil Antibiotika Kustiasih Lestari; Anthoni Agustien; Akmal Djamaan
Metamorfosa: Journal of Biological Sciences Vol 6 No 1 (2019)
Publisher : Prodi Magister Ilmu Biologi, Fakultas MIPA, Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/metamorfosa.2019.v06.i01.p13

This study provides an overview of the potential of endophytic fungi isolated from leaves, stems, mangrove roots A. marina as a producer of antibiotics tested for Staphylococcus aureus, Escherichia coli, Candida albicans. This research was carried out in the microbiology laboratory of the Health Polytechnic of the Ministry of Health of Riau from March to June 2017. This study used a laboratory experimental method, the data presented in descriptive form. The stages of the study were: identification of A. marina plants, fungal isolation, qualitative tests of flavonoids isolates from endophytic fungal, and antibacterial activity test. The results showed that from 15 isolates of endophytic fungi, 5 isolates producing antibiotics. FAA 3 isolate showed the highest antibiotic activity with 24 mm the diameter of the inhibitory zone, while the lowest inhibition zone was FAA 4 isolate by forming a diameter of inhibitory zone of 7 mm and the results of qualitative tests of metabolites showed as secondary flvonoid metabolites. This research can be used as a source of information for the community in utilizing mangrove plants as an alternative in improving health.

Isolasi Dan Identifikasi Mikroba Penghasil Antibiotika Dari Sampel Lumpur Sungai Kampar Riau Musyirna Rahmah Nst; Akmal Djamaan; Gustina '
Ilmu Perairan (Aquatic Science) Vol 8, No 2 (2010)
Publisher : Universitas Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31258/jipas.8.2.p.1-11

Isolation of microbes that produce antibiotic found in the sludge of Kamparriver has been carrie out using crowded plate method. The sludge were inoculated inPDA and NA, and incubated for 24 hours. Microbes showing clear zone wereobserved, this indicated the microbes produce antibiotics. The microbes wereisolated and identified. The result showed there were three species Bacillus sp ofwhich potencial to produce antibiotic compund.Key words: microbe, isolation,antibiotic

PRODUCTION AND CHARACTERIZATION OF A BIODEGRADABLE POLYMER POLY(3-HYDROXYBUTYRIC ACID) FROM GLUCOSE USING Erwinia sp. USMI-20 Akmal Djamaan; Mohamed Isa Abd. Majid; Mohd. Azizan Mohd. Noor
Indonesian Journal of Pharmacy Vol 12 No 4, 2001
Publisher : Faculty of Pharmacy Universitas Gadjah Mada, Yogyakarta, Skip Utara, 55281, Indonesia

The production and characterization of a biodegradable polymer poly(3-hydroxybutyric acid), P(3HB) from glucose as sole carbon source by Erwinia sp. USMI-20 has been carried out. Results showed that Erwinia sp. USMI-20 could produced P(3HB) with a maximum polymer content of 48 % of the dry cell weight, an amount of polymer of 2.8 g/l, a dry cell weight of 5.8 g/l, a maximum specific growth rate of 0.21 h-1. a maximum polymer production rate of 0.02/h, yield YP(3HB)//C of 0.21 g/g, with the optimum fermentation time of 48 hours. The melting temperature (T) and glass transition temperature (Tg) of the P(3HB) were 175 ˚C and 15 ˚C, respectively. The weigh-average molecular weight (Mw) was in the range of 1,000,000 to 1,120,000 D whereas the number-average molecular weight (Mn) was in the range of 420,000 to 580,000 D with the polydispersity index (Mw,Mn) in range of 1.9 to 2.4. Key word: biodegradable polymer, glucose and Erwina sp.

Penggunaan Biopolimer Polikaprolakton Sebagai Matrik Herbisida Lepas Lambat Asam 2,4-Diklorofenoksi Asetat Akmal Djamaan; Maria Ulfa; Netty Suharti
Jurnal Farmasi Higea Vol 4, No 2 (2012)
Publisher : STIFARM Padang

The formulation of microcapsule of 2,4-dichlorophenoxy acetate acid using biopolymer polycaprolactone as a matrix using solvent evaporation method has been carried out. The microcapsule formula was used three types with the ratio 2:1, 1:1, 1:2 between 2,4-dichlorophenoxy acetate acid and polycaprolactone. Distribution particle test was used calibrated microscope. Active substance release test was detected by UV-Vis spectrophotometer. Polycaprolactone can be used as the matrix polymer for slow release preparations and influence to the release of active substance 2,4-dichlorophenoxyacetate acid. Result showed that recovery test of the formula-2 containing 86.5 % higher than formula-1, 84.5% and formula-3 78.2%. Model of the kinetics of the release active substance from microcapsule which correlation coefficient close to one is formula-1 which follow zero order kinetics.

Produksi Bioplastik Poli (3-Hidroksibutirat) (P(3HB)) Secara Proses Fermentasi Menggunakan Bakteri Bacillus brevis FAAC-20801 Dari Minyak Kelapa Sawit Sebagai Sumber Karbon Krisyanella Krisyanella; Mimi Susanti; Akmal Djamaan
Jurnal Farmasi Higea Vol 2, No 1 (2010)
Publisher : STIFARM Padang

The production of bioplastic P(3HB) with fermentation process by Bacillus brevis FAAC-20801 from palm oil as carbon has been carried out. The fermentation process was conducted throug at pH 7, 37oC and agitation rate of 200 rpm for 60 hours. The characterization of the bioplastic production was based on cell growth, P(3HB) content and P(3HB) percentage. Results showed that the optimum time was 48 hours, with fermentation biomassa 277 mg, P(3HB) content of 7.2 mg/ 20 mg biomassa (36 % b/b). Fermentation process in bioreactor produced P(3HB) higher than in rotary shaker incubator.

Optimasi Proses Produksi Bioplastik Poli (3-Hidroksibutirat) Dengan Bakteri Bacillus sp FAAC 20801 Menggunakan Bahan Dasar Jerami Padi Setelah Fermentasi Akmal Djamaan; Witra Aulia; Krisyanella Krisyanella
Jurnal Farmasi Higea Vol 3, No 2 (2011)
Publisher : STIFARM Padang

The optimation of production process of bioplastic poly (3 - hidroxybutirat) (P(3HB) fermentation by Bacillus sp FAAC 20801 bacteria, using straw as carbon source has been carried out. Detection of P(3HB) produced using gas chromatography. The highest glucosa level obtain by using H2SO4 5% for hidrolisis. From 46800 mg straw (glucosa concentration 200 mg/mL) produce 5379 mg biomassa and 0.058 mg P(3HB) ; from 83400 mg straw (glucosa concentration 400 mg/mL) produce 5011 mg biomassa and 0.124 mg P(3HB) ; from 142800 mg straw (glucosa concentration 600 mg/mL) produce 3992 mg biomassa and 2.309 mg P(3HB).

Pemanfaatan Jerami Sisa Produk Pertanian sebagai Bahan Dasar Produksi Etanol Secara Fermentasi (Optimasi Produksi Berdasarkan Perbedaan Konsentrasi Inokulum dan Lama Fermentasi) Akmal Djamaan; Mahrani Napitupulu; Krisyanella Krisyanella
Jurnal Farmasi Higea Vol 1, No 2 (2009)
Publisher : STIFARM Padang

Research about exploiting of straw as component of ethanol as fermentation based on difference able of inoculums consentration and fermentation time has been studied. Straw utilized in this research is result of agriculture raffle from rice plant type IR 46, which taken away from rice field the district of Lubuk Minturun, Padang. The first, stage hydrolysis was done to straw using H2SO4 P 1% with various time 30, 60, 120, 180 and 240 minute and determined glucose produced for each sample. The fermentation of ethanol by using Saccharomyces cereviceae bacterium were conducted at temperature 30ºC with speed 100 rpm. Sampling was taking every 6 hours (6, 12, 18, 24, 30, 36, 42, 48, 54, 60, 66). The inoculum’s grade level is variation by 1, 2, 3% v/v. Results showed that the optimum hydrolysis time wich mark by highest glucose rate is minute 240 with grade level 0.7765 %. The highest ethanol grade of which can be yielded with inoculum 1% was 0.02066 % v/v at yeast inoculum 2 % was of 0.02549 % v/v and yeast inoculum 3 % was of 0. 07804 % v/v.

Isolasi Mikroba Endofit Dari Kulit Batang, Daun, dan Kulit Buah Manggis (Garcinia mangostana L.) Pengkulturan Serta Uji Aktivitas Antimikrobanya Akmal Djamaan; Asia Asia; Rina Wahyuni
Jurnal Farmasi Higea Vol 6, No 1 (2014)
Publisher : STIFARM Padang

The antimicrobial activity of endophytes microbe that symbiosis with mangosteen had been carried out. There were 12 fungal’s isolates and 14 bacterial’s isolates had been isolated from cortex, lief, and pericarp of Garcinia mangostana L. Each fungal’s isolates were fermented in Soybean Extract Broth liquid medium for 1 week at on a rotary shaker incubator at a 25-270 C and 90 rpm speed. Each bacterial’s isolates were fermented in water corn soaked medium for 24 hours on a rotary shaker incubator at 300C and 120 rpm speed. Fermented fungal’s and bacterial’s were tested their antimicrobial’s activity against Staphylococcus aureus, Escherichia coli and Candida albicans with agar diffusion methode. The result showed that J-G1 (Candida sp) and J-T1 (Candida sp) were fungal’s isolates that ware active against Escherichia coli with inhibition diameter 10 mm. J-H1 (Curvularis sp), J-G2 (Candida sp), J-T1 (Candida sp) were fungal’s isolates that were active against Staphylococcus aureus with inhibition diameter 9 mm, 11 mm and 13 mm respectively. B-T2 (Klebsiella sp)and B-K51 (Bacillus sp1) were bacterial’s isolates that were active againts Escherichia coli with inhibition diameter 13 mm and 18 mm respectively. B-H (Bacillus sp2), B-G (Bacillus sp2), B-P1 (Bacillus sp1), B-K101(Bacillus sp1) and B-K102 (Bacillus sp1) were bacterial’s isolates that were active againts Staphylococcus aureus with inhibition diameter 11 mm, 14 mm, 15 mm, 16 mm and 15 mm respectively.

Pemanfaatan Ekstrak Etanol Daun Murbai (Morus alba L.) Sebagai Bahan Aktif Pasta Gigi Dan Uji Aktivitas Anti Bakteri Terhadap Plak Gigi Akmal Djamaan; Fatimah Saidah; Rina Wahyuni
Jurnal Farmasi Higea Vol 6, No 2 (2014)
Publisher : STIFARM Padang

The formulation of leaf´s murbey ethanol extract´s toothpaste and its activities against dental plaque´s bacteries had been done. Pre test showed the leaf´s murbey ethanol extracts at 4% of concentration gave an optimal diameter of inhibition against dental plague. Based that fact, this research would have made 3 formulas at toothpaste from leaf´s murbey extract at 1%, 2%, and 4% of concentration. All of formulas would have wade with the same base of toothpaste. All of formulas would be characterized of pharmaceutic´s properties and antibacteria´s activities, that would be compared with toothpaste “S” and “P” as a standard. The result shawed all formulas gave a good characteristic of pharmaceutic properties. F3 had gave a good diameter of inhibition, that was 21.875 mm, where as the “S” and “P” of toothpaste had gave a diameter of inhibition respectively 23.875 mm and 22.75mm. There was a significant difference of inhibition´s diameter of all formulas at 0.05 level of confidence.

Co-Authors Agusri Boestari Andani Eka Putra Anthoni Agustien Arfiandi Arfiandi Asia Asia Asiska Permata Dewi Asiska Permata Dewi Asiska Permatadewi Atika Melati Bakhtra, Dwi Dinni Aulia Bilqis Nurganiyu Densi Selpia Sopianti Densi Selpia Sopianti Desma Yuni Dewi Gulyla Hari Dian Handayani Dini Hanifa Edtyva Monicha Elmi Sariani Hasibuan Erizal Zaini Fatimah Saidah Gustina ' Inayati Rahmi irfan mustafa Irfan Mustafa Krisyanella Krisyanella Krisyanella Krisyanella Kustiasih Lestari Laura Syahrul Lola Alviche Mahrani Napitupulu Majid, Mohammed Isa Abdul Maria Ulfa Marlina . Melati, Atika Melzi Octaviani Mimi Susanti Mohamed Isa Abd. Majid Mohd. Azizan Mohd. Noor Muslim Suardi Musyirna Rahmah Nst Netty Suharti Netty Suharty Noor, Mohd. Azizan Mohd. Novesar Jamarun Refilda Refilda Rendowaty, Agnes Rezki Amelia Rezki Amelia Rina Wahyuni Rini Agustin Rusmana Wijaya Setia Ningrat Rustini Rustini Rustini Rustini Salman - Salman - Sarina, Gemmy Sri Elfina Syamsuardi Syamsuardi Syukri Arief Syukria Ikhsan Zam Syukria Ikhsan Zam Witra Aulia Witra Aulia Yohannes Alen Yufri Aldi Yutra Noka

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