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Tingkat Kejadian Rabies Dan Pemetaan Status Desa Tertular di Kecamatan Mengwi, Badung, Bali Tahun 2015 Putri, Raden Roro Chandra Gita Soetarmono; Kardena, I Made; Gunata, I Ketut
Indonesia Medicus Veterinus Vol 6 (2) 2017
Publisher : Faculty of Veterinary Medicine, Udayana University

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Abstract

Penelitian ini bertujuan untuk mengetahui tingkat kejadian rabies dan titik koordinat kejadian rabies di Kecamatan Mengwi periode 2015. Tingkat insiden rabies dianalisis secara deskriptif kuantitatif dengan menggunakan program Microsoft Excel dan untuk keperluan pemetaan kasus digunakan software Quantum-GIS. Dalam penelitian ini digunakan 2 jenis data yaitu data primer yang didapatkan dengan cara menentukan titik koordinat dimana ditemukannya lokasi kasus positif rabies pada anjing yang telah terkonfirmasi rabies di laboratorium dan data sekunder berupa data kasus anjing rabies dan jumlah populasi anjing di Kecamatan Mengwi Kabupaten Badung. Tingkat kejadian rabies di Kecamatan Mengwi periode Januari hingga Agustus 2015 sebesar 0,17%. Dari 20 desa yang ada di Kecamatan Mengwi enam desa di antaranya ditemukan kejadian rabies, yaitu pada April 2015 ditemukan di koordinat 115o 16’ 85” BT dan 8o 54’ 58” LS yang berada di Desa Mengwi, pada Mei 2015 ditemukan di titik 115o 16’ 15” BT dan 8o 56’ 71” LS yang berada di Desa Mengwitani, pada Juli 2015 ditemukan di tiga titik berbeda yaitu di koordinat 115o 17’ 66” BT dan 8o 57’ 78” LS yang berada di Desa Kapal, 115o 17’ 50” BT dan 8o 59’ 26” LS yang berada di Desa Abianbase, koordinat 115o 12’ 46” BT dan 8o 62’ 25” LS yang berada di Desa Munggu, sedangkan pada Agustus 2015 kejadian rabies ditemukan di dua titik yang berbeda yaitu di koordinat 115o 15’ BT dan 8o 59’ LS yang berada di Desa Abianbase, koordinat kedua ditemukan di 115o 17’ 75” BT dan 8o 52’ 30” LS yang berada di Desa Werdi Bhuwana.
Perancangan dan Pembuatan Sistem Informasi Gudang (Studi Kasus : PT. PLN (Persero) Area Surabaya Barat) Budi Prasetyo; Timothy John Pattiasina; Anggya Nanda Soetarmono
Teknika Vol 4 No 1 (2015): November 2015
Publisher : Pusat Penelitian dan Pengabdian Kepada Masyarakat, Institut Informatika Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34148/teknika.v4i1.30

Abstract

Sistem informasi berbasis komputerisasi merupakan salah satu faktor penting bagi perusahaan - perusahaan dalam mengelola segala aktifitas perusahaan. Bahkan penggunaan teknologi komputer tersebut akan menjadi syarat utama untuk menunjukkan kualitas suatu bidang dan menjadi modal terpenting dalam memenangkan persaingan. Sistem Informasi Gudang di PT. PLN (Persero) Area Surabaya Utara dibangun karena masih menggunakan cara manual untuk melakukan penerimaan barang datang, permintaan barang, dan pemberian barang, sehingga mempengaruhi dalam pelaksanaan operasional kerja, baik dalam segi kecepatan, pelayanan, dari segi informasi yang dihasilkan. Untuk itu diperlukan suatu sistem yang dapat memudahkan manajemen dalam mengelola seluruh aktifitas yang ada di gudang. Sistem Informasi Gudang PT.PLN (Persero) Area Surabaya Utara adalah suatu sistem yang mengelola data barang, data rayon, dan transaksi yang ada di gudang. Sistem ini menggambarkan rangkaian kegiatan dari mulai mengelola barang datang, permintaan barang, barang keluar hingga pelaporannya. Setelah melalui tahapan analisis dan implementasi, kemudian dilakukan tahapan selanjutnya yaitu tahap pengujian sistem dimana pengujian ini menggunakan metode pengujian white box yang berfokus pada pengujian perangkat lunak. Dari hasil pengujian, dapat ditarik kesimpulan bahwa Sistem Informasi Gudang di PT.PLN (Pesero) Area Surabaya dibangun untuk mempermudah manajemen dalam melakukan pengawasan dan pengendalian di gudang.
TOTAL CHOLESTEROL AND C-REACTIVE PROTEIN LEVELS AS A PROGNOSTIC MARKERS OF UROSEPSIS wahyudi, septa surya; Hardjowijoto, Sunaryo; Soebadi, Doddy M; Soetojo, Soetojo; Djojodimedjo, Tarmono; Budiono, Budiono
Indonesian Journal of Urology Vol 23 No 1 (2016)
Publisher : Indonesian Urological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32421/juri.v23i1.198

Abstract

Objective: To investigate whether total cholesterol and C-reactive protein levels could be use as a prognostic factor for outcome in patients with urosepsis. Material & Methods: An analytic observational study using 30 patients assigned for total cholesterol and CRP level at the day of admission, three days later, and on the last day of sepsis or on the dead day. All subjects were managed according to standard urosepsis therapy. At the 14th day of treatment, patients were evaluated with a clinical severity score. Then we classified the outcome as improve/good condition, worse, and died. The variables were statistically tested using Spearman’s rho test with software SPSS 20. P < 0.05 was consider significant. Result: From 30 subjects with urosepsis, we found 15 patients in septic condition, 14 patients had severe sepsis and one patient had septic shock. The mean of total cholesterol level in patient with died and worse was lower than that in patient with good outcome. Day-1 (63.25 mg/dl and 101.38 mg/dl vs 119.5 mg/dl), day-3 (56.0 mg/dl and 93.6 mg/dl vs 128.6 mg/dl) and last day/died day (51.0 mg/dl and 82.25 mg/dl vs 154.8 mg/dl). The mean of CRP level in patient with died and worse was higher than that in patient with good outcome. Day-1 (177.18 mg/l and 146.74 mg/l vs 88.1 mg/l), day 3 (127.1 mg/l and 148.8 mg/l vs 56.2 mg/l) and last day/died day (141.88 mg/l and 88.71 mg/l vs 31.58 mg/l). These were statistically significant between total cholesterol and CRP levels in determining the outcome of urosepsis patient. Day-1 (p 0.000 vs 0.011), day-3 (p 0.000 vs 0.002), and last day/died day (p 0.000 vs 0.000). The coefficient correlation total cholesterol was better than CRP in day-1 (rho -0.633 vs 0.459), day-3 (rho -0.755 vs 0.543), and last day/died day (rho -0.874 vs 0.686). Conclusion: Low total cholesterol and high C-reactive protein levels can be used as poor prognostic in urosepsis patients. Total cholesterol level was better than CRP as a prognostic marker.
DIURETIC DOPPLER ULTRASOUND FOR EVALUATING OBSTRUCTED AND NON-OBSTRUCTED KIDNEY Fajrial, Ahmad Fajrial; Soebadi, Doddy M; Djojodimedjo, Tarmono; S, Muhammad Yamin; Pudjirahardjo, Widodo
Indonesian Journal of Urology Vol 20 No 2 (2013)
Publisher : Indonesian Urological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32421/juri.v20i2.11

Abstract

Objective: The objective of this study was to evaluate the implementation of diuretic Doppler Ultrasound (DDU) to differentiate the obstructed and non-obstructed kidney. Material & Method: From 28 patients, we gathered data of 48 kidneys in accordance with the inclusion criteria. We evaluated the Doppler Ultrasound Resistive Index (RI) before and after administration of diuretic, using the renogram as the comparison. The result of renogram was categorized into total obstruction (n = 19), partial obstruction (n = 18), and non-obstructive dilatation (n = 3). The statistical analysis was performed using Anova test followed by Tukey HSD test. We also performed diagnostic test, the total and partial obstruction were categorized within obstructed group (n = 37) whereas normal and non-obstructed dilated kidney categorized as non-obstructed group (n = 11). Results: Average change of RI (ΔRI) was 0,542 ± 0,0457 for total obstruction, 0,0428 ± 0,0439 for partial obstruction, 0,0275 ± 0,0392 for normal kidney, -0,0300 ± 0,0361 for non obstructed dilated kidney. The result of normality and homogeneity test indicated the data were normally distributed. One-way Anova test revealed significant differences of ΔRI between groups. The subsequent Tukey HSD test indicated that there were significant differences in total and partial obstruction groups, compared to non-obstructive dilated kidney group. Based on ΔRI cut-off point (0,035) the diagnostic characteristics were 88,5% sensitivity and 72,3% specificity. Conclusion: RI of Diuretic Doppler Ultrasound is a valuable examination to evaluate obstructed and non-obstructed kidney. The cut-off point of 0,035 indicated probability of obstructive kidney. Keywords: Resistive index, renogram, obstructive kidney, non-obstructive kidney. 
DIFFERENCES OF TESTOSTERONE LEVELS TO THE DURATION OF INHALED NICOTINE EXPOSURE IN SPRAGUE-DAWLEY MALE WHITE RATS Ramadhan, Ido Putra; Djojodimedjo, Tarmono; Soebadi, Doddy M
Indonesian Journal of Urology Vol 27 No 1 (2020)
Publisher : Indonesian Urological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32421/juri.v27i1.593

Abstract

Objective: To analyze the differences in testosterone level in young Sprague-Dawley white rats after exposure of inhaled nicotine and the recovery effect that occurs when nicotine exposure is stopped. Material & Methods: This is an experimental study, which variable measurements were taken after the experimental animals were treated. The experimental grouping process was carried out randomly, with repetitions of 12 experimental animals in each group and the control group as a comparison (negative control). This study using male Sprague-Dawley white rats as samples. Nicotine administration was carried out by inhalation using pure nicotine (C10H14N2), which was diluted using distilled water. Treatment group 1 (P1) was given nicotine exposure for 30 days, treatment group 2 (P2) for 15 days, and treatment group 3 (P3) for 15 days and then stopped for 15 days compared to the control group. Testosterone levels are measured using the ELISA (Enzyme-Linked Immunosorbent Assay) method in the morning. Results: The lowest testosterone levels were found in the P1 and significantly different from the P2 (p=0.029) and P3 (p=0.001). The results of the analysis show that a decrease in testosterone levels in mice is related to the duration of nicotine exposure. Conclusion: Testosterone levels in the control group were significantly higher compared to the treatment group that exposed by nicotine inhalation with a dose of 4 mg/kgBW/day for 15 days, and also there is a significant recovery effect on testosterone levels after the treatment was halted for 15 days.
EFFECT OF VITAMIN E (α-TOCOPHEROL) ADMINISTRATION ON SPERM MOTILITY AND MORPHOLOGY OF SPRAGUE DAWLEY STRAIN RATS AFTER CISPLATIN TREATMENT Aditya, Dimas Visa; Djojodimedjo, Tarmono; Soebadi, Doddy M
Indonesian Journal of Urology Vol 26 No 1 (2019)
Publisher : Indonesian Urological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32421/juri.v26i1.539

Abstract

Objective: To evaluate the protective effects of vitamin E α-tocopherol isomer against the toxicity of cisplatin on sperm motility and morphology in Sprague Dawley rats. Material & Methods: Twenty-four rats were grouped into four groups (n=6). The control group (CN) was injected with normal saline, second group (CP) was injected with cisplatin, the third group (P1) was injected with cisplatin and vitamin E 50 mg/kgBW for 7 weeks P.O, the fourth group (P2) was injected with cisplatin and vitamin E 200 mg/kgBW for 7 weeks P.O. Vitamin E was given from 3 weeks before cisplatin injection and 4 weeks following cisplatin injection. At 7th week, all the samples were undergoing bilateral orchidectomy. Vitamin E that being used in this study was α-tocopherol isomer. Results: Cisplatin decreased motility and morphology of spermatozoa significantly against controls. Vitamin E 50 mg/kgBW and 200 mg/kgBW significantly increased motility of spermatozoa (p<0.05) compared to those in the cisplatin group only. Vitamin E 50 mg/kgBW, and 200 mg/kgBW did not have a significant difference in spermatozoa motility compare to control groups. Vitamin E 50 mg/kgBW and 200 mg/kgBW could increase the spermatozoa morphology significantly compare to those cisplatin only group. Vitamin E 50 mg/kgBW, and 200 mg/kgBW did not have a significant difference in spermatozoa morphology compared to control groups. Conclusion: α-tocopherol 50 mg/kgBW and 200 mg/kgBW provided a same protective effect against spermatozoa damage especially in motility and morphology aspect due to cisplatin exposure. Therefore, in this study it was more recommended to use α-tocopherol in 50 mg/kgBW dose than 200 mg/kgBW.
PROFILE OF PATIENTS WITH URINARY TRACT STONE AT UROLOGY DEPARTMENT OF SOETOMO GENERAL HOSPITAL SURABAYA IN JANUARY 2016-DECEMBER 2016 Kurniawan, Reza; Djojodimedjo, Tarmono; Rahayu, Anny Setijo
Indonesian Journal of Urology Vol 27 No 1 (2020)
Publisher : Indonesian Urological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32421/juri.v27i1.506

Abstract

Objective: To identify the profile of patients with urinary tract stones at the Urology Department of Soetomo General Hospital Surabaya in January 2016-December 2016. Material & methods: This was descriptive retrospective research conducted at the Urology Department of Soetomo General Hospital Surabaya. The data were obtained from medical records of patients diagnosed with urinary tract stone, with the amount of data collected was 62. The variables included were age, gender, address, main complaint, type and location of urinary tract stone. Results: The ratio of male:female among patients with urinary tract stone is 33:29. Most of the patients with urinary tract stone were aged 46-60 years old (52%), came with the main complaint of flank pain (79%), had the uric acid type of urinary tract stone (48%), and had urinary tract stone located at the kidneys (65%). Conclusion: Profile of patients with urinary tract stone at the Urology Department of Soetomo General Hospital Surabaya is as following: Ratio of male:female among patients with urinary tract stone is 33:29. Most of the patients with urinary tract stone were aged 46-60 years old, came with the main complaint of flank pain, had the uric acid type of urinary tract stone, and had urinary tract stone located at the kidneys.
THE EFFECTIVENESS OF TAMSULOSIN, SOLIFENACIN, AND COMBINATIONS THERAPY TAMSULOSIN ADDED SOLIFENACIN ON LOWER URINARY TRACT SYMPTOMS AFTER DOUBLE J STENT INSERTION Pramana, Ida Bagus Putra; Rizaldi, Fikri; Djojodimedjo, Tarmono
Indonesian Journal of Urology Vol 26 No 2 (2019)
Publisher : Indonesian Urological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32421/juri.v26i2.503

Abstract

Objective: Insertion of DJ Stent is a procedure that is often done by urologist. Insertion of DJ Stent can cause LUTS complaints and greatly affect the physical and psychosocial health of patients. The aim of this study was to determine the effectiveness difference of tamsulosin therapy 0.4 mg/day, solifenacin 5 mg/day and the combination of tamsulosin therapy 0.4 mg/day added solifenacin 5 mg/day to manage LUTS complaint after DJ Stent insertion. Material & Methods: This study was a randomized placebo-controlled trial. There were 4 groups, group I received placebo, group II received tamsulosin 0.4 mg/day, group III received solifenacin 5 mg/day, and group IV received combination therapy of tamsulosin 0.4 mg/day added solifenacin 5 mg/day. Evaluation based on International Prostatic Symptom Score (IPSS) and Ureteral Stent Symptom Questioner (USSQ) score. Data were analyzed using SPSS 21.0. It is said to be significant if p<0.05. Results: There were a total of 32 samples consist of 19 (59.3%) men and 13 (40.6%) women. There were significant improvements in the score of total IPSS, IPSS storage and IPSS quality of life score in patients who received combination therapy (p<0.05) when compared with patients who received monotherapy. The highest decrease in USSQ scores 1, 2, 3, 4, 5 and 6 were in the group that received combination therapy when compared with the monotherapy group. Conclusion: The combination therapy is safe and effective to improve IPSS total, IPSS storage and IPSS Quality of Life scores compared with monotherapy.
THE EFFECT OF DEXAMETHASONE ON SPERMATOGONIUM AND SERTOLI CELL OF IPSILATERAL TESTIS IN UNILATERAL TESTICULAR TORSION WISTAR RAT Efendi, Ferdyan Rachmat; Renaldo, Johan; Djojodimedjo, Tarmono
Indonesian Journal of Urology Vol 25 No 2 (2018)
Publisher : Indonesian Urological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32421/juri.v25i2.466

Abstract

Objective: To investigate the effect of dexamethasone on spermatogonium and sertoli cell of ipsilateral testis in unilateral testicular torsion strain wistar rat. Material & Method: Experimental study with post-test only control group design. The present  study was conducted on 30 Wistar male rats aged 10 – 12 weeks grouped into 5 groups. Group I was the normal/sham operation group (KN), group II was left testicular torsion for 4 hours group and followed  by manual detorsion  (K1), group III was left testicular torsion for 10 hours group and followed  by manual detorsion (K2),  group IV was left testicular torsion for 4 hours group and given dexamethasone 10 mg/kg body weight subcutaneously 30 minutes before manual etorsion (D1), and group V was left testicular torsion for 10 hours group and  given dexamethasone 10 mg/kg body weight subcutaneously 30 minutes before manual detorsion. All rats had left orchidectomy 4 hours after detorsion. The number of spermatogonium and sertoli cells were counted in histological seminiferous tubular testis that have obtained Haematoxylin Eosin staining. Data were analyzed by ANNOVA followed by Post Hoc Tukey for spermatogonium and Kruskal Wallis followed by Mann Whitney test for sertoli cell. Differences were considered significant at p <0.05. Results: There was significant difference in the mean number of spermatogonium between K1 & D1 group. Otherwise, there was no significant difference in the mean number of spermatogonium between K2 & D2. There was significant difference in the mean number of Sertoli cells between K1 & D1 group, likewise that between K2 & D2 group. Conclusion: These results suggest that dexamethasone has protective effect in spermatogonium and sertoli cell in testicular torsion for 4 hours.
PRESEPSIN AND PROCALCITONIN VALUES TO DETERMINE THE PROGNOSIS OF UROSEPSIS Addin, Sofyan Rais; Djojodimedjo, Tarmono; Rizaldi, Fikri
Indonesian Journal of Urology Vol 25 No 2 (2018)
Publisher : Indonesian Urological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32421/juri.v25i2.463

Abstract

Objective: To evaluate the prognostic value of presepsin and procalcitonin in patient with urosepsis. Material & Method: This is an observational prospective study. Patients who fulfilled the criteria for urosepsis at Soetomo Hospital Surabaya were enrolled. Presepsin and procalcitonin were measured at first admission. All patients were managed according to standard urosepsis therapy. At the 28th day of treatment, patients were evaluated and classified into survivor and non-survivor. The statistical analysis were tested with logistic regression test using software SPSS 23. Results: 30 urosepsis patients were included in this study with average age was 48.3 years (range 21-77 years). There were 23 survivor and 7 non-survivor. Mean presepsin values were higher in non-survivor than in survivor but the difference was not significant (4405 ± 4664 vs 4042 ± 2643, p=0.259). Mean procalcitonin value was significantly higher in non-survivor than in survivor (7.68 ± 6.81 vs 3.27 ± 2.74, p=0.013). Using the cut off value ≥2.24 ng/ml, procalcitonin can predict mortality in 28 days with sensitivity 71.4% and specificity 47.8%. Conclusion: Presepsin can not be used to determine the prognosis of urosepsis patients. Procalcitonin showed a significant correlation with outcome of urosepsis patients so it can be use to determine the prognosis of urosepsis.