Clara Meliyanti Kusharto
Departemen Gizi Masyarakat FEMA IPB

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PENGARUH PEMBERIAN BUBUK EKSTRAK CU-TURUNAN KLOROFIL DAUN CINCAU (Premna oblongijolia Merr.) TERHADAP PROFIL LIPID DARAH KELINCI Nurdin Nurdin; Ali Khomsan; Sri Anna Marliyati; Faisal Anwar; Clara Meliyanti Kusharto; Dewi Ratih Agungpriyono
Media Gizi dan Keluarga Vol. 32 No. 1 (2008): Media Gizi dan Keluarga
Publisher : Media Gizi dan Keluarga

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ABSTRACT. The aim of this research was to produce cincau copper-derivative chlorophyll powder and to observe its phYSico-chemical properties and the effect on blood lipid profile of5 month male New Zealand White rabbits. The blood lipid profile observed were total cholesterol, triglyceride, HDL (high-denSity lipoprotein) cholesterol, and LDL (low-density lipoprotein) cholesterol. A two months treatment was conducted A randomblock design was applied with the following treatment on each experimental unit: PO (basal diet, negative control), PI (basal diet with cholesterol 0.1% (wlw) added, positive control), P2 (basal diet with cholesterol 0.1% (wlw) and 16.7 mglkg-body weight/d natural chlorophyll powder added), P3 (basal diet with cholesterol 0.1% (wlw) and 16.7 mglkgbody weight/d copper-derivative of chlorophyll powder added), P4 (basal diet withcholesterol 0.1% (wlw) and 50.1 mglkg-body weightld copper-derivative of chlorophyll powder added}, P5 (basal diet with cholesterol 0.1% (wlw), and 16.7 mglkg-body weight/dcommercial chlorophyll powder added The results of study showed that cincau leaves chlorophyll extract solution with Cu1+ 100 mglL level produce the cincau copper-derivate chlorophyll powder with highest pH, solubility, and greenness compared to other copper levels. Feeding with copper-derivative of chlorophyll cincau powder (P3) most likely decreased total cholesterol, triglycerides, LDL cholesterol increased the HDL cholesterol,and decreased atherosclerosis risk after 2 month as compare to feeding contain of natural chlorophyll (P2). Keywords: Premna oblongifolia Merr., copper-derivate chlorophyll powder, totalcholesterol, triglyceride. HDL cholesterol, LDL cholesterol
PENGARUH SUPLEMEN IODIUM DAN BETA KAROTEN TERHADAP STATUS IODIUM DAN STATUS GIZI IBU HAMIL DI DAERAH ENDEMIK GAKI Astuti Lamid; Rimbawan Rimbawan; Ali Khomsan; Clara Meliyanti Kusharto; Muhilal Muhilal
Media Gizi dan Keluarga Vol. 31 No. 2 (2007): Media Gizi dan Keluarga
Publisher : Media Gizi dan Keluarga

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ABSTRACT. Iodine Deficiency Disorders (IDD) prevalence ofpregnant women is 16% and this would have consequence of risk during delivery and  nutritional status of the children. The aims ofthis study was to measure the effect ofiodized oil and beta carotene on the nutritional, iodine and thyroid stimulating hormone (TSH) status of pregnant women and to determine nutrition, iodine and cyanide intakes from food consumed by pregnant women. Research design ofthe study was quasi experiment. Pregnant women on the first trimester were chosen and divided into three groups. The first group was given iodized oil at 200mg iodine, the second group was treated with iodized oil at 30mg iodine every month for 6 months, and the third group was given as group 2 plus beta-carotene at 30mg each month for six months. Data collected were nutrients, iodine, and cyanide intake from food consumed and the parameter measured were serum TSH, urine iodine excretion (UIE), body weight and upper arm circumference. Chi Square, ANOVA and Kruskall Wallis were applied for statistical analysis. Iodine consumed by pregnant women was closed to the recommended daily allowance (RDA). iodized oil supplement could increase the UIE for 2 times at trimester 3 ofthe pregnancy. Furthermore, the treatment could redure the TSH value during pregnancy. The supplement could supply iodine during pregnancy. Keywords: iodine, hipothyroid, beta caroten, nutritional status