Article Per Year (5 Year)
p-Index From 2018 - 2023
3.817
P-Index
This Author published in this journals
All Journal Qanun Medika - Medical Journal Faculty of Medicine Muhammadiyah Surabaya Jurnal Keperawatan Jurnal Surya Masyarakat Jurnal Kesehatan Islam : Islamic Health Journal Medical Technology and Public Health Journal Medical and Health Science Journal Community Development Journal Biomolecular and Health Science Journal Abdimas: Jurnal Pengabdian Masyarakat Universitas Merdeka Malang REMIK : Riset dan E-Jurnal Manajemen Informatika Komputer Jurnal Surya Masyarakat Darmabakti : Junal Pengabdian dan Pemberdayaan Masyarakat International Islamic Medical Journal
Salim, Hotimah Masdan
Universitas Nahdlatul Ulama Surabaya
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Computer Science & IT Decision Sciences, Operations Research & Management Education Engineering Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

Published : 24 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 24 Documents
Search

 1   2   3 
Efek Saffron (Crocus Sativus) Terhadap TNF-Α Pada Model Artritis Reumatoid Karina Dwiyanti; Hotimah Masdan Salim
Jurnal Kesehatan Islam : Islamic Health Journal Vol 9, No 1 (2020): Jurnal Kesehatan Islam : Islamic Health Journal
Publisher : Publikasi oleh Fakultas Kedokteran Universitas Islam Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33474/jki.v9i1.8867

Abstract

Artritis Reumatoid (AR) merupakan penyakit autoimun yang mempengaruhi sendi yang dapat menyebabkan kerusakan sendi yang progresif dan deformitas. Pada penyakit peradangan kronis ini terdapat banyak sitokin inflamasi yang salah satunya adalah TNF-α yang merupakan sitokin utama yang berlimpah dalam sinovium yang sedang meradang. Saffron dikenal karena sifat antioksidannya yang kuat dan sifat anti peradangan. Kemampuan pengambilan radikal pada saffron berhubungan dengan kemampuannya sebagai anti inflamasi yang dapat memblokir produksi sitokin pro-inflamasi seperti TNF-α. Penelitian ini bertujuan untuk merangkum peran saffron (Crocus sativus) dan konstituennya terhadap TNF-α pada model artritis reumatoid. Pencarian literatur dilakukan dengan menggunakan database PubMed Central dengan hasil screening didapatkan empat jurnal yang memenuhi kriteria inklusi. Pada hasil analisis telaah jurnal pada penelitian ini didapatkan bahwa literatur ilmiah mengkonfirmasi peran saffron (Crocus sativus) dalam menurunkan kadar TNF-α pada model artritis reumatoid.
PEMERIKSAAN FISIK KESEHATAN DAN PEMERIKSAAN GULA DARAH ACAK PADA MASYARAKAT DISEKITAR PONPES AL-HIDAYAH NGAWI, JAWA TIMUR Salim, Hotimah Masdan; dr, Marselli Widya Lestari
JURNAL PENGEMBANGAN KOMUNITAS Vol 2 No 1 (2018): August
Publisher : JURNAL PENGEMBANGAN KOMUNITAS

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (270.436 KB)

Abstract

Masyarakat sekitar pondok pesantren Al-Hidayah secara umum adalah petani karena PP Al-Hidayah terletak di daerah lereng gunung Lawu daerah kecamatan Kendal. Masalah kesehatan pada masyarakat setempat sering dialami, mengingat lokasi geografis yang dekat dengan lerenggunung. Pelaksanaan kegiatan pengabdian kepada masyarakat ini berdasarkan atas permintaandari ponpes AL-Hidayah untuk menjaga kesehatan warga sekitar ponpe. Solusi untuk menanganimasalah tersebut adalah melaksanakan pemeriksaan fisik, dan pengobatan gratis melalui programpengabdian kepada masyarakat. Target nya adalah masayarkat di dan sekitar ponpes Al-Hidayah,Ngawi. Luaran dari kegiatan ini adalah meningkatkan kesadaran dan pengetahuan masyarakatdalam upaya menjaga kesehatannya. Kapasitas pelayanan kegiatan pengabdian kepadamasyarakat kami batasi untuk 150 peserta yang di distribusikan secara merata di wilayah ponpesAl-Hidayah. Pada pemeriksaan didapatkan peserta laki-laki 24 dan wanita 54 peserta. Dari hasilpemeriksaan gula darah acak didapatkan 3 orang yang memiliki GDA tinggi dan 18 orang belumpasti. Kesimpulan dari pelaksanaan kegiatan pengmas ini secara umum berjalan dengan lancar.Diharapkan kegiatan ini dapat meningkatkan kesadaran masyarakat tentang kesehatan dalamupaya meningat derajat kesahatan secara optimal.
The Effects of High-fat Diet on Histological Changes of Kidneys in Rats Hotimah Masdan Salim; Lintan Farizqi Kurnia; Tri Wahyu Bintarti; Handayani Handayani
Biomolecular and Health Science Journal Vol. 1 No. 2 (2018): Biomolecular and Health Science Journal
Publisher : Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (305.929 KB) | DOI: 10.20473/bhsj.v1i2.9675

Abstract

Introduction Hypercholesterolemia contributes as a risk factor for endothelial dysfunction in the kidneys and worsens the condition of patients with previous kidney damage. This study aimed to examine the effect of hypercholesterol diet in kidney structure.Methods: This was an experimental study, a case control using eight-week-old Rattus novergicus, divided into control and treatment group. High-fat diet (HFD) was administrated orally to treatment group for 14 days. All data statistically analyzed with two-paired ANOVA and post hoc for comparison.Results: Histological analysis using hematoxylin-eosin staining showed degeneration in nephrons, including glomerulosclerosis, segmental necrosis and tubular defects. The mononuclear cell infiltration was Increased in HFD group significantly (P<0.05).Conclusion: We concluded that a high fat diet induced obesity and may lead to renal deformities as a result of histopathological changes such as dilatation, tubular defects, inflammation and connective tissue enlargement of the kidney.
PEMERIKSAAN FISIK KESEHATAN DAN PEMERIKSAAN GULA DARAH ACAK PADA MASYARAKAT DISEKITAR PONPES AL-HIDAYAH NGAWI, JAWA TIMUR Hotimah Masdan Salim; Marselli Widya Lestari dr
Community Development Journal Vol 2 No 1 (2018): Community Development Journal
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (270.436 KB) | DOI: 10.33086/cdj.v2i1.705

Abstract

Masyarakat sekitar pondok pesantren Al-Hidayah secara umum adalah petani karena PP Al-Hidayah terletak di daerah lereng gunung Lawu daerah kecamatan Kendal. Masalah kesehatan pada masyarakat setempat sering dialami, mengingat lokasi geografis yang dekat dengan lerenggunung. Pelaksanaan kegiatan pengabdian kepada masyarakat ini berdasarkan atas permintaandari ponpes AL-Hidayah untuk menjaga kesehatan warga sekitar ponpe. Solusi untuk menanganimasalah tersebut adalah melaksanakan pemeriksaan fisik, dan pengobatan gratis melalui programpengabdian kepada masyarakat. Target nya adalah masayarkat di dan sekitar ponpes Al-Hidayah,Ngawi. Luaran dari kegiatan ini adalah meningkatkan kesadaran dan pengetahuan masyarakatdalam upaya menjaga kesehatannya. Kapasitas pelayanan kegiatan pengabdian kepadamasyarakat kami batasi untuk 150 peserta yang di distribusikan secara merata di wilayah ponpesAl-Hidayah. Pada pemeriksaan didapatkan peserta laki-laki 24 dan wanita 54 peserta. Dari hasilpemeriksaan gula darah acak didapatkan 3 orang yang memiliki GDA tinggi dan 18 orang belumpasti. Kesimpulan dari pelaksanaan kegiatan pengmas ini secara umum berjalan dengan lancar.Diharapkan kegiatan ini dapat meningkatkan kesadaran masyarakat tentang kesehatan dalamupaya meningat derajat kesahatan secara optimal.
REVIEW ARTICLE: AMEBIASIS MOLECULAR PATHOGENESIS DEVELOPMENT Muliani, Nurlina; Salim, Hotimah Masdan
Jurnal Ilmu Kesehatan dan Kesehatan Vol 3 No 2 (2019): AUGUST
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mhsj.v3i2.1195

Abstract

Amebiasis is one of the gastrointestinal tract infection disease caused by Entamoeba histolytica ,a parasitic protozoan. Amebiasis is the second disease, caused by parasite, that leading cause of death after malaria. Infection occurs through faecal-oral route and after ingestion a contaminated food and beverages by human faeces. The pathogenesis of E. histolytica can be classified into 3 processes, i.e: death of host cell, inflammation, and parasitic invasion. The recent years, a molecularly amebiasis pathogenesis has been developed, i.e: adherence, phagocytosis, tropogocytosis of host cell and how the parasites can survive and attack host cells so it can cause an infection in humans. Molecular development is an important thing to be considered in the selection of amebiasis therapy.
Dengue Vaccine Development at the Dengue virus serotypes Adinda Desi Irawati; Hotimah Masdan Salim
Jurnal Medis Islam Internasional Vol 1 No 1 (2019): December
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/iimj.v1i1.1360

Abstract

Dengue hemorrhagic fever (DHF) is a disease caused by dengue virus (DENV1-4) and is transmitted by the Aedes aegypti mosquito. However, in 2015, official data from the member countries, WHO reported more than 3.2 million cases, including 10,200 severe dengue cases and 1181 deaths. The protein encoded by the genome of dengue virus. Major structural and non structural proteins making up the genome of dengue. From genomic data several studies found that mechanism of vaccine that can use in dengue virus. Several vaccines was establish in the world for example Live attenuated Vaccine, Chimera Vaccine, Subunit Vaccine, DNA vaccines DENV, Activated DENV Vaccine - Whole Virus Particles, Activated DENV Vaccine - Recombinant Subunit DENV, and DENV Vaccine 5.
Pencegahan Penyakit Diabetes Mellitus melalui Pelatihan Pembuatan Jamu Saintifik bagi Warga Kecamatan Wonokromo Surabaya Devyana Dyah Wulandari; Hotimah Masdan Salim; Andreas Putro Ragil Santoso; Endah Budi Permana Putri
Jurnal Surya Masyarakat Vol 4, No 1 (2021): November 2021
Publisher : Universitas Muhammadiyah Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26714/jsm.4.1.2021.104-111

Abstract

Diabetes mellitus is a chronic disease caused by the pancreas not being able to produce enough insulin so that glucose levels in the blood cannot be controlled. Symptoms of this disease are characterized by polyuria, polydipsia, polyphagia and elevated blood glucose levels. Diabetes mellitus is a non-communicable disease that ranks 7th in the world's cause of death and Indonesia is a country with diabetes which is ranked 4th in the world. Prevention and treatment of diabetes mellitus patients can be done through various efforts, one of which is traditional herbal medicine. Therefore, the community development team held a training event for preparation scientific herbs in the context of preventing diabetes mellitus for residents of Wonokromo Surabaya. The results showed that there was an increase in public understanding about the dangers of diabetes mellitus with an increase in the average value from 45% to 90% and an increase in skills in preparation scientific herbal medicine from 40% to 95%. So it can be concluded that this activity brings very good benefits for the residents of Wonokromo Surabaya.
Hypoglycemic Effects of Extract Nigella Sativa in Diabetic mice model Evi Awwaliya; Hotimah Masdan Salim; David Sajid Muhammad; Deny Febriwijaya Romadhani; Nadia Nisaussholihah
Jurnal Medis Islam Internasional Vol 1 No 1 (2019): December
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/iimj.v1i1.1327

Abstract

Background; Adiponectin is an important adipokine with anti-inflammatory and insulin-sensitizing effects, the circulating levels of which are reduced in individuals with type 2 diabetes and obesity. Indeed, there is evidence that adiponectin released from perivascular adipose tissue (PVAT), that may play a key role in vascular physiology, as bioactive molecules released from it could have direct paracrine effects on the underlying vessel. The present study investigated the effects of extract Nigella sativa (N. sativa) on blood glucose levels of diabetic mice. Materials; Eight-week-old male musmusculus were treated with alloxan (150 mg/ kg) by a single intraperitoneal injection to induce diabetes mellitus. At 3 days of injection, N. sativa extract (150 and 300 mg/kg) was administered via gavage for 2 weeks. Results: The extract of N.Sativa administration significantly reduced blood glucose level (P < 0.05). However, N.Sativa did not alter a body weight Conclusion: Extract of Nigella Sativa improved blood glucose level in diabetic mice model.
Comparison The Value Of Bta Sputum Between Pulmonary Tuberculosis Patients With Diabetes Mellitus And Pulmonary Tuberculosis Patients Non-Diabetes Mellitus. Bagas Setiawan Ihsan Zaini; Adyan Donastin; Lea Maera Shanty; Hotimah Masdan Salim
Jurnal Kesehatan Islam : Islamic Health Journal Vol 9, No 2 (2020): Jurnal Kesehatan Islam : Islamic Health Journal
Publisher : Publikasi oleh Fakultas Kedokteran Universitas Islam Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33474/jki.v9i2.8869

Abstract

Background & Aims: Tuberculosis (TB) is a health problem. Based on the WHO report in 2016, Indonesia is a developing country with the second largest TB case. One risk factor for pulmonary tuberculosis is having a history of diabetes mellitus disease. The aim of this research is to examine the differences the value of BTA sputum between pulmonary TB patients with diabetes mellitus and pulmonary TB patients non-diabetes mellitus.Methods: This research is descriptive analytic with comparative study. This study uses secondary data in Islamic Jemursari Surabaya Hospital period January - December 2017. The results will be processed using descriptive analysis and Mann-Whitney test with SPSS 25.00 for windows.Results: This research obtained 68 samples consisting of 34 the pulmonary TB non-diabetes mellitus and 34 pulmonary TB with diabetes mellitus. In pulmonary TB patients non-diabetes mellitus most have negative BTA sputum values, while pulmonary TB with diabetes mellitus is positive (+1), so there are differences in the value of BTA sputum with a significance value 0.001 (<0.05).Conclusion: There is a difference in the value of BTA sputum between pulmonary TB patients with diabetes mellitus and pulmonary TB patients non-diabetes mellitus. It caused in patients with diabetes mellitus have immunological abnormalities, especially IFN-γ and pulmonary physiological disorder.
Upaya Meningkatkan Sistem Kekebalan Tubuh Anak Usia Sekolah di Masa Pandemi COVID-19 Salim, Hotimah Masdan; Bintarti, Tri Wahyuni; Fitriyah, Fifi Khoirul; Alam, Ilham Putra; Muhammada, Davida Sajid; Nisaussholihah, Nadia
Abdimas: Jurnal Pengabdian Masyarakat Universitas Merdeka Malang Vol 6, No 2 (2021): May 2021
Publisher : University of Merdeka Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26905/abdimas.v6i2.5001

Abstract

COVID-19 is a SARS virus infection that has spread throughout the world including in Indonesia. The existence of this pandemic has a significant impact on all countries, such as health, economy, education, and all supporting sectors of a country. In Indonesia itself adapting the New Normal to deal with this global pandemic. New Normal is associated with new habit changes that also impact the health level of children. So, the purpose of community service (PKM) is to provide education as an effort to increase the child's immune system in the face of the COVID-19 pandemic. This PKM is implemented at the Baca Rumah Kita Foundation in the Mejoyo Tenggilis sub-district. This PKM is carried out by presenting counseling to school-age children with interactive methods and games as well as health checks as screening and providing supplements to improve the child's immune system. Based on the PKM results, it was found that the children were enthusiastic about this activity. From the results of health screening, participants aged 5-10 years were 84.21%. With a nutritional status of 47.37% less, 15.79% less nutrition, 26.32% good nutrition, and 10.53% over nutrition. Based on the results of this screening, it can be used as a measure that the growth and development of children in this region needs special attention, especially during the current pandemic.DOI: https://doi.org/10.26905/abdimas.v6i2.5001
Co-Authors Achmad Hilman Fahmy Adinda Desi Irawati Aditya Bhayusakti Adyan Donastin Ainul Rofik Alam, Ilham Putra Algristian, Hafid Andi Roesbiantoro Andreas Putro Ragil Santoso Ardianti, Ami Bagas Setiawan Ihsan Zaini Bagas Setiawan Ihsan Zaini Bintarti, Tri Wahyuni Bintarti, Tri Wahyuni Choirotussanijah Choirotussanijah David Sajid Muhammad Dayu Satriya Wibawa Deny Febriwijaya Romadhani Deny Febriwijaya Romadhani Devyana Dyah Wulandari dr, Marselli Widya Lestari Dwimantoro Edza Aria Wikurendra Endah Budi Permana Putri Evi Awwaliya Evi Octavia Djamaludin Evy Silvia Awwaliyah Fifi Khoirul Fitriyah Handayani Handayani Ilham Putera Alam Ilham Putra Alam Ima Kurniastuti, Ima Iswahyudi Iswahyudi Izki Masyaqqoni Pujiana Karina Dwiyanti Lea Maera Shanty Lintan Farizqi Kurnia Lysa Veterini Maria Ulfa Marinda Dwi Puspitarini Marselli Widya Lestari dr Michio Shimabukuro Muhammada, Davida Sajid Muliani, Nurlina Nadia Nisaussholihah Nahdatien, Ima Nisaussholihah, Nadia Nur Azizah AS Nurlina Muliani R.A. Hani Faradis Reza Mahendra Syafiuddin, Achmad Tri Deviasari Wulan Tri Wahyu Bintarti Widya Dio Kharisma Yuani Setiwati