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All Journal Jurnal Veteriner Indonesian Journal of Tropical and Infectious Disease Jurnal Layanan Masyarakat (Journal of Public Service) Journal of Parasite Science Ovozoa: Journal of Animal Reproduction Indian Journal of Forensic Medicine & Toxicology journal of Basic Medical Veterinary
Emy Koestanti Sabdoningrum
Faculty Of Veterinary Medicine, Universitas Airlangga, Surabaya, Indonesia
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Decision Sciences, Operations Research & Management Earth & Planetary Sciences Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Public Health Social Sciences Veterinary Other

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In Silico Study : Phyllanthus Niruri L as Immunomodulator Against Covid-19 Mohammad Sukmanadi1 , Emy Koestanti Sabdoningrum2 aditya Tri Ananda3
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i4.12095

Abstract

In December 2019, a mysterious case of pneumonia was first reported in Wuhan, Hubei Province. Thesource of transmission of this case is still unknown, but the first case was linked to the fish market in Wuhan.From 18 December to 29 December 2019, there were five patients treated with Acute Respiratory DistressSyndrome (ARDS). 2 From 31 December 2019 to 3 January 2020 this case increased rapidly, marked by 44cases reported. In less than a month, the disease has spread to other provinces in China, Thailand, Japan andSouth Korea. This virus can be transmitted from human to human and has spread widely in China and morethan 190 other countries and territories. On 12 March 2020, WHO announced COVID-19 as a pandemic.As of March 29, 2020, there were 634,835 cases and 33,106 deaths worldwide. While in Indonesia, 1,528cases were confirmed with COVID-19 and 136 deaths. Phyllanthus niruri L (meniran) is one type ofimmunostimulator that can improve the immune system in animal experiments and humans. This studyaims to determine Phyllanthus niruri L as an immunomodulator for Covid-19. From the results of researchconducted that Phyllanthus niruri L can improve the activities and functions of several non-specific immunesystem components and specific immune systems, both soluble and cell-related forms. The conclusion fromthe results of this study is Phyllanthus niruri L as an immunomodulator for Covid-19.
Novel Combination of Andrographis paniculata and Phyllanthus niruri to Improve Performance of Laying Hens Infected with Escherichia coli Sri Hidanah1 , Emy Koestanti Sabdoningrum1,2, Sri Chusniati3 , M. Bagus Kurniawan Saputra4
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 1 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i1.13637

Abstract

The study aims to learn the efficacy combination of Phyllanthus niruri and Androgaphis paniculata toimprove the performance of laying hens infected with Escherichia coli pathogen. Fifty laying hens of IsaBrown strain were randomly divided into 5 treatments, each treatment was divided into 10 replications(n=10). Treatment P0- (control group without infected), P0+ (hens group infected with Avian Pathogenic’sEscherichia coli without given extract), P1 (hens group infected with Avian Pathogenic’s Escherichia coliwith 10% Phyllanthus niruri extract and 30% Androgaphis paniculata), P2 (hens group infected with AvianPathogenic’s Escherichia coli with 20% Phyllanthus niruri extract and 20% Androgaphis paniculata) andP3 (hens group infected with Avian Pathogenic’s Escherichia coli with 30% Phyllanthus niruri extract and10% Androgaphis paniculata). Performances observed were feed consumption, Hen Day Production, eggsweight and feed conversion. Data analyzed by ANOVA and tested with the F test. The feed consumptionshowed in P1 was different from P3, P2, P0+ and P0-, P1 was different from P2 but not with P3, P0+, andP0- showed significantly different in each treatment. In P3 showed no differences with all treatments. Theeggs weight showed different in P0+ for all treatments, while the other treatments in P1, P2, P3 and P0-showed no differences. The feed conversion showed in P0+ was different for all treatments, while othertreatments showed no difference. P0+ treatment compared to (P0-, P1, P2) was significantly different, P0+treatment compared to P3 treatment was not significantly different, between P3 and P1 treatment was notsignificantly different, and between P1 and P2 with P0- was not significantly different, also between P3 withP2 and P0- treatments was significantly different. Supply of P. niruri extract. and A. paniculata in layinghens can improve the performance of laying hens infected with Escherichia coli pathogen.
Peningkatan Respons Imun Non Spesifik Ikan Gurame Pascapemberian Ekstrak Air Panas Mikroalga Spirulina platensis (ENHANCEMENT OF NON-SPECIFIC IMMUNE RESPONSE OF OSPHRONEMUS GOURAMY AFTER GIVING OF HOT WATER EXTRACT SPIRULINA PLATENSIS) Woro Hastuti Satyantini; Agustono Agustono; Emy Koestanti Sabdoningrum; Myrna Budi; Lina Wafia Asmi
Jurnal Veteriner Vol 17 No 3 (2016)
Publisher : Faculty of Veterinary Medicine, Udayana University and Published in collaboration with the Indonesia Veterinarian Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (136.344 KB)

Abstract

Hot water extract of Spirulina platensis which is contain of lipopolysaccharide can be used as animmunostimulant. This study aimed to determine the effect of hot water extract of S. platensis throughinjection on the non-specific immune response of Osphronemusgouramy. The treatment was given throughintraperitoneal injection of hot water extract of S. platensis with doses of 1%, 10%, 20% and PBS, PhosphateBuffer Saline (control) 0.1 ml/fish. Fish reared in the aquarium (67 l volune) with density 12 fishes/aquarium with average weight of 7.5 – 8.5 g/fish. Blood samples of fish taken from the caudal vein on day0 (before administration of the extract), 3 and 5 days after administration of the extract for the measurementof total leucocytes, differential leucocytes and phagocytic activity. Results showed an increased in totalleucocytes, phagocytic activity, monocytes and neutrophils of fish that given hot water extract of S. platensis.The addition of hot water extract of S. platensis at 1% through injection gave total leucocytes, phagocyticactivity, monocytes and neutrophils on days 3 were 543.73 x 103sel/mm3,69.30%, 34.33% and 14%respectively higher and significantly different to control.
New Biotype of Vibrio cholerae O1 from Clinical Isolates in Surabaya Garry Cores de Vries; Emy Koestanti Sabdoningrum; Dadik Rahardjo
Indonesian Journal of Tropical and Infectious Disease Vol. 1 No. 1 (2010)
Publisher : Institute of Topical Disease Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (646.647 KB) | DOI: 10.20473/ijtid.v1i1.3724

Abstract

A surveillance of new pathogenic variants of Vibrio cholerae O1 strains was initiated to identify the emerge and spread throughout Surabaya. Findings from seven years (1994–2000) and from years 2008 until now by using a two-fold surveillance strategy was pursued involving 1) hospital-based case recognition, and 2) environment samples. Rectal swabs and environment samples were transported to ITD-UNAIR, Surabaya for culture and isolates were characterized by serotypic identification and arbitrarily primed PCR fingerprints revealed a group of strains with similar fingerprint patterns that are distinct from those of the current El Tor epidemic strain. These strains have been analyzed by in vitro technique and the group has been denominated the Surabaya-Indonesian variant of V. cholerae O1.
EFFECTIVENESS OF MENIRAN (PHYLLANTHUS NIRURI LINN) AS ANTIBACTERIAL FOR RESISTANCE ANTIBIOTICS PREVENTION OF ENTEROTOXIN ESCHERICHIA COLI Sri Hidanah; Emy Koestanti Sabdoningrum; Retno Sri Wahyuni; Arini Rahmi Dewi; Erma - Safitri
Indonesian Journal of Tropical and Infectious Disease Vol. 7 No. 2 (2018)
Publisher : Institute of Topical Disease Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (338.153 KB) | DOI: 10.20473/ijtid.v7i2.7328

Abstract

Escherichia coli (E. coli) can be isolated from the environment both inside and outside the hospes body. There were 89 serotypes in which showed 21% resistance to various antibiotics, such as enterotoxigenic E.coli. Alternative efforts are needed to overcome this, one of them through the use of medicinal plants, such as meniran (Phyllanthus niruri Linn). Meniran plant is an immunomodulator that serves to repair the immune system of the body. The aim of research is the research was done through several stages: isolation and identification of enterotoxigenic E. coli from several broiler farms in East Java using the polymerase chain reaction (PCR) method, E. coli resistance test against some antibiotics, making meniran extract and activation test against enterotoxigenic E. coli n The study was divided into five treatments: T0+ (group of chickens were infected by enterotoxigenic E. coli T0- (control group, not infected), T1 (infected by enteroxigenic E. coli + 20% meniran extract), T2 (infected by enterotoxigenic E. coli + 25% extract meniran), T3 (infected by enterotoxigenic E. coli + 30% extract meniran). Data were analyzed by ANOVA (Analysis of Variance). The results show that all of E. coli DNA isolates which tested by the PCR method show positive reactions at 600 bp. The next stage, the enterotoxigenic E. coli are resistant to some antibiotics, such as amoxicillin, ampicillin, erythromycin, cephalosporins, tetracycline, cloxacillin and gentamicin. Furthermore, the 30% Phyllanthus niruri Linn extract is effective as an antibacterial for antibiotic resistance enterotoxigenic E. coli. next necessary to write that: The 30% meniran extract is potential for kill of enterotoxigenic E. coli
Sambiloto (Andrographis paniculata) Extract Improves the Performance of Animal Model Infected with Escherichia coli Sri Hidanah1 , Emy Koestanti Sabdoningrum1 , Mohammad Anam Al Arif1 , Arif Nur Muhammad Ansori2 , Ta
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i4.12167

Abstract

This study aims to understand the effect of natural antibiotics from sambiloto (Andrographis paniculata)extract to laying hens infected with Avian Pathogenic Escherichia coli (APEC). The activation test ofsambiloto was performed by using a dilution method included a minimum inhibitory concentration (MIC)and a minimum bactericidal concentration (MBC). Laying hens were distributed into five groups: normalgroup, APEC group with no treatment, and APEC group given 10%, 20%, 30% sambiloto extract for twoweeks. The data were analyzed using ANOVA and continued with the F test. Based on the results, the 30%extract has improved the hen day production (HDP) of laying hens infected with APEC.
INSEMINASI BUATAN MENGGUNAKAN PERSILANGAN SPERMA LIMOSIN DAN SIMENTAL MELALUI SINKRONISASI BIRAHI SUATU USAHA INTENSIFIKASI REPRODUKSI SAPI UNTUK PENINGKATAN PETERNAKAN SAPI RAKYAT DI KECAMATAN KEDUNGADEM KABUPATEN BOJONEGORO Emy Koestanti Sabdoningrum; Sunaryo Hadi Warsito; Heru Pramono; Siti Eliana
Jurnal Layanan Masyarakat (Journal of Public Services) Vol. 2 No. 1 (2018): Jurnal Layanan Masyarakat
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (187.27 KB) | DOI: 10.20473/jlm.v2i1.2018.6-11

Abstract

The beef cattle breeding business in Kedungrejo village, Kedungadem sub-district, Bojonegoro Regency in general has not implemented an efficient business concept considering that there are many potentials and opportunities that have not been utilized and managed optimally, especially those related to livestock reproduction and beef cattle production. Constraints that are often encountered are the low success rate of Artificial Insemination (IB) of beef cattle because poor quality cement and inseminator skills are not sufficient. Such conditions are also an illustration of the Beef Cattle Breeders in Kedungrejo Village, Kedungadem District, Bojonegoro Regency. Kedungrejo village was chosen to be a place for cattle development on dry land because it has the potential to breed cattle crosses of Lemosin and Simental cattle which produce good meat. The development of cattle in Kedungrejo village, Kedungadem sub-district, aims to increase economic activities in support of cattle reproduction intensification efforts to increase people’s cattle farming. This activity for the community aims to fulfill meat self-sufficiency through the introduction, dissemination, transfer of reproductive technology by artificial insemination using Limousine and Simental sperm crosses. Beef cattle farmers in Kedungrejo Village Kedungadem Bojonegoro Subdistrict have the prospect of beef cattle breeding which can be developed to fulfill meat self-sufficiency that is being promoted. Specific targets of outcomes to be achieved include the success of insemination, increased birth rate, improvement of genetic quality of beef cattle through Artificial Insemination using Limousine and Simental sperm crosses in the Kedungrejo Village, Kedungadem Bojonegoro District. The method used in achieving this goal by socializing Artificial Insemination using Limousine and Simental Sperm Crosses. The solution offered is through the coaching, training and application stages. The results of community service activities indicate that Artificial Insemination using Limousine and Simental Sperm Crosses has the prospect of being developed as an increase in the success of insemination, increased birth rate, genetic quality improvement has a positive influence on beef reproductive and meat self-sufficiency.AbstrakUsaha peternakan sapi potong di desa Kedungrejo Kecamatan Kedungadem Kabupaten Bojonegoro pada umumnya belum menerapkan konsep usaha yang efi sien mengingat banyak potensi dan peluang yang belum dimanfaatkan dan dikelola secara optimal terutama yang terkait reproduksi ternak dan produksi ternak sapi potong. Kendala yang sering dijumpai adalah rendahnya tingkat keberhasilan Inseminasi Buatan (IB) ternak sapi potong karena kualitas semen yang kurang baik dan skill inseminator belum memadai. Kondisi demikian juga merupakan gambaran dari Peternak Sapi Potong Desa Kedungrejo Kecamatan Kedungadem Kabupaten Bojonegoro. Desa Kedungrejo dipilih menjadi tempat pengembangan ternak sapi di lahan kering karena mempunyai potensi untuk pemuliabiakan persilangan sapi Lemosin dan sapi Simental yang menghasilkan daging yang bagus. Pengembangan ternak sapi di desa Kedungrejo Kecamatan Kedungadem bertujuan meningkatkan kegiatan perekonomian dalam mendukung usaha intensifi kasi reproduksi sapi untuk peningkatanpeternakan sapi rakyat. Kegiatan kepada masyarakat ini bertujuan pemenuhan swasembada daging melalui pengenalan, penyebarluasan, alih teknologi reproduksi dengan cara Inseminasi buatan menggunakan persilangan sperma Limousin dan Simental. Peternak sapi potong Desa Kedungrejo Kecamatan Kedungadem Bojonegoro mempunyai prospek peternakan sapi potong yang dapat dikembangkan untuk memenuhi swasembada dagingyang sedang digalakkan. Target khusus luaran yang ingin dicapai berupa keberhasilan inseminasi, peningkatan angka kelahiran, perbaikan mutu genetik sapi potong melalui Inseminasi Buatan menggunakan persilangan sperma Limousin dan Simental di wilayah Desa Kedungrejo Kecamatan Kedungadem Bojonegoro. Metode yang dipakai dalam pencapaian tujuan tersebut dengan sosialisasi Inseminasi Buatan menggunakan Persilangan Sperma Limousin dan Simental. Solusi yang ditawarkan adalah melalui tahap pembinaan, pelatihandan aplikasi. Hasil kegiatan pengabdian kepada masyarakat ini menunjukkan bahwa Inseminasi Buatan menggunakan Persilangan Sperma Limousin dan Simental mempunyai prospek untuk dikembangkan sebagai peingkatan keberhasilan inseminasi, peningkatan angka kelahiran, perbaikan mutu genetik memberi pengaruh positif terhadap reproduktivitas sapi potong dan pemenuhan swasembada daging.
PELATIHAN SUSU PASTEURISASI, YOGHURT DAN CARA PENGEMASANNYA DALAM PENINGKATKAN PENDAPATAN PANTI ASUHAN HIMATUN AYAT Sri Hidanah; Emy Koestanti Sabdoningrum; Anam Al-Arif
Jurnal Layanan Masyarakat (Journal of Public Services) Vol. 5 No. 2 (2021): JURNAL LAYANAN MASYARAKAT
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jlm.v5i2.2021.382-389

Abstract

AbstractHimmatun Ayat was an orphanage located on Jalan Dukuh Kupang, Surabaya, East Java which aimed to build public awareness of orphans, poor people, and neglected children in achieving their goals for a better future. The problems faced by the Himmatun Ayat orphanage during the COVID-19 pandemic were the decline in turnover and market saturation for their products. The solution was to evoke entrepreneurship development during the pandemic with innovation and technology by providing training on the manufacture of various flavors pasteurized milk, yogurt, and packaging methods to increase the economic value of the product so it could increase the income of the Himmatun Ayat Orphanage. The implementation of this activity was carried out by three methods: 1. Counseling, 2. Training, and 3. Monitoring and evaluation. The result obtained from this community service was all participants displayed the results of pasteurized milk and yogurt products as well as good packaging according to what was conveyed. The successful application of technology through community service could increase the income and welfare of the Himmatun Ayat Orphanage.Keywords: pasteurized milk, yogurt, packaging, orphanage, community service. AbstrakHimmatun Ayat merupakan lembaga panti asuhan yang di Jalan Dukuh Kupang, Surabaya, Jawa Timur yang bertujuan membangun kepedulian masyarakat kepada anak-anak yatim, kaum dhuafa dan anak terlantar dalam meraih cita-cita menuju masa depan yang lebih baik.  Permasalahan yang dihadapi panti asuhan Himmatun Ayat saat pandemi COVID-19 ini adalah penurunan omset dan kejenuhan pasar terhadap produk mereka. Solusinya membangkitkan pengembangan kewirausahaan di masa pandemi dengan inovasi dan teknologi dilakukan dengan memberikan pelatihan pembuatan produk susu pasteurisasi aneka rasa, yoghurt dan cara pengemasannya untuk menambah nilai ekonomis produk sehingga meningkatkan pendapatan Panti Asuhan Himmatun Ayat. Pelaksanaan kegiatan ini dilaksanakan dengan tiga metode: 1) Penyuluhan, 2) Pelatihan, dan 3) Monitoringdan evaluasi. Hasil yang didapat dari pengabdian masyarakat ini semua peserta menampilkan hasil produk susu pasteurisasi dan yoghurt serta kemasan yang bagus sesuai dengan yang disampaikan. Keberhasilan pengaplikasian teknologi melalui pengabdian masyarakat ini  dapat meningkatkan pendapatan dan kesejahteraan Panti Asuhan Himmatun Ayat.Kata kunci: susu pasteurisasi, yoghurt, pengemasan, panti asuhan, pengabdian masyarakat. 
The Conformity of Diagnostic Test Between Burrow Ink Test Method With Skin Scrapping Method of Scabies in Rabbit (Lepus domesticus) Fadila Zikri Amanda; Poedji Hastutiek; Emy Koestanti Sabdoningrum; Nunuk Dyah Retno Lastuti; Endang Suprihati; Hana Eliyani
Journal of Parasite Science (JoPS) Vol. 2 No. 1 (2018): Journal of Parasite Science
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (532.383 KB) | DOI: 10.20473/jops.v2i1.16381

Abstract

This study intend to know the conformity of diagnostic test between burrow ink test method with skin scrapping method of scabies in rabbit. Scabies caused by Sarcoptes scabiei which has a predilection in stratum corneum and lucidum. Clinical symptoms was characterized by papula or crusting of the skin. This study presents a laboratory explorative research with cross sectional approach. Samples used 20 rabbits that infested scabies naturally. Data obtained by performing diagnostic burrow ink test method and skin scrapping in rabbits which are infested scabies naturally. KAPPA test used as data analysis. Results showed that the number of positive results based on burrow ink test method are 12 rabbits and 8 rabbits are negative while skin scrapping obtained the positive results are 11 rabbits and 9 rabbits are negative. KAPPA test analysis performed on the overall study data was obtained 0,490. The conclusion of this study is burrow ink test method has a good conformity with the skin scrapping in rabbits which are infested scabies naturally that can be used for diagnostic analysis of scabies with a simple method, faster, and have the same ability with skin scrapping without hurting animals.
Prevalence of Digestive Endoparasites (Helminth and Protozoa) in Domestic Pigeon (Columba livia) Male and Female in Tuban Melanie Aulia Ashfiyah; Setiawan Koesdarto; Hana Eliyani; Mufasirin Mufasirin; Emy Koestanti Sabdoningrum
Journal of Parasite Science (JoPS) Vol. 6 No. 1 (2022): Journal of Parasite Science
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (761.489 KB) | DOI: 10.20473/jops.v6i1.34102

Abstract

This research was conducted to determine the prevalence of major gastrointestinal helminthiasis and protozoal infections, the kinds of helminth and protozoa that infects and the effect of sex on pigeons in Tuban. Pigeons are taken from five The Tuban area is Widang, Montong, Jenu, Soko, Jatirogo. Each area is taken as many as 20 pigeons consists of 10 male pigeons and 10 female pigeons. Laboratory examinations were carried out in November to December 2021. Samples were examined by the native method, sedimentation, and flotation. Identification using a microscope using a 40x objective scale and 10x ocular scale. Data analysis using chi square test statistical analysis. 81% of the samples were positive for helminthiasis infection. Chi square test statistical analysis showed p value 0.022 (p<0.05) which means significantly different. 71% of samples were positive for gastrointestinal protozoa infection in pigeons in Tuban. Chi square test Results Statistical analysis shows p the value of 0.123 (p>0.05) which means that it is not significantly different. Type of protozoa found that Heterakis gallinarum (45%), Ascaridia columbae (42%), Capillaria sp. (41%), and Eimeria sp. (71%). That prevalence of helminthiasis in male pigeons higher (45%) compared to female pigeons (36%).
Co-Authors Adinda Riezki Irawan Agustono Agustono Anam Al-Arif Anita Nur Aida Aida Aprinda Ratna Lovela Arini Rahmi Dewi Benjamin Christoffel Tehupuring Budi Utomo Chusniati, Sri Dadik Rahardjo Dian Ayu Permatasari Endang Suprihati Erma - Safitri ERMA SAFITRI Fadila Zikri Amanda Garry Cores de Vries Hana Eliyani Hana Eliyani Heru Pramono I. Ismudiono Koesnoto Supranianondo Kusnoto Kusnoto Lina Wafia Asmi Melanie Aulia Ashfiyah Moh. Anam Al-Arief Mufasirin Myrna Budi Nanda Kholifatul Azizah Nunuk Dyah Retno Lastuti Poedji Hastutiek Retno Sri Wahyuni Rochmah Kurnijasanti Sarmanu Sarmanu Setiawan Koesdarto Setiawan Koesdarto Siti Eliana Sri Hidanah Sri Hidanah Sri Pantja Madyawati Suherni Susilowati Wahyu Retno Swari Warsito, Sunaryo Hadi Widya Paramita Lokapirnasari Widya Paramitha Lokapirnasari Woro Hastuti Setyantini wurlina wurlina