Article Per Year (5 Year)
p-Index From 2019 - 2024
6.196
P-Index
This Author published in this journals
All Journal Berkala Kedokteran Jurnal Surya Medika Logista: Jurnal Ilmiah Pengabdian Kepada Masyarakat JURNAL PENDIDIKAN MIPA Pharmacoscript Jurnal Farmamedika (Pharmamedica Journal) Jurnal Riset Kefarmasian Indonesia Science Midwifery International Journal of Clinical Inventions and Medical Sciences (IJCIMS) Reswara: Jurnal Pengabdian Kepada Masyarakat Lumbung Farmasi : Jurnal Ilmu Kefarmasian Indonesia Berdaya Hydrogen: Jurnal Kependidikan Kimia Jurnal Sains dan Kesehatan Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Dinamika Kesehatan: Jurnal Kebidanan dan Keperawatan Journal of Pharmaceutical Care and Sciences Jurnal Matematika Dan Ilmu Pengetahuan Alam LLDikti Wilayah 1 (JUMPA) Jurnal Rumpun Ilmu Kesehatan Innovative: Journal Of Social Science Research Sains Medisina Journal of Advances in Medicine and Pharmaceutical Sciences Juragan (Jurnal Agroteknologi) JFARM (Jurnal Farmasi)
Kunti Nastiti
Universitas Sari Mulia
Religion Aerospace Engineering Agriculture, Biological Sciences & Forestry Arts Humanities Astronomy Automotive Engineering Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Control & Systems Engineering Dentistry Economics, Econometrics & Finance Education Electrical & Electronics Engineering Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Mathematics Mechanical Engineering Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Veterinary Other

Published : 47 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 3 Documents
Search
Journal : Science Midwifery

 1 
Anti-Inflammatory Test Macaranga gigantea with Interleukin Inhibitor approach In Silico samsul hadi; kunti nastiti
Science Midwifery Vol 10 No 5 (2022): December: Science Midwifery
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v10i5.869

Abstract

Inflammation is condition inflammation accompanied by pain and fever . _ In general drug anti-inflammatory work with hinder enzyme cyclooxygenase , both COX-1 and COX-2, which play a role in synthesize inflammatory mediators such as prostaglandins and thromboxane . Various study developed for look for agent more therapy effective and have more risk low good symptom inflammation I or consequence period long from disease inflammation chronic . One of the approach taken is develop IL1β inhibitors. Method used is compound screening active using in silico. Docking software used in study this is autodock 4.2 and visualization interaction using discovery studio , materials used in study this is the compounds contained in M. gigantea. Result of research this is the value of delta G is negative below -4 kcal / mol, so reaction yanga occur between the ligand and the protein will walk spontaneous . Conclusion in study this obtained four ligands with lowest G value that is glycasperin A; broussoflavonol F; 5,7,3 ',4'-Tetrahydroxy-3-methoxy-8,5'-diprenylflavone; meliternatin .
Karamunting screening as an antifungal using the In Silico method targeting N-myristoyltransferase Samsul Hadi; Kunti Nastiti
Science Midwifery Vol 10 No 6 (2023): February: Midwifery and Health Sciences
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v10i6.1134

Abstract

Karamunting has been empirically used by the community in overcoming itching disorders due to fungi. Therefore the purpose of this study was to screen in silico the content of Karamunting against N-myristoyltranseferase protein. The method used in this study was In Silico screening using PLANTS docking and the materials used were thirteen compounds contained in Karamunting. The results of this study are docking scores from -123.628 to -77.3801 and residues that have similarities with native ligands when interacting with N-myristoyltransferase, namely one to three amino acids, the predicted value using PASSonline ranges from 0.101 to 0.583. The conclusion of this study was obtained three compounds that have the potential as antifungals with the N-myristoyltransferase inhibitor mechanism, these compounds are α-tocopherol-quinone; α-tocopherol A; blumeatin.
Activity predication of rhodomyrtus tomentosa (Aiton) hassk against ace1 inhibitors Samsul Hadi; Kunti Nastiti
Science Midwifery Vol 11 No 2 (2023): June: Midwifery and Health Sciences
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v11i2.1271

Abstract

ACE is a peptidyl-dipeptidase enzyme that catalyzes the conversion of substrates from angiotensin I to angiotensin II. These changes cause constriction of blood vessels so that blood pressure increases (hypertension), so This study aims to find compounds that have the potential to reduce blood pressure through the pathway of ACE1 enzyme inhibition. The method used is docking, the material used is a compound contained from Rhodomyrtus tomentosa and. The ACE1 protein was obtained from RCSB with the code 1UZF. The equipment used was an online pass webserver, PLNTS software and discovery studio. This research was started by redocking the native ligand to determine the coordinates and radius, followed by validating the docking results. The results of the early stage screening obtained 4 compounds with a threshold value above 0.3, these four compounds were continued with the docking test. The docking scores obtained were Afrormosin (-59.620); Pedunculagin (-45.205); Tomentosine (-70.986); Desgalloylstachyurin (-54.374). The conclusion obtained is that the Tomentosine compound binds most easily to ACE1
Co-Authors Adi Rahmadi Ana Maulana Ana Muliana Arif Subekti Citra Agustiani Kusuma Dahlia Syahrina Darini Kurniawati Darini Kurniawati Darini Kurniawati Dede Mahdiyah Deni Setiawan Desiya Ramayanti Azhara Diah Aulia Rosanti Dian Ekowati Dyan Fitri Nugraha Dyan Fitri Nugraha Dyan Fitri Nugraha Dyan Fitri Nugraha Faisal Rahman Feliya Carolina Firda Nirmalasari Fitri Yuliana Ghina Zhahera Ihda Syifa El Rahma Juliance Yolanda Putri Mambang Maria Dwi Ayu Listiawati Melviani Melviani Melviani Melviani Melviani Melviani Melviani Melviani Melviani Mia Audina Mia Audina Muhammad Noor N Noval N Novia Ni Ketut Linda Puspa Yani Noval Noval Nur Syifa Nurul Hidayah Putri Vidiasari Darsono Rahmadani Rahmadani Rahmayani Rahmayani Rizali, Muhammad Samsul Hadi Setia Budi Setia Budi Siti Malahayati Siti Malahayati Sukmana, M. Laily Qadry Tuti Alawiyah Umi Kalsum Vita Mayasari Witri Alya Yanti Saubari Yanti Saubari