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Comparison between monotherapy and combination therapy among inpatients with community-acquired pneumonia Rike Syahniar; Audia Nizhma Nabila; Dayu Swasti Kharisma; Muhammad Afif Akbar
Jurnal Ilmiah Farmasi Vol. 17 No. 1 (2021): Jurnal Ilmiah Farmasi
Publisher : Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/jif.vol17.iss1.art6

Abstract

Background: Pneumonia causes high mortality, hospitalization costs and health services. There is some growing debate regarding the efficacy of different treatment management approaches. The use of certain antibiotic regimens combination and monotherapy have been associated with improved outcomes.Objective: This study aims to determine the effectiveness of monotherapy and combination therapy on length of stay.Method: This retrospective study included patients with Community Acquired Pneumonia (CAP) who received empirical therapy between January - December 2017 at Jakarta Islamic Hospital of Cempaka Putih. Two hundred and ninety four subjects were included in this study.Results: Subjects who received monotherapy and combination therapy were 73.8% and 26.2%. Mean length of stay was 5 days. The most widely used antibiotic in this study was ceftriaxone with levofloxacin (35%) for combination therapy and levofloxacin (38,2%) for monotherapy. There is a relationship between comorbidities and long-term hospitalization (p=0.008).Conclusion: There was no significant difference between combination therapy and monotherapy with length of stay (p=0.277).Keywords: Pneumonia, monotherapy, combination therapy, Jakarta Islamic Hospital of Cempaka PutihIntisariLatar belakang: Pneumonia menyebabkan tingginya angka kematian, biaya rawat inap dan pelayanan kesehatan. Terdapat beberapa perdebatan yang berkembang mengenai efikasi pendekatan manajemen pengobatan yang berbeda. Penggunaan kombinasi rejimen antibiotik tertentu dan monoterapi telah dikaitkan dengan hasil yang lebih baik.Tujuan: untuk menentukan efektivitas monoterapi dan terapi kombinasi terhadap lama rawatinap.Metode: Penelitian retrospektif ini melibatkan pasien dengan community acquired pneumonia yang menerima terapi empiris antara Januari - Desember 2017 di Rumah Sakit Islam Jakarta (RSIJ) Cempaka Putih.Hasil: Dua ratus sembilan puluh empat subjek dilibatkan dalam penelitian ini. Subyek yang menerima monoterapi dan terapi kombinasi sebesar 73,8% dan 26,2%. Rerata lama rawat inap pada kelompok monoterapi dan dualterapi yaitu 5 hari. Antibiotik yang paling banyak digunakan dalam penelitian ini yaitu seftriakson dengan levofloksasin (35%) untuk terapi kombinasi dan levofloksasin (38,2%) untuk monoterapi. Terdapat hubungan antara komorbid dengan lama rawat inap (p=0,008).Kesimpulan: Tidak terdapat perbedaan bermakna antara terapi kombinasi dan monoterapi dengan lama rawat inap (p=0,277)Kata kunci : Pneumonia, monoterapi, terapi kombinasi, RSIJ Cempaka Putih
Profil Mikrobiota ASI dan Perannya terhadap Saluran Cerna Bayi Rike Syahniar; Auliyani Andam Suri
Muhammadiyah Journal of Nutrition and Food Science (MJNF) Vol 1, No 1 (2020): Muhammadiyah Journal of Nutrition and Food Science (MJNF)
Publisher : Faculty of Medicine and Health Universitas Muhammadiyah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (396.762 KB) | DOI: 10.24853/mjnf.1.1.8-17

Abstract

Latar Belakang: Air susu ibu (ASI) mengandung mikrobiota dalam jumlah banyak yang mewakili bakteri komensal, mutualistik, dan bakteri yang berpotensi sebagai probiotik pada saluran cerna bayi. Hasil: Filum bakteri yang paling dominan dalam ASI antara lain Proteobacteria dan Firmicutes sedangkan pada tingkat genus yaitu Staphylococcus, Pseudomonas, Streptococcus dan Lactobacillus. Diantara berbagai mikrobiota yang terdapat dalam ASI, Lactobacillus dan Bifidobacterium berpotensi sebagai probiotik. Kesimpulan: Mikrobiota usus memberikan fungsi metabolisme, dan proteksi yang bermanfaat seperti peningkatan kapasitas pencernaan, produksi asam lemak rantai pendek dan vitamin, pengaturan struktur mukosa dan sistem kekebalan tubuh serta resistensi kolonisasi terhadap patogen.
PROFIL HEMATOLOGI PASIEN ANAK DENGAN TIFOID SERTA KORELASINYA TERHADAP LAMA RAWAT INAP Rike Syahniar; Khayrul Fikri; Matahari Arumdini; Rayhana Rayhana
Media Kesehatan Politeknik Kesehatan Makassar Vol 15, No 1 (2020): Media Kesehatan
Publisher : Politeknik Kesehatan Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (158.239 KB) | DOI: 10.32382/medkes.v15i1.1210

Abstract

 ABSTRACTLeukopenia, thrombocytopenia and anemia are haematological abnormalities that are usually found in typhoid fever patients. This study aims to determine the relationship between platelet counts, leukocyte counts, hematocrit values and haemoglobin in pediatric typhoid patients. This research is a descriptive and analytic study using the parameters of hematology and length of stay in children at the Jakarta Cempaka Putih Islamic Hospital. The data used are secondary data in the form of medical records of patients from January to June 2018 who were diagnosed with typhoid fever. Data analysis using the Kolmogorov Smirnov and Chi-square test. The average age and length of stay of the patients were 9 years and 4.6 days. Bivariate analysis showed no relationship between length of stay with platelet count (p = 1.000), leukocytes (p = 0.969), hematocrit value (p = 1.000) and haemoglobin (p=0.549). There was no significant relationship between overall hematological parameters and length of hospital stay.Keywords: Length of stay, parameters of hematology, typhoid fever. AbstrakLeukopenia, trombositopenia dan anemia merupakan kelainan hematologis yang biasanya ditemukan pada pasien demam tifoid. Penelitian ini bertujuan untuk mengetahui hubungan antara jumlah trombosit, jumlah leukosit, nilai hematokit dan hemoglobin pada pasien tifoid anak. Penelitian ini merupakan deskriptif dan analitik menggunakan variabel parameter hematologi dan lama rawat pada anak di Rumah Sakit Islam Jakarta Cempaka Putih. Data yang digunakan yaitu data sekunder berupa rekam medik pasien periode Januari – Juni 2018 yang di diagnosis demam tifoid. Analisis data menggunakan uji Kolmogorov Smirnov dan Chi-square. Rata-rata usia dan lama rawat inap pasien yaitu 9 tahun dan 4,6 hari. Analisis bivariat menunjukkan tidak terdapat hubungan antara lama rawat dengan jumlah trombosit (p=1.000), leukosit (p=0.969),nilai hematokrit (p=1.000) dan hemoglobin (p=0.549). Tidak terdapat hubungan yang bermakna antara keseluruhan parameter hematologi dengan lama rawat inapKata kunci: Demam tifoid, lama rawat, parameter hematologi
EDUKASI PERILAKU CERDIK PADA LANSIA DENGAN HIPERTENSI DI WILAYAH KERJA PUSKESMAS BANJAR 1 Indy Zafira Maharani; Mellynia Yuniarti; Neng Ratna Sari; Tri Wahyuni Aulia; Farsida Farsida; Rike Syahniar
Abdi Masyarakat Vol 3, No 2 (2021)
Publisher : Lembaga Penelitian dan Pendidikan (LPP) Mandala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58258/abdi.v3i2.2923

Abstract

In general, hypertension is an asymptomatic condition, namely abnormally high pressure in the arteries causing an increased risk of stroke, heart failure, heart attack, and kidney damage which is the leading cause of chronic heart failure. An unhealthy lifestyle and a history of hypertension can trigger hypertension. The community has an essential role in preventing non-communicable diseases such as hypertension and fostering a culture of clean and healthy living behavior (PHBS) in the community. PHBS on the prevention of non-communicable diseases is implemented through the "CERDIK" activity, an acronym for "Regular health checks, Get rid of cigarette smoke, Diligent physical activity, healthy diet with balanced calories, Adequate rest and Manage stress." The purpose of this community service is to provide counseling to the elderly about CERDIK (regular health checks, getting rid of cigarette smoke, diligent physical activity, healthy diet and balanced nutrition, adequate rest, and managing stress). This activity consists of CERDIK Gymnastics, lectures/counseling, and questions and answers. The output of this activity is expected that the elderly can understand hypertension and apply CERDIK behavior.
THE RELATIONSHIP OF BREASTFEEDING MOTHERS‘ HYGIENE BEHAVIOR WITH THE INCIDENCE OF METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS (MRSA) Aning Subiyatin; Rike Syahniar; Adinta Anandani
Jurnal Riset Kesehatan Vol 11, No 2 (2022): NOVEMBER 2022
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jrk.v11i2.9204

Abstract

Staphylococcus aureus (S.aureus ) is a pathogenic bacterium that can be isolated from breast milk and can cause various infections including pneumonia, sepsis, skin lesions, and food poisoning in infants. This bacterium is present in humans and does not cause any symptoms, but it can serious infections such as sepsis and even death. In nursing mothers, This bacterium is associated with mastitis (breast infection) and abscesses of breasts that require medical attention. The purpose of this study was to determine the factors of breastfeeding behavior with the incidence of MRSA. This research was an analytical observational with a cross-sectional approach to breastfeeding mothers in the South Tangerang area. The sampling technique used purposive sampling on 47 people—data collection using questionnaires and Vitek-2 examination for MRSA. Hygiene behavior in breastfeeding mothers in the good category 27 (57.4%). Four (8.5%) breastfeeding mothers were positive for MRSA. There was no relationship between hygiene behavior in breastfeeding mothers and MRSA (p=1,000). Hygiene behavior in breastfeeding mothers in South Tangerang was in a good category. There were 8.5% of breastfeeding mothers are MRSA-positive. Hygiene behavior in breastfeeding mothers can prevent the transmission of MRSA to infants.
Factors associated with the willingness to receive COVID-19 vaccination among pregnant women Hana Fathiazzahra Jaelani; Rike Syahniar
International Journal of Public Health Science (IJPHS) Vol 12, No 1: March 2023
Publisher : Intelektual Pustaka Media Utama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11591/ijphs.v12i1.21724

Abstract

Pregnant women are a vulnerable group to be infected by COVID-19, and have a higher risk of serious illness, morbidity, and mortality than the general population. Willingness to receive COVID-19 vaccination has a decisive role in successfully controlling the COVID-19 pandemic. The objective of this study was to determine the factors related to the willingness to get COVID-19 vaccination in pregnant women at the Teluknaga Public Health Center. A total of 102 pregnant women with gestational ages of 13 to 33 weeks were selected by convenience sampling. Data were collected by filling out a questionnaire during November to December 2021. All respondents had a health status that meets the requirements for COVID-19 vaccination. Overall, 63% of pregnant women wanted to receive COVID-19 vaccination. There were significant relationships between education (p=0.029), frequency of antenatal care (p=0.019), husband's support (p<0.001) and willingness to receive vaccination. Religion, occupation, knowledge about COVID-19, parity, frequency of antenatal care visits, and sources of information did not show significant relationships with the willingness to receive COVID-19 vaccination among them. Education and awareness campaigns about the safety of the COVID-19 vaccine for pregnant women and the role of health workers are needed to raise awareness.
Instalasi Sistem Informasi Manajemen Klinik - Doctor Tool di Amal Usaha Kesehatan ‘Aisyiyah sebagai Bentuk Kontribusi FKK UMJ terhadap Penguatan Fasilitas Kesehatan Tingkat Primer Oktarina Oktarina; Dayu Swasti Kharisma; Farsida Farsida; Pitut Aprilia; Rike Syahniar; Salma Mardhiyana; Septiana Cahya Nugraha
Jurnal Ilmiah Permas: Jurnal Ilmiah STIKES Kendal Vol 12 No 3 (2022): Jurnal Ilmiah Permas: jurnal Ilmiah STIKES Kendal: Supp Juli 2022
Publisher : Sekolah Tinggi Ilmu Kesehatan Kendal

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (669.728 KB)

Abstract

Sejak diterapkannya Jaminan Kesehatan Nasional, Fasilitas Kesehatan Tingkat Primer (FKTP) dituntut untuk bekerjasama dengan BPJS. Selain itu, FKTP Amal Usaha Kesehatan ‘Aisyiyah (AUKESA) perlu menunjukkan kinerjanya kepada PP ‘Aisyiyah. Sistem Informasi Manajemen (SIM) merupakan salah satu prasarana utama dalam penyelenggaraan pelayanan untuk menunjukkan kinerja disertai bukti yang otentik, valid, dan real time. Instalasi SIM Klinik Doctor Tool dipilih karena memberikan fitur bridging dengan kebutuhan PCare-BPJS sekaligus dapat menyajikan laporan berkala untuk pemantauan performa oleh PP ‘Aisyiyah. Kegiatan ini dilakukan selama 1 tahun oleh inisiasi FKK UMJ dengan kegiatan rapat koordinasi, instalasi SIM Klinik Doctor Tool, dan pelatihan SDM. Modul Doctor Tool yang diinstalasi ini adalah pendaftaran pasien, layanan antrian, pemeriksaan awal, rekam medis dokter, depo farmasi, dan billing. Modul Rekam Medis Dokter sudah mengadopsi Problem Oriented Medical Record mencakup assesmen sesuai ICD10, ICPC2, serta mengakomodir diagnosis holistik, tindakan medis, peresepan, pemeriksaan lab, surat sehat/sakit, rujukan/rujuk balik, dan perencanaan lainnya. Fitur yang dapat dimanfaatkan oleh PP ’Aisyiyah adalah Dashboard yang dirancang untuk melihat performa dan utilisasi klinik. Laporan yang diterbitkan meliputi rekapitulasi peserta terdaftar, statistik kunjungan, demografi, obat, laba-rugi, dan laporan sesuai ketentuan BPJS. Manfaat yang diperoleh bagi FKTP adalah meningkatknya produktifitas, terbukanya kanal pasien baru, efisiensi waktu kerja, integrasi dengan PCare-BPJS, dan kesesuaian dengan standar akreditasi klinik. Sedangkan, manfaat yang diterima oleh PP ‘Aisyiyah adalah pemantauan performa AUKESA dan deteksi dini apabila diperlukan pendampingan teknis lebih lanjut. AUKESA yang baik dapat dimanfaatkan secara mutual bersama institusi pendidikan untuk menjadi wahana pendidikan pelayanan kesehatan tingkat primer.
DIFFERENT ATTITUDES REGARDING THE IMPLEMENTATION OF THE COVID-19 HEALTH PROTOCOL IN TYPE 2 AND NON-DIABETES MELLITUS PATIENTS. Syahniar, Rike; Putri, Annisa Gholiza
Media Kesehatan Politeknik Kesehatan Makassar Vol 17, No 1 (2022): Media Kesehatan
Publisher : Politeknik Kesehatan Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32382/medkes.v17i1.2741

Abstract

Background: Patients with diabetes mellitus (DM) have a poor prognosis if infected with Coronavirus Disease 2019 (COVID-19). Diabetes is associated with increased severity and mortality of COVID-19 disease. Therefore, it is essential for people with diabetes to implement health protocols not to contact SARS-CoV-2, which causes COVID-19.Objective: The purpose of this study was to determine differences in the behavior of implementing the Covid-19 health protocol in patients with type 2 DM and non-DM.Methods: This research is an observational analytic with a cross-sectional approach involving DM and non-DM patients at the Indramayu Regional General Hospital. The research instrument used was a questionnaire and medical record data. P-value <0.05 means statistically significant Results: A total of 120 subjects consisting of 60 patients with type 2 DM and 60 non-DM were willing to participate in the study. Fifty-five people (91.7%) type 2 DM patients and 53 people (88.3%) non-DM patients applied the Covid-19 health protocol behavior with good categories. The results of the Mann-Whitney test show that there are differences in the conduct of implementing the Covid-19 health protocol in patients with type 2 diabetes mellitus and non-diabetes Mellitus at Indramayu Hospital (p-value = 0.000). Conclusion: We conclude that type 2 DM patients are more concerned about preventing the transmission of COVID-19 through good behavior in implementing the COVID-19 health protocol.