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Pengaruh Pemberian Ekstrak Etanol Buah Labu Kuning (Cucurbita moschata D.) Terhadap Penurunan Kadar Asam Urat Pada Mencit Putih Jantan (Mus musculus) Humaira Fadhilah; Riris Andriati; Ahmad Mukhlis Handono
Edu Masda Journal Vol 4, No 1 (2020): Edu Masda Journal Volume 4 Nomor 1
Publisher : STIKes Kharisma Persada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52118/edumasda.v4i1.55

Abstract

Gout is an inflammatory process that occurs because of the accumulation of uric acid crystals around the joint tissue due to serum uric acid levels that exceed its solubility. Hyperuricemia is defined as serum uric acid concentration that exceeds 7 mg / dl. In pumpkin fruit there are chemical constituents such as saponins, flavonoids and tannins Flavonoid activity in pumpkin functions as a decrease in uric acid levels by inhibiting the action of the xanthine oxidase enzyme, some of which can inhibit the enzyme xantin oxidase enzymes as antioxidants (Wahyuni, s., and Wahyu, DS, 2010). to determine the effect of 96% ethanol extract of pumpkin on decreasing uric acid in mice (Mus musculus) .The study was conducted using experimental method. Data used in this study were the rate of decrease in uric acid levels in mice. Conclusion 96% ethanol extract of Yellow Pumpkin ( Cucurbita moschata D.) has the ability to reduce uric acid levels in mice (Mus musculus) in cons entration of 5% (6.1 ± 1.01), concentration of 10% (7.8 ± 1.58), concentration of 20% (4.7 ± 0.51). It is suggested that further research needs to be done to increase the dose concentration to find out more effects that affect the decrease in uric acid in mice.Keywords: Cucurbita moschataDecreased  urin acid Mice (Mus musculus)PumpkinUrin AcidABSTRAKPenyakit Gout merupakan suatu proses inflamasi yang terjadi karena penumpukan kristal asam urat pada sekitar jaringan sendi akibat kadar asam urat serum yang melebihi kelarutannya. Hiperurisemia didefinisikan sebagai konsentrasi asam urat dalam serum yang melebihi 7 mg/dl. Labu kuning (Cucurbita moschata)  dipercaya secara tradisional dapat menurunkan kadar asam urat. Pada buah labu kuning terdapat kandungan kimia seperti saponin, flavonoid dan tanin Aktivitas flavonoid pada labu kuning berfungsi sebagai penurunan kadar asam urat dengan cara menghambat kerja enzim xantin oksidase, beberapa flavonoid selain dapat  menghambat enzim enzim xantin oksidase juga bersifat sebagai antioksidan (Wahyuni, s., dan Wahyu, D.S., 2010). Penelitian ini bertujuan untuk mengetahui efek ekstrak etanol 96%  labu kuning terhadap penurunan asam urat pada mencit (Mus musculus). Penelitian dilakukan dengan metode eksperimen, Data yang di gunakan dalam penelitian ini adalah angka penurunan kadar asam urat pada mencit. Kesimpulan  ekstrak etanol 96% Labu Kuning (Cucurbita moschata D.) memiliki kemampuan untuk menurunkan kadar asam urat pada mencit (Mus musculus) pada konsentrasi 5% (6,1 ±1,01),  konsentrasi 10%(7,8±1,58), konsentrasi 20% (4,7±0,51). Disarankan penelitian selanjutnya perlu dilakukan peningkatan konsentrasi dosis untuk mengetahui efek yang lebih berpengaruh terhadap penurunan asam urat pada mencitKata Kunci: Cucurbita moschataPenurunan asam uratMencit (Mus musculus)Labu kuningAsam urat
RIWAYAT HIPERTENSI DENGAN PENYAKIT JANTUNG PADA PASIEN YANG PERNAH TERPAPAR COVID 19 Riris Andriati; Beti Rianti; Rita Dwi Pratiwi
Edu Masda Journal Vol 6, No 1 (2022): Edu Masda Journal Volume 6 Nomor 1
Publisher : STIKes Kharisma Persada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52118/edumasda.v6i1.156

Abstract

The increase in the number of Covid-19 cases occurred so quickly. Indonesia is one of the countries affected by Covid-19 with data on 228,993 confirmed cases of Covid-19 from March 2, 2020 to September 16, 2020 with the addition of 3,963 new cases, 9,100 deaths (CFR 4.0%), recovered cases 164,101 (71.2%) and 55,792 cases under treatment 24.4%. The objective of study was to determine whether there is a relationship between a history of hypertension and heart disease in patients who have been exposed to Covid 19 in the South Tangerang area. The research method in this research is quantitative research, a cross sectional design, with a sample of 57 respondents. From the results of the study, the average respondent with a history of hypertension and a history of heart disease was around 41-50 years old as many as 23 people (40,4%) with an average value of 2,70 and a standard deviation of 0,91. Meanwhile, the average respondent who had been exposed to Covid with a history of heart disease and hypertension was 29 men. The results of statistical tests obtained p-value 0.015, so there is a relationship between a history of hypertension and heart disease in patients who have been exposed to Covid-19 in the South Tangerang area. Suggestions of this study are expected that educational institutions can improve and determine various educational programs that can disseminate information about Covid-19, especially for people who have a history of heart disease and hypertension. So that the number of Covid-19 exposures does not increase.ABSTRAKPenambahan jumlah kasus Covid-19 terjadi begitu cepat. Indonesia salah satu negara yang terkena dampak Covid-19 dengan jumlah data kasus terkonfirmasi Covid-19 228.993 dari 2 Maret 2020 sampai dengan per 16 September 2020 dengan penambahan kasus 3.963 kasus baru, 9100 kasus meninggal (CFR 4,0%), kasus sembuh 164.101 (71,2%) dan 55.792 kasus dalam perawatan 24,4%. Tujuan penelitian ini adalah untuk Mengetahui  Hubungan Antara Riwayat Hipertensi Dan Penyakit Jantung Pada Pasien Yang Pernah Terpapar Covid 19 di Wilayah Tangerang Selatan. Metode penelitian dalam penelitian ini adalah penelitian kuantitatif, desain cross sectional dengan sampel sebanyak 57 responden. Dari hasil penelitian diperoleh responden dengan riwayat hipertensi dan riwayat penyakit jantung berumur sekitar 41 – 50 tahun sebanyak 23 orang (40,4%) dengan nilai rata-rata 2,70 dan standar deviasi 0,91. Sedangkan sebagian besar responden yang pernah terpapar Covid dengan riwayat penyakit jantung dan hipertensi berjenis kelamin laki-laki sebanyak 29 orang. Hasil uji statistik diperoleh nilai p-value 0,015 artinya ada hubungan antara riwayat hipertensi dengan penyakit jantung pada pasien yang pernah terpapar Covid-19 di wilayah Tangerang Selatan, diharapkan penelitian ini dapat dijadikan sebagai pedoman oleh perawat dalam memberikan pendidikan kesehatan kepada pasien yang terpapar Covid 19 dengan riwayat penyakit hipertensi dan penyakit jantung.
Analisis Determinan Kepatuhan Menjalani Hemodialisa Dengan Kualitas Hidup Pasien Gagal Ginjal Kronik Riris Andriati; Aisyah Aisyah
Edu Masda Journal Vol 5, No 1 (2021): Edu Masda Journal Volume 5 Nomor 1
Publisher : STIKes Kharisma Persada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52118/edumasda.v5i1.111

Abstract

In 2015, the number of cases of end stage chronic kidney failure in Indonesia was 70 thousand sufferers. Based on these figures, patients undergoing hemodialysis therapy are only 4000 to 5000 patients with renal failure. The objective of this study was to determine the relationship between adherence to hemodialysis therapy and the quality of life of patients with chronic renal failure in the Hemodialysis Unit of Haji Hospital Jakarta. This research method is a quantitative study with a cross-sectional design. The number of samples was 54 people who were in the hemodialysis unit of the Jakarta Hajj Hospital during the last three months. The results of the study Respondents with good quality of life, moderate compliance were 1 respondent (%), and good quality were 10 respondents (%). The results of bivariate analysis using the Chi Square test, obtained p value = 0.468˃0.05. This means that there is no relationship between compliance undergoing hemodialysis with the quality of life of patients at the Jakarta Hajj Hospital.
Waktu Tunggu Pelayanan Resep Pasien Rawat Jalan di Rumah Sakit Umum Kota Tangerang Selatan Tahun 2018 Humaira Fadhilah; Devi Novita Indriyani; Riris Andriati
Edu Masda Journal Vol 3, No 1 (2019): Edu Masda Journal Volume 3 Nomor 1
Publisher : STIKes Kharisma Persada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52118/edumasda.v3i1.26

Abstract

 One of the pharmaceutical care standard in hospital is waiting time. The prescribed service waiting time is the time period under which the prescription begins to be delivered by the patient to the patient receiving the drug. The purpose of this research is to know the waiting time of prescription service at Pharmaceutical Installation of South Tangerang City General Hospital compared with minimum service standard of Hospital based on Health Minister Decree No. 129 / MenkesSK / II / 2008. This research is descriptive research, the researcher only make observation to prescription service waiting time. The research was conducted in Pharmaceutical Installation RSU South Tangerang City in March 2018. The sample in this research is recipe served from outpatient in march 2018. Sampling technique in this research is total sampling. The sample obtained 129 consisting of 97 non-prescribed recipes and 32 prescription recipes. From this study, the average total waiting time of prescription service was 48.37 minutes for non-prescribed recipes and 173.38 minutes for prescription recipe. The average waiting time for non-prescribed and concocted prescription services did not meet the minimum hospital service standards pursuant to Kepmenkes RI. 129 of 2008.
Kerasionalan Penggunaan Obat Jantung Coroner Pada Pasien Jantung Koroner Dewasa Rawat Jalan Di RSU Kota Tangerang Selatan Periode Agustus – Oktober 2018 Humaira Fadhilah; Sriwulan Ayuningtyas; Riris Andriati
Edu Masda Journal Vol 2, No 2 (2018): Edu Masda Journal Volume 2 Nomor 2
Publisher : STIKes Kharisma Persada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52118/edumasda.v2i2.17

Abstract

ABSTRAKPenyakit jantung koroner (PJK) merupakan penyebab utama dan pertama dari seluruh kematian, yakni sebesar 26,4%, angka ini empat kali lebih tinggi dari angka kematian yang disebabkan oleh kanker (6%) dan disebabkan adanya penyempitan dan penyumbatan pembuluh darah yang mengalirkan darah ke otot jantung. Tujuan penelitian ini yaitu untuk Mengetahui kerasionalan penggunaan obat jantung koroner pada pasien jantung koroner dewasa di instalasi rawat jalan RSU Kota Tangerang Selatan Periode Agustus – Oktober Tahun 2017. Penelitian ini dilakukan dengan rancangan penelitian berupa deskriptif dengan pendekatan Retrospektif. Pengambilan sampel dilakukan menggunakan metode Simple Random Sampling dengan jumlah sampel sebanyak 85 rekam medis pasien dari populasi 582 rekam medis pasien. Berdasarkan hasil penelitian menunjukkan bahwa karakteristik pasien berdasarkan usia yang terbanyak pada kelompok usia 56-65 tahun sebanyak 32 pasien (37,65%). Karakteristik pasien berdasarkan Jenis kelamin penggunaan obat jantung koroner terbanyak adalah laki-laki sebanyak 62 pasien (72,94%). Persentase kerasionalan penggunaan obat meliputi tepat indikasi (100%), tepat obat (100%), tepat dosis (94,12%), dan tepat pasien (100%). Berdasarkan hasil penelitian ini, diperoleh kesimpulan bahwa kerasionalan penggunaan obat jantung koroner pada pasien jantung koroner dewasa di instalasi rawat jalan di Rumah Sakit Umum Daerah Kota Tangerang Selatan 94,12% sudah rasional. Kata Kunci: Evaluasi Penggunaan Obat, PJK, Rawat Jalan.  ABSTRACTCoronary heart disease (CHD) is the leading cause and the first of all deaths, which is 26.4%, this figure is four times higher than the number of deaths caused by cancer (6%) and due to the narrowing and blockage of blood vessels that drain blood to the heart muscle, so the heart muscle will lack blood. The objectif of this research is to know rationality of coronary heart drug usage in adult coronary heart patient at outpatient installation of RSU Kota Tangerang Selatan Period August - October 2017. This research is done in a descriptive research design with Retrospective approach. The sampling is done by using Simple Random Sampling method with sample of 85 patients in total from 582 patients. Based on a research about drugs evaluation on adult coronary heart disease patients in outpatient installation of public hospital in south tangerang within August-October 2017, it shows that a characteristic of patient in terms of age are coming from age of 56-65 years old with 32 patients (37.65%). A characteristic of patient in terms of gender are coming from male with 62 patients (72.94%). The rationality percentage of drug usage covers precise indications (100%), precise drugs (100%), pricise dose (94.12%), and pricise patient (100%). The conclusion of this research is the rationale of coronary heart drug use in adult coronary heart patients in outpatient treatment at Tangerang Selatan Regional General Hospital 94.12% has been rational. Keywords: Evaluation of drug use, CHD, Outpatient
ANALISIS DETERMINAN TEKNIK PEMASANGAN INFUS DENGAN KEJADIAN FLEBITIS Riris Andriati; Fenita Purnama Sari Indah; Agit Prawida
Edu Masda Journal Vol 5, No 2 (2021): Edu Masda Journal Volume 5 Nomor 2
Publisher : STIKes Kharisma Persada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52118/edumasda.v5i2.126

Abstract

Installation of an appropriate infusion is a procedure whose steps are taken in a hospital. This action will be qualified by its implementation if it refers to the fixed procedure for infusion. If this procedure is not done properly it will cause phlebitis. The purpose of this study was to determine the relationship between the implementation of infusion and the incidence of phlebitis in the inpatient ward of the Banten General Hospital. This research method used a correlational method with a cross sectional approach. The aim is to determine the relationship between the dependent variable and the independent variable, the data is collected by means of observation. The number of samples in this study amounted to 30 people consisting of 30 implementing nurses and 30 patients who had an IV infusion on 17 to 23 June 2019 selected by probability sampling with a simple random technique. The results showed that almost all of the respondents (86.6%) had the infusion done well, and most (43.3%) of the patients who had the infusion did not experience phlebitis. Based on the results of statistical tests, it was found that there was no relationship between the implementation of infusion and the incidence of phlebitis, p value = 0.061. It can be concluded that there is no relationship between the infusion technique and the incidence of phlebitis.  ABSTRAKPemasangan infus yang sesuai merupakan prosedur yang tahapan tindakannya dirumah sakit. Tindakan ini akan berkualitas dengan pelaksanaannya apabila mengacu pada prosedur tetap pemasangan infus. Jika prosedur ini tidak dilakukan dengan baik maka akan menimbulkan flebitis. Tujuan penelitian ini adalah mengetahui hubungan pelaksanaan pemasangan infus dengan kejadian flebitis diruang rawat inap Rumah Sakit Umum  Banten. Metode penelitian ini menggunakan metode korelasional dengan pendekatan cross sectional. Tujuannya untuk mengetahui hubungan antara variabel dependen dan variabel independen, data dikumpulkan dengan cara observasi. Jumlah sampel dalam penelitian ini berjumlah 30 orang terdiri dari 30 perawat pelaksana dan 30 pasien yang terpasang infus pada tanggal 17 sampai dengan 23 Juni 2019 dipilih secara probability sampling dengan teknik simple random. Hasil penelitian menunjukan hampir seluruh responden (86,6%) pemasangan infus dilakukan dengan baik, dan sebagian besar (43,3%) pasien yang terpasang infus tidak mengalami flebitis. Berdasarkan hasil uji statistik diperoleh hasil tidak ada hubungan antara pelaksanaan pemasangan infus dengan kejadian flebitis p value =0.061. Maka dapat disimpulkan bahwa tidak ada hubungan antara teknik pemasangan infus dengan kejadian flebitis.
Evaluasi Penggunaan Obat Sitostatika Ditinjau Dari Berbagai Literatur Nurwulan Adi Ismaya; Riris Andriati; Tri Okta Ratnaningtyas; Nur Hasanah; Dewi Yulianti
Edu Masda Journal Vol 5, No 1 (2021): Edu Masda Journal Volume 5 Nomor 1
Publisher : STIKes Kharisma Persada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52118/edumasda.v5i1.113

Abstract

Cancer is a non-communicable disease, or NCD (Noncommunicable diseases). It becomes a second causative factor of mortality in global. In some cases and scientific journals that show a high problem of drug use in cancer patients. The purpose of this research is to identify the use of sitostatica drugs which are reviewed from a variety of literature. This study uses literature study research. Literature study is a research conducted by researchers by collecting a number of library data relating to the problem and research objectives. Result showed there are the most inaccurate drug diagnosis criteria for patients are 16 cases (22.86%). Inaccuracy in most doses is 21 cases (29.18%). the most inaccurate dose inaccuracy is 127 cases (36.38%), inaccurate indications include the need to add drugs the most is 26 cases (25.49%), drugs without the most indications are 11 cases (10.78%) , inaccurate duration of administration of the most drugs is 15 cases (23.43%), the criteria for alerting for the most side effects are 208 cases (59.59%) the right criteria for the administration method is 100%, the patient is 100% right, and the right submission (dispensing) and information at 100%.
Analisis Standar Perencanaan dan Pengadaan Obat di Apotek Maleo Bintaro Nurwulan Adi Ismaya; Riris Andriati; Lilis Suryani Butar Butar
Edu Masda Journal Vol 4, No 1 (2020): Edu Masda Journal Volume 4 Nomor 1
Publisher : STIKes Kharisma Persada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52118/edumasda.v4i1.58

Abstract

Selection and procurement isan important for drugs  in health service. In Maleo Bintaro’s pharmacy, the lateness in fulfilling the needs of medicine because of the industry void, the lateness for the invoice payment and also PBF facilities and infrastructure which is not fast enough cause the inefficient service towards the society. The purpose of these research is to know howdrug’s selection  and procurement in MaleoBintaro pharmacy. This research is descriptive research by retrieving data retrospectively. These are qualitative and quantitative data, also interviews with the related parties. The stage of selection and procurement efficiency is measured by using the indicators which are released by the Ministry of Health (DEPKES) RI in 2002 and Pudjaningsih in 1996. The conclusion of this research is from the 5 indicators which can be measured; 2 indicators have not met the standard yet. First, in the selection stage, the suitability value of the available drugs with DOEN showed 6,78% as the result, and the incomplete letter of the order or the contract showed the result for 12 times. On the other hand, the 3 other indicators which are the frequency of procuring drug items, the lateness in payment from the pharmacy to the specified time, and also the percentage of the number of drugs that are held and planned are effective according to the standard.
RASIONALITAS OBAT ANTI TUBERKULOSIS PADA PASIEN TB PARU RAWAT INAP DI RUMAH SAKIT UMUM KOTA TANGERANG SELATAN Nurwulan Adi Ismaya; Riris Andriati; Aripin Aripin; Tri Okta Ratnaningtyas; Faizah Tafdhiila
Edu Masda Journal Vol 5, No 2 (2021): Edu Masda Journal Volume 5 Nomor 2
Publisher : STIKes Kharisma Persada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52118/edumasda.v5i2.127

Abstract

One of disease that continues to be a major global health issue is Tuberculosis. This research aims to evaluate a rational of anti-tuberculosis drugs with patient in pulmonary TB at South Tangerang City General Hospital in 2020. The research design was carried out using a descriptive research method. Descriptive research method is carried out with aapproach retrospective. A total sampling technique was used to collect data from 124 patients. According to the study's findings, the age characteristics of the majority of tuberculosis patients were in late adults 36-45 years as many as 28 patients (22.58 percent), and the majority of gender characteristics were male as many as 83 patients (66.93%), diagnoses and diseases The most co-morbidities of tuberculosis patients were pulmonary TB + Type 2 DM patients with a total of 19 patients (15.32%), the category of treatment for the most tuberculosis patients was in category 1, which was 105 patients (84.67%). Presentation of drug rationale includes 100% correct diagnosis, 100% correct indication, 100% correct drug, 88.70% correct dose, 100% correct route of administration, 98,38% correct time interval, and 100% correct patient. It is possible to conclude that the evaluation of the use of anti-tuberculosis drugs in pulmonary TB patients at South Tangerang City General Hospital's Inpatient Installation is not rational.ABSTRAKSalah satu penyakit menular yang masih menjadi masalah utama kesehatan yaitu Tuberkuloasis. Penelitian ini bertujuan untuk menganalisa kerasionalan obat anti tuberkulosis pada pasien TB paru Rawat Inap di Rumah Sakit Umum Kota Tangerang Selatan Tahun 2020. Penelitian ini adalah penelitian deskripti dengan pendekatan kuantitatif. Data yang digunakan adalah data retrospektif yaitu data tahun 2020 dan pengambilan sampel dilakukan dengan menggunakan teknik total sampling dengan jumlah 124 pasien. Hasil penelitian ini, usia pasien tuberkulosis terbanyak yaitu pada dewasa akhir 36-45 tahun sejumlah 28 pasien (22,58%), pasien terbanyak adalah laki-laki 83 pasien (66,93%), diagnosa dan penyakit penyerta terbanyak pasien tuberkulosis yaitu terdapat pada pasien TB Paru + DM Tipe 2 dengan jumlah 19 pasien (15,32%), kategori pengobatan pada pasien tuberkulosis terbanyak yaitu pada kategori  1  yaitu sebanyak 105 pasien  (84,67%). Presentasi kerasionalan obat meliputi tepat diagnosis 100%, tepat indikasi 100%, tepat obat 100%, tepat dosis 88,70%, tepat cara pemberian 100%, tepat interval waktu pemberian 98,38%, dan tepat pasien 100%. Dapat disimpukan bahwa penggunaan obat anti tuberkulosis pada pasien TB paru rawat inap RSU Kota Tangerang Selatan belum rasional. 
Determinan Adversity Quotient dan Kemampuan Berpikir Kritis Dengan Stres Pada Mahasiswa Yang Sudah Bekerja Riris Andriati; Fenita Purnama Sari Indah; Renti Yunita
Edu Masda Journal Vol 4, No 2 (2020): Edu Masda Journal Volume 4 Nomor 2
Publisher : STIKes Kharisma Persada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52118/edumasda.v4i2.105

Abstract

The incidence of stress was quite high, reaching more than 350 million people in the world and ranked 4th in the world. The purpose of this study was to determine the relationship between adversity quotient and critical thinking ability with stress on nursing students in the Widya Dharma Husada Tangerang School of Health Science who are already working. The method of this research was analytic study with a cross sectional approach. The number of samples was 96 students at Widya Dharma Husada Tangerang School of Health Science in 2020. Sampling used non-probability sampling techniques with purposive sampling. The results showed that respondents had a moderate adversity quotient of 48 respondents (50%) and respondents who think critically are not good as many as 61 respondents (63,5%). Statistical test results obtained the, then it can be concluded that there is a significant relationship between adversity quotient with stress (p-value = 0.004) and critical thinking skills with stress (p-value = 0.015)