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Pengaruh Metode Pengeringan Terhadap Kualitas Ekstrak dan Kadar Flavonoid Total Ekstrak Etanolik Daun Sambung Nyawa (Gynura Procumbens (Lour.) Merr.) Margareta Retno Priamsari; Maria Mita Susanti; Andreas Harya Atmaja
Jurnal Farmasi (Journal of Pharmacy) Vol 5, No 1 (2016): Oktober
Publisher : SEKOLAH TINGGI ILMU KESEHATAN NASIONAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37013/jf.v5i1.32

Abstract

                                                       AbstractFlavonoid adalah salah senyawa aktif dalam daun sambung nyawa (Gynura procumbens (Lour.) Merr.) yang memiliki khasiat sebagai antioksidan, menghambat pertumbuhan sel kanker, dan menjaga fungsi hati. Banyaknya khasiat dari flavonoid membutuhkan penanganan pasca panen yang tepat karena sifat flavonoid yang tidak stabil pada suhu tinggi. Penelitian ini bertujuan untuk mengetahui pengaruh metode pengeringan terhadap kualitas ekstrak dan kadar flavonoid total ekstrak etanolik sambung nyawa. Jenis penelitian ini adalah eksperimental. Metode pengeringan dilakukan dengan diangin-angin di bawah tempat teduh terlindung dari sinar matahari langsung dan pengeringan oven suhu 40o C. Analisis kualitas ekstrak yang dilakukan meliputi organoleptis, rendemen dan susut pengeringan. Analisis kadar flavonoid menggunakan metode kolorimetri dengan senyawa pengkompleks AlCl3 dan baku standar kuersetin. Kurva kalibrasi dibuat 5 seri konsentrasi yaitu 40, 60, 80, 100, dan 120 ppm. Absorbansi pada panjang gelombang 434 nm menggunakan spektrofotometer UV Vis. Data yang diperoleh berupa kadar flavonoid selanjutnya dianalisis statistik dengan independent pair sample t-test. Hasil penelitian menunjukkan bahwa metode pengeringan simplisia dapat mempengaruhi kualitas ekstrak dan kadar total flavonoid ekstrak etanolik daun sambung nyawa secara signifikan. Kadar flavonoid total ekstrak etanolik daun sambung nyawa metode pengeringan angin-angin sebesar 2,15 ±0,03% b/b sedangkan kadar flavonoid total ekstrak etanolik daun sambung nyawa metode pengeringan oven 40o C sebesar 1,87 ±0,01% b/b. Total kadar flavonoid dihitung sebagai kuersetin.
Kualitas Mutu Sabun Cair Organik Berbahan Dasar Minyak Jarak Dan Soda Qie Priskalia Inge Sriwening; Maria Mita Susanti
Indonesian Journal on Medical Science Vol 9 No 2 (2022): IJMS 2022
Publisher : Unit Penelitian dan Pengabdian Masyarakat Politeknik Kesehatan Bhakti Mulial

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (862.296 KB) | DOI: 10.55181/ijms.v9i2.370

Abstract

Liquid soap is an important need for many because this soap can clean the dirt that sticks to the skin. Formation of soap due to the process of saponification. Saponification process there needs to be oil and bases as the main raw materials it's castor oil as an oil phase. The base used in the manufacture of liquid soap is Soda qie, which is extracted from the peel of the boar. Sodium carbonate was 26.27%, and sodium hydroxide was 4.37%. The purpose of this study was to see the quality of the cast-based liquid soap and the ashes of the husk skin including organoleptic tests, pH, foam power, free alkali, and viscosity. The kind of research used was explorative research with comparing results here. Liquid soap quality testing methods based on castor oil and soda qie include organoleptic tests, pH tests, tests Viscosity, foam power test, free alkali test, and identification of potassium Soda die. The results are descriptive and presented in the form of a chart. The results of the quality liquid soap are based on castor oil and soda qie. Did not meet the quality of SNI 06-4085-1996, received power test foam at 2,23cm, pH test at 9,9 and viscosity 1193. The alkali tests are free not met quality requirements determined by results of 0,75%.
ANALISIS PENGARUH PERENDAMAN LARUTAN KULIT SINGKONG (Manihot esculenta Cortex) TERHADAP KANDUNGAN LOGAM BERAT TIMBAL (Pb) DALAM KERANG DARAH (Anadara granosa) Maria Mita Susanti; Margareta Retno Priamsari
Media Farmasi Indonesia Vol. 12 No. 2 (2017): Media Farmasi Indonesia
Publisher : SEKOLAH TINGGI ILMU FARMASI YAYASAN PHARMASI SEMARANG

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (440.435 KB)

Abstract

ABSTRACKMussles blood (Anadara granosa) is a type of shell that is often consumed by Indonesian community. The shells have non selective feeder and sessile filter that relatively high which mean heavy metal content is found in the shell’s body due to the accumulation of the heavy metals. In an effort to reduce heavy metals in mussles blood, it can be done using the utilization of cassava skin waste. Cassava skin can be used as a material of reducing the heavy metal content of Pb (Lead) in mussles because it contains cellulose that can modify the group to produce hydroxyl which can bind Pb metal ions. This research aimed to analyze the effect of soaking of cassava skin solution (Manihot esculenta Cortex) with decreasing level of heavy metal lead (Pb) on mussles blood (Anadara granosa). This was an experimental research with treatment of cassava skin concentration of 1%, 1.5% and 3% and soaking time 10 minutes, 40 minutes and 80 minutes. The independent variables are concentration of cassava skin solution, soaking time and dependent variable in this research is Pb concentration in mussles blood (Anadara granosa). Samples were analyzed using an Atomic Absorption Spectrophotometer (SSA). The data were analyzed using Kendall's Tau test. The results showed that there was influence of decreasing percentage of heavy metal Pb on soaking time (p <0.05) but did not affect to concentration of cassava skin solution (p> 0.05).
ANALISIS KARAKTERISTIK MUTU SABUN TRANSPARAN BEKATUL BERAS MERAH (Oryza nivara) BERBAHAN DASAR MINYAK GORENG BEKAS Maria Mita Susanti; Syela Puspitaningtyas
Jurnal Ilmu Farmasi dan Farmasi Klinik Vol 16, No 02 (2019): Jurnal Ilmu Farmasi & farmasi Klinik Vol 16 No 02 Desember 2019
Publisher : Universitas Wahid Hasyim Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (395.512 KB) | DOI: 10.31942/jiffk.v16i02.3235

Abstract

ABSTRACT The free radicals exposure from daily activities can cause the damage the skin, therefore to avoid this damage effect can use antioxidants compounds . Brown rice bran is rice milling waste which has high antioxidant with IC50 is 43,2349 ppm. Efforts to increase the economic value of rice bran high in antioxidant compounds is by processing rice bran into transparent soap products. This research was conducted to analyze the quality characteristics of transparent red rice bran soap (Oryza nivara) based on used cooking oil. The quality characteristics of transparent rice soap which includes organoleptic soap, pH, foam power, free alkali, and water content. The data were analyzed descriptively by comparing the results of research with SNI 06-3532 -1994 Based on the results of the study obtained the results of the characteristics of soap that meets the quality characteristics of SNI 06-3532-1994 soap requirements with a pH of 10,2 , foam power of 2,54 cm, free alkali of 0,034%, and 3,85% moisture content. Keywords : transparent soap, brown rice bran, used cooking oil, solid soap quality characteristics
PENGARUH VARIASI KONSENTRASI KATALIS ASAM SULFAT PEKAT TERHADAP HASIL DERAJAT ESTERIFIKASI ETIL LAURAT admjurnalsiji polibara; Maria Mita Susanti; Jessica Margareta Jaya
Jurnal Ilmiah Medsains Vol 6 No 2 (2020): Edisi Desember
Publisher : Unit Penelitian dan Pengabdian Masyarakat, Politeknik Banjarnegara

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (193.143 KB)

Abstract

Ethyl laurate can be synthesized through an esterification process by reacting lauric acid and ethanol plus H2SO4(p) as a catalyst. The esterification reaction requires a catalyst to accelerate the reaction besides the influence of the addition of the catalyst concentration also affects the ester results so it is necessary to do research that aims to determine the effect of catalyst H2SO4(p) concentration on the results of ethyl lauric esterification. This type of research is an experimental study to determine the effect of variations in H2SO4 catalyst concentration on the synthesis results of ethyl laurate. The experimental design used in this study was a factorial Completely Randomized Design (CRD), which was a comparison of the variation in catalyst H2SO4(p) concentration. The variables observed were variations in H2SO4 (1%, 2%, 3%, 4% and 5%) catalyst concentrations on the esterification degree reacted for 5 hours with a comparison of the variation of the molar ratio of lauric acid and ethanol used 1: 7. Analysis of statistical data obtained was tested using the Oneway Anova test. The results showed that variations in H2SO4(p) catalyst concentration had an effect on the results of the esterification degree. The best degree of esterification was obtained at concentration catalyst H2SO4(p) 4%, which amounted to 90.24%. Statistical data analysis obtained a significant value of 0,000 (p <0.05) which means that there is an influence of variations in the catalyst concentration on the synthesis results of ethyl laurate. Keywords: H2SO4(p) Catalyst Consentration, Ethyl Laurate, Esterification Degree.
PENGARUH TEMPAT TUMBUH TERHADAP KADAR LOGAM BERAT TIMBAL (Pb), CADMIUM (Cd) dan TEMBAGA (Cu) EKSTRAK RIMPANG JAHE EMPRIT (Zingiber officinale Var. amarum) DENGAN METODE SPEKTROFOTOMETRI SERAPAN ATOM Maria Mita Susanti; Dita Dwi Ariyanti; Silvi Ardianti; Wieke Febriawan Citra Mahanani
Jurnal Inovasi Teknik Kimia Vol 8, No 1 (2023)
Publisher : Fakultas Teknik Universitas Wahid Hasyim

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31942/inteka.v18i1.8093

Abstract