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The Activities of Antifertility Ethanol Extract Guava Leaves (Psidium Guajava L.) based on The Analysis Of Cement and Display of Immunohistochemistry Cyclooxygenase-2 In Testis Of Mice (Mus Musculus L.) RICA VERA BR TARIGAN; M. PANDAPOTAN NASUTION; SRY SURYANI WIDJAJA
JURNAL ILMU KEFARMASIAN INDONESIA Vol 14 No 2 (2016): JIFI
Publisher : Fakultas Farmasi Universitas Pancasila

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Abstract

Population growth increase, without support from good economic conditions, requirer population control. One of the program to control population growth is family planning program (KB). The participation of men in family planning programs is very important. Male contraception can utilize natural materials derived from plants. One of the herb is guava leaves (Psidium guajava L.) which contains many active substances that can inhibit the process of spermatogenesis. The purpose of this study was to determine the effect of ethanol extract guava leaves to the quality (concentration, viability, morphology, and motility) of spermatozoa and the expression of Cyclooxygenase-2 (COX-2) in the testes of mice (Mus musculus L.). The research used experimental design with completely randomized sampling method. Four treatment groups, namely P0 using aquadest as a control 0,5 mL, P1 using 15 mg/25g body weight extract orally, P2 using 20 mg/25g body weight extract orally, and P3 using 25 mg/25g body weight extract orally. Data were analyzed using One Way ANOVA followed by Bonferroni Post Hoc test 5%. The results showed that ethanol extract guava leaves with a dose of 15mg/25g body weight had significantly decreased sperm quality and increased expression of COX-2 in the testes of mice. This research indicates that guava leaves have a potential to be used as a herbal contraceptive.
PENINGKATAN PENGETAHUAN TENTANG KESELAMATAN DAN KESEHATAN KERJA DI GEMA KASIH GALANG David Sumanto Napitupulu; Jagentar P. Pane; Amando Sinaga; Lindawati Simorangkir; Rica Vera br Tarigan; Jev Boris
SELAPARANG Jurnal Pengabdian Masyarakat Berkemajuan Vol 6, No 2 (2022): Juni
Publisher : Universitas Muhammadiyah Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/jpmb.v6i2.8678

Abstract

ABSTRAKKaryawan Mebel di Pusat Rehabilitasi Kusta Gema Kasih Galang banyak yang tidak menggunakan alat pelindung diri seperti masker, kacamata kerja, sepatu kerja dan sarung tangan saat bekerja. Hanya mengandalkan baju dan celana dari rumah saja padahal lingkungan kerja banyak debu dan serpihan potongan kayu. Mereka merasakan aman dan nyaman karena belum pernah mengalami kecelakaan kerja. Tujuan dari program penyuluhan kesehatan ini adalah untuk mengetahui tingkat pengetahuan karyawan mebel tentang pentingnya keselamatan dan kesehatan saat bekerja dan pentingnya penggunaan alat pelindung diri. Metode yang dilakukan berupa penyuluhan kesehatan kepada 15 orang karyawan Mebel di Pusat Rehabilitasi Kusta Gema Kasih Galang. Evaluasi telah dilakukan dengan memberikan pre test dan post test. Hasil evaluasi sebelum dilakukan penyuluhan tentang keselamatan dan kesehatan kerja (K3) adalah mayoritas tingkat pengetahuan peserta kurang yaitu sebanyak 10 orang (66,6%) belum mengetahui konsep dari Keselamatan dan Kesehatan Kerja (K3) dan belum mengetahui tentang jenis-jenis Alat Pelindung Diri (APD). Setelah dilakukan penyuluhan tentang keselamatan dan kesehatan kerja (K3) menunjukkan adanya peningkatan pengetahuan karyawan sebanyak 13 orang (86,6%) yang memiliki pengetahuan baik dan menggunakan alat pelindung diri saat bekerja. Perbandingan pengetahuan peserta sebelum dan sesudah dilakukan penyuluhan tentang keselamatan dan kesehatan kerja (K3) adalah terjadinya peningkatan pengetahuan peserta sebesar 73,3% untuk kategori baik.             Kata kunci: keselamatan dan kesehatan kerja; pusat rehabilitasi kusta gema kasih; alat pelindung diri ABSTRACTMany Furniture employee in the Gema Kasih Galang Leprosy Rehabilitation Center Furniture don’t use personal protective equipment such as masks, work glasses, work shoes and gloves at work.  Only rely on clothes and pants from home even though the work environment is full of dust and pieces of food.They feel safe and comfortable because they have never had an accident at work. The purpose of this health education program is to find out the level of knowledge of furniture employees about the importance of safety and health at work and the tmportance of using personal protective equipment. The method used is in the form of health education to 15 furniture employees at the Gema Kasih Galang Leprosy Rehabilitation Center. Evaluation has been done by giving pre test and post test. The results of the evaluation before counseling on occupational safety and health (K3) was that the majority of the participants’ knowledge level was lacking as many as10 people (66,6%) did not know the concept of occupational safety and health (K3) and did not know about the types of personal protective equipment (PPE). After counseling on occupational safety and health (K3) showed an increase in employee knowledge as many as 13 people (86.6%) who had good knowledge and used personal protective equipment while working. Comparison of knowledge of participants before and after counseling on occupational safety and health (K3) is an increase in participants’ knowledge of 73.3% for the good category.    Keywords: occupational safety and health; kasih galang leprosy rehabilitation center; personal protective equipment
The Relationship Of Smoking Behavior With Carboxyhemoglobin Levels In Active Smokers Rica Vera Tarigan
Science Midwifery Vol 10 No 1, October (2021): Science Midwifery
Publisher : Institute of Computer Science (IOCS)

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Abstract

Smoking behavior is still entrenched in Indonesian cause a variety of diseases and even death. Cigarettes have become necessities of life that can not be abandoned in everyday life. The smoking problem in essence has become a national problem, even international level. But most connoisseurs of cigarettes assume that smoking is a personal responsibility for the consequences caused. Scientific researchers revealed that smoking is the leading cause of premature death. Statistical data shows that 90% of deaths due to respiratory problems, 25% of deaths caused by coronary heart disease that is triggered by smoking. In cigarette smoke contains 4000 chemicals, one of which is carbonmonoksida (CO), which can disturb binding of oxygen with hemoglobin (Hb), which transformed into bonds HbCO. This research used a correlational analysis with a quantitative approach and cross-sectional study design. Samples used as many 100 respondents used purposive sampling technique. Samples fill out the questionnaire and measured HbCO levels in the blood HbCO qualitatively. Data were analyzed with univariate, bivariate with Product Moment correlation techniques, multivariate correlation analysis. The results showed that there is a correlation of smoking behavior (number of cigarettes smoked by the respondent, the respondent smoking duration and type of cigarettes consumed by the respondents) against HbCO levels. Smoking behavior (knowledge, attitudes, and actions on how cigarette smoking cigarettes made by respondents) have no correlation with HbCO levels.
UJI ANTIFERTILITAS EKSTRAK LIDAH BUAYA (Aloe Vera L.) TERHADAP KUANTITAS SPERMATOZOA DAN EKSPRESI CYCLOOXYGENASE-2 PADA TESTIS MENCIT (Mus musculusL.) Rica Vera; Dedy Sambahtra
Journal of Indonesian Medical Laboratory and Science Vol 3 No 1: April 2022
Publisher : Asosiasi Institusi Pendidikan Tinggi Teknologi Laboratorium Medik Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53699/joimedlabs.v3i1.65

Abstract

The family planning program needs to be carried out as an effort to reduce the rate of population growth. In this case the participation of men is very important and need research about natural ingredients that can be used as antifertility drugs. Aloe vera leaf (Aloe vera L.) is one of the plants that have an antifertility effect so that it can be used as a contraceptive for men. The purpose of this study was to determine the effect of ethanol extract  aloe vera leaves of the quantity of spermatozoa and the expression of Cyclooxygenase-2 (COX-2) in the testes of mice (Mus musculus L.). The research used four treatment groups, namely P0 as a control was given aquadest 0,5 mL, P1 was given extract 15 mg/25g body weight by oral, P2 was given extract 20 mg/25g body weight by oral, and P3 was given extract 25 mg/25g body weight by oral given for 4 weeks. The research used completely randomized sampling method and data were analyzed using One Way ANOVA followed by Bonferroni Post Hoc test 5%. Administration of ethanol extract aloe vera leaves resulted in a decreased sperm quantity and increase expression of COX-2 in the testes of mice so that aloe vera leaves had the opportunity as a herbal contraceptive for men.
Analysis Of Troponin T Examination Results In Acute Myocard Infark Patients In Santa Elisabeth Hospital Medan, 2022 Paska Ramawati Situmorang; Fransiskanes Manurung; Rica Vera Br.Tarigan
Jurnal EduHealth Vol. 13 No. 02 (2022): Jurnal eduHealth, December, 2022
Publisher : Sean Institute

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Abstract

Infarction Acute Myocardial (AMI) is damage to myocardial tissue due to severe ischemia that occurs suddenly. The incidence of heart disease undergoing inpatient and outpatient treatment in hospitals in Indonesia in 2019 was 239,548 people (WHO). IMA is included in the top 10 categories of non-communicable diseases that are the cause of death in hospitals throughout Indonesia, around 6.25%. Troponin T is a cardiac contractile regulatory protein molecule that can measure normal and abnormal levels to help diagnose AMI. The purpose of this study was to analyze troponin-T levels in AMI patients, and the average (percentage) results of troponin-t examinations in AMI patients at St.Elisabeth Hospital Medan 2022. This type of research is an observational descriptive designed. The sampling technique in this study is retrospective. The population are 240 people and the research sample are 93 people. The results of this study conduc on 93 patients show an average troponin T level of 13.07 ng/ml, SD 17.44949, most of the patients were 64 men (68.8%) and 29 women (31 ,2%) with the lowest age are 37 years and the highest are 79 years. The results show that 94.6% of AMI patients experienc an increase in troponin T levels. Patients with acute myocardial infarction when an infarction occurred, it will experience increased levels due to the release of the troponin T enzyme through membrane leakage due to necrosis, so it will show a peak value on examination. 
Overview of Blood Glucose Levels in Diabetes Mellitus Patients at UPT Medan Health Laboratory in 2022 Kelvin Sutirta Lase; Seri Rayani Bangun; Rica Vera Br Tarigan
Jurnal EduHealth Vol. 13 No. 02 (2022): Jurnal eduHealth, December, 2022
Publisher : Sean Institute

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Abstract

This study aims to determine the distribution of blood glucose levels in patients with diabetes mellitus. This type of research design is descriptive analytic. The population is obtain from outpatient medical record data for diabetes mellitus patients for the last 3 months from January to March 2022 with a total of 63 people. The sample of this study amount to 63 people. Data collection is obtained through medical record data and the results of examination of blood glucose levels. The results of this study find that respondents with high fasting blood glucose levels are 54 people (85.9%), the age range that suffer the most from diabetes mellitus was the age range of 65-74 years. The increase in blood glucose is due to genetic factors, immunological factors, immunological factors, environment, age, and obesity.
Identification Of Cholestrol Level Testing HDL And LDL In Hypertension Patients At Santa Elisabeth Medan Hospital Cornelius Manik; Putri Hartanti Hulu; Rica Vera Br Tarigan
Jurnal EduHealth Vol. 13 No. 02 (2022): Jurnal eduHealth, December, 2022
Publisher : Sean Institute

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Abstract

Number of people with hypertension continues to increase every year, there will be 1.5 billion people affected by hypertension, and every year 9, 4 million people died due to hypertension and its complications. The supporting examination for hypertension is an examination of the total levels of HDL and LDL cholesterol. This study aims to identify the examination of HDL and LDL cholesterol levels in patients with hypertension at Santa Elisabeth Hospital Medan 2022. This study used a descriptive analytic design. The population was obtained from medical record data, namely all inpatients and outpatients suffering from hypertension at Santa Elisabeth Hospital Medan for the last 3 months from January to March 2022 as many as 278 people with a total sample of 73 using purposive sampling technique. The examination was carried out using an automated chemistry analyzer Siemens dimension EXL 200. The results showed that more hypertensive respondents had abnormal HDL levels as many as 38 respondents (52.1%) and more than 69 respondents (94.5) had normal LDL levels. %). So from these results it was concluded that there was an abnormal increase in HDL levels and a decrease in LDL levels in patients with hypertension
Analisis Kadar Albumin Pra dan Post Hemodialisa pada Penderita Gagal Ginjal Kronik Seri Rayani Bangun; Elisa Putri Nadapdap; Rica Vera Br Tarigan
Jurnal Ilmiah PANNMED (Pharmacist, Analyst, Nurse, Nutrition, Midwivery, Environment, Dentist) Vol. 17 No. 3 (2022): Jurnal Ilmiah PANNMED Periode September- Desember 2022
Publisher : Poltekkes Kemenkes Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (380.032 KB) | DOI: 10.36911/pannmed.v17i3.1506

Abstract

Chronic renal failure (CKD) is a progressive decline in kidney function so that it cannot maintain hemostasis in the body, in order to maintain hemostasis in the body, hemodialysis is carried out in patients with kidney failure, to replace kidney function. Examination of albumin is serum or plasma taken from venous blood. The purpose of this study was to analyze albumin levels in patients with chronic renal failure pre and post hemodialysis at Santa Elisabeth Hospital Medan. This research method is descriptive. The population in this study were 178 patients with a total sample of 64 respondents. The method used to examine albumin levels is Bromocresol Green (BCG). The results showed that pre-hemodialysis albumin levels in patients with chronic renal failure had an average of 3.080. g/dL. Post-hemodialysis albumin levels have an average of 3.683 g/dL. Based on the examination of albumin levels in patients with chronic renal failure pre and post hemodialysis, it was found that albumin levels had increased within normal limits. Thus, patients with chronic kidney failure undergoing hemodialysis check their blood albumin levels to avoid hypoalbumin and routinely consult nutrition.