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All Journal Jurnal Penelitian Pendidikan IPA (JPPIPA) Journal Health & Science : Gorontalo Journal Health and Science Community Jurnal Maternitas Kebidanan Jurnal Aisyah : Jurnal Ilmu Kesehatan AVERROUS: Jurnal Kedokteran dan Kesehatan Malikussaleh PRIMER (Prima Medical Journal)
Maya Sari Mutia
Universitas Prima Indonesia
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Dentistry Education Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Physics Public Health Veterinary

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SUATU STUDI LITERATUR: AKTIVITAS ANTIDIABETIC DARI KULIT JERUK (Citrus sp.) Maya Sari Mutia; Chrismis Novalinda Ginting; OK Yulizal
Jurnal Maternitas Kebidanan Vol. 6 No. 2 (2021): Jurnal Maternitas Kebidanan
Publisher : Universitas Prima Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/jumkep.v6i2.2054

Abstract

Diabetes mellitus is a chronic metabolic disease, which is not able to secrete insulin in sufficient quantities or the body is unable to use insulin effectively so there is an excess glucose level and immediately suffer from some complications against the organs. Diabetes mellitus can be cured by herb utility which are thought to have compounds that has an antidiabetic effect. Therefore, this literature study discusses the antidiabetic activity of orange peel (Citrus sp.). The literature search was carried out on the Google Scholar search engine which used some keyword included antidiabetic, extract, orange peel, Citrus. In this literature study, there are inclusion and exclusion criteria for selecting journals as literature sources. The results of 12 literatures review that orange peel had antidiabetic activity by decrease blood glucose levels in some animal trials that had received an effective dose of orange peel extract in each of the reviewed studies. Hence, it can be concluded that various type of Citrus peels has antidiabetic effect.
DESCRIPTION OF THE LEVEL OF COMMUNITY KNOWLEDGE OF GENERIC DRUG AND BRANDED DRUG AT A PHARMACY MEDAN CITY DISTRICT Nini Tiatira Tobing; Maya Sari Mutia
Journal Health & Science : Gorontalo Journal Health and Science Community Vol 6, No 2 (2022): JULI: JOURNAL HEALTH AND SCIENCE : GORONTALO JOURNAL HEALTH AND SCIENCE COMMUNIT
Publisher : Gorontalo State University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35971/gojhes.v5i3.13917

Abstract

Abstrak Obat generik bermerek adalah obat yang telah diberi nama dagangnya oleh perusahaan dan umumnya kualitasnya sama dengan obat generik berlogo tetapi dengan harga yang relatif lebih tinggi. Kebaruan penelitian ini adalah meneliti tentang tingkat pengetahuan masyarakat terhadap obat generic dan obat merek dagang di apotik. Tujuan untuk mengetahui gambaran tingkat pengetahuan masyarakat terhadap obat generik dan obat merek dagang di apotek Kecamatan Medan Kota. Penelitian ini merupakan penelitian deskriptif dengan pendekatan cross sectional. Pengambilan data dilakukan dengan teknik accidental sampling pada 192 responden. Analisa data univariat. Hasil yang diperoleh dari 192 masyarakat di apotek Kecamatan Medan Kota, umur terbanyak adalah 18-29 tahun yaitu 69 orang (35,9%), jenis kelamin terbanyak adalah perempuan yaitu 102 orang (53,1%), pendidikan terbanyak adalah perguruan tinggi yaitu 130 orang (67,7%), dan pekerjaan terbanyak adalah wiraswasta yaitu 48 orang (25,0%), serta dari 192 masyarakat di apotek Kecamatan Medan Kota, tingkat pengetahuan masyarakat kategori baik sebanyak 33 reponden (17,2%), tingkat pengetahuan kategori cukup sebanyak 134 responden (69,8%), dan tingkat pengetahuan kategori kurang baik sebanyak 25 responden (13%). Kesimpulan, bahwa umur terbanyak adalah 18-29 tahun, jenis kelamin terbanyak adalah perempuan, pendidikan terbanyak adalah perguruan tinggi, dan pekerjaan terbanyak adalah wiraswasta, serta tingkat pengetahuan masyarakat terhadap obat generik dan obat merek dagang di apotek Kecamatan Medan Kota masih dalam kategori cukup. Kata Kunci : Obat Generik; Obat Merek Dagang; Tingkat Pengetahuan Masyrakat. AbstractBranded generic drugs are drugs that have been given a trade name by the company and generally have the same quality as generic drugs with the logo but at a relatively higher price. The novelty of this research is the description of the level of public knowledge of generic drugs and trademarked drugs in pharmacies. The purpose of this study is to describe the level of public knowledge of generic drugs and trademarked drugs in pharmacies in Medan Kota District. This research is a descriptive study with a cross sectional approach. Data collection was done by accidental sampling technique on 192 respondents. Univariate data analysis. The results obtained from 192 people in pharmacies in Medan Kota District, the most age were 18-29 years, namely 69 people (35.9%), the most gender were women, namely 102 people (53.1%), the most education was college, namely 130 people (67.7%), and the most occupations are self-employed, namely 48 people (25.0%), and from 192 people in the Medan City district pharmacy, the level of community knowledge is in the good category as many as 33 respondents (17.2%), the level of knowledge in the good category is 33 respondents (17.2%). sufficient knowledge category as many as 134 respondents (69.8%), and the level of knowledge is not good category as many as 25 respondents (13%). The conclusion is that the most age is 18-29 years, the most gender is female, the most education is college, and the most occupation is self-employed, and the level of public knowledge of generic drugs and trademarked drugs in pharmacies in Medan Kota District is still in the sufficient category.
Formulation and Physical Characteristics of Effervescent Granules from Sunkist Peels Ethanol Extract Maya Sari Mutia; Stephanie Raibalaki; Siti Rahma; Anita Zahra; Ali Napiah Nasution; Widya Yanti Sihotang
Jurnal Aisyah : Jurnal Ilmu Kesehatan Vol 8, No 2: June 2023
Publisher : Universitas Aisyah Pringsewu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30604/jika.v8i3.2087

Abstract

Citrus fruit has a sweet taste and attractive shape, which is also enriched various health benefits. Some studies have been performed to investigate the pharmacology effects from the Sunkist peel extract. However, none of this study was look for the development of pharmaceutical products. Hence this study was performed to investigate the pharmaceutical formulation as an effervescent granule from Sunkist peel extract. This study was an experimental study to investigate the optimum formulation that was made by wet granulation methods. There were three formulation of Sunkist peel extract effervescent granule that were combination of organic acids (citric acid and tartaric acid), sodium bicarbonate as base compound, and some sweetener including aspartame, lactose, and mannitol. After that, the formulation was evaluated the physical properties including organoleptic, flow rate, dissolution time, foam height, pH, and angle of repose. The result of this study showed that these three formulations of Sunkist Peel extract effervescent granule showed significant different in almost all of physical properties including: flow rate (P-Value = 0.027), dissolution time (P-Value less than 0.05), foam height (P-Value = 0.004), and angle of repose (P-Value: 0.043), except the degree of acidity or pH (P-Value = 0.128). Third formulation (F3) reveals the best physical properties as a Sunkist peel extract effervescent granule. Overall, it can be concluded that the third and second formulation fulfils a well physical properties of effervescent granule for Sunkist peel extract.
Uji Ekstrak Etanol Pakkat Terhadap Gambaran Histopatologi Pankreas Tikus Wistar Jantan Yang Diinduksi Aloksan Roland Daniel Theodore Amudi Matondang; Aleksander Marganda Sidebang; Yolanda Eliza Putri Lubis; Maya Sari Mutia; Stevenie -
PRIMER (Prima Medical Journal) Vol. 8 No. 1 (2023): Edisi April
Publisher : Universitas Prima Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/pmj.v8i1.3239

Abstract

Objective: This take a look at ambitions to study the effectiveness of pakkat extract on the histopathological functions of the pancreas of male Wistar rats (Rattus novergicus) prompted with the aid of alloxan. methods: The layout used was an experimental layout with a pre-take a look at and publish-check randomized manipulate layout, the pattern used became 25 hyperglycemic rats divided into 5 groups: terrible manage (given NaCMC), high quality control (metformin), remedy 1 ( pakkat extract 125 mg/weight), remedy 2 (packkat extract 250 mg/ weight), treatment 3 (packkat extract 500 mg/weight) for 14 days. outcomes: The outcomes showed that pakkat extract (Calamus caesius blume) with tracking doses of one hundred twenty five mg/weight and 250 mg/weight for 14 days continuously ought to lessen the advent of alloxan-caused damage to the pancreas of male Wistar rats, which became characterized with the aid of reduced cellular look. infection, decreased interstitial bleeding, and reduced vascular congestion. conclusion: Pakkat extract (Calamus caesius blume) in positive doses can repair the harm to the structure of histopathological picture in male Wistar rats prompted via alloxan with the finest dose of 250 mg/weight.
Determination of Patient Satisfaction with Dental and Oral Care Services for Clinical Students at Dental and Oral Hospital Prima Medan Silvi Tiara Dewi; Chrismis Novalinda Ginting; Maya Sari Mutia
Jurnal Penelitian Pendidikan IPA Vol 9 No SpecialIssue (2023): UNRAM journals and research based on science education, science applic
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v9iSpecialIssue.6459

Abstract

The aim of this research is to determine the determinants of patient satisfaction with dental and oral care services for clinical students at Dental and Oral Hospital Prima Medan. This type of research is quantitative research with a cross-sectional design. The sample in this study was 200 patients. Data analysis in this study used univariate, bivariate and multivariate analysis. The results of the study showed that there was a correlation between patient satisfaction with dental and oral care services among clinical students at Dental and Oral Hospital Prima Medan based on time, procedure, attitude, level of knowledge, p < 0.05 (0.000 < 0.05) with a very high correlation level strong. There is a correlation between patient satisfaction with dental and oral care services among clinical students at Dental and Oral Hospital Prima Medan based on communication and spatial comfort, p < 0.05 (0.000 < 0.05) with a strong correlation level. The influence of service time, procedures, attitudes, level of knowledge, communication and spatial comfort on dental and oral care patient satisfaction among clinical students at Dental and Oral Hospital Prima Medan was 83.7%. The variable that most influences patient satisfaction with dental and oral care services for clinical students at Dental and Oral Hospital Prima Medan is the procedure variable
The Antiacne Activity of Sunkist Peels Methanol Extract in Propionibacterium Acne-Induced Acne Vulgaris Maya Sari Mutia; Etha Wilda Hasiani Damayanti; Tan Suyono; Widya Yanti Sihotang
AVERROUS: Jurnal Kedokteran dan Kesehatan Malikussaleh Averrous, Volume 9 No.2 November 2023
Publisher : Fakultas Kedokteran Universitas Malikussaleh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29103/averrous.v9i2.12320

Abstract

Treatment with acne vulgaris is a challenge because the complex pathophysiology of acne vulgaris. One of the natural products that potentially use as a herbal medicine is Sunkist peel. The peel of Sunkist is more inclined to end up as waste from domestic industries. The aim of this study was to investigate the antiacne activity of the Sunkist peel methanol extract gel in vivo study. The experimental study used by applied Sunkist peel extract gel to rats injected intradermally with Propionibacterium acne suspension. One hour before the injection of Propionibacterium acnes suspension, all rats were applied to a topical gel based on the group. Control, standard, Sunkist Peel Extract Gel-I, II, and III groups received gel base, clindamycin, 5%, 10%, and 15% of Sunkist peel extract gel, respectively. This study indicates the methanol extract of Sunkist orange peel with a yield of 8.73% revealed the presence of some phytochemicals, including alkaloids, flavonoids, tannins, and saponins. Sunkist orange peel methanol extract gel significantly reduced the size of acne vulgaris lesions after 7-14 days of extract application (p-value <0.05). It is in line with the histological study that the gel concentration increased, followed by the growth of the epidermal layer. This study sstrongly indicates that Sunkist orange peel methanol extract has an antiacne effect in a physically stable gel form.
Co-Authors Aleksander Marganda Sidebang Ali Napiah Nasution Anita Zahra Chrismis Novalinda Ginting Etha Wilda Hasiani Damayanti Nini Tiatira Tobing OK Yulizal Roland Daniel Theodore Amudi Matondang Silvi Tiara Dewi Siti Rahma Stephanie Raibalaki Stevenie - Tan Suyono Widya Yanti Sihotang Yolanda Eliza Putri Lubis