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Potensi Kitosan sebagai Edible Coating pada Buah Anggur Hijau (Vitis vinifera Linn) Hilma Hilma; Ahmad Fatoni; Dwi Puspita Sari
Jurnal Penelitian Sains Vol 20, No 1 (2018)
Publisher : Faculty of Mathtmatics and Natural Sciences

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (428.11 KB) | DOI: 10.56064/jps.v20i1.497

Abstract

A study has been conducted on influences of various chitosan concentrationas coating and storage time to Vitamin C concentration of green grape (Vitis vinifera L.) by dipping method. This study aims to de-termine the difference of chitosan concentration to physical characteristics, weight loss and vitamin C concen-tration of green grape. Chitosan coating was conducted on 50 grams of green grape by dipping method at var-ious concentration of chitosan that is 0%, 0,5%, 1%, 1,5% and 2% (w / v), kept on variation of one, four and seven day storage time. Determination of vitamin C concentration of green grape was done by UV-Vis spec-trophotometer measured at 256 nm wavelength with regression equation y = 0,0344 x + 0,101 and r = 0,998. Based on statistical test showed that chitosan concentration of 1% (w / v) with 4 days storage time is the most optimum because the chitosan layer is able to close all green grape pores, so the process of anaerobic and CO2 respiration can be inhibited by chitosan solution.
A Adsorbent of Chitosan Linked by Methylene Bridge and Schiff Base of 4,4-diaminodiphenyl Ether –vanillin : Synthesis, Characterization and Its Application After Reacted by Zn(II) Ion as Antibacterial Agent Ahmad Fatoni; Poedji Loekitowati Hariani; Hermansyah Hermansyah; Aldes Lesbani
Science and Technology Indonesia Vol. 3 No. 4 (2018): October
Publisher : Research Center of Inorganic Materials and Coordination Complexes, FMIPA Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1596.344 KB) | DOI: 10.26554/sti.2018.3.4.173-177

Abstract

The synthesis chitosan linked by methylene bridge-Schiff base of 4,4-diaminodiphenyl ether-vanillin (modified chitosan adsorbent) has been studied. The aims of this research were modification of chitosan with Schiff base of 4,4-diaminodiphenyl ether-vanillin and formaldehyde and its application as antibacterial agent after used as an adsorbent of Zn(II) ion. Characterization of modified chitosan adsorbent was conducted using FTIR spectroscopy. Process of adsorption were conducted at 0.15 g of modified chitosan adsorbent reacted by concentration of Zn(II) ion solution (pH 6, 150 mg/L, 50 mL), contact time at 150 min. and at room temperature (280C). Modified chitosan adsorbent after reacted by Zn(II) ion solution as antibacterial agent with paper disk method. The result showed that chitosan can be modified with Schiff base of 4,4-diaminodiphenyl ether-vanillin and formaldehyde to form chitosan linked methylene bridge and Schiff base of 4,4-diaminodiphenyl ether-vanillin. Antibacterial of chitosan and modified chitosan adsorbent were higher than modified chitosan adsorbent after reacted by Zn(II) ion. Keywords : modified chitosan, antibacterial agent
Evaluasi Mutu Penyimpanan Obat di Instalasi Farmasi RS. X Palembang Berdasarkan Standart Nasional Akreditasi Rumah Sakit Reza Agung Sriwijaya; Ahmad Fatoni; Anggraini Anggraini
Journal of Experimental and Clinical Pharmacy (JECP) Vol 2, No 1 (2022): Februari 2022
Publisher : Poltekkes Kemenkes Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52365/jecp.v2i1.371

Abstract

Pengelolaan  sediaan farmasi, alat kesehatan, dan Bahan Medis Habis Pakai (BMHP),salah satunya penyimpanan obat harus dapat menjamin kualitas dan keamanan sesuai dengan persyaratan kefarmasian. Penelitian ini bertujuan untuk mengetahui mutu penyimpanan obat berdasarkan Standar Akreditasi Nasional Rumah Sakit (SNARS) Jenis penelitian ini adalah non eksperimental,deskriptif dengan pengamatan langsung terhadap fasilitas penyimpanan obat. Pengumpulan data dengan cara pengamatan langsung dan wawancara dengan apoteker  di Instalasi Farmasi bagian penyimpanan obat rumah sakit X menggunakan lembar chek list ditabel pengamatan, kemudian dihitung persentasenya. hasil didapat Standar Operasional Prosedur Penyimpanan sebesar 100% (baik), kondisi sarana dan prasarana penyimpanan kesesuaian sebesar 93% (Baik) dan pengaturan penyimpanan obat kesesuaian sebesar 96% (Baik).Management of pharmaceutical preparations, medical devices, and medical consumables, one of which is drug storage must be able to guarantee quality and safety by pharmaceutical requirements. This study aims to determine the quality of drug storage based on the National Hospital Accreditation Standard (SNARS). This type of research is non-experimental, descriptive with direct observation of drug storage facilities. Collecting data by direct observation and interviews with pharmacists at the Warehouse divison of Pharmacy Installation of hospital X using a checklist sheet in the observation table, then the percentage is calculated. The results obtained are Standard Operating Procedures for Storage of 100% (good), the condition of facilities and infrastructure for storage of conformity is 93% (Good) and drug storage arrangements are of conformity of 96% (Good).
ZnO Nanoparticles and Its Interaction With Chitosan : Profile Spectra and Their Activity Against Bacterial Ahmad Fatoni; M. Arif Afrizal; Ade Arinia Rasyad; Nurlisa i Hidayat
JKPK (Jurnal Kimia dan Pendidikan Kimia) Vol 6, No 2 (2021): JKPK (Jurnal Kimia dan Pendidikan Kimia)
Publisher : Program Studi Pendidikan Kimia FKIP Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/jkpk.v6i2.48000

Abstract

The biosynthesis of ZnO nanoparticles and synthesis of chitosan- ZnO nanoparticles were studied. The aims of this research were biosynthesis of ZnO nanoparticles, synthesis of chitosan-ZnO nanoparticles, its characterization and, used as an antibacterial agent of Escherichia coli. ZnO nanoparticles were biosynthesized by reacting with ethanolic extract of guava seeds leaves (Psidium guajava L.) and zinc acetate dihydrate solution. Chitosan-ZnO nanoparticles were synthesized by the heating method. ZnO nanoparticles and chitosan-ZnO nanoparticles were characterized by FTIR spectroscopy and X-ray diffraction, respectively. The suspension of chitosan-ZnO nanoparticles was used as an antibacterial agent with a paper disk method. The result showed that the Zn-O group at ZnO nanoparticles was detected at a wavenumber 615.29 and 673.16 cm-1  The crystallite size of ZnO nanoparticles was 1.43 nm. The wavenumber of 617-655 cm-1 is the Zn-O group at the structure of the chitosan-ZnO nanoparticle. The average of diameter inhibition zone of chitosan-ZnO nanoparticles (1:2) at concentration 0.25 and 0.5 % (w/v) to Escherichia coli was 15.7 ± 1.0 and 18.3 ± 0.4 mm respectively. 
Biosintesis ZnO Nanopartikel dari Ekstrak Air Daun Jambu Biji (Psidium guajava L) dan Ion Zn2+ serta Interaksinya dengan Kitosan sebagai Antibakteri Escherichia coli Ahmad Fatoni; Hilma Hilma; Ade Arinia Rasyad; Selly Novriyanti; Nurlisa Hidayati
Jurnal Sains Farmasi & Klinis Vol 7, No 2 (2020): J Sains Farm Klin 7(2), Agustus 2020
Publisher : Fakultas Farmasi Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (950.892 KB) | DOI: 10.25077/jsfk.7.2.151-157.2020

Abstract

The biosynthesis of ZnO nanoparticles and chitosan-ZnO nanoparticles has been carried out. The aims of this research were to modify and characterize of chitosan-ZnO nanoparticles and their application as an antibacterial agent of Escherichia coli. The characterization of chitosan-ZnO nanoparticles was conducted by FTIR spectroscopy and X-Ray diffractometer. ZnO nanoparticle was synthesized by the reaction between leaf extract of the common guava (Psidium guajava L) and zinc acetate dihydrate. Chitosan-ZnO nanoparticles were synthesized by the reaction between chitosan and ZnO nanoparticles. The agar diffusion method was used to study the antibacterial activity of chitosan-ZnO nanoparticles. The result showed that the wavenumber of FTIR spectra chitosan-ZnO nanoparticles appeared at 3427 cm−1. The crystalline size of ZnO nanoparticles was 16.54 nm. The average inhibition zone of chitosan-ZnO nanoparticles at concentration 10,000; 5,000; and 2.500 mg/L were 30.57 ± 0.87; 25.97 ± 1.42; and 23.10 ± 1.61 mm, respectively. The higher the concentration of chitosan-ZnO nanoparticles, the greater the inhibition zone.
Synthesis, Characterization of Cellulose Modified with 2-Mercaptobenzothiazole and Its Adsorption To Cu(II) Ion in Aqueous Solution Ahmad Fatoni; Soerja Koesnarpadi; Nurlisa Hidayati
Indonesian Journal of Chemistry Vol 15, No 2 (2015)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (338.644 KB) | DOI: 10.22146/ijc.21214

Abstract

The modification of cellulose with 2-mercaptobenzhotiazole (MBT) through grafting and impregnating methods has been done. Modified cellulose used as adsorbent for Cu(II) ion in aqueous solution. The aims of research were modification cellulose with 3-chloropropyltrimethoxysilane and 2-mercaptobenzhotiazole (MBT), characterization of the modified cellulose with FTIR, SEM and XRD and adsorption study between cellulose-MBT adsorbent with Cu(II) ion in aqueous solution. The adsorbent of cellulose-MBT was synthesized by reflux process. Adsorption study between cellulose-MBT adsorbent with Cu(II) ion was investigated based on influence of pH solution, interaction time and initial concentration of Cu(II) ion. The result showed that activated cellulose can be modified with MBT to become cellulose-MBT adsorbent. The functional group of –C=N appeared at wavenumber 1658 cm-1 attributed to functional group of -C=N- is Schiff base of MBT. Presence functional group of S-H at cellulose-MBT adsorbent was not detected. The surface morphology of cellulose-MBT adsorbent after being interacted with Cu(II) ion was different before being interacted with Cu(II) ion. The diffractogram of cellulose-MBT adsorbent has similarity with cellulose-MBT adsorbent-Cu(II) ion. The optimum adsorption of Cu(II) ion was observed at pH 7.0 and 150 min of interaction time. Percentage of Cu(II) ion was absorbed by cellulose-MBT adsorbent tended to be constant after Cu(II) ion concentration 100 ppm.
Pembuatan dan Penyuluhan Virgin Coconut Oil di Desa Tanjung Seteko Indralaya dan Manfaatnya Untuk Kesehatan Nurlisa Hidayati; Hermansyah Hermansyah; Ferlinahayati Ferlinahayati; Addy Rachmat; Ahmad Fatoni
Jurnal Kreativitas Pengabdian Kepada Masyarakat (PKM) Vol 5, No 7 (2022): Volume 5 No 7 Juli 2022
Publisher : Universitas Malahayati Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jkpm.v5i7.6192

Abstract

 ABSTRAK Telah dilaksanakan kegiatan pengabdian kepada masyarakat Desa Tanjung Seteko Indralaya. Tujuan kegiatan ini adalah untuk memberikan informasi kepada masyarakat tentang: pengolahan buah kelapa menjadi virgin coconut oil (VCO) dan demonstrasi pembuatan dan pemanfaatan VCO. Kegiatan Pengabdian kepada Masyarakat ini diikuti 20 orang ibu rumah tangga dan remaja putri yang berasal dari desa Tanjung Seteko. Kegiatan yang dilaksanakan adalah memperkenalkan teknologi pembuatan VCO. Selain itu dilakukan juga diskusi dan demonstrasi penggunaan VCO sebagai ramuan yang berguna bagi kesehatan. Penyuluhan yang dilakukan mendapat tanggapan yang positif dari masyarakat. Kegiatan diskusi dan tanya jawab juga mendapat perhatian yang tinggi dari masyarakat. Masyarakat merasa senang karena mendapatkan pengetahuan dan keterampilan tentang teknologi pembuatan VCO. Dengan diberikannya penyuluhan masyarakat juga menjadi faham cara membuat ramuan berbahan dasar VCO. Masyarakat juga berharap kegiatan pengabdian dapat berlangsung secara berkelanjutan, sehingga wawasan mereka akan terus bertambah baik. Kata Kunci: Pembuatan, Penyuluhan, VCO ABSTRACT Community service activities in Tanjung Seteko village Indralaya have been carried out. The purpose of this activity is to provide information to the public about: processing coconuts into virgin coconut oil (VCO) and demonstrations of making and using VCO. This community service activity was attended by 20 housewives and young women from Tanjung Seteko village. The activity carried out to introduce the technology of making Virgin Coconut Oil. In addition, discussions and demonstrations on the use of VCO as an ingredient that is useful for health were also held. The counseling carried out received a positive response from the community. Discussion and question and answer activities also received high attention from the community. People are happy because they get knowledge and skills about VCO manufacturing technology. By providing public education, they also understand how to make VCO-based ingredients. The community also hopes that service activities can take place in a sustainable manner, so that their knowledge will continue to improve. Keywords: Making, Counseling, VCO
Chitosan-CuO Nanoparticles as Antibacterial Shigella dysenteriae: Synthesis, Characterization, and In Vitro Study Ahmad Fatoni; Ade Chika Paramita; Budi Untari; Nurlisa Hidayati
Jurnal Kimia Sains dan Aplikasi Vol 23, No 12 (2020): Volume 23 Issue 12 Year 2020
Publisher : Chemistry Department, Faculty of Sciences and Mathematics, Diponegoro University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (3408.415 KB) | DOI: 10.14710/jksa.23.12.432-439

Abstract

The synthesis of chitosan- CuO nanoparticles was studied. This research’s aims were biosynthesis CuO nanoparticles, synthesis of chitosan-CuO nanoparticles, and used as an antibacterial agent of Shigella dysenteriae. CuO nanoparticles and chitosan-CuO nanoparticles were characterized by FTIR spectroscopy and X-ray diffraction, respectively. CuO nanoparticle was synthesized by the reaction between leaf extract of sweet star fruit (Averrhoa carambola L.) and copper sulfate pentahydrate. Chitosan-CuO nanoparticles were synthesized by a heating method. The suspension of chitosan-CuO nanoparticles was used as an antibacterial agent with a paper disk method. The result showed that the Cu-O group at CuO nanoparticles was detected at a wavenumber of 503, 619, 767, and 821 cm-1. The crystallite size of the CuO nanoparticles was 4.25 nm. Cu-O group bonded at N-H and O-H groups and detected at 3406 cm-1 from the FTIR spectra of chitosan-CuO nanoparticles. The average inhibition zone of chitosan-CuO nanoparticles at concentration 2.500, 5.000, 7.500, and 10.000 ppm to Shigella dysenteriae were 13.57 ± 1.55; 14.90 ± 1.20; 15.97 ± 0.76 and 17.03 ± 1.80 mm, respectively.
Synthesis and Characterization Chitosan-ZnO nanoparticle and Its Application as Antibacterial Agent of Staphylococus aureus ATCC 25923 Ahmad Fatoni; Ensiwi Munarsih; Kadek Asmadi; Nurlisa Hidayati
Science and Technology Indonesia Vol. 5 No. 1 (2020): January
Publisher : Research Center of Inorganic Materials and Coordination Complexes, FMIPA Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1652.629 KB) | DOI: 10.26554/sti.2020.5.1.1-5

Abstract

The synthesis of modified chitosan has been studied. The aims of this research were modification of chitosan with ZnO nanoparticle to form chitosan-ZnO nanoparticle and its application as antibacterial agent of Staphylococus aureus. Characterization of modified chitosan was conducted using FTIR spectroscopy and X-Ray diffractometer. ZnO nanoparticle was synthesized by leaf extract of Sirih hijau (piper betle L) and zinc acetate dihydrate. Modified chitosan was synthesized by chitosan and ZnO nanoparticle. Modified chitosan solution can act as antibacterial agent with paper disk method. The result showed that chitosan can be modified with ZnO nanoparticle and detected at wave number of 3427 cm−1. The crystalline size of ZnO nanoparticle is 16.47 nm. The average inhibition zone of chitosan-ZnO nanoparticle at concentration 10.000, 5.000 and 2.500 ppm are 28.87 ± 0.4 ; 24.93 ± 0.15 and 19.35 ± 0.3 mm respectively.
CuO Nanoparticles : Biosynthesis, Characterization and In Vitro Study Ahmad Fatoni; Reza Agung Sriwijaya; Umy Habiba; Nurlisa Hidayati
Science and Technology Indonesia Vol. 6 No. 1 (2021): January
Publisher : Research Center of Inorganic Materials and Coordination Complexes, FMIPA Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (2336.259 KB) | DOI: 10.26554/sti.2021.6.1.25-29

Abstract

The biosynthesis of CuO nanoparticles was studied. The aims of this research were biosynthesis CuO nanoparticles from Cu2+ion solution and leaves aquoeus extract of sweet star fruit and its in vitro study as antibacterial agent of Escherichia coli. CuO nanoparticles was characterized using FTIR spectroscopy and X-Ray diffractometer. CuO nanoparticles was synthesized by reaction between Cu2+ion solution and leaves aquoeus extract of sweet star fruit. Paper disk method was used as the application of the suspension of CuO nanoparticles. The result showed that Cu-O groups detected at wave number of 503, 619, 767 and 821 cm-1. Diffractogram of CuO nanoparticles had sharp and narrow diffraction peaks. The crystallite size of CuO nanoparticles was 4.25 nm. The average inhibition zone of CuO nanoparticles at concentration 10.000, 7.500, 5.000 and 2.500 ppm was 17.43 ± 1.81 ; 15.73 ± 0.40 ; 14.50 ± 2.96 and 9.67 ± 0.28 mm respectively.